Danio rerio

0 known processes

tra2a

transformer-2 alpha

(Aliases: zgc:64175,MGC64175)

tra2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of mrna splicing via spliceosome GO:0048024 3 0.974
Fly
alternative mrna splicing via spliceosome GO:0000380 1 0.880
Fly
organic cyclic compound metabolic process GO:1901360 301 0.544
Human Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.541
regulation of mrna processing GO:0050684 3 0.470
Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.426
nucleic acid metabolic process GO:0090304 244 0.408
Human Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.347
Human Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.346
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.312
Human Fly
regulation of primary metabolic process GO:0080090 311 0.305
Fly
heterocycle metabolic process GO:0046483 290 0.284
Human Fly
biosynthetic process GO:0009058 294 0.275
cellular aromatic compound metabolic process GO:0006725 295 0.275
Human Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.255
Human Fly
regulation of rna metabolic process GO:0051252 224 0.240
Fly
regulation of metabolic process GO:0019222 359 0.227
Fly
nitrogen compound metabolic process GO:0006807 319 0.225
Human Fly
larval development GO:0002164 2 0.225
regulation of macromolecule metabolic process GO:0060255 317 0.207
Fly
regulation of transcription dna templated GO:0006355 213 0.206
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.203
mrna splicing via spliceosome GO:0000398 10 0.202
Human Fly
regulation of gene expression GO:0010468 265 0.201
Fly
rna metabolic process GO:0016070 219 0.199
Human Fly
rna processing GO:0006396 25 0.196
Human Fly
regulation of cellular metabolic process GO:0031323 320 0.194
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.190
Fly
cellular macromolecule metabolic process GO:0044260 391 0.165
Human Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.158
rna splicing GO:0008380 16 0.150
Human Fly
cellular biosynthetic process GO:0044249 286 0.148
macromolecule biosynthetic process GO:0009059 227 0.141
mrna processing GO:0006397 14 0.137
Human Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.135
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.131
nucleic acid templated transcription GO:0097659 181 0.131
aromatic compound biosynthetic process GO:0019438 217 0.131
organic substance biosynthetic process GO:1901576 289 0.130
cellular nitrogen compound biosynthetic process GO:0044271 218 0.127
regulation of macromolecule biosynthetic process GO:0010556 225 0.127
nucleobase containing compound biosynthetic process GO:0034654 205 0.116
mrna metabolic process GO:0016071 20 0.113
Human Fly
negative regulation of biological process GO:0048519 304 0.113
transcription dna templated GO:0006351 181 0.112
embryo development ending in birth or egg hatching GO:0009792 271 0.108
neuromuscular synaptic transmission GO:0007274 2 0.103
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.103
regulation of nucleic acid templated transcription GO:1903506 213 0.101
cellular component disassembly GO:0022411 1 0.101
gene expression GO:0010467 252 0.097
Human Fly
regulation of rna biosynthetic process GO:2001141 213 0.091
locomotion GO:0040011 313 0.087
regulation of rna splicing GO:0043484 8 0.085
Fly
rna splicing via transesterification reactions GO:0000375 10 0.082
Human Fly
regulation of cellular biosynthetic process GO:0031326 245 0.081
head development GO:0060322 303 0.070
central nervous system development GO:0007417 387 0.069
maintenance of location GO:0051235 4 0.068
growth GO:0040007 174 0.065
brain development GO:0007420 293 0.064
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.063
positive regulation of rna biosynthetic process GO:1902680 57 0.062
modification dependent protein catabolic process GO:0019941 3 0.061
single organism metabolic process GO:0044710 217 0.060
signal transduction GO:0007165 455 0.058
regionalization GO:0003002 274 0.058
locomotor rhythm GO:0045475 3 0.057
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.057
heterocycle biosynthetic process GO:0018130 215 0.057
positive regulation of gene expression GO:0010628 71 0.057
ubiquitin dependent protein catabolic process GO:0006511 3 0.057
positive regulation of cellular process GO:0048522 201 0.056
positive regulation of biological process GO:0048518 253 0.055
meiotic chromosome segregation GO:0045132 3 0.055
regulation of biosynthetic process GO:0009889 250 0.055
positive regulation of biosynthetic process GO:0009891 68 0.054
rna biosynthetic process GO:0032774 181 0.053
aging GO:0007568 2 0.052
gamete generation GO:0007276 33 0.052
organelle organization GO:0006996 227 0.051
macromolecular complex disassembly GO:0032984 1 0.046
dorsal ventral pattern formation GO:0009953 125 0.046
meiotic nuclear division GO:0007126 4 0.045
positive regulation of cellular component biogenesis GO:0044089 3 0.044
negative regulation of metabolic process GO:0009892 86 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.043
regulation of meiotic cell cycle GO:0051445 1 0.043
protein complex disassembly GO:0043241 1 0.042
positive regulation of translation GO:0045727 1 0.042
cellular protein catabolic process GO:0044257 4 0.041
positive regulation of protein complex assembly GO:0031334 2 0.041
regulation of protein complex disassembly GO:0043244 1 0.041
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.041
regulation of biological quality GO:0065008 263 0.039
sensory organ development GO:0007423 393 0.039
cell surface receptor signaling pathway GO:0007166 325 0.039
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.038
positive regulation of rna metabolic process GO:0051254 59 0.038
cellular component assembly GO:0022607 170 0.037
multicellular organismal reproductive process GO:0048609 35 0.037
protein metabolic process GO:0019538 183 0.036
cellular component biogenesis GO:0044085 178 0.035
establishment of localization GO:0051234 244 0.035
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.034
embryonic organ development GO:0048568 381 0.034
rna localization GO:0006403 4 0.034
proteasomal protein catabolic process GO:0010498 2 0.034
regulation of circadian rhythm GO:0042752 4 0.033
transcription from rna polymerase ii promoter GO:0006366 80 0.033
mrna catabolic process GO:0006402 6 0.033
hemopoiesis GO:0030097 183 0.032
cellular component morphogenesis GO:0032989 336 0.032
meiotic cell cycle process GO:1903046 3 0.031
vasculature development GO:0001944 278 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.031
multi organism process GO:0051704 134 0.031
positive regulation of metabolic process GO:0009893 108 0.031
regulation of synapse organization GO:0050807 3 0.031
positive regulation of cell cycle GO:0045787 3 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.030
positive regulation of macromolecule metabolic process GO:0010604 93 0.030
regulation of synapse assembly GO:0051963 3 0.030
positive regulation of nucleic acid templated transcription GO:1903508 57 0.030
response to chemical GO:0042221 320 0.030
segmentation GO:0035282 97 0.029
dna templated transcription elongation GO:0006354 3 0.029
phagocytosis GO:0006909 3 0.029
hematopoietic or lymphoid organ development GO:0048534 191 0.029
developmental growth GO:0048589 166 0.029
single organism localization GO:1902578 225 0.028
regulation of stem cell differentiation GO:2000736 4 0.028
negative regulation of synapse assembly GO:0051964 2 0.028
macromolecular complex subunit organization GO:0043933 74 0.028
regulation of cellular component organization GO:0051128 86 0.027
stem cell maintenance GO:0019827 4 0.027
regulation of protein ubiquitination GO:0031396 3 0.027
regulation of binding GO:0051098 3 0.027
reproduction GO:0000003 40 0.026
Fly
anterior posterior pattern specification GO:0009952 152 0.026
atp catabolic process GO:0006200 4 0.025
pole plasm assembly GO:0007315 4 0.025
negative regulation of gene expression GO:0010629 65 0.025
immune system development GO:0002520 191 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
dna templated transcription initiation GO:0006352 1 0.025
regulation of protein catabolic process GO:0042176 1 0.025
chordate embryonic development GO:0043009 271 0.024
negative regulation of cellular process GO:0048523 283 0.024
regulation of mrna metabolic process GO:1903311 6 0.024
Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.024
lipid storage GO:0019915 1 0.024
positive regulation of transcription dna templated GO:0045893 57 0.024
generation of neurons GO:0048699 385 0.023
multi organism reproductive process GO:0044703 36 0.023
positive regulation of muscle cell differentiation GO:0051149 1 0.023
organic acid metabolic process GO:0006082 31 0.023
regulation of dna templated transcription elongation GO:0032784 3 0.023
regulation of cytokine production GO:0001817 3 0.023
blood vessel development GO:0001568 246 0.023
regulation of tube size GO:0035150 2 0.023
multicellular organism growth GO:0035264 4 0.023
rna stabilization GO:0043489 4 0.022
cellular macromolecule catabolic process GO:0044265 12 0.022
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.022
compound eye development GO:0048749 2 0.022
blood vessel morphogenesis GO:0048514 216 0.021
regulation of protein metabolic process GO:0051246 56 0.021
chemosensory behavior GO:0007635 1 0.021
regulation of protein complex assembly GO:0043254 3 0.021
spermatid differentiation GO:0048515 2 0.021
response to stress GO:0006950 263 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
eye development GO:0001654 277 0.021
positive regulation of ras protein signal transduction GO:0046579 1 0.020
nuclear transport GO:0051169 4 0.020
adult behavior GO:0030534 2 0.020
protein polymerization GO:0051258 4 0.020
muscle structure development GO:0061061 196 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.020
spermatid development GO:0007286 2 0.019
negative regulation of developmental process GO:0051093 65 0.019
oocyte anterior posterior axis specification GO:0007314 4 0.019
posttranscriptional regulation of gene expression GO:0010608 14 0.019
regulation of cell shape GO:0008360 1 0.019
single organism organelle organization GO:1902589 199 0.019
developmental growth involved in morphogenesis GO:0060560 86 0.019
intracellular mrna localization GO:0008298 1 0.019
chromosome organization involved in meiosis GO:0070192 1 0.019
cell projection morphogenesis GO:0048858 244 0.019
organic substance catabolic process GO:1901575 28 0.019
catabolic process GO:0009056 32 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
angiogenesis GO:0001525 158 0.018
actin polymerization or depolymerization GO:0008154 2 0.018
neuron differentiation GO:0030182 353 0.018
regulation of multicellular organism growth GO:0040014 4 0.018
regulation of response to stimulus GO:0048583 269 0.018
stem cell division GO:0017145 1 0.018
development of primary female sexual characteristics GO:0046545 4 0.018
rna transport GO:0050658 2 0.018
regulation of developmental process GO:0050793 247 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
response to external biotic stimulus GO:0043207 97 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
stem cell proliferation GO:0072089 4 0.017
positive regulation of dna templated transcription elongation GO:0032786 1 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
nucleic acid transport GO:0050657 2 0.017
regulation of receptor activity GO:0010469 2 0.017
transport GO:0006810 220 0.017
negative regulation of catalytic activity GO:0043086 21 0.016
cell substrate junction assembly GO:0007044 2 0.016
synaptic vesicle endocytosis GO:0048488 1 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
somite development GO:0061053 96 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
axis specification GO:0009798 43 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.016
neuroblast proliferation GO:0007405 2 0.016
regulation of protein polymerization GO:0032271 2 0.016
oxoacid metabolic process GO:0043436 31 0.015
positive regulation of catabolic process GO:0009896 4 0.015
muscle organ development GO:0007517 101 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
maternal determination of anterior posterior axis embryo GO:0008358 4 0.015
synaptic vesicle recycling GO:0036465 1 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
female gonad development GO:0008585 4 0.015
regulation of cell communication GO:0010646 232 0.015
single organism reproductive process GO:0044702 40 0.015
lamellipodium assembly GO:0030032 1 0.015
golgi vesicle transport GO:0048193 3 0.014
entrainment of circadian clock GO:0009649 2 0.014
gastrulation GO:0007369 208 0.014
regulation of reproductive process GO:2000241 4 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
cellular respiration GO:0045333 3 0.014
single fertilization GO:0007338 3 0.014
positive regulation of transport GO:0051050 2 0.014
cellular response to external stimulus GO:0071496 2 0.014
protein import GO:0017038 3 0.014
cell cell signaling GO:0007267 52 0.014
single organism behavior GO:0044708 24 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
response to external stimulus GO:0009605 264 0.014
lamellipodium organization GO:0097581 1 0.014
regulation of cell activation GO:0050865 1 0.014
regeneration GO:0031099 91 0.013
axon development GO:0061564 166 0.013
sexual reproduction GO:0019953 36 0.013
germ cell development GO:0007281 22 0.013
cell aging GO:0007569 2 0.013
neuron development GO:0048666 262 0.013
heart development GO:0007507 313 0.013
negative regulation of cellular biosynthetic process GO:0031327 55 0.013
actin filament polymerization GO:0030041 2 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
retina development in camera type eye GO:0060041 146 0.013
protein dephosphorylation GO:0006470 3 0.013
multicellular organism reproduction GO:0032504 35 0.013
protein complex subunit organization GO:0071822 46 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
synaptic vesicle transport GO:0048489 1 0.013
ribosomal small subunit biogenesis GO:0042274 2 0.013
synaptic transmission GO:0007268 35 0.013
histone deacetylation GO:0016575 2 0.013
macromolecule catabolic process GO:0009057 15 0.013
somitogenesis GO:0001756 87 0.013
mitochondrion organization GO:0007005 4 0.013
single organism transport GO:0044765 206 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of signaling GO:0023051 235 0.012
response to glucose GO:0009749 3 0.012
3 utr mediated mrna stabilization GO:0070935 3 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
single organism nuclear import GO:1902593 3 0.012
sex determination GO:0007530 1 0.012
Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
male meiosis GO:0007140 2 0.012
cellular protein complex disassembly GO:0043624 1 0.012
negative regulation of biosynthetic process GO:0009890 55 0.012
amine metabolic process GO:0009308 2 0.012
energy reserve metabolic process GO:0006112 2 0.012
microtubule based process GO:0007017 60 0.012
protein homooligomerization GO:0051260 3 0.012
female gamete generation GO:0007292 14 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
protein targeting to nucleus GO:0044744 3 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
response to abiotic stimulus GO:0009628 122 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
cellular response to starvation GO:0009267 1 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
cellular protein modification process GO:0006464 100 0.011
meiosis i GO:0007127 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
system process GO:0003008 185 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
positive regulation of cytokine production GO:0001819 2 0.011
regulation of calcium ion transport GO:0051924 2 0.011
circadian sleep wake cycle process GO:0022410 2 0.011
regulation of chromosome segregation GO:0051983 1 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
negative regulation of myeloid cell differentiation GO:0045638 1 0.011
stem cell differentiation GO:0048863 117 0.011
positive regulation of rna splicing GO:0033120 1 0.011
microtubule organizing center organization GO:0031023 1 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
cellular catabolic process GO:0044248 27 0.011
cytoskeleton organization GO:0007010 96 0.011
response to other organism GO:0051707 97 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
regulation of metal ion transport GO:0010959 4 0.011
camera type eye development GO:0043010 222 0.011
cell morphogenesis GO:0000902 289 0.011
cytoplasm organization GO:0007028 4 0.011
regulation of signal transduction GO:0009966 225 0.011
negative regulation of rna metabolic process GO:0051253 48 0.011
neuron projection development GO:0031175 180 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
protein import into nucleus GO:0006606 3 0.011
interspecies interaction between organisms GO:0044419 4 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
negative regulation of catabolic process GO:0009895 3 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
entrainment of circadian clock by photoperiod GO:0043153 1 0.011
behavior GO:0007610 74 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
wound healing GO:0042060 90 0.010
nuclear export GO:0051168 1 0.010
regulation of protein binding GO:0043393 3 0.010
positive regulation of epithelial cell proliferation GO:0050679 1 0.010
lipid homeostasis GO:0055088 3 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
cell matrix adhesion GO:0007160 4 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.010
mrna stabilization GO:0048255 4 0.010
germ line stem cell maintenance GO:0030718 2 0.010
macromolecule deacylation GO:0098732 3 0.010
negative regulation of rna splicing GO:0033119 1 0.010
negative regulation of translation GO:0017148 1 0.010
cellular amine metabolic process GO:0044106 2 0.010
cellular carbohydrate metabolic process GO:0044262 4 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010

tra2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
musculoskeletal system disease DOID:17 0 0.029
myopathy DOID:423 0 0.019
muscular disease DOID:0080000 0 0.019
muscle tissue disease DOID:66 0 0.019
nervous system disease DOID:863 0 0.013
motor neuron disease DOID:231 0 0.010
central nervous system disease DOID:331 0 0.010
amyotrophic lateral sclerosis DOID:332 0 0.010
neurodegenerative disease DOID:1289 0 0.010