Danio rerio

0 known processes

sb:eu854

sb:eu854

sb:eu854 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.174
regulation of protein localization to nucleus GO:1900180 2 0.132
lipid storage GO:0019915 1 0.097
aging GO:0007568 2 0.083
nucleocytoplasmic transport GO:0006913 4 0.082
single organism localization GO:1902578 225 0.081
cellular component morphogenesis GO:0032989 336 0.075
regulation of metal ion transport GO:0010959 4 0.074
positive regulation of cellular component biogenesis GO:0044089 3 0.072
positive regulation of catabolic process GO:0009896 4 0.072
maintenance of location GO:0051235 4 0.069
regulation of gtp catabolic process GO:0033124 2 0.067
protein localization to nucleus GO:0034504 3 0.065
regulation of anatomical structure morphogenesis GO:0022603 130 0.063
nuclear transport GO:0051169 4 0.062
protein import GO:0017038 3 0.060
cell substrate adhesion GO:0031589 4 0.059
protein import into nucleus GO:0006606 3 0.058
regulation of protein transport GO:0051223 3 0.058
cellular carbohydrate metabolic process GO:0044262 4 0.057
cellular ketone metabolic process GO:0042180 11 0.057
cell matrix adhesion GO:0007160 4 0.057
acylglycerol homeostasis GO:0055090 2 0.057
single organism nuclear import GO:1902593 3 0.056
cell part morphogenesis GO:0032990 246 0.054
cellular response to extracellular stimulus GO:0031668 2 0.051
establishment of protein localization to organelle GO:0072594 4 0.051
gene expression GO:0010467 252 0.049
positive regulation of transport GO:0051050 2 0.049
regulation of calcium ion transport GO:0051924 2 0.049
lateral line system development GO:0048925 76 0.049
positive regulation of secretion by cell GO:1903532 1 0.048
regulation of protein import into nucleus GO:0042306 2 0.047
regulation of cytoplasmic transport GO:1903649 4 0.047
adherens junction organization GO:0034332 4 0.047
positive regulation of nucleoside metabolic process GO:0045979 1 0.045
gtp metabolic process GO:0046039 4 0.044
protein targeting to nucleus GO:0044744 3 0.043
establishment of protein localization to plasma membrane GO:0090002 1 0.043
long chain fatty acid metabolic process GO:0001676 1 0.043
establishment of localization GO:0051234 244 0.042
regulation of rho protein signal transduction GO:0035023 2 0.042
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.042
nuclear import GO:0051170 3 0.042
metal ion transport GO:0030001 58 0.041
guanosine containing compound metabolic process GO:1901068 4 0.040
lipid homeostasis GO:0055088 3 0.040
response to chemical GO:0042221 320 0.039
regulation of cell matrix adhesion GO:0001952 1 0.039
positive regulation of cellular catabolic process GO:0031331 3 0.039
regulation of purine nucleotide catabolic process GO:0033121 2 0.038
response to drug GO:0042493 3 0.038
regulation of cell substrate adhesion GO:0010810 1 0.038
protein localization to plasma membrane GO:0072659 1 0.038
positive regulation of gtp catabolic process GO:0033126 1 0.037
intestinal absorption GO:0050892 2 0.037
positive regulation of cytoskeleton organization GO:0051495 3 0.037
response to nutrient GO:0007584 3 0.036
regulation of hormone secretion GO:0046883 2 0.036
cellular amine metabolic process GO:0044106 2 0.036
regulation of stem cell differentiation GO:2000736 4 0.036
regulation of nucleocytoplasmic transport GO:0046822 2 0.036
phagocytosis GO:0006909 3 0.035
negative regulation of cytoplasmic transport GO:1903650 2 0.035
gtp catabolic process GO:0006184 2 0.035
cellular response to nutrient levels GO:0031669 2 0.034
lipid oxidation GO:0034440 1 0.034
organic acid metabolic process GO:0006082 31 0.033
oxoacid metabolic process GO:0043436 31 0.033
gastrulation GO:0007369 208 0.033
positive regulation of gtpase activity GO:0043547 1 0.032
regulation of nucleotide catabolic process GO:0030811 2 0.031
positive regulation of cellular process GO:0048522 201 0.031
epidermis development GO:0008544 48 0.031
positive regulation of cell matrix adhesion GO:0001954 1 0.031
carboxylic acid metabolic process GO:0019752 22 0.031
regulation of dendrite development GO:0050773 3 0.031
positive regulation of nucleotide catabolic process GO:0030813 1 0.030
cation transport GO:0006812 81 0.030
regulation of dendrite morphogenesis GO:0048814 3 0.030
transport GO:0006810 220 0.030
cellular response to external stimulus GO:0071496 2 0.030
hematopoietic or lymphoid organ development GO:0048534 191 0.030
cytokinesis GO:0000910 3 0.030
regulation of blood pressure GO:0008217 1 0.030
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.030
cognition GO:0050890 1 0.029
regulation of multicellular organismal development GO:2000026 223 0.029
regulation of metabolic process GO:0019222 359 0.029
signal transduction GO:0007165 455 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
regulation of cytokine production GO:0001817 3 0.028
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.028
regulation of tube size GO:0035150 2 0.027
regulation of binding GO:0051098 3 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
regulation of intracellular protein transport GO:0033157 3 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.026
cilium morphogenesis GO:0060271 85 0.026
secondary metabolic process GO:0019748 3 0.026
regulation of carbohydrate metabolic process GO:0006109 4 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
amine metabolic process GO:0009308 2 0.026
embryo development ending in birth or egg hatching GO:0009792 271 0.026
lateral line development GO:0048882 66 0.026
positive regulation of cell adhesion GO:0045785 1 0.026
negative regulation of intracellular protein transport GO:0090317 3 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
hormone transport GO:0009914 2 0.025
regulation of developmental process GO:0050793 247 0.025
cell morphogenesis GO:0000902 289 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
carbohydrate homeostasis GO:0033500 1 0.025
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.025
cellular nitrogen compound metabolic process GO:0034641 290 0.024
regulation of gtpase activity GO:0043087 2 0.024
cellular localization GO:0051641 97 0.024
regulation of cell communication GO:0010646 232 0.024
negative regulation of epithelial cell proliferation GO:0050680 1 0.023
locomotion GO:0040011 313 0.023
hormone secretion GO:0046879 2 0.023
positive regulation of secretion GO:0051047 1 0.023
regulation of cell development GO:0060284 100 0.023
cellular protein catabolic process GO:0044257 4 0.023
segmentation GO:0035282 97 0.023
cell projection organization GO:0030030 284 0.023
digestive system development GO:0055123 289 0.023
protein heterooligomerization GO:0051291 1 0.023
guanosine containing compound catabolic process GO:1901069 2 0.022
regulation of systemic arterial blood pressure GO:0003073 1 0.022
negative regulation of kinase activity GO:0033673 4 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.021
negative regulation of intracellular transport GO:0032387 3 0.021
protein secretion GO:0009306 1 0.021
chordate embryonic development GO:0043009 271 0.021
skeletal system development GO:0001501 181 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
cellular response to organic cyclic compound GO:0071407 38 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
regulation of primary metabolic process GO:0080090 311 0.021
homeostatic process GO:0042592 142 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
negative regulation of signal transduction GO:0009968 94 0.021
stem cell maintenance GO:0019827 4 0.020
somite development GO:0061053 96 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
positive regulation of cell cycle GO:0045787 3 0.020
peptide transport GO:0015833 1 0.020
regulation of protein complex assembly GO:0043254 3 0.020
negative regulation of protein transport GO:0051224 3 0.020
regulation of biological quality GO:0065008 263 0.019
cell motility GO:0048870 244 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
glucose homeostasis GO:0042593 1 0.019
macromolecule modification GO:0043412 111 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
sensory organ development GO:0007423 393 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
positive regulation of ras gtpase activity GO:0032320 1 0.019
digestive tract development GO:0048565 265 0.018
ion transport GO:0006811 114 0.018
aflatoxin b1 metabolic process GO:0043390 1 0.018
negative regulation of protein localization to nucleus GO:1900181 2 0.017
regulation of signaling GO:0023051 235 0.017
cell cell junction organization GO:0045216 10 0.017
regulation of protein targeting GO:1903533 2 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
response to organic substance GO:0010033 153 0.017
regulation of molecular function GO:0065009 70 0.017
growth GO:0040007 174 0.017
autophagy GO:0006914 4 0.017
protein acetylation GO:0006473 2 0.017
heterocycle metabolic process GO:0046483 290 0.017
regulation of jak stat cascade GO:0046425 3 0.017
regulation of sodium ion transport GO:0002028 2 0.016
regulation of localization GO:0032879 104 0.016
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.016
apoptotic process GO:0006915 116 0.016
stem cell proliferation GO:0072089 4 0.016
alcohol biosynthetic process GO:0046165 2 0.016
regulation of protein catabolic process GO:0042176 1 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
regulation of epidermis development GO:0045682 2 0.016
regulation of cell projection assembly GO:0060491 4 0.016
single organism transport GO:0044765 206 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
somitogenesis GO:0001756 87 0.015
regulation of catalytic activity GO:0050790 55 0.015
ion homeostasis GO:0050801 41 0.015
anterior posterior pattern specification GO:0009952 152 0.015
transcription dna templated GO:0006351 181 0.015
multicellular organism growth GO:0035264 4 0.015
nitrogen compound metabolic process GO:0006807 319 0.015
notochord development GO:0030903 54 0.015
negative regulation of cytokine production GO:0001818 1 0.015
organelle organization GO:0006996 227 0.015
energy reserve metabolic process GO:0006112 2 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
response to hexose GO:0009746 3 0.014
camera type eye development GO:0043010 222 0.014
cell substrate junction assembly GO:0007044 2 0.014
regulation of chromosome segregation GO:0051983 1 0.014
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.014
positive regulation of biological process GO:0048518 253 0.014
ras protein signal transduction GO:0007265 7 0.014
cell migration GO:0016477 237 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
positive regulation of cytokine production GO:0001819 2 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
skin development GO:0043588 54 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.013
positive regulation of molecular function GO:0044093 33 0.013
single organism metabolic process GO:0044710 217 0.013
system process GO:0003008 185 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
wnt signaling pathway GO:0016055 80 0.013
adherens junction assembly GO:0034333 1 0.013
phosphorus metabolic process GO:0006793 109 0.013
ear development GO:0043583 127 0.013
tissue remodeling GO:0048771 4 0.013
notch signaling pathway GO:0007219 35 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
negative regulation of protein import into nucleus GO:0042308 2 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
positive regulation of signaling GO:0023056 56 0.013
nucleic acid templated transcription GO:0097659 181 0.013
rna biosynthetic process GO:0032774 181 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of endocrine process GO:0044060 2 0.012
regulation of blood vessel size GO:0050880 2 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
regulation of gene expression GO:0010468 265 0.012
cell projection morphogenesis GO:0048858 244 0.012
post golgi vesicle mediated transport GO:0006892 1 0.012
double strand break repair GO:0006302 3 0.012
epithelial cell differentiation GO:0030855 116 0.012
nucleic acid metabolic process GO:0090304 244 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
head development GO:0060322 303 0.012
response to monosaccharide GO:0034284 3 0.012
primary neural tube formation GO:0014020 1 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
transmembrane transport GO:0055085 120 0.012
tube morphogenesis GO:0035239 349 0.012
establishment of localization in cell GO:0051649 77 0.012
programmed cell death GO:0012501 119 0.012
regulation of transcription dna templated GO:0006355 213 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
bone remodeling GO:0046849 2 0.012
negative regulation of catabolic process GO:0009895 3 0.012
cellular response to nutrient GO:0031670 1 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
fat soluble vitamin metabolic process GO:0006775 4 0.012
regulation of cell activation GO:0050865 1 0.012
leukocyte proliferation GO:0070661 1 0.012
sodium ion transport GO:0006814 24 0.012
negative regulation of cell communication GO:0010648 96 0.011
neuromast development GO:0048884 46 0.011
regulation of ras gtpase activity GO:0032318 2 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
macromolecular complex disassembly GO:0032984 1 0.011
regulation of embryonic development GO:0045995 47 0.011
neuroblast proliferation GO:0007405 2 0.011
single organism organelle organization GO:1902589 199 0.011
retinoid metabolic process GO:0001523 15 0.011
cellular response to oxygen levels GO:0071453 1 0.011
sensory system development GO:0048880 76 0.011
rna metabolic process GO:0016070 219 0.011
regulation of cell shape GO:0008360 1 0.011
cell death GO:0008219 121 0.011
tube closure GO:0060606 1 0.011
b cell activation GO:0042113 2 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
cellular response to starvation GO:0009267 1 0.011
epiboly GO:0090504 41 0.011
small molecule catabolic process GO:0044282 3 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
regulation of response to stimulus GO:0048583 269 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
cartilage development GO:0051216 96 0.011
regulation of bone remodeling GO:0046850 2 0.011
neuron differentiation GO:0030182 353 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
cytokinetic process GO:0032506 2 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
interspecies interaction between organisms GO:0044419 4 0.011
single organism cell adhesion GO:0098602 29 0.011
negative regulation of metabolic process GO:0009892 86 0.011
protein complex disassembly GO:0043241 1 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.010
cellular response to hormone stimulus GO:0032870 39 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
cellular component assembly GO:0022607 170 0.010
mitochondrion organization GO:0007005 4 0.010
developmental growth involved in morphogenesis GO:0060560 86 0.010
regulation of cell morphogenesis GO:0022604 42 0.010
embryonic organ development GO:0048568 381 0.010
regulation of protein binding GO:0043393 3 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
epidermal cell differentiation GO:0009913 36 0.010

sb:eu854 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.061
musculoskeletal system disease DOID:17 0 0.046
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.013
connective tissue disease DOID:65 0 0.012
bone disease DOID:0080001 0 0.012