Danio rerio

0 known processes

mkln1

muskelin 1, intracellular mediator containing kelch motifs

(Aliases: wu:fc60a07,fc60a07)

mkln1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing compound metabolic process GO:0006139 274 0.154
signal transduction GO:0007165 455 0.152
organic cyclic compound metabolic process GO:1901360 301 0.131
nitrogen compound metabolic process GO:0006807 319 0.122
rna metabolic process GO:0016070 219 0.097
cellular aromatic compound metabolic process GO:0006725 295 0.094
organic substance biosynthetic process GO:1901576 289 0.093
heterocycle metabolic process GO:0046483 290 0.091
ubiquitin dependent protein catabolic process GO:0006511 3 0.090
neuron differentiation GO:0030182 353 0.087
regulation of cellular metabolic process GO:0031323 320 0.085
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.083
cell surface receptor signaling pathway GO:0007166 325 0.082
regulation of primary metabolic process GO:0080090 311 0.079
modification dependent macromolecule catabolic process GO:0043632 3 0.077
nucleobase containing compound biosynthetic process GO:0034654 205 0.073
heterocycle biosynthetic process GO:0018130 215 0.070
modification dependent protein catabolic process GO:0019941 3 0.064
cellular protein catabolic process GO:0044257 4 0.061
cellular nitrogen compound biosynthetic process GO:0044271 218 0.061
brain development GO:0007420 293 0.059
nucleic acid templated transcription GO:0097659 181 0.057
macromolecule biosynthetic process GO:0009059 227 0.057
regulation of protein transport GO:0051223 3 0.056
regulation of metabolic process GO:0019222 359 0.056
regulation of nucleic acid templated transcription GO:1903506 213 0.053
regulation of transcription dna templated GO:0006355 213 0.053
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.053
organic cyclic compound biosynthetic process GO:1901362 223 0.050
establishment of protein localization to organelle GO:0072594 4 0.050
positive regulation of cellular catabolic process GO:0031331 3 0.049
aging GO:0007568 2 0.048
protein localization to nucleus GO:0034504 3 0.048
maintenance of location GO:0051235 4 0.047
regulation of rna biosynthetic process GO:2001141 213 0.046
cellular macromolecule metabolic process GO:0044260 391 0.045
regulation of signaling GO:0023051 235 0.044
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.043
regulation of protein catabolic process GO:0042176 1 0.043
regulation of establishment of protein localization GO:0070201 4 0.041
gtp catabolic process GO:0006184 2 0.041
aromatic compound biosynthetic process GO:0019438 217 0.040
cellular macromolecule biosynthetic process GO:0034645 224 0.040
proteasomal protein catabolic process GO:0010498 2 0.039
negative regulation of protein transport GO:0051224 3 0.038
lipid storage GO:0019915 1 0.037
cellular nitrogen compound metabolic process GO:0034641 290 0.036
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.036
regulation of biosynthetic process GO:0009889 250 0.035
regulation of rna metabolic process GO:0051252 224 0.034
guanosine containing compound catabolic process GO:1901069 2 0.034
biosynthetic process GO:0009058 294 0.033
cell part morphogenesis GO:0032990 246 0.033
nuclear import GO:0051170 3 0.033
phosphorus metabolic process GO:0006793 109 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.032
nucleic acid metabolic process GO:0090304 244 0.031
positive regulation of transport GO:0051050 2 0.031
regulation of cell communication GO:0010646 232 0.030
cell cycle g1 s phase transition GO:0044843 1 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.030
regulation of nitrogen compound metabolic process GO:0051171 251 0.029
single organism metabolic process GO:0044710 217 0.029
protein import into nucleus GO:0006606 3 0.029
negative regulation of catabolic process GO:0009895 3 0.029
negative regulation of protein import into nucleus GO:0042308 2 0.028
positive regulation of catabolic process GO:0009896 4 0.028
peptide transport GO:0015833 1 0.028
transcription dna templated GO:0006351 181 0.028
regulation of gene expression GO:0010468 265 0.027
protein import GO:0017038 3 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
meiotic cell cycle process GO:1903046 3 0.025
rna biosynthetic process GO:0032774 181 0.024
phosphate containing compound metabolic process GO:0006796 108 0.024
axonogenesis GO:0007409 152 0.024
erk1 and erk2 cascade GO:0070371 4 0.024
regulation of signal transduction GO:0009966 225 0.024
cellular biosynthetic process GO:0044249 286 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
negative regulation of protein localization to nucleus GO:1900181 2 0.023
gene expression GO:0010467 252 0.023
regulation of cell development GO:0060284 100 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
single organism membrane fusion GO:0044801 2 0.023
single organism nuclear import GO:1902593 3 0.023
regulation of localization GO:0032879 104 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
centrosome organization GO:0051297 1 0.022
centrosome cycle GO:0007098 1 0.022
neuron development GO:0048666 262 0.021
protein polyubiquitination GO:0000209 4 0.021
negative regulation of biological process GO:0048519 304 0.021
establishment of localization GO:0051234 244 0.021
blood vessel morphogenesis GO:0048514 216 0.021
membrane fusion GO:0061025 2 0.021
forebrain cell migration GO:0021885 1 0.021
protein metabolic process GO:0019538 183 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
positive regulation of gtp catabolic process GO:0033126 1 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.020
single organism transport GO:0044765 206 0.020
negative regulation of cytoplasmic transport GO:1903650 2 0.019
cell cycle process GO:0022402 53 0.019
negative regulation of mapk cascade GO:0043409 4 0.019
cognition GO:0050890 1 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
negative regulation of reproductive process GO:2000242 3 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
single organism localization GO:1902578 225 0.019
negative regulation of intracellular protein transport GO:0090317 3 0.019
vasculature development GO:0001944 278 0.019
enzyme linked receptor protein signaling pathway GO:0007167 106 0.018
nuclear transport GO:0051169 4 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
carbohydrate homeostasis GO:0033500 1 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
transport GO:0006810 220 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
cytokinesis GO:0000910 3 0.017
cell projection morphogenesis GO:0048858 244 0.016
gtp metabolic process GO:0046039 4 0.016
organelle organization GO:0006996 227 0.016
generation of neurons GO:0048699 385 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
small gtpase mediated signal transduction GO:0007264 8 0.016
regulation of reproductive process GO:2000241 4 0.016
cell projection organization GO:0030030 284 0.016
endosomal transport GO:0016197 2 0.016
regulation of metal ion transport GO:0010959 4 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
neurological system process GO:0050877 62 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
autophagy GO:0006914 4 0.015
blood vessel development GO:0001568 246 0.015
regulation of circadian rhythm GO:0042752 4 0.015
protein stabilization GO:0050821 2 0.015
positive regulation of gtpase activity GO:0043547 1 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
regulation of erk1 and erk2 cascade GO:0070372 4 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
central nervous system development GO:0007417 387 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
response to stress GO:0006950 263 0.014
signal transduction by p53 class mediator GO:0072331 13 0.014
exocytosis GO:0006887 1 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
regulation of cell death GO:0010941 103 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
sex determination GO:0007530 1 0.014
cellular component assembly GO:0022607 170 0.014
protein dephosphorylation GO:0006470 3 0.014
cell migration GO:0016477 237 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
positive regulation of cell division GO:0051781 2 0.014
regulation of multicellular organismal development GO:2000026 223 0.013
positive regulation of metabolic process GO:0009893 108 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
homeostatic process GO:0042592 142 0.013
microtubule organizing center organization GO:0031023 1 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
regulation of programmed cell death GO:0043067 101 0.013
digestive system development GO:0055123 289 0.013
regulation of protein targeting GO:1903533 2 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
protein modification process GO:0036211 100 0.013
meiotic nuclear division GO:0007126 4 0.013
macromolecule modification GO:0043412 111 0.013
regulation of gtpase activity GO:0043087 2 0.013
ras protein signal transduction GO:0007265 7 0.013
positive regulation of exocytosis GO:0045921 1 0.013
cellular response to oxygen levels GO:0071453 1 0.012
single organism organelle organization GO:1902589 199 0.012
sensory organ development GO:0007423 393 0.012
neuron projection morphogenesis GO:0048812 161 0.012
cellular response to hypoxia GO:0071456 1 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
cellular modified amino acid metabolic process GO:0006575 3 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
developmental programmed cell death GO:0010623 4 0.012
cellular component morphogenesis GO:0032989 336 0.012
cellular protein metabolic process GO:0044267 129 0.012
regulation of biological quality GO:0065008 263 0.012
cellular amine metabolic process GO:0044106 2 0.012
rho protein signal transduction GO:0007266 5 0.011
regulation of response to stimulus GO:0048583 269 0.011
hormone secretion GO:0046879 2 0.011
response to chemical GO:0042221 320 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
regulation of ras gtpase activity GO:0032318 2 0.011
axon development GO:0061564 166 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
rna localization GO:0006403 4 0.011
organelle fusion GO:0048284 3 0.011
small molecule metabolic process GO:0044281 77 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
growth GO:0040007 174 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
cytoplasm organization GO:0007028 4 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
leukocyte homeostasis GO:0001776 2 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
chemosensory behavior GO:0007635 1 0.011
cellular catabolic process GO:0044248 27 0.011
regulation of nervous system development GO:0051960 90 0.011
positive regulation of signal transduction GO:0009967 56 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
centrosome localization GO:0051642 1 0.010
regulation of multicellular organism growth GO:0040014 4 0.010
golgi vesicle transport GO:0048193 3 0.010
synaptic vesicle transport GO:0048489 1 0.010
compound eye development GO:0048749 2 0.010
establishment of localization in cell GO:0051649 77 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
phosphorylation GO:0016310 69 0.010
cellular respiration GO:0045333 3 0.010
negative regulation of gene expression GO:0010629 65 0.010

mkln1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011