Danio rerio

0 known processes

zgc:77456

zgc:77456

(Aliases: MGC77456,lhfpl2)

zgc:77456 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 3 0.175
regulation of cellular metabolic process GO:0031323 320 0.154
negative regulation of biological process GO:0048519 304 0.151
regulation of signaling GO:0023051 235 0.148
regulation of signal transduction GO:0009966 225 0.146
regulation of mrna processing GO:0050684 3 0.129
regulation of metabolic process GO:0019222 359 0.122
regulation of response to stimulus GO:0048583 269 0.107
specification of symmetry GO:0009799 204 0.107
cytokinesis GO:0000910 3 0.095
heart development GO:0007507 313 0.093
cellular protein metabolic process GO:0044267 129 0.083
fertilization GO:0009566 3 0.082
stem cell maintenance GO:0019827 4 0.081
organelle organization GO:0006996 227 0.078
response to stress GO:0006950 263 0.072
vasculature development GO:0001944 278 0.072
larval development GO:0002164 2 0.071
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.070
blood vessel development GO:0001568 246 0.070
system process GO:0003008 185 0.066
single organism membrane fusion GO:0044801 2 0.064
single fertilization GO:0007338 3 0.057
gene expression GO:0010467 252 0.056
nucleocytoplasmic transport GO:0006913 4 0.054
signal transduction GO:0007165 455 0.053
transmission of nerve impulse GO:0019226 19 0.052
nuclear transport GO:0051169 4 0.052
regulation of protein catabolic process GO:0042176 1 0.050
negative regulation of macromolecule metabolic process GO:0010605 76 0.049
modification dependent protein catabolic process GO:0019941 3 0.048
regulation of metal ion transport GO:0010959 4 0.048
regulation of synapse organization GO:0050807 3 0.047
cellular macromolecule biosynthetic process GO:0034645 224 0.046
synaptic growth at neuromuscular junction GO:0051124 2 0.045
regulation of primary metabolic process GO:0080090 311 0.045
cellular protein catabolic process GO:0044257 4 0.044
ubiquitin dependent protein catabolic process GO:0006511 3 0.044
regulation of meiotic cell cycle GO:0051445 1 0.044
cellular component morphogenesis GO:0032989 336 0.043
regulation of cell communication GO:0010646 232 0.043
nuclear migration GO:0007097 3 0.043
cellular ketone metabolic process GO:0042180 11 0.043
death GO:0016265 121 0.043
regulation of intracellular protein transport GO:0033157 3 0.043
determination of left right symmetry GO:0007368 179 0.043
cell morphogenesis GO:0000902 289 0.042
meiotic cell cycle process GO:1903046 3 0.041
cytoskeleton dependent cytokinesis GO:0061640 3 0.041
positive regulation of apoptotic signaling pathway GO:2001235 1 0.041
organic substance biosynthetic process GO:1901576 289 0.041
locomotion GO:0040011 313 0.040
amine metabolic process GO:0009308 2 0.040
neuron development GO:0048666 262 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.040
aging GO:0007568 2 0.039
regulation of cellular amine metabolic process GO:0033238 0 0.039
single organism organelle organization GO:1902589 199 0.038
regulation of reproductive process GO:2000241 4 0.037
single organism metabolic process GO:0044710 217 0.037
embryo development ending in birth or egg hatching GO:0009792 271 0.037
peptidyl threonine modification GO:0018210 1 0.037
intracellular signal transduction GO:0035556 85 0.036
lateral inhibition GO:0046331 1 0.036
regulation of gene expression GO:0010468 265 0.035
nitrogen compound metabolic process GO:0006807 319 0.034
taxis GO:0042330 109 0.034
regulation of anatomical structure morphogenesis GO:0022603 130 0.034
proteasomal protein catabolic process GO:0010498 2 0.033
small gtpase mediated signal transduction GO:0007264 8 0.033
establishment of protein localization to organelle GO:0072594 4 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.032
negative regulation of protein kinase activity GO:0006469 4 0.032
positive regulation of stress activated mapk cascade GO:0032874 3 0.032
blood vessel morphogenesis GO:0048514 216 0.032
peptidyl threonine phosphorylation GO:0018107 1 0.031
neuroblast proliferation GO:0007405 2 0.031
meiotic nuclear division GO:0007126 4 0.030
regulation of synapse assembly GO:0051963 3 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
embryonic heart tube development GO:0035050 133 0.030
stem cell proliferation GO:0072089 4 0.030
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.030
guanosine containing compound catabolic process GO:1901069 2 0.029
microtubule based process GO:0007017 60 0.029
establishment of localization GO:0051234 244 0.029
phagocytosis GO:0006909 3 0.029
regulation of multicellular organism growth GO:0040014 4 0.029
macromolecule biosynthetic process GO:0009059 227 0.028
protein localization to plasma membrane GO:0072659 1 0.028
positive regulation of transport GO:0051050 2 0.028
negative regulation of chromosome organization GO:2001251 1 0.028
multicellular organism growth GO:0035264 4 0.028
regulation of stem cell differentiation GO:2000736 4 0.027
negative regulation of cellular process GO:0048523 283 0.027
phosphorus metabolic process GO:0006793 109 0.026
regulation of developmental process GO:0050793 247 0.026
adherens junction maintenance GO:0034334 2 0.026
protein acetylation GO:0006473 2 0.025
protein targeting to nucleus GO:0044744 3 0.025
maintenance of location GO:0051235 4 0.025
cell death GO:0008219 121 0.025
embryonic organ morphogenesis GO:0048562 274 0.025
multi organism process GO:0051704 134 0.025
lipid storage GO:0019915 1 0.025
cellular lipid catabolic process GO:0044242 3 0.025
hematopoietic or lymphoid organ development GO:0048534 191 0.024
aromatic compound biosynthetic process GO:0019438 217 0.024
cell migration GO:0016477 237 0.024
multicellular organismal signaling GO:0035637 22 0.024
cell part morphogenesis GO:0032990 246 0.024
regulation of biological quality GO:0065008 263 0.023
protein localization to nucleus GO:0034504 3 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
mitotic cell cycle GO:0000278 64 0.023
cellular response to stress GO:0033554 62 0.023
mitotic cytokinesis GO:0000281 3 0.022
response to abiotic stimulus GO:0009628 122 0.022
regulation of cellular protein catabolic process GO:1903362 1 0.022
medulla oblongata development GO:0021550 4 0.022
regulation of mrna splicing via spliceosome GO:0048024 3 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
cognition GO:0050890 1 0.022
positive regulation of cell cycle GO:0045787 3 0.022
regulation of p38mapk cascade GO:1900744 1 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.021
cellular macromolecule metabolic process GO:0044260 391 0.021
regulation of cell development GO:0060284 100 0.021
apoptotic process GO:0006915 116 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
positive regulation of cellular process GO:0048522 201 0.021
organelle fusion GO:0048284 3 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
positive regulation of dna metabolic process GO:0051054 1 0.021
oocyte maturation GO:0001556 4 0.021
adherens junction organization GO:0034332 4 0.021
cell projection organization GO:0030030 284 0.021
cellular component biogenesis GO:0044085 178 0.021
eye development GO:0001654 277 0.021
gtp catabolic process GO:0006184 2 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.020
protein metabolic process GO:0019538 183 0.020
cell projection morphogenesis GO:0048858 244 0.020
regulation of cellular component organization GO:0051128 86 0.020
developmental growth GO:0048589 166 0.020
myelination GO:0042552 18 0.019
ras protein signal transduction GO:0007265 7 0.019
immune system process GO:0002376 241 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
regulation of biosynthetic process GO:0009889 250 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
determination of bilateral symmetry GO:0009855 204 0.019
negative regulation of mapk cascade GO:0043409 4 0.019
negative regulation of cellular catabolic process GO:0031330 3 0.019
organic acid metabolic process GO:0006082 31 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
cellular amine metabolic process GO:0044106 2 0.019
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.018
membrane fusion GO:0061025 2 0.018
regulation of apoptotic process GO:0042981 98 0.018
regulation of cellular response to growth factor stimulus GO:0090287 35 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
cell cycle GO:0007049 93 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.018
positive regulation of signal transduction GO:0009967 56 0.018
neurological system process GO:0050877 62 0.018
response to external stimulus GO:0009605 264 0.018
peptidyl serine phosphorylation GO:0018105 1 0.018
pronuclear migration GO:0035046 1 0.017
telomere maintenance GO:0000723 1 0.017
positive regulation of metabolic process GO:0009893 108 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
programmed cell death GO:0012501 119 0.017
alcohol biosynthetic process GO:0046165 2 0.017
neuron projection development GO:0031175 180 0.017
cell junction maintenance GO:0034331 2 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
immune system development GO:0002520 191 0.017
response to chemical GO:0042221 320 0.017
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
neuronal action potential GO:0019228 18 0.016
gastrulation GO:0007369 208 0.016
heart looping GO:0001947 94 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
pharyngeal muscle development GO:0043282 4 0.016
alternative mrna splicing via spliceosome GO:0000380 1 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
cell cycle process GO:0022402 53 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
growth GO:0040007 174 0.016
lamellipodium assembly GO:0030032 1 0.016
peptidyl serine modification GO:0018209 2 0.016
regulation of oocyte development GO:0060281 3 0.016
regulation of chromosome segregation GO:0051983 1 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
regulation of sodium ion transport GO:0002028 2 0.016
nucleic acid metabolic process GO:0090304 244 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
regulation of intracellular signal transduction GO:1902531 57 0.016
cellular component maintenance GO:0043954 3 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
chordate embryonic development GO:0043009 271 0.015
spermatid development GO:0007286 2 0.015
fatty acid catabolic process GO:0009062 1 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
embryonic organ development GO:0048568 381 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
single organism biosynthetic process GO:0044711 71 0.015
oxoacid metabolic process GO:0043436 31 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
regulation of cell shape GO:0008360 1 0.015
digestive system development GO:0055123 289 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
small molecule metabolic process GO:0044281 77 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
positive regulation of catabolic process GO:0009896 4 0.015
regulation of protein transport GO:0051223 3 0.015
erythrocyte differentiation GO:0030218 54 0.014
negative regulation of synapse assembly GO:0051964 2 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
cellular macromolecule catabolic process GO:0044265 12 0.014
regulation of rna metabolic process GO:0051252 224 0.014
hemopoiesis GO:0030097 183 0.014
mesoderm development GO:0007498 88 0.014
tube morphogenesis GO:0035239 349 0.014
regulation of programmed cell death GO:0043067 101 0.014
single organism transport GO:0044765 206 0.014
inner ear receptor cell fate commitment GO:0060120 4 0.014
muscle structure development GO:0061061 196 0.014
protein modification process GO:0036211 100 0.013
cranial nerve development GO:0021545 42 0.013
gliogenesis GO:0042063 45 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
positive regulation of oocyte development GO:0060282 1 0.013
primitive hemopoiesis GO:0060215 27 0.013
regulation of inflammatory response GO:0050727 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
glial cell differentiation GO:0010001 42 0.013
negative regulation of kinase activity GO:0033673 4 0.013
gtp metabolic process GO:0046039 4 0.013
protein import GO:0017038 3 0.013
microtubule organizing center organization GO:0031023 1 0.013
positive regulation of signaling GO:0023056 56 0.013
transcription dna templated GO:0006351 181 0.013
organelle assembly GO:0070925 110 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
regulation of binding GO:0051098 3 0.013
cranial nerve morphogenesis GO:0021602 15 0.013
epithelial tube morphogenesis GO:0060562 148 0.012
rna 3 end processing GO:0031123 2 0.012
positive regulation of synapse assembly GO:0051965 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
regulation of catalytic activity GO:0050790 55 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
negative regulation of mitosis GO:0045839 3 0.012
epithelium regeneration GO:1990399 14 0.012
erythrocyte homeostasis GO:0034101 55 0.012
protein stabilization GO:0050821 2 0.012
eye morphogenesis GO:0048592 144 0.012
negative regulation of metabolic process GO:0009892 86 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
organelle localization GO:0051640 49 0.012
digestive tract mesoderm development GO:0007502 1 0.012
small molecule catabolic process GO:0044282 3 0.012
spermatid differentiation GO:0048515 2 0.012
determination of ventral identity GO:0048264 21 0.012
meiosis i GO:0007127 1 0.012
peptide transport GO:0015833 1 0.012
cellular biosynthetic process GO:0044249 286 0.012
mechanosensory behavior GO:0007638 2 0.012
negative regulation of dna metabolic process GO:0051053 4 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.011
regulation of protein complex assembly GO:0043254 3 0.011
phagocytosis engulfment GO:0006911 1 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
membrane invagination GO:0010324 1 0.011
positive regulation of reproductive process GO:2000243 2 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
negative regulation of reproductive process GO:2000242 3 0.011
hormone secretion GO:0046879 2 0.011
regulation of mitochondrion organization GO:0010821 1 0.011
transport GO:0006810 220 0.011
leukocyte proliferation GO:0070661 1 0.011
mapk cascade GO:0000165 18 0.011
regulation of cell death GO:0010941 103 0.011
nuclear import GO:0051170 3 0.011
cellular response to dna damage stimulus GO:0006974 24 0.011
heart morphogenesis GO:0003007 156 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
germ line stem cell maintenance GO:0030718 2 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
regulation of gtpase activity GO:0043087 2 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
epithelial cell morphogenesis GO:0003382 2 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
actin cytoskeleton organization GO:0030036 63 0.010
cellular macromolecular complex assembly GO:0034622 24 0.010
neuron differentiation GO:0030182 353 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
negative regulation of signal transduction GO:0009968 94 0.010
neuron projection morphogenesis GO:0048812 161 0.010
negative regulation of rna splicing GO:0033119 1 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
regulation of mrna 3 end processing GO:0031440 1 0.010
regulation of lipid transport GO:0032368 4 0.010
cellular response to external stimulus GO:0071496 2 0.010
central nervous system development GO:0007417 387 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010

zgc:77456 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
cardiovascular system disease DOID:1287 0 0.018