Danio rerio

0 known processes

parn

poly(A)-specific ribonuclease (deadenylation nuclease)

(Aliases: MGC56067,zgc:56067)

parn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
biosynthetic process GO:0009058 294 0.209
larval development GO:0002164 2 0.199
regulation of rna biosynthetic process GO:2001141 213 0.164
modification dependent protein catabolic process GO:0019941 3 0.154
heterocycle biosynthetic process GO:0018130 215 0.131
regulation of transcription dna templated GO:0006355 213 0.130
regulation of response to stimulus GO:0048583 269 0.127
rna biosynthetic process GO:0032774 181 0.122
macromolecule biosynthetic process GO:0009059 227 0.109
regulation of metabolic process GO:0019222 359 0.109
regulation of macromolecule metabolic process GO:0060255 317 0.108
regulation of biosynthetic process GO:0009889 250 0.107
cellular protein catabolic process GO:0044257 4 0.107
cellular biosynthetic process GO:0044249 286 0.105
regulation of cellular metabolic process GO:0031323 320 0.101
nucleic acid templated transcription GO:0097659 181 0.092
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.089
nucleic acid metabolic process GO:0090304 244 0.085
rna metabolic process GO:0016070 219 0.081
negative regulation of biological process GO:0048519 304 0.081
transcription dna templated GO:0006351 181 0.080
regulation of rna metabolic process GO:0051252 224 0.080
ubiquitin dependent protein catabolic process GO:0006511 3 0.079
cellular nitrogen compound biosynthetic process GO:0044271 218 0.078
aromatic compound biosynthetic process GO:0019438 217 0.077
regulation of cell communication GO:0010646 232 0.075
regulation of gene expression GO:0010468 265 0.075
gene expression GO:0010467 252 0.074
positive regulation of transport GO:0051050 2 0.073
locomotion GO:0040011 313 0.073
modification dependent macromolecule catabolic process GO:0043632 3 0.072
protein localization to nucleus GO:0034504 3 0.069
regulation of primary metabolic process GO:0080090 311 0.069
organic substance biosynthetic process GO:1901576 289 0.068
signal transduction GO:0007165 455 0.068
negative regulation of cellular process GO:0048523 283 0.066
regulation of cellular biosynthetic process GO:0031326 245 0.065
regulation of macromolecule biosynthetic process GO:0010556 225 0.064
cellular protein modification process GO:0006464 100 0.064
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.064
nucleobase containing compound metabolic process GO:0006139 274 0.063
cellular aromatic compound metabolic process GO:0006725 295 0.060
cell projection morphogenesis GO:0048858 244 0.058
cellular response to external stimulus GO:0071496 2 0.058
organic cyclic compound biosynthetic process GO:1901362 223 0.056
cellular nitrogen compound metabolic process GO:0034641 290 0.056
cellular macromolecule metabolic process GO:0044260 391 0.055
generation of neurons GO:0048699 385 0.055
organelle organization GO:0006996 227 0.054
single organism metabolic process GO:0044710 217 0.054
maintenance of location GO:0051235 4 0.054
cell surface receptor signaling pathway GO:0007166 325 0.053
embryo development ending in birth or egg hatching GO:0009792 271 0.053
regulation of establishment of protein localization GO:0070201 4 0.052
regulation of nucleic acid templated transcription GO:1903506 213 0.051
cell morphogenesis GO:0000902 289 0.049
cellular protein metabolic process GO:0044267 129 0.049
cell projection organization GO:0030030 284 0.049
positive regulation of biological process GO:0048518 253 0.049
cellular component morphogenesis GO:0032989 336 0.049
regulation of signal transduction GO:0009966 225 0.048
regulation of nitrogen compound metabolic process GO:0051171 251 0.048
cell morphogenesis involved in differentiation GO:0000904 195 0.048
nucleobase containing compound biosynthetic process GO:0034654 205 0.046
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.045
neuron development GO:0048666 262 0.045
cellular response to chemical stimulus GO:0070887 157 0.044
phagocytosis GO:0006909 3 0.044
cellular macromolecule biosynthetic process GO:0034645 224 0.044
organic cyclic compound metabolic process GO:1901360 301 0.044
protein metabolic process GO:0019538 183 0.043
heterocycle metabolic process GO:0046483 290 0.043
stem cell maintenance GO:0019827 4 0.042
neuron projection morphogenesis GO:0048812 161 0.041
regulation of multicellular organism growth GO:0040014 4 0.041
neuron differentiation GO:0030182 353 0.040
nitrogen compound metabolic process GO:0006807 319 0.040
regulation of signaling GO:0023051 235 0.040
intracellular signal transduction GO:0035556 85 0.039
vasculature development GO:0001944 278 0.039
nucleus organization GO:0006997 7 0.038
positive regulation of cellular metabolic process GO:0031325 94 0.038
microtubule organizing center organization GO:0031023 1 0.037
regulation of protein transport GO:0051223 3 0.037
protein modification process GO:0036211 100 0.037
neuron projection development GO:0031175 180 0.035
cell migration GO:0016477 237 0.034
cellular response to nutrient levels GO:0031669 2 0.034
regulation of cellular component organization GO:0051128 86 0.034
cell death GO:0008219 121 0.034
protein targeting to nucleus GO:0044744 3 0.033
proteasomal protein catabolic process GO:0010498 2 0.033
negative regulation of metabolic process GO:0009892 86 0.033
multi organism process GO:0051704 134 0.033
regulation of multicellular organismal development GO:2000026 223 0.033
positive regulation of macromolecule metabolic process GO:0010604 93 0.033
regulation of synapse organization GO:0050807 3 0.032
response to chemical GO:0042221 320 0.032
female gonad development GO:0008585 4 0.032
nuclear transport GO:0051169 4 0.032
regulation of protein localization to nucleus GO:1900180 2 0.031
stem cell proliferation GO:0072089 4 0.031
aging GO:0007568 2 0.030
single organism organelle organization GO:1902589 199 0.030
regulation of protein import into nucleus GO:0042306 2 0.030
macromolecule modification GO:0043412 111 0.030
transcription from rna polymerase ii promoter GO:0006366 80 0.030
regulation of developmental process GO:0050793 247 0.030
cell part morphogenesis GO:0032990 246 0.029
response to stress GO:0006950 263 0.029
regulation of cytoplasmic transport GO:1903649 4 0.029
lipid storage GO:0019915 1 0.029
protein import GO:0017038 3 0.028
negative regulation of signal transduction GO:0009968 94 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
nuclear import GO:0051170 3 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
single organism nuclear import GO:1902593 3 0.028
cellular response to extracellular stimulus GO:0031668 2 0.028
multicellular organism growth GO:0035264 4 0.027
regulation of reproductive process GO:2000241 4 0.027
regulation of cell differentiation GO:0045595 142 0.027
positive regulation of rna biosynthetic process GO:1902680 57 0.027
wnt signaling pathway GO:0016055 80 0.027
transport GO:0006810 220 0.026
development of primary female sexual characteristics GO:0046545 4 0.026
protein dephosphorylation GO:0006470 3 0.026
regulation of biological quality GO:0065008 263 0.026
cellular component movement GO:0006928 335 0.026
female sex differentiation GO:0046660 4 0.025
autophagy GO:0006914 4 0.025
response to external stimulus GO:0009605 264 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
central nervous system development GO:0007417 387 0.025
regionalization GO:0003002 274 0.025
neuroblast proliferation GO:0007405 2 0.025
positive regulation of map kinase activity GO:0043406 3 0.025
negative regulation of response to stimulus GO:0048585 104 0.025
cognition GO:0050890 1 0.025
cellular component disassembly GO:0022411 1 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.024
positive regulation of biosynthetic process GO:0009891 68 0.024
negative regulation of cell communication GO:0010648 96 0.024
negative regulation of macromolecule metabolic process GO:0010605 76 0.024
protein polyubiquitination GO:0000209 4 0.024
regulation of erk1 and erk2 cascade GO:0070372 4 0.023
cytokinesis GO:0000910 3 0.023
regulation of programmed cell death GO:0043067 101 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
digestive system development GO:0055123 289 0.023
protein k48 linked ubiquitination GO:0070936 1 0.023
positive regulation of cellular process GO:0048522 201 0.023
negative regulation of catabolic process GO:0009895 3 0.023
response to nutrient GO:0007584 3 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
axonogenesis GO:0007409 152 0.022
regulation of intracellular protein transport GO:0033157 3 0.022
regulation of wnt signaling pathway GO:0030111 53 0.022
protein import into nucleus GO:0006606 3 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.022
single organism localization GO:1902578 225 0.022
negative regulation of multicellular organismal process GO:0051241 69 0.022
regulation of synapse assembly GO:0051963 3 0.021
digestive tract development GO:0048565 265 0.021
protein complex disassembly GO:0043241 1 0.021
positive regulation of cellular biosynthetic process GO:0031328 68 0.021
regulation of chromosome segregation GO:0051983 1 0.021
positive regulation of jun kinase activity GO:0043507 2 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
positive regulation of rna metabolic process GO:0051254 59 0.021
cellular component biogenesis GO:0044085 178 0.021
blood vessel morphogenesis GO:0048514 216 0.021
negative regulation of gene expression GO:0010629 65 0.021
amine metabolic process GO:0009308 2 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.020
centrosome organization GO:0051297 1 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
positive regulation of metabolic process GO:0009893 108 0.020
system process GO:0003008 185 0.020
cellular amine metabolic process GO:0044106 2 0.020
sensory organ development GO:0007423 393 0.020
blood vessel development GO:0001568 246 0.020
cellular response to starvation GO:0009267 1 0.020
localization of cell GO:0051674 244 0.020
muscle organ development GO:0007517 101 0.020
ameboidal type cell migration GO:0001667 143 0.020
tissue remodeling GO:0048771 4 0.019
nuclear envelope organization GO:0006998 2 0.019
regulation of response to nutrient levels GO:0032107 1 0.019
death GO:0016265 121 0.019
regulation of protein targeting GO:1903533 2 0.019
adult behavior GO:0030534 2 0.019
negative regulation of signaling GO:0023057 96 0.019
positive regulation of response to stimulus GO:0048584 80 0.019
regulation of establishment of planar polarity GO:0090175 4 0.019
cellular response to organic substance GO:0071310 105 0.019
stem cell division GO:0017145 1 0.019
regulation of microtubule cytoskeleton organization GO:0070507 3 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.018
synaptic target recognition GO:0008039 1 0.018
angiogenesis GO:0001525 158 0.018
cellular ketone metabolic process GO:0042180 11 0.018
positive regulation of signal transduction GO:0009967 56 0.018
meiotic nuclear division GO:0007126 4 0.018
chemotaxis GO:0006935 104 0.018
macromolecular complex disassembly GO:0032984 1 0.018
regulation of cell activation GO:0050865 1 0.018
regulation of dna templated transcription elongation GO:0032784 3 0.018
regulation of localization GO:0032879 104 0.018
centrosome cycle GO:0007098 1 0.017
negative regulation of transcription dna templated GO:0045892 45 0.017
chemosensory behavior GO:0007635 1 0.017
immune system process GO:0002376 241 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
protein polymerization GO:0051258 4 0.017
dna templated transcription elongation GO:0006354 3 0.017
heart development GO:0007507 313 0.017
spindle assembly GO:0051225 2 0.017
regulation of response to extracellular stimulus GO:0032104 1 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.017
positive regulation of secretion GO:0051047 1 0.017
positive regulation of cell communication GO:0010647 56 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
somatic stem cell maintenance GO:0035019 1 0.017
positive regulation of immune effector process GO:0002699 3 0.017
negative regulation of developmental process GO:0051093 65 0.017
canonical wnt signaling pathway GO:0060070 48 0.017
regulation of protein complex assembly GO:0043254 3 0.017
peptide transport GO:0015833 1 0.016
positive regulation of signaling GO:0023056 56 0.016
cell substrate adhesion GO:0031589 4 0.016
negative regulation of reproductive process GO:2000242 3 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
regulation of cytokine production GO:0001817 3 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.016
taxis GO:0042330 109 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
protein acetylation GO:0006473 2 0.016
cellular response to biotic stimulus GO:0071216 3 0.016
regulation of jak stat cascade GO:0046425 3 0.016
cellular component assembly GO:0022607 170 0.016
regulation of neural precursor cell proliferation GO:2000177 3 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
negative regulation of mapk cascade GO:0043409 4 0.015
positive regulation of muscle organ development GO:0048636 1 0.015
proteolysis GO:0006508 38 0.015
axon development GO:0061564 166 0.015
head development GO:0060322 303 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
programmed cell death GO:0012501 119 0.015
forebrain regionalization GO:0021871 4 0.015
regulation of circadian rhythm GO:0042752 4 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
negative regulation of biosynthetic process GO:0009890 55 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
establishment of localization GO:0051234 244 0.015
negative regulation of cell differentiation GO:0045596 46 0.015
histone modification GO:0016570 20 0.015
positive regulation of transcription dna templated GO:0045893 57 0.015
lateral inhibition GO:0046331 1 0.015
regulation of protein metabolic process GO:0051246 56 0.015
cell motility GO:0048870 244 0.015
centrosome duplication GO:0051298 1 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
response to hexose GO:0009746 3 0.014
macroautophagy GO:0016236 1 0.014
double strand break repair GO:0006302 3 0.014
endosomal transport GO:0016197 2 0.014
anterior posterior pattern specification GO:0009952 152 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
hemopoiesis GO:0030097 183 0.014
regulation of autophagy GO:0010506 3 0.014
cell cycle process GO:0022402 53 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
developmental growth GO:0048589 166 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
chromosome organization GO:0051276 31 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
negative regulation of kinase activity GO:0033673 4 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
cell aging GO:0007569 2 0.014
neuron projection extension GO:1990138 45 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
response to drug GO:0042493 3 0.013
positive regulation of protein kinase b signaling GO:0051897 1 0.013
chordate embryonic development GO:0043009 271 0.013
cell cycle arrest GO:0007050 1 0.013
regulation of cellular component movement GO:0051270 55 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
positive regulation of nucleic acid templated transcription GO:1903508 57 0.013
protein acylation GO:0043543 3 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
brain development GO:0007420 293 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
positive regulation of striated muscle tissue development GO:0045844 1 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
positive regulation of catabolic process GO:0009896 4 0.013
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.013
locomotor rhythm GO:0045475 3 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
g2 dna damage checkpoint GO:0031572 3 0.013
membrane invagination GO:0010324 1 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
mesenchyme development GO:0060485 127 0.013
regulation of binding GO:0051098 3 0.013
stem cell differentiation GO:0048863 117 0.012
regulation of translational initiation GO:0006446 1 0.012
positive regulation of cell activation GO:0050867 1 0.012
positive regulation of leukocyte mediated immunity GO:0002705 1 0.012
positive regulation of histone modification GO:0031058 1 0.012
protein secretion GO:0009306 1 0.012
cell cycle GO:0007049 93 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
regulation of cell death GO:0010941 103 0.012
connective tissue development GO:0061448 99 0.012
regulation of blood pressure GO:0008217 1 0.012
negative regulation of protein transport GO:0051224 3 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
phosphorus metabolic process GO:0006793 109 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
response to organic substance GO:0010033 153 0.012
regulation of response to stress GO:0080134 36 0.012
olfactory bulb development GO:0021772 4 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
response to biotic stimulus GO:0009607 97 0.012
tube morphogenesis GO:0035239 349 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
regulation of canonical wnt signaling pathway GO:0060828 34 0.012
response to endogenous stimulus GO:0009719 83 0.012
positive regulation of gene expression GO:0010628 71 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
negative regulation of multi organism process GO:0043901 3 0.012
cellular amide metabolic process GO:0043603 4 0.012
regulation of apoptotic process GO:0042981 98 0.012
negative chemotaxis GO:0050919 1 0.012
chromatin organization GO:0006325 22 0.012
morphogenesis of an epithelium GO:0002009 333 0.011
cartilage development GO:0051216 96 0.011
mitotic cell cycle process GO:1903047 48 0.011
organism emergence from protective structure GO:0071684 4 0.011
regulation of cell motility GO:2000145 46 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
positive regulation of cell cycle GO:0045787 3 0.011
single organism transport GO:0044765 206 0.011
regulation of cell cycle GO:0051726 52 0.011
negative regulation of protein import into nucleus GO:0042308 2 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
neuron remodeling GO:0016322 1 0.011
negative regulation of neural precursor cell proliferation GO:2000178 1 0.011
cell matrix adhesion GO:0007160 4 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
immune system development GO:0002520 191 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
gland development GO:0048732 143 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
eye development GO:0001654 277 0.011
peptidyl serine modification GO:0018209 2 0.011
mrna polyadenylation GO:0006378 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
polarized epithelial cell differentiation GO:0030859 4 0.011
regulation of nervous system development GO:0051960 90 0.011
regulation of inflammatory response GO:0050727 2 0.011
skeletal system development GO:0001501 181 0.011
hormone transport GO:0009914 2 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
glial cell proliferation GO:0014009 4 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
cellular response to stress GO:0033554 62 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
reproduction GO:0000003 40 0.011
response to monosaccharide GO:0034284 3 0.011
carbohydrate homeostasis GO:0033500 1 0.011
response to corticosteroid GO:0031960 1 0.011
negative regulation of defense response GO:0031348 2 0.011
activation of mapk activity GO:0000187 3 0.010
phosphorylation GO:0016310 69 0.010
reproductive process GO:0022414 40 0.010
septum transversum development GO:0003343 4 0.010
developmental programmed cell death GO:0010623 4 0.010
organic acid metabolic process GO:0006082 31 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010
hormone secretion GO:0046879 2 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
embryonic organ development GO:0048568 381 0.010
regulation of locomotion GO:0040012 55 0.010
muscle structure development GO:0061061 196 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
apoptotic process involved in development GO:1902742 2 0.010
negative regulation of cytokine production GO:0001818 1 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010

parn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.014