Danio rerio

67 known processes

syk

spleen tyrosine kinase

syk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.194
regulation of biological quality GO:0065008 263 0.173
Mouse Fly
regulation of developmental process GO:0050793 247 0.134
negative regulation of cellular process GO:0048523 283 0.119
negative regulation of biological process GO:0048519 304 0.112
cognition GO:0050890 1 0.107
aromatic compound biosynthetic process GO:0019438 217 0.107
Human
regionalization GO:0003002 274 0.103
multicellular organism growth GO:0035264 4 0.100
nucleobase containing compound metabolic process GO:0006139 274 0.085
Human
regulation of multicellular organism growth GO:0040014 4 0.078
rna metabolic process GO:0016070 219 0.074
Human
positive regulation of cellular component biogenesis GO:0044089 3 0.073
regulation of synapse organization GO:0050807 3 0.073
regulation of macromolecule metabolic process GO:0060255 317 0.071
Human Mouse
regulation of gene expression GO:0010468 265 0.068
Human
regulation of cell differentiation GO:0045595 142 0.068
Mouse
heterocycle metabolic process GO:0046483 290 0.068
Human
stem cell maintenance GO:0019827 4 0.066
aging GO:0007568 2 0.065
positive regulation of cell cycle GO:0045787 3 0.065
regulation of cell shape GO:0008360 1 0.063
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.060
Human
signal transduction GO:0007165 455 0.060
Mouse Fly
cellular biosynthetic process GO:0044249 286 0.059
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.058
Human
morphogenesis of an epithelium GO:0002009 333 0.056
Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.056
gastrulation GO:0007369 208 0.055
regulation of signaling GO:0023051 235 0.055
Mouse
anterior posterior pattern specification GO:0009952 152 0.053
sensory organ development GO:0007423 393 0.053
synaptic growth at neuromuscular junction GO:0051124 2 0.052
immune system development GO:0002520 191 0.052
Mouse
convergent extension GO:0060026 118 0.051
regulation of cytokine production GO:0001817 3 0.051
Mouse
cellular modified amino acid metabolic process GO:0006575 3 0.050
nitrogen compound metabolic process GO:0006807 319 0.050
Human
organic cyclic compound metabolic process GO:1901360 301 0.050
Human
regulation of primary metabolic process GO:0080090 311 0.049
Human Mouse
organic substance biosynthetic process GO:1901576 289 0.049
Human Mouse
regulation of cell activation GO:0050865 1 0.048
Mouse Rat
maintenance of location GO:0051235 4 0.048
positive regulation of transport GO:0051050 2 0.047
Mouse Rat
synaptic transmission cholinergic GO:0007271 4 0.047
cellular aromatic compound metabolic process GO:0006725 295 0.047
Human
nucleic acid templated transcription GO:0097659 181 0.046
Human
regulation of metabolic process GO:0019222 359 0.046
Human Mouse
cellular component morphogenesis GO:0032989 336 0.046
Fly
macromolecule biosynthetic process GO:0009059 227 0.046
Human Mouse
cellular macromolecule metabolic process GO:0044260 391 0.045
Human Mouse Rat
response to chemical GO:0042221 320 0.045
Human Mouse
gene expression GO:0010467 252 0.045
Human
response to carbohydrate GO:0009743 3 0.044
leukocyte proliferation GO:0070661 1 0.044
Mouse
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.043
regulation of wound healing GO:0061041 2 0.043
Mouse
tube morphogenesis GO:0035239 349 0.043
positive regulation of map kinase activity GO:0043406 3 0.042
Mouse
phagocytosis GO:0006909 3 0.042
Mouse Fly
system process GO:0003008 185 0.042
regulation of protein complex assembly GO:0043254 3 0.041
spermatid development GO:0007286 2 0.041
cellular nitrogen compound biosynthetic process GO:0044271 218 0.041
Human
response to drug GO:0042493 3 0.041
positive regulation of protein complex assembly GO:0031334 2 0.040
response to stress GO:0006950 263 0.040
Mouse Fly
regulation of dna replication GO:0006275 3 0.039
regulation of receptor activity GO:0010469 2 0.039
modification dependent protein catabolic process GO:0019941 3 0.039
negative regulation of cellular catabolic process GO:0031330 3 0.039
b cell activation GO:0042113 2 0.039
Mouse
regulation of biosynthetic process GO:0009889 250 0.039
Human Mouse
lipid storage GO:0019915 1 0.038
negative regulation of myeloid cell differentiation GO:0045638 1 0.038
digestive system development GO:0055123 289 0.037
cytokinesis GO:0000910 3 0.037
developmental growth GO:0048589 166 0.036
Fly
b cell differentiation GO:0030183 1 0.036
Mouse
pole plasm assembly GO:0007315 4 0.036
mononuclear cell proliferation GO:0032943 1 0.036
Mouse
gland development GO:0048732 143 0.035
regulation of autophagy GO:0010506 3 0.035
nucleic acid metabolic process GO:0090304 244 0.035
Human
regulation of cellular biosynthetic process GO:0031326 245 0.035
Human Mouse
generation of neurons GO:0048699 385 0.035
Fly
regulation of signal transduction GO:0009966 225 0.035
Mouse
regulation of embryonic development GO:0045995 47 0.035
Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.034
ubiquitin dependent protein catabolic process GO:0006511 3 0.034
regulation of rna biosynthetic process GO:2001141 213 0.034
Human
regulation of protein ubiquitination GO:0031396 3 0.034
regulation of cellular amino acid metabolic process GO:0006521 0 0.034
regulation of stem cell differentiation GO:2000736 4 0.034
regulation of multicellular organismal process GO:0051239 277 0.033
hematopoietic or lymphoid organ development GO:0048534 191 0.033
Mouse
digestive tract morphogenesis GO:0048546 231 0.033
negative regulation of protein phosphorylation GO:0001933 4 0.033
organic acid metabolic process GO:0006082 31 0.033
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.033
regulation of cellular ketone metabolic process GO:0010565 7 0.033
regulation of nitrogen compound metabolic process GO:0051171 251 0.033
Human
regulation of cell projection assembly GO:0060491 4 0.033
digestive tract development GO:0048565 265 0.033
growth GO:0040007 174 0.032
Fly
protein localization to nucleus GO:0034504 3 0.032
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.032
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.032
Mouse
biosynthetic process GO:0009058 294 0.032
Human Mouse
intracellular signal transduction GO:0035556 85 0.031
Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.031
Human
cell projection organization GO:0030030 284 0.031
Fly
female sex differentiation GO:0046660 4 0.031
cellular response to lipopolysaccharide GO:0071222 3 0.031
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.031
vasculature development GO:0001944 278 0.031
negative regulation of cytokine production GO:0001818 1 0.031
rna localization GO:0006403 4 0.031
enzyme linked receptor protein signaling pathway GO:0007167 106 0.031
Mouse
regulation of multicellular organismal development GO:2000026 223 0.031
regulation of cellular metabolic process GO:0031323 320 0.031
Human Mouse
carboxylic acid metabolic process GO:0019752 22 0.030
Mouse
regulation of transcription dna templated GO:0006355 213 0.030
Human
sensory perception of chemical stimulus GO:0007606 3 0.030
oxoacid metabolic process GO:0043436 31 0.029
Mouse
immune system process GO:0002376 241 0.029
Human Mouse Rat
cellular amino acid metabolic process GO:0006520 7 0.029
tissue remodeling GO:0048771 4 0.029
Mouse
response to wounding GO:0009611 116 0.029
Mouse
negative regulation of catabolic process GO:0009895 3 0.029
cellular macromolecule biosynthetic process GO:0034645 224 0.029
Human
protein heterooligomerization GO:0051291 1 0.029
cell projection morphogenesis GO:0048858 244 0.028
Fly
single organism localization GO:1902578 225 0.028
Human Mouse Rat Fly
regulation of synaptic plasticity GO:0048167 1 0.028
convergent extension involved in gastrulation GO:0060027 71 0.028
protein metabolic process GO:0019538 183 0.028
Human Mouse Rat
alpha amino acid metabolic process GO:1901605 3 0.028
cellular response to external stimulus GO:0071496 2 0.028
brain development GO:0007420 293 0.027
spermatid differentiation GO:0048515 2 0.027
locomotor rhythm GO:0045475 3 0.027
single organism transport GO:0044765 206 0.027
Human Mouse Rat Fly
somitogenesis GO:0001756 87 0.027
negative regulation of protein kinase activity GO:0006469 4 0.027
adult behavior GO:0030534 2 0.027
somatic muscle development GO:0007525 4 0.027
regulation of apoptotic process GO:0042981 98 0.027
stem cell proliferation GO:0072089 4 0.027
wnt signaling pathway GO:0016055 80 0.027
positive regulation of biological process GO:0048518 253 0.027
transcription dna templated GO:0006351 181 0.027
Human
heart development GO:0007507 313 0.027
homeostatic process GO:0042592 142 0.027
Mouse
negative regulation of signaling GO:0023057 96 0.026
stem cell division GO:0017145 1 0.026
hepaticobiliary system development GO:0061008 98 0.026
positive regulation of cell adhesion GO:0045785 1 0.026
Mouse
cellular component movement GO:0006928 335 0.026
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.026
response to external stimulus GO:0009605 264 0.025
Human Mouse
cellular component assembly GO:0022607 170 0.025
amine metabolic process GO:0009308 2 0.025
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
Human Mouse
lymphocyte proliferation GO:0046651 1 0.025
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.025
stem cell differentiation GO:0048863 117 0.025
cell cycle GO:0007049 93 0.025
blood vessel development GO:0001568 246 0.025
regulation of reproductive process GO:2000241 4 0.025
cell motility GO:0048870 244 0.025
cellular ketone metabolic process GO:0042180 11 0.025
oocyte maturation GO:0001556 4 0.025
regulation of jak stat cascade GO:0046425 3 0.024
cell morphogenesis GO:0000902 289 0.024
Fly
chordate embryonic development GO:0043009 271 0.024
striated muscle tissue development GO:0014706 110 0.024
positive regulation of striated muscle cell differentiation GO:0051155 1 0.024
regulation of cell communication GO:0010646 232 0.024
Mouse
sensory system development GO:0048880 76 0.024
regulation of protein transport GO:0051223 3 0.024
Mouse
female gonad development GO:0008585 4 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
Mouse
localization of cell GO:0051674 244 0.024
neuron projection morphogenesis GO:0048812 161 0.024
Fly
chemosensory behavior GO:0007635 1 0.024
signal transduction in absence of ligand GO:0038034 1 0.024
leukocyte homeostasis GO:0001776 2 0.024
nucleocytoplasmic transport GO:0006913 4 0.024
Human
regulation of synapse assembly GO:0051963 3 0.024
positive regulation of cellular biosynthetic process GO:0031328 68 0.023
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.023
Human
phagocytosis engulfment GO:0006911 1 0.023
positive regulation of dna metabolic process GO:0051054 1 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
intracellular mrna localization GO:0008298 1 0.023
regulation of binding GO:0051098 3 0.023
transport GO:0006810 220 0.023
Human Mouse Rat Fly
muscle structure development GO:0061061 196 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
compound eye development GO:0048749 2 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
Human
maternal determination of anterior posterior axis embryo GO:0008358 4 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
cell cycle arrest GO:0007050 1 0.023
cytoskeleton dependent cytokinesis GO:0061640 3 0.023
actin polymerization or depolymerization GO:0008154 2 0.023
cellular protein modification process GO:0006464 100 0.023
Human Mouse Rat
zymogen activation GO:0031638 3 0.023
positive regulation of cell activation GO:0050867 1 0.023
Mouse Rat
regulation of oocyte development GO:0060281 3 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
negative regulation of multicellular organismal process GO:0051241 69 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
regulation of organelle assembly GO:1902115 4 0.022
cell part morphogenesis GO:0032990 246 0.022
Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.022
antimicrobial humoral response GO:0019730 2 0.022
regulation of protein localization to nucleus GO:1900180 2 0.022
protein polymerization GO:0051258 4 0.022
regulation of cell death GO:0010941 103 0.022
ribosome assembly GO:0042255 1 0.022
response to biotic stimulus GO:0009607 97 0.022
Mouse
astrocyte differentiation GO:0048708 1 0.022
germ line stem cell maintenance GO:0030718 2 0.022
eye development GO:0001654 277 0.022
liver development GO:0001889 96 0.021
regulation of response to nutrient levels GO:0032107 1 0.021
microtubule organizing center organization GO:0031023 1 0.021
cilium morphogenesis GO:0060271 85 0.021
cytoplasm organization GO:0007028 4 0.021
positive regulation of secretion by cell GO:1903532 1 0.021
Mouse Rat
endosomal transport GO:0016197 2 0.021
embryonic heart tube development GO:0035050 133 0.021
developmental programmed cell death GO:0010623 4 0.021
erk1 and erk2 cascade GO:0070371 4 0.021
Mouse
segmentation GO:0035282 97 0.021
regulation of wnt signaling pathway GO:0030111 53 0.021
regulation of dendrite development GO:0050773 3 0.021
positive regulation of translation GO:0045727 1 0.021
negative regulation of wnt signaling pathway GO:0030178 30 0.021
positive regulation of cellular process GO:0048522 201 0.021
cellular amine metabolic process GO:0044106 2 0.021
single organism organelle organization GO:1902589 199 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
cellular protein catabolic process GO:0044257 4 0.020
positive regulation of myeloid cell differentiation GO:0045639 2 0.020
membrane fusion GO:0061025 2 0.020
nuclear transport GO:0051169 4 0.020
Human
positive regulation of gene expression GO:0010628 71 0.020
cell death GO:0008219 121 0.020
regulation of epithelial cell proliferation GO:0050678 3 0.020
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.020
response to corticosteroid GO:0031960 1 0.020
actin filament based movement GO:0030048 1 0.020
head development GO:0060322 303 0.020
central nervous system development GO:0007417 387 0.020
protein import into nucleus GO:0006606 3 0.020
Human
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
regulation of protein binding GO:0043393 3 0.019
ectodermal placode development GO:0071696 37 0.019
single organism metabolic process GO:0044710 217 0.019
Mouse Fly
somite development GO:0061053 96 0.019
macromolecular complex disassembly GO:0032984 1 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
sex determination GO:0007530 1 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
regulation of blood vessel size GO:0050880 2 0.019
negative regulation of developmental process GO:0051093 65 0.019
positive regulation of neuron apoptotic process GO:0043525 1 0.019
regulation of erythrocyte differentiation GO:0045646 2 0.019
somatic stem cell maintenance GO:0035019 1 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.019
regulation of glial cell differentiation GO:0045685 4 0.019
regulation of response to extracellular stimulus GO:0032104 1 0.019
cellular component biogenesis GO:0044085 178 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
negative regulation of nuclear division GO:0051784 3 0.019
neuron development GO:0048666 262 0.019
Fly
cellular response to oxygen levels GO:0071453 1 0.019
single organism nuclear import GO:1902593 3 0.019
Human
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
locomotion GO:0040011 313 0.019
blood vessel morphogenesis GO:0048514 216 0.019
gtp metabolic process GO:0046039 4 0.018
gtp catabolic process GO:0006184 2 0.018
tyrosine phosphorylation of stat protein GO:0007260 1 0.018
positive regulation of neuron death GO:1901216 1 0.018
response to monosaccharide GO:0034284 3 0.018
hepatocyte differentiation GO:0070365 1 0.018
determination of left right symmetry GO:0007368 179 0.018
protein import GO:0017038 3 0.018
Human
ameboidal type cell migration GO:0001667 143 0.018
regulation of erk1 and erk2 cascade GO:0070372 4 0.018
Mouse
guanosine containing compound metabolic process GO:1901068 4 0.018
positive regulation of cytokine production GO:0001819 2 0.018
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.018
exocytosis GO:0006887 1 0.018
Mouse Rat
positive regulation of apoptotic signaling pathway GO:2001235 1 0.018
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.018
synaptic vesicle transport GO:0048489 1 0.018
negative regulation of cell communication GO:0010648 96 0.018
periodic partitioning GO:0007365 1 0.018
stem cell development GO:0048864 82 0.018
regulation of glucose import GO:0046324 1 0.018
cardiac atrium development GO:0003230 4 0.018
epithelial cell morphogenesis GO:0003382 2 0.018
negative regulation of synapse assembly GO:0051964 2 0.018
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.017
autophagy GO:0006914 4 0.017
peptidyl threonine modification GO:0018210 1 0.017
centrosome organization GO:0051297 1 0.017
positive regulation of catabolic process GO:0009896 4 0.017
cellular component disassembly GO:0022411 1 0.017
muscle cell migration GO:0014812 4 0.017
protein complex disassembly GO:0043241 1 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
positive regulation of multicellular organismal process GO:0051240 52 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
negative regulation of leukocyte differentiation GO:1902106 1 0.017
positive regulation of secretion GO:0051047 1 0.017
Mouse Rat
cellular response to radiation GO:0071478 4 0.017
cilium or flagellum dependent cell motility GO:0001539 4 0.017
embryonic organ development GO:0048568 381 0.017
post embryonic organ development GO:0048569 4 0.017
post embryonic morphogenesis GO:0009886 4 0.017
regulation of blood pressure GO:0008217 1 0.017
positive regulation of developmental process GO:0051094 50 0.017
negative regulation of kinase activity GO:0033673 4 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.017
meiotic nuclear division GO:0007126 4 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
gastrulation with mouth forming second GO:0001702 44 0.017
circulatory system process GO:0003013 87 0.017
multi organism process GO:0051704 134 0.017
Mouse Fly
neuron remodeling GO:0016322 1 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
canonical wnt signaling pathway GO:0060070 48 0.017
regulation of organ growth GO:0046620 3 0.016
lamellipodium organization GO:0097581 1 0.016
membrane invagination GO:0010324 1 0.016
adherens junction organization GO:0034332 4 0.016
regulation of carbohydrate metabolic process GO:0006109 4 0.016
carbohydrate homeostasis GO:0033500 1 0.016
regulation of localization GO:0032879 104 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
negative regulation of biosynthetic process GO:0009890 55 0.016
positive regulation of muscle cell differentiation GO:0051149 1 0.016
neuron neuron synaptic transmission GO:0007270 1 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
Fly
determination of heart left right asymmetry GO:0061371 117 0.016
hemopoiesis GO:0030097 183 0.016
Mouse
cellular carbohydrate metabolic process GO:0044262 4 0.016
apoptotic process GO:0006915 116 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.016
muscle organ development GO:0007517 101 0.016
regulation of protein targeting GO:1903533 2 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
cellular response to retinoic acid GO:0071300 1 0.016
protein depolymerization GO:0051261 1 0.016
cellular response to organic substance GO:0071310 105 0.016
oocyte anterior posterior axis specification GO:0007314 4 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
positive regulation of metabolic process GO:0009893 108 0.015
Mouse
regulation of canonical wnt signaling pathway GO:0060828 34 0.015
inner ear development GO:0048839 126 0.015
response to endogenous stimulus GO:0009719 83 0.015
organelle organization GO:0006996 227 0.015
single organism membrane fusion GO:0044801 2 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
axonogenesis GO:0007409 152 0.015
regulation of tube size GO:0035150 2 0.015
cellular response to hormone stimulus GO:0032870 39 0.015
regulation of protein catabolic process GO:0042176 1 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
cellular protein metabolic process GO:0044267 129 0.015
Human Mouse Rat
cartilage development GO:0051216 96 0.015
peptidyl serine modification GO:0018209 2 0.015
Mouse
blood circulation GO:0008015 87 0.015
response to organic substance GO:0010033 153 0.015
Mouse
dorsal convergence GO:0060030 14 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
Mouse
positive regulation of cytoskeleton organization GO:0051495 3 0.015
nuclear import GO:0051170 3 0.015
Human
small molecule metabolic process GO:0044281 77 0.015
Mouse
embryonic digestive tract development GO:0048566 4 0.015
protein modification process GO:0036211 100 0.015
Human Mouse Rat
regulation of programmed cell death GO:0043067 101 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
cellular response to nutrient levels GO:0031669 2 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
response to virus GO:0009615 21 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
camera type eye development GO:0043010 222 0.014
meiotic cell cycle process GO:1903046 3 0.014
response to glucocorticoid GO:0051384 1 0.014
protein acetylation GO:0006473 2 0.014
dna templated transcription initiation GO:0006352 1 0.014
positive regulation of wound healing GO:0090303 1 0.014
negative regulation of map kinase activity GO:0043407 2 0.014
determination of bilateral symmetry GO:0009855 204 0.014
positive regulation of rna metabolic process GO:0051254 59 0.014
glucose homeostasis GO:0042593 1 0.014
regulation of exocytosis GO:0017157 1 0.014
Mouse Rat
ion homeostasis GO:0050801 41 0.014
cell substrate junction assembly GO:0007044 2 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
establishment of localization GO:0051234 244 0.014
Human Mouse Rat Fly
organonitrogen compound metabolic process GO:1901564 74 0.014
homeostasis of number of cells GO:0048872 62 0.014
response to other organism GO:0051707 97 0.014
Mouse
glucose import GO:0046323 2 0.014
positive regulation of rna biosynthetic process GO:1902680 57 0.014
embryonic pattern specification GO:0009880 44 0.014
regulation of metal ion transport GO:0010959 4 0.014
negative regulation of metabolic process GO:0009892 86 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
double strand break repair GO:0006302 3 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
wound healing GO:0042060 90 0.013
Mouse
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
cellular response to stress GO:0033554 62 0.013
Mouse Fly
cellular response to starvation GO:0009267 1 0.013
mitotic cytokinesis GO:0000281 3 0.013
response to hexose GO:0009746 3 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
macromolecule modification GO:0043412 111 0.013
Human Mouse Rat
mitotic cell cycle process GO:1903047 48 0.013
positive regulation of cell killing GO:0031343 2 0.013
erythrocyte homeostasis GO:0034101 55 0.013
cellular amide metabolic process GO:0043603 4 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
Mouse
cellular response to decreased oxygen levels GO:0036294 1 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
Human Mouse Rat Fly
establishment of synaptic vesicle localization GO:0097480 1 0.013
response to bacterium GO:0009617 58 0.013
Mouse
negative regulation of dna metabolic process GO:0051053 4 0.013
neuron differentiation GO:0030182 353 0.013
Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
regulation of myotube differentiation GO:0010830 2 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
regulation of locomotion GO:0040012 55 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
epithelial cell differentiation GO:0030855 116 0.013
Fly
tube closure GO:0060606 1 0.013
protein acylation GO:0043543 3 0.013
regulation of hormone secretion GO:0046883 2 0.013
protein targeting to nucleus GO:0044744 3 0.013
Human
negative regulation of gastrulation GO:2000542 11 0.013
directional locomotion GO:0033058 1 0.013
erythrocyte differentiation GO:0030218 54 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
connective tissue development GO:0061448 99 0.013
negative regulation of mitosis GO:0045839 3 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
positive regulation of protein kinase b signaling GO:0051897 1 0.013
cardiac atrium morphogenesis GO:0003209 2 0.013
glial cell migration GO:0008347 3 0.012
branched chain amino acid metabolic process GO:0009081 1 0.012
cell fate commitment GO:0045165 99 0.012
peptidyl threonine phosphorylation GO:0018107 1 0.012
nucleic acid transport GO:0050657 2 0.012
interaction with host GO:0051701 4 0.012
heart looping GO:0001947 94 0.012
central nervous system myelination GO:0022010 2 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
Fly
protein stabilization GO:0050821 2 0.012
glial cell differentiation GO:0010001 42 0.012
cortical cytoskeleton organization GO:0030865 1 0.012
skeletal muscle organ development GO:0060538 78 0.012
hormone transport GO:0009914 2 0.012
axon development GO:0061564 166 0.012
protein homooligomerization GO:0051260 3 0.012
mitotic cell cycle GO:0000278 64 0.012

syk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
cancer DOID:162 0 0.028
disease of cellular proliferation DOID:14566 0 0.028
disease of metabolism DOID:0014667 0 0.023
organ system cancer DOID:0050686 0 0.022
nervous system disease DOID:863 0 0.022
immune system disease DOID:2914 0 0.020
aplastic anemia DOID:12449 0 0.016
bone marrow disease DOID:4961 0 0.016
anemia DOID:2355 0 0.016
hematopoietic system disease DOID:74 0 0.016
bone development disease DOID:0080006 0 0.015
bone disease DOID:0080001 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
muscular disease DOID:0080000 0 0.013