Danio rerio

23 known processes

vdac2

voltage-dependent anion channel 2

(Aliases: zgc:55795,wu:fa98a10,wu:fa01a08,wu:fb50g11,zgc:77621)

vdac2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism localization GO:1902578 225 0.294
larval development GO:0002164 2 0.179
establishment of localization GO:0051234 244 0.160
transport GO:0006810 220 0.142
embryo development ending in birth or egg hatching GO:0009792 271 0.122
aging GO:0007568 2 0.116
single organism transport GO:0044765 206 0.116
gene expression GO:0010467 252 0.110
regulation of reactive oxygen species metabolic process GO:2000377 2 0.104
nitrogen compound metabolic process GO:0006807 319 0.100
heart development GO:0007507 313 0.098
cellular component assembly GO:0022607 170 0.085
phagocytosis GO:0006909 3 0.082
regulation of cell shape GO:0008360 1 0.078
cellular biosynthetic process GO:0044249 286 0.073
reproductive process GO:0022414 40 0.070
Fly
sensory organ development GO:0007423 393 0.068
negative regulation of biological process GO:0048519 304 0.062
muscle cell differentiation GO:0042692 139 0.057
organic cyclic compound biosynthetic process GO:1901362 223 0.057
heterocycle metabolic process GO:0046483 290 0.056
regulation of wound healing GO:0061041 2 0.055
purine ribonucleotide biosynthetic process GO:0009152 20 0.053
organelle organization GO:0006996 227 0.053
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.049
striated muscle cell development GO:0055002 108 0.049
response to transition metal nanoparticle GO:1990267 28 0.046
regulation of metabolic process GO:0019222 359 0.044
nucleobase containing compound biosynthetic process GO:0034654 205 0.042
positive regulation of wound healing GO:0090303 1 0.042
regulation of developmental process GO:0050793 247 0.042
oxidative phosphorylation GO:0006119 1 0.041
organonitrogen compound metabolic process GO:1901564 74 0.041
multi organism process GO:0051704 134 0.040
Fly
centrosome organization GO:0051297 1 0.040
response to drug GO:0042493 3 0.040
cellular aromatic compound metabolic process GO:0006725 295 0.039
muscle structure development GO:0061061 196 0.039
single organism organelle organization GO:1902589 199 0.037
single fertilization GO:0007338 3 0.037
nucleobase containing compound metabolic process GO:0006139 274 0.037
muscle cell development GO:0055001 115 0.036
multicellular organism growth GO:0035264 4 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.035
neuromast development GO:0048884 46 0.035
establishment of protein localization to organelle GO:0072594 4 0.034
regulation of biological quality GO:0065008 263 0.034
microtubule organizing center organization GO:0031023 1 0.033
organic substance biosynthetic process GO:1901576 289 0.033
sexual reproduction GO:0019953 36 0.032
Fly
cellular transition metal ion homeostasis GO:0046916 3 0.031
negative regulation of cellular process GO:0048523 283 0.030
muscle organ development GO:0007517 101 0.029
apoptotic process GO:0006915 116 0.029
embryonic organ development GO:0048568 381 0.029
regulation of mrna processing GO:0050684 3 0.028
striated muscle cell differentiation GO:0051146 129 0.028
nucleoside phosphate biosynthetic process GO:1901293 21 0.028
nuclear transport GO:0051169 4 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
protein secretion GO:0009306 1 0.027
gtp metabolic process GO:0046039 4 0.027
meiotic nuclear division GO:0007126 4 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
myofibril assembly GO:0030239 48 0.026
small molecule metabolic process GO:0044281 77 0.026
sensory organ morphogenesis GO:0090596 200 0.026
multi organism reproductive process GO:0044703 36 0.026
Fly
regulation of reproductive process GO:2000241 4 0.026
embryonic organ morphogenesis GO:0048562 274 0.026
response to metal ion GO:0010038 34 0.026
positive regulation of transport GO:0051050 2 0.025
extrinsic apoptotic signaling pathway GO:0097191 3 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
purine containing compound biosynthetic process GO:0072522 20 0.025
maintenance of location GO:0051235 4 0.024
nuclear migration GO:0007097 3 0.024
inner ear development GO:0048839 126 0.024
nucleoside biosynthetic process GO:0009163 2 0.024
signal transduction in absence of ligand GO:0038034 1 0.024
response to cadmium ion GO:0046686 14 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
purine nucleoside monophosphate catabolic process GO:0009128 4 0.024
adherens junction organization GO:0034332 4 0.024
cellular component assembly involved in morphogenesis GO:0010927 107 0.024
organic cyclic compound metabolic process GO:1901360 301 0.023
lipid storage GO:0019915 1 0.023
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
response to stress GO:0006950 263 0.023
regulation of binding GO:0051098 3 0.023
regulation of stem cell differentiation GO:2000736 4 0.023
head development GO:0060322 303 0.023
aromatic compound biosynthetic process GO:0019438 217 0.022
transmembrane transport GO:0055085 120 0.022
amine metabolic process GO:0009308 2 0.022
regulation of programmed cell death GO:0043067 101 0.022
regulation of cell communication GO:0010646 232 0.022
protein localization to nucleus GO:0034504 3 0.022
purine ribonucleoside biosynthetic process GO:0046129 2 0.022
developmental process involved in reproduction GO:0003006 27 0.022
Fly
dorsal ventral pattern formation GO:0009953 125 0.022
cellular component movement GO:0006928 335 0.022
cellular amine metabolic process GO:0044106 2 0.022
ear development GO:0043583 127 0.021
ion transmembrane transport GO:0034220 91 0.021
Fly
carbohydrate derivative metabolic process GO:1901135 61 0.021
eye development GO:0001654 277 0.021
fin development GO:0033333 77 0.021
actin filament based process GO:0030029 64 0.021
cellular component morphogenesis GO:0032989 336 0.021
localization of cell GO:0051674 244 0.021
protein targeting to membrane GO:0006612 1 0.020
protein complex assembly GO:0006461 30 0.020
mesenchyme development GO:0060485 127 0.020
cytokinesis GO:0000910 3 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.020
cranial nerve development GO:0021545 42 0.020
spindle assembly involved in mitosis GO:0090307 1 0.020
regulation of apoptotic process GO:0042981 98 0.020
regulation of primary metabolic process GO:0080090 311 0.020
regulation of cell death GO:0010941 103 0.020
regulation of cell activation GO:0050865 1 0.020
endocardial cushion morphogenesis GO:0003203 3 0.020
regulation of protein transport GO:0051223 3 0.020
organonitrogen compound biosynthetic process GO:1901566 47 0.020
protein import GO:0017038 3 0.019
translational initiation GO:0006413 3 0.019
cellular amide metabolic process GO:0043603 4 0.019
phosphorylation GO:0016310 69 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
negative regulation of catabolic process GO:0009895 3 0.019
cell death GO:0008219 121 0.019
protein polymerization GO:0051258 4 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
response to chemical GO:0042221 320 0.019
cellular protein metabolic process GO:0044267 129 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.018
biosynthetic process GO:0009058 294 0.018
centrosome cycle GO:0007098 1 0.018
response to nutrient GO:0007584 3 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
cellular component biogenesis GO:0044085 178 0.018
cell motility GO:0048870 244 0.018
regulation of protein binding GO:0043393 3 0.018
neuron differentiation GO:0030182 353 0.018
macromolecule modification GO:0043412 111 0.018
protein stabilization GO:0050821 2 0.018
regulation of blood vessel size GO:0050880 2 0.018
stem cell maintenance GO:0019827 4 0.018
mitochondrial transport GO:0006839 2 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
organelle assembly GO:0070925 110 0.017
muscle tissue development GO:0060537 110 0.017
regulation of gene expression GO:0010468 265 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
heart morphogenesis GO:0003007 156 0.017
carbohydrate derivative biosynthetic process GO:1901137 43 0.017
regulation of response to stress GO:0080134 36 0.017
somitogenesis GO:0001756 87 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
negative regulation of metabolic process GO:0009892 86 0.017
wound healing GO:0042060 90 0.017
regulation of protein metabolic process GO:0051246 56 0.017
rna localization GO:0006403 4 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.017
phosphorus metabolic process GO:0006793 109 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
system process GO:0003008 185 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
rna metabolic process GO:0016070 219 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
macromolecular complex assembly GO:0065003 35 0.016
regulation of cell differentiation GO:0045595 142 0.016
cellular protein complex assembly GO:0043623 19 0.016
negative regulation of gene expression GO:0010629 65 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
reactive oxygen species metabolic process GO:0072593 6 0.016
spermatid development GO:0007286 2 0.016
Fly
positive regulation of neuron apoptotic process GO:0043525 1 0.016
microtubule based process GO:0007017 60 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
nitric oxide metabolic process GO:0046209 2 0.016
positive regulation of metabolic process GO:0009893 108 0.015
multicellular organismal reproductive process GO:0048609 35 0.015
Fly
hemopoiesis GO:0030097 183 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
glial cell migration GO:0008347 3 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
mitochondrion organization GO:0007005 4 0.015
Fly
determination of dorsal ventral asymmetry GO:0048262 34 0.015
cell substrate junction assembly GO:0007044 2 0.015
developmental programmed cell death GO:0010623 4 0.015
growth GO:0040007 174 0.015
regulation of transcription dna templated GO:0006355 213 0.015
cell migration GO:0016477 237 0.015
negative regulation of kinase activity GO:0033673 4 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
negative regulation of biosynthetic process GO:0009890 55 0.015
pronuclear migration GO:0035046 1 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
regulation of rna metabolic process GO:0051252 224 0.015
cellular response to external stimulus GO:0071496 2 0.015
organic acid metabolic process GO:0006082 31 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
single organism nuclear import GO:1902593 3 0.015
regulation of protein polymerization GO:0032271 2 0.015
oxoacid metabolic process GO:0043436 31 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
regulation of tube size GO:0035150 2 0.014
pigmentation GO:0043473 85 0.014
protein import into nucleus GO:0006606 3 0.014
response to external biotic stimulus GO:0043207 97 0.014
convergent extension GO:0060026 118 0.014
reproduction GO:0000003 40 0.014
Fly
gtp catabolic process GO:0006184 2 0.014
striated muscle tissue development GO:0014706 110 0.014
female gonad development GO:0008585 4 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of biosynthetic process GO:0009889 250 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
cytoskeleton organization GO:0007010 96 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
regulation of signaling GO:0023051 235 0.014
gastrulation GO:0007369 208 0.014
neuron development GO:0048666 262 0.014
embryonic skeletal system morphogenesis GO:0048704 93 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
regulation of translational initiation GO:0006446 1 0.014
apoptotic process involved in development GO:1902742 2 0.014
cellular component disassembly GO:0022411 1 0.014
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
ribonucleotide biosynthetic process GO:0009260 20 0.013
eye morphogenesis GO:0048592 144 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
response to external stimulus GO:0009605 264 0.013
Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.013
protein localization to plasma membrane GO:0072659 1 0.013
regulation of protein catabolic process GO:0042176 1 0.013
positive regulation of stem cell proliferation GO:2000648 1 0.013
sensory system development GO:0048880 76 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
purine containing compound metabolic process GO:0072521 29 0.013
lateral line system development GO:0048925 76 0.013
er nucleus signaling pathway GO:0006984 2 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
regulation of catalytic activity GO:0050790 55 0.013
skeletal system development GO:0001501 181 0.013
nerve development GO:0021675 45 0.013
single organism metabolic process GO:0044710 217 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
negative regulation of developmental process GO:0051093 65 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
negative regulation of nucleic acid templated transcription GO:1903507 45 0.013
ribonucleoside biosynthetic process GO:0042455 2 0.013
programmed cell death GO:0012501 119 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
protein complex subunit organization GO:0071822 46 0.013
lamellipodium organization GO:0097581 1 0.013
embryonic heart tube development GO:0035050 133 0.013
heart looping GO:0001947 94 0.013
cation transmembrane transport GO:0098655 65 0.013
regulation of protein targeting GO:1903533 2 0.013
response to carbohydrate GO:0009743 3 0.013
secondary metabolic process GO:0019748 3 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
metal ion transport GO:0030001 58 0.012
spermatid differentiation GO:0048515 2 0.012
Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
nucleoside triphosphate biosynthetic process GO:0009142 2 0.012
circulatory system process GO:0003013 87 0.012
positive regulation of catabolic process GO:0009896 4 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
cation transport GO:0006812 81 0.012
segmentation GO:0035282 97 0.012
nucleic acid templated transcription GO:0097659 181 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
response to topologically incorrect protein GO:0035966 2 0.012
positive regulation of neuron death GO:1901216 1 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
cellular protein catabolic process GO:0044257 4 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
peptide metabolic process GO:0006518 1 0.012
camera type eye development GO:0043010 222 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
response to uv GO:0009411 3 0.012
anterior posterior pattern specification GO:0009952 152 0.012
leukocyte proliferation GO:0070661 1 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
germ line stem cell maintenance GO:0030718 2 0.012
ameboidal type cell migration GO:0001667 143 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
actin filament polymerization GO:0030041 2 0.012
regionalization GO:0003002 274 0.012
cellular protein modification process GO:0006464 100 0.011
electron transport chain GO:0022900 2 0.011
centrosome duplication GO:0051298 1 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
protein phosphorylation GO:0006468 47 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
alternative mrna splicing via spliceosome GO:0000380 1 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
response to other organism GO:0051707 97 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
cognition GO:0050890 1 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
skeletal muscle organ development GO:0060538 78 0.011
regulation of mesenchymal cell proliferation GO:0010464 1 0.011
mesenchymal cell proliferation GO:0010463 1 0.011
regulation of blood pressure GO:0008217 1 0.011
regulation of signal transduction GO:0009966 225 0.011
regulation of dna templated transcription in response to stress GO:0043620 0 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
nuclear import GO:0051170 3 0.011
digestive system development GO:0055123 289 0.011
regulation of circadian rhythm GO:0042752 4 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
atp catabolic process GO:0006200 4 0.011
skeletal system morphogenesis GO:0048705 102 0.011
protein targeting to nucleus GO:0044744 3 0.011
positive regulation of cytokine production GO:0001819 2 0.011
regulation of myotube differentiation GO:0010830 2 0.011
regulation of muscle contraction GO:0006937 3 0.011
cellular macromolecular complex assembly GO:0034622 24 0.011
peptidyl threonine modification GO:0018210 1 0.011
pole plasm assembly GO:0007315 4 0.011
inorganic cation transmembrane transport GO:0098662 50 0.011
central nervous system development GO:0007417 387 0.011
female sex differentiation GO:0046660 4 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
proepicardium development GO:0003342 4 0.011
response to wounding GO:0009611 116 0.010
protein metabolic process GO:0019538 183 0.010
positive regulation of cell activation GO:0050867 1 0.010
neurotransmitter transport GO:0006836 2 0.010
single organism membrane organization GO:0044802 20 0.010
multicellular organism reproduction GO:0032504 35 0.010
Fly
embryonic viscerocranium morphogenesis GO:0048703 52 0.010
specification of organ axis polarity GO:0010084 2 0.010
cellular localization GO:0051641 97 0.010
actomyosin structure organization GO:0031032 53 0.010
locomotion GO:0040011 313 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
negative regulation of signal transduction GO:0009968 94 0.010
negative regulation of striated muscle tissue development GO:0045843 2 0.010
inner ear morphogenesis GO:0042472 63 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
immune system process GO:0002376 241 0.010
ear morphogenesis GO:0042471 64 0.010
regulation of autophagy GO:0010506 3 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
response to glucose GO:0009749 3 0.010
determination of bilateral symmetry GO:0009855 204 0.010
purine nucleotide metabolic process GO:0006163 27 0.010

vdac2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
disease of metabolism DOID:0014667 0 0.028
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
nervous system disease DOID:863 0 0.014