Danio rerio

41 known processes

wdr69

WD repeat domain 69

(Aliases: zgc:153626,si:dkey-223n17.5,zgc:153780)

wdr69 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium movement GO:0003341 26 0.671
epithelial cilium movement GO:0003351 15 0.660
regulation of developmental process GO:0050793 247 0.374
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.326
localization of cell GO:0051674 244 0.321
cellular component movement GO:0006928 335 0.254
cell morphogenesis GO:0000902 289 0.238
determination of bilateral symmetry GO:0009855 204 0.229
determination of left right symmetry GO:0007368 179 0.227
cell part morphogenesis GO:0032990 246 0.214
cellular component morphogenesis GO:0032989 336 0.203
embryo development ending in birth or egg hatching GO:0009792 271 0.189
cilium morphogenesis GO:0060271 85 0.178
larval development GO:0002164 2 0.170
specification of symmetry GO:0009799 204 0.159
neuron differentiation GO:0030182 353 0.122
regulation of multicellular organismal process GO:0051239 277 0.113
neural tube development GO:0021915 62 0.100
regulation of multicellular organismal development GO:2000026 223 0.098
cell motility GO:0048870 244 0.091
somite development GO:0061053 96 0.084
chordate embryonic development GO:0043009 271 0.084
regulation of cell communication GO:0010646 232 0.079
determination of heart left right asymmetry GO:0061371 117 0.078
cell projection organization GO:0030030 284 0.078
regionalization GO:0003002 274 0.063
negative regulation of signal transduction GO:0009968 94 0.059
regulation of cell differentiation GO:0045595 142 0.055
generation of neurons GO:0048699 385 0.053
primary neural tube formation GO:0014020 1 0.053
developmental growth GO:0048589 166 0.052
locomotion GO:0040011 313 0.051
specification of axis polarity GO:0065001 4 0.051
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.051
transcription dna templated GO:0006351 181 0.050
regulation of cellular biosynthetic process GO:0031326 245 0.050
cilium movement involved in cell motility GO:0060294 3 0.049
response to drug GO:0042493 3 0.049
regulation of cell development GO:0060284 100 0.047
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.046
dorsal ventral pattern formation GO:0009953 125 0.044
regulation of cytokine production GO:0001817 3 0.044
regulation of signaling GO:0023051 235 0.043
regulation of macromolecule biosynthetic process GO:0010556 225 0.041
negative regulation of signaling GO:0023057 96 0.041
reproductive process GO:0022414 40 0.041
gene expression GO:0010467 252 0.041
neuroblast differentiation GO:0014016 1 0.040
regulation of response to stimulus GO:0048583 269 0.039
regulation of retina development in camera type eye GO:1902866 2 0.038
rna metabolic process GO:0016070 219 0.038
heart development GO:0007507 313 0.038
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.038
glial cell migration GO:0008347 3 0.037
heart looping GO:0001947 94 0.037
regulation of glial cell differentiation GO:0045685 4 0.037
cellular macromolecule biosynthetic process GO:0034645 224 0.035
nucleobase containing compound biosynthetic process GO:0034654 205 0.035
cellular ketone metabolic process GO:0042180 11 0.034
heterocycle biosynthetic process GO:0018130 215 0.034
cellular biosynthetic process GO:0044249 286 0.033
organelle organization GO:0006996 227 0.033
regulation of nucleic acid templated transcription GO:1903506 213 0.033
extracellular matrix organization GO:0030198 27 0.032
regulation of protein transport GO:0051223 3 0.032
regulation of signal transduction GO:0009966 225 0.032
regulation of nervous system development GO:0051960 90 0.032
regulation of rna biosynthetic process GO:2001141 213 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.031
neuron projection development GO:0031175 180 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.030
microtubule based process GO:0007017 60 0.030
regulation of transcription dna templated GO:0006355 213 0.030
central nervous system development GO:0007417 387 0.029
aromatic compound biosynthetic process GO:0019438 217 0.029
regulation of anatomical structure morphogenesis GO:0022603 130 0.029
protein import into nucleus GO:0006606 3 0.029
tube morphogenesis GO:0035239 349 0.028
negative regulation of cell communication GO:0010648 96 0.027
regulation of inner ear receptor cell differentiation GO:2000980 1 0.027
cellular component assembly involved in morphogenesis GO:0010927 107 0.027
digestive tract morphogenesis GO:0048546 231 0.027
regulation of gene expression GO:0010468 265 0.026
cell projection assembly GO:0030031 64 0.026
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.025
regulation of dna replication GO:0006275 3 0.025
aging GO:0007568 2 0.025
neuromast development GO:0048884 46 0.025
positive regulation of transport GO:0051050 2 0.025
cell projection morphogenesis GO:0048858 244 0.025
transcription from rna polymerase ii promoter GO:0006366 80 0.025
macromolecular complex disassembly GO:0032984 1 0.025
negative regulation of ras protein signal transduction GO:0046580 1 0.025
regulation of protein depolymerization GO:1901879 1 0.024
cytoskeleton organization GO:0007010 96 0.024
protein complex disassembly GO:0043241 1 0.024
axis specification GO:0009798 43 0.024
organelle assembly GO:0070925 110 0.024
myelination GO:0042552 18 0.024
hindbrain formation GO:0021576 3 0.024
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.024
gliogenesis GO:0042063 45 0.023
digestive system development GO:0055123 289 0.023
proximal distal pattern formation GO:0009954 1 0.023
convergent extension GO:0060026 118 0.023
positive regulation of secretion GO:0051047 1 0.023
regulation of biosynthetic process GO:0009889 250 0.023
regulation of dendrite development GO:0050773 3 0.023
lipid storage GO:0019915 1 0.023
cilium organization GO:0044782 71 0.023
response to chemical GO:0042221 320 0.022
rna biosynthetic process GO:0032774 181 0.022
response to antibiotic GO:0046677 1 0.022
regulation of neural retina development GO:0061074 2 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
signal transduction GO:0007165 455 0.022
regulation of microtubule cytoskeleton organization GO:0070507 3 0.021
tube closure GO:0060606 1 0.021
system process GO:0003008 185 0.021
head development GO:0060322 303 0.021
organic substance biosynthetic process GO:1901576 289 0.021
single organism organelle organization GO:1902589 199 0.020
cilium assembly GO:0042384 58 0.020
anterior posterior pattern specification GO:0009952 152 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
embryonic organ morphogenesis GO:0048562 274 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
blood circulation GO:0008015 87 0.019
heart morphogenesis GO:0003007 156 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
segmentation GO:0035282 97 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
neuron projection morphogenesis GO:0048812 161 0.019
oligodendrocyte cell fate specification GO:0021778 4 0.019
nucleic acid templated transcription GO:0097659 181 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
morphogenesis of an epithelium GO:0002009 333 0.019
liver development GO:0001889 96 0.019
determination of liver left right asymmetry GO:0071910 11 0.018
regulation of microtubule based movement GO:0060632 3 0.018
oxoacid metabolic process GO:0043436 31 0.018
transmission of nerve impulse GO:0019226 19 0.018
cellular component disassembly GO:0022411 1 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
positive regulation of nervous system development GO:0051962 25 0.018
regulation of muscle contraction GO:0006937 3 0.018
negative regulation of gliogenesis GO:0014014 1 0.018
peptidyl serine modification GO:0018209 2 0.018
positive regulation of multicellular organismal process GO:0051240 52 0.018
axon development GO:0061564 166 0.017
lipid digestion GO:0044241 3 0.017
aflatoxin b1 metabolic process GO:0043390 1 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
lymphocyte proliferation GO:0046651 1 0.017
mediolateral intercalation GO:0060031 3 0.017
cellular amine metabolic process GO:0044106 2 0.017
multicellular organismal signaling GO:0035637 22 0.017
epithelial cell morphogenesis involved in gastrulation GO:0003381 1 0.016
negative regulation of epithelial cell proliferation GO:0050680 1 0.016
cellular modified amino acid metabolic process GO:0006575 3 0.016
muscle structure development GO:0061061 196 0.016
negative regulation of biological process GO:0048519 304 0.016
intracellular signal transduction GO:0035556 85 0.016
patterning of lymph vessels GO:0060854 1 0.016
multicellular organism reproduction GO:0032504 35 0.016
proximal tubule development GO:0072014 3 0.016
maintenance of location GO:0051235 4 0.016
growth GO:0040007 174 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.016
rhombomere 4 morphogenesis GO:0021661 5 0.015
negative regulation of cytokine production GO:0001818 1 0.015
cellular component biogenesis GO:0044085 178 0.015
epidermal cell differentiation GO:0009913 36 0.015
nucleic acid metabolic process GO:0090304 244 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
centrosome duplication GO:0051298 1 0.015
glial cell differentiation GO:0010001 42 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
compound eye development GO:0048749 2 0.015
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.015
organic cyclic compound metabolic process GO:1901360 301 0.015
lymph vessel morphogenesis GO:0036303 25 0.015
single organism nuclear import GO:1902593 3 0.014
embryonic organ development GO:0048568 381 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
brain development GO:0007420 293 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
positive regulation of cell cycle GO:0045787 3 0.014
response to vitamin b3 GO:0033552 2 0.014
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.013
cellular response to retinoic acid GO:0071300 1 0.013
female sex differentiation GO:0046660 4 0.013
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.013
establishment of localization in cell GO:0051649 77 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
positive regulation of biological process GO:0048518 253 0.013
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.013
protein targeting to nucleus GO:0044744 3 0.013
regulation of protein catabolic process GO:0042176 1 0.013
protein localization to nucleus GO:0034504 3 0.013
regulation of cell shape GO:0008360 1 0.013
regulation of protein targeting GO:1903533 2 0.013
gland development GO:0048732 143 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
ventricular system development GO:0021591 12 0.013
heterocycle metabolic process GO:0046483 290 0.013
gamete generation GO:0007276 33 0.012
regulation of metabolic process GO:0019222 359 0.012
urogenital system development GO:0001655 97 0.012
nuclear import GO:0051170 3 0.012
protein secretion GO:0009306 1 0.012
extracellular structure organization GO:0043062 27 0.012
neuron development GO:0048666 262 0.012
gtp catabolic process GO:0006184 2 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
convergent extension involved in gastrulation GO:0060027 71 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
regulation of wnt signaling pathway GO:0030111 53 0.012
positive regulation of catabolic process GO:0009896 4 0.012
microtubule cytoskeleton organization GO:0000226 33 0.012
neuromast mantle cell differentiation GO:0048888 1 0.012
sensory organ development GO:0007423 393 0.012
negative regulation of stem cell differentiation GO:2000737 2 0.012
cellular response to external stimulus GO:0071496 2 0.012
regulation of rna metabolic process GO:0051252 224 0.011
axonemal dynein complex assembly GO:0070286 5 0.011
phagocytosis GO:0006909 3 0.011
secondary metabolic process GO:0019748 3 0.011
cellular amino acid biosynthetic process GO:0008652 2 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
regulation of cell activation GO:0050865 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
microtubule bundle formation GO:0001578 9 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
single organism reproductive process GO:0044702 40 0.011
cell proliferation in forebrain GO:0021846 3 0.011
action potential GO:0001508 19 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
melanin metabolic process GO:0006582 2 0.010
transport GO:0006810 220 0.010
mitotic cytokinesis GO:0000281 3 0.010
circulatory system process GO:0003013 87 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
cell migration GO:0016477 237 0.010
neuronal action potential GO:0019228 18 0.010
organic acid metabolic process GO:0006082 31 0.010
glial cell fate specification GO:0021780 4 0.010

wdr69 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.071
bone disease DOID:0080001 0 0.071
disease of anatomical entity DOID:7 0 0.071
musculoskeletal system disease DOID:17 0 0.071
connective tissue disease DOID:65 0 0.071
nervous system disease DOID:863 0 0.055
epilepsy syndrome DOID:1826 0 0.035
central nervous system disease DOID:331 0 0.035
brain disease DOID:936 0 0.035
electroclinical syndrome DOID:0050701 0 0.035
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011