Danio rerio

70 known processes

pth2

parathyroid hormone 2

(Aliases: tip39)

pth2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular process GO:0048523 283 0.783
regulation of cellular metabolic process GO:0031323 320 0.691
muscle cell development GO:0055001 115 0.460
muscle cell differentiation GO:0042692 139 0.380
locomotion GO:0040011 313 0.372
ion transmembrane transport GO:0034220 91 0.369
response to external stimulus GO:0009605 264 0.361
negative regulation of biological process GO:0048519 304 0.342
cellular component movement GO:0006928 335 0.334
cellular aromatic compound metabolic process GO:0006725 295 0.314
cell projection organization GO:0030030 284 0.303
regulation of transcription dna templated GO:0006355 213 0.302
signal transduction GO:0007165 455 0.301
establishment of localization GO:0051234 244 0.299
vasculature development GO:0001944 278 0.296
cellular nitrogen compound metabolic process GO:0034641 290 0.283
regulation of sequestering of calcium ion GO:0051282 4 0.283
response to alkaloid GO:0043279 2 0.282
cell motility GO:0048870 244 0.265
regulation of ion transmembrane transporter activity GO:0032412 2 0.265
circadian sleep wake cycle process GO:0022410 2 0.258
hepatic duct development GO:0061011 2 0.258
transport GO:0006810 220 0.253
organonitrogen compound biosynthetic process GO:1901566 47 0.248
blood vessel morphogenesis GO:0048514 216 0.240
striated muscle cell development GO:0055002 108 0.238
transmembrane transport GO:0055085 120 0.224
positive regulation of metabolic process GO:0009893 108 0.209
regulation of macromolecule metabolic process GO:0060255 317 0.206
homeostatic process GO:0042592 142 0.205
circulatory system process GO:0003013 87 0.205
nucleic acid templated transcription GO:0097659 181 0.204
hepatocyte proliferation GO:0072574 2 0.195
regulation of response to stimulus GO:0048583 269 0.193
regulation of nitrogen compound metabolic process GO:0051171 251 0.187
aromatic compound biosynthetic process GO:0019438 217 0.187
nitrogen compound metabolic process GO:0006807 319 0.187
regulation of metabolic process GO:0019222 359 0.180
anterior head development GO:0097065 2 0.168
regulation of multicellular organismal process GO:0051239 277 0.166
neuron projection development GO:0031175 180 0.153
regulation of cellular biosynthetic process GO:0031326 245 0.149
single organism transport GO:0044765 206 0.148
maintenance of location GO:0051235 4 0.143
blood vessel development GO:0001568 246 0.141
sequestering of metal ion GO:0051238 3 0.140
nucleic acid metabolic process GO:0090304 244 0.131
phosphate containing compound metabolic process GO:0006796 108 0.128
muscle fiber development GO:0048747 52 0.127
protein import GO:0017038 3 0.120
sequestering of calcium ion GO:0051208 3 0.119
striated muscle cell differentiation GO:0051146 129 0.117
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.116
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.116
head development GO:0060322 303 0.115
myotube differentiation GO:0014902 45 0.114
cell migration GO:0016477 237 0.113
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.113
negative regulation of response to stimulus GO:0048585 104 0.109
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.108
negative regulation of innate immune response GO:0045824 2 0.108
positive regulation of cellular metabolic process GO:0031325 94 0.104
response to chemical GO:0042221 320 0.103
positive regulation of macromolecule metabolic process GO:0010604 93 0.100
nucleobase containing compound metabolic process GO:0006139 274 0.096
nucleobase containing compound biosynthetic process GO:0034654 205 0.095
neural tube patterning GO:0021532 33 0.088
skeletal muscle organ development GO:0060538 78 0.087
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.085
cell surface receptor signaling pathway GO:0007166 325 0.085
single organism nuclear import GO:1902593 3 0.082
regulation of primary metabolic process GO:0080090 311 0.082
regulation of cell differentiation GO:0045595 142 0.078
digestive tract morphogenesis GO:0048546 231 0.077
optic placode formation involved in camera type eye formation GO:0046619 3 0.076
organic substance transport GO:0071702 58 0.076
cardiac muscle cell development GO:0055013 20 0.074
positive regulation of cellular process GO:0048522 201 0.074
single organism localization GO:1902578 225 0.072
multicellular organism growth GO:0035264 4 0.072
calcium ion transport into cytosol GO:0060402 3 0.071
establishment of localization in cell GO:0051649 77 0.071
regulation of multicellular organismal development GO:2000026 223 0.071
cellular component morphogenesis GO:0032989 336 0.071
negative regulation of cell differentiation GO:0045596 46 0.070
cellular component assembly involved in morphogenesis GO:0010927 107 0.069
regulation of programmed cell death GO:0043067 101 0.069
biosynthetic process GO:0009058 294 0.069
intracellular signal transduction GO:0035556 85 0.067
regulation of biological quality GO:0065008 263 0.065
axon guidance GO:0007411 86 0.065
embryonic digestive tract morphogenesis GO:0048557 3 0.065
skeletal muscle tissue development GO:0007519 67 0.064
regulation of signaling GO:0023051 235 0.063
negative regulation of cell communication GO:0010648 96 0.063
regulation of developmental process GO:0050793 247 0.062
protein metabolic process GO:0019538 183 0.062
regionalization GO:0003002 274 0.062
calcium ion homeostasis GO:0055074 19 0.061
negative regulation of signaling GO:0023057 96 0.061
heterocycle biosynthetic process GO:0018130 215 0.061
nucleocytoplasmic transport GO:0006913 4 0.060
organic cyclic compound biosynthetic process GO:1901362 223 0.060
organelle organization GO:0006996 227 0.058
taxis GO:0042330 109 0.057
muscle organ development GO:0007517 101 0.056
organic substance biosynthetic process GO:1901576 289 0.055
negative regulation of sequestering of calcium ion GO:0051283 4 0.055
heart contraction GO:0060047 71 0.055
regeneration GO:0031099 91 0.055
heart development GO:0007507 313 0.054
regulation of multicellular organism growth GO:0040014 4 0.054
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.053
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.053
regulation of rna biosynthetic process GO:2001141 213 0.052
regulation of biosynthetic process GO:0009889 250 0.052
aging GO:0007568 2 0.052
response to stress GO:0006950 263 0.051
cellular nitrogen compound biosynthetic process GO:0044271 218 0.051
regulation of homeostatic process GO:0032844 9 0.051
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.051
sensory system development GO:0048880 76 0.051
regulation of growth GO:0040008 42 0.051
specification of symmetry GO:0009799 204 0.050
membrane repolarization GO:0086009 2 0.050
nuclear transport GO:0051169 4 0.050
regulation of heart contraction GO:0008016 32 0.050
metal ion transport GO:0030001 58 0.049
ameboidal type cell migration GO:0001667 143 0.049
startle response GO:0001964 4 0.049
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.049
regulation of oligodendrocyte differentiation GO:0048713 1 0.048
cellular response to hypoxia GO:0071456 1 0.048
macromolecule biosynthetic process GO:0009059 227 0.048
purine ribonucleotide biosynthetic process GO:0009152 20 0.048
regulation of cell communication GO:0010646 232 0.047
response to endogenous stimulus GO:0009719 83 0.047
regulation of molecular function GO:0065009 70 0.046
positive regulation of transport GO:0051050 2 0.046
establishment of protein localization to organelle GO:0072594 4 0.045
embryonic heart tube morphogenesis GO:0003143 108 0.044
amino acid transport GO:0006865 2 0.044
gene expression GO:0010467 252 0.044
regulation of catalytic activity GO:0050790 55 0.044
otolith formation GO:0032475 2 0.043
heterocycle metabolic process GO:0046483 290 0.042
programmed cell death GO:0012501 119 0.042
multi organism process GO:0051704 134 0.041
ubiquitin dependent protein catabolic process GO:0006511 3 0.041
cellular localization GO:0051641 97 0.041
actin filament based process GO:0030029 64 0.041
eye morphogenesis GO:0048592 144 0.041
transcription from rna polymerase ii promoter GO:0006366 80 0.041
single organism organelle organization GO:1902589 199 0.041
embryonic organ morphogenesis GO:0048562 274 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.040
organic cyclic compound metabolic process GO:1901360 301 0.040
muscle tissue development GO:0060537 110 0.040
cellular component biogenesis GO:0044085 178 0.040
embryo development ending in birth or egg hatching GO:0009792 271 0.040
regulation of circadian rhythm GO:0042752 4 0.040
cyclic nucleotide metabolic process GO:0009187 18 0.039
epithelial tube morphogenesis GO:0060562 148 0.039
negative regulation of signal transduction GO:0009968 94 0.039
regulation of apoptotic process GO:0042981 98 0.039
gall bladder development GO:0061010 1 0.038
cell death GO:0008219 121 0.038
regulation of localization GO:0032879 104 0.037
heart process GO:0003015 71 0.037
axonogenesis GO:0007409 152 0.037
myotube cell development GO:0014904 35 0.037
circadian sleep wake cycle sleep GO:0050802 1 0.037
growth GO:0040007 174 0.036
chemotaxis GO:0006935 104 0.036
positive regulation of catalytic activity GO:0043085 25 0.036
cell proliferation GO:0008283 80 0.036
heart morphogenesis GO:0003007 156 0.036
protein localization to nucleus GO:0034504 3 0.035
endodermal digestive tract morphogenesis GO:0061031 2 0.035
response to organic substance GO:0010033 153 0.034
regulation of rna metabolic process GO:0051252 224 0.034
regulation of skeletal muscle fiber development GO:0048742 2 0.034
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.034
cardiac cell development GO:0055006 21 0.034
striated muscle tissue development GO:0014706 110 0.033
transcription dna templated GO:0006351 181 0.033
regulation of locomotion GO:0040012 55 0.033
response to food GO:0032094 1 0.032
muscle cell fate determination GO:0007521 1 0.032
phosphorus metabolic process GO:0006793 109 0.032
inorganic cation transmembrane transport GO:0098662 50 0.032
spinal cord anterior posterior patterning GO:0021512 1 0.031
axon development GO:0061564 166 0.031
protein targeting to nucleus GO:0044744 3 0.031
cell cycle GO:0007049 93 0.031
sensory organ morphogenesis GO:0090596 200 0.031
cellular macromolecule metabolic process GO:0044260 391 0.030
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
brain development GO:0007420 293 0.030
regulation of cell death GO:0010941 103 0.030
forebrain development GO:0030900 96 0.030
regulation of nervous system development GO:0051960 90 0.030
adult behavior GO:0030534 2 0.030
regulation of stem cell proliferation GO:0072091 2 0.030
blood circulation GO:0008015 87 0.029
inorganic ion transmembrane transport GO:0098660 57 0.029
developmental programmed cell death GO:0010623 4 0.029
multicellular organismal water homeostasis GO:0050891 1 0.029
macromolecule localization GO:0033036 54 0.029
skeletal system morphogenesis GO:0048705 102 0.028
regulation of nucleocytoplasmic transport GO:0046822 2 0.028
regulation of anterior head development GO:2000742 2 0.028
tube morphogenesis GO:0035239 349 0.028
positive regulation of cellular biosynthetic process GO:0031328 68 0.028
regulation of intracellular protein transport GO:0033157 3 0.028
regulation of nucleic acid templated transcription GO:1903506 213 0.028
skeletal muscle fiber development GO:0048741 35 0.028
lipid catabolic process GO:0016042 4 0.028
regulation of developmental growth GO:0048638 38 0.028
developmental growth involved in morphogenesis GO:0060560 86 0.027
regulation of calcium ion dependent exocytosis GO:0017158 1 0.027
cellular response to endogenous stimulus GO:0071495 68 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.027
regulation of cellular ph GO:0030641 1 0.027
lipid storage GO:0019915 1 0.026
positive regulation of biosynthetic process GO:0009891 68 0.026
response to hormone GO:0009725 48 0.026
chemical homeostasis GO:0048878 49 0.026
regulation of neurogenesis GO:0050767 87 0.026
regulation of cell morphogenesis GO:0022604 42 0.026
localization of cell GO:0051674 244 0.025
cellular protein modification process GO:0006464 100 0.025
post embryonic morphogenesis GO:0009886 4 0.025
regulation of kinase activity GO:0043549 15 0.025
neuromast development GO:0048884 46 0.024
cellular response to oxygen levels GO:0071453 1 0.024
stem cell proliferation GO:0072089 4 0.024
organelle assembly GO:0070925 110 0.024
ribonucleotide metabolic process GO:0009259 27 0.024
heart field specification GO:0003128 1 0.024
cardiac cell fate commitment GO:0060911 1 0.024
regulation of transporter activity GO:0032409 2 0.024
regulation of circadian sleep wake cycle GO:0042749 1 0.024
system process GO:0003008 185 0.024
central nervous system development GO:0007417 387 0.024
protein import into nucleus GO:0006606 3 0.024
positive regulation of transcription dna templated GO:0045893 57 0.023
negative regulation of homeostatic process GO:0032845 5 0.023
nitrogen compound transport GO:0071705 23 0.023
regulation of postsynaptic membrane potential GO:0060078 1 0.023
regulation of sodium ion transport GO:0002028 2 0.023
positive regulation of blood circulation GO:1903524 2 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.023
regulation of intracellular signal transduction GO:1902531 57 0.023
regulation of cellular component organization GO:0051128 86 0.023
positive regulation of cell cycle GO:0045787 3 0.023
camp biosynthetic process GO:0006171 11 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
embryonic organ development GO:0048568 381 0.022
single organism biosynthetic process GO:0044711 71 0.021
somite development GO:0061053 96 0.021
somitogenesis GO:0001756 87 0.021
inner ear morphogenesis GO:0042472 63 0.021
cation transmembrane transport GO:0098655 65 0.021
detection of external stimulus GO:0009581 24 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.021
regulation of neurological system process GO:0031644 2 0.021
larval development GO:0002164 2 0.021
intracellular estrogen receptor signaling pathway GO:0030520 3 0.020
peptide transport GO:0015833 1 0.020
regulation of membrane potential GO:0042391 23 0.020
cellular biosynthetic process GO:0044249 286 0.020
death GO:0016265 121 0.020
regulation of lipid catabolic process GO:0050994 2 0.020
cation homeostasis GO:0055080 33 0.020
regulation of phosphorus metabolic process GO:0051174 43 0.020
neural crest cell differentiation GO:0014033 72 0.020
positive regulation of secretion GO:0051047 1 0.020
negative regulation of cell death GO:0060548 60 0.019
angiogenesis GO:0001525 158 0.019
ion transport GO:0006811 114 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
positive regulation of striated muscle tissue development GO:0045844 1 0.019
leukocyte proliferation GO:0070661 1 0.019
nuclear import GO:0051170 3 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.019
behavior GO:0007610 74 0.018
sleep GO:0030431 1 0.018
regulation of reproductive process GO:2000241 4 0.018
regulation of blood circulation GO:1903522 32 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
intracellular transport GO:0046907 32 0.018
peptidyl lysine methylation GO:0018022 3 0.018
positive regulation of catabolic process GO:0009896 4 0.018
regulation of gene expression GO:0010468 265 0.017
retina development in camera type eye GO:0060041 146 0.017
cartilage morphogenesis GO:0060536 13 0.017
apoptotic process GO:0006915 116 0.017
axon extension GO:0048675 45 0.017
immune system process GO:0002376 241 0.017
protein modification process GO:0036211 100 0.017
hindbrain development GO:0030902 91 0.017
myeloid cell differentiation GO:0030099 86 0.017
regulation of protein import into nucleus GO:0042306 2 0.016
cellular protein metabolic process GO:0044267 129 0.016
neuron fate determination GO:0048664 2 0.016
endocardial cushion morphogenesis GO:0003203 3 0.016
metal ion homeostasis GO:0055065 26 0.016
release of sequestered calcium ion into cytosol GO:0051209 3 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
regulation of skeletal muscle tissue development GO:0048641 4 0.016
cardiac conduction system development GO:0003161 1 0.016
macromolecule modification GO:0043412 111 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
neuron projection extension GO:1990138 45 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.016
fin regeneration GO:0031101 51 0.016
developmental growth GO:0048589 166 0.016
epithelial cell differentiation GO:0030855 116 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.015
response to nicotine GO:0035094 2 0.015
negative regulation of wnt signaling pathway GO:0030178 30 0.015
detection of stimulus GO:0051606 29 0.015
ion homeostasis GO:0050801 41 0.015
protein localization GO:0008104 40 0.015
homeostasis of number of cells GO:0048872 62 0.015
central nervous system neuron differentiation GO:0021953 74 0.015
eye development GO:0001654 277 0.015
sensory perception of pain GO:0019233 1 0.015
negative regulation of immune response GO:0050777 2 0.015
cytosolic calcium ion transport GO:0060401 3 0.015
tissue remodeling GO:0048771 4 0.015
regulation of signal transduction GO:0009966 225 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
oxoacid metabolic process GO:0043436 31 0.014
pigmentation GO:0043473 85 0.014
regulation of anatomical structure size GO:0090066 33 0.014
negative regulation of intracellular signal transduction GO:1902532 22 0.014
positive regulation of phosphorus metabolic process GO:0010562 21 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
posterior lateral line neuromast development GO:0048919 20 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
heart looping GO:0001947 94 0.014
response to light stimulus GO:0009416 46 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
regulation of phosphorylation GO:0042325 26 0.013
cation transport GO:0006812 81 0.013
regulation of cell development GO:0060284 100 0.013
regulation of transmembrane transport GO:0034762 18 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
trabecula morphogenesis GO:0061383 2 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
embryonic camera type eye morphogenesis GO:0048596 19 0.013
gastrulation GO:0007369 208 0.013
protein complex biogenesis GO:0070271 30 0.013
regulation of neuron differentiation GO:0045664 56 0.013
lateral line development GO:0048882 66 0.013
response to oxygen containing compound GO:1901700 55 0.013
detection of mechanical stimulus GO:0050982 11 0.012
sensory organ development GO:0007423 393 0.012
peptidyl lysine trimethylation GO:0018023 1 0.012
response to organic cyclic compound GO:0014070 51 0.012
locomotory behavior GO:0007626 34 0.012
cellular homeostasis GO:0019725 26 0.012
positive regulation of gene expression GO:0010628 71 0.012
cellular response to drug GO:0035690 1 0.012
positive regulation of signaling GO:0023056 56 0.012
glial cell migration GO:0008347 3 0.012
positive regulation of rna metabolic process GO:0051254 59 0.012
mediolateral intercalation GO:0060031 3 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
divalent inorganic cation transport GO:0072511 21 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
rna biosynthetic process GO:0032774 181 0.012
heart formation GO:0060914 13 0.012
post anal tail morphogenesis GO:0036342 19 0.012
carbohydrate derivative biosynthetic process GO:1901137 43 0.012
connective tissue development GO:0061448 99 0.012
regulation of protein transport GO:0051223 3 0.012
divalent inorganic cation homeostasis GO:0072507 22 0.012
urogenital system development GO:0001655 97 0.012
regulation of extent of cell growth GO:0061387 29 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
regulation of cell division GO:0051302 12 0.012
regulation of neuron migration GO:2001222 2 0.012
positive regulation of muscle tissue development GO:1901863 1 0.011
negative regulation of metabolic process GO:0009892 86 0.011
regulation of behavior GO:0050795 24 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.011
regulation of protein metabolic process GO:0051246 56 0.011
regulation of axon extension GO:0030516 24 0.011
cellular component assembly GO:0022607 170 0.011
response to wounding GO:0009611 116 0.011
gland morphogenesis GO:0022612 13 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
organophosphate metabolic process GO:0019637 37 0.011
atrioventricular valve formation GO:0003190 3 0.011
posterior lateral line system development GO:0048915 46 0.011
chondrocyte intercalation involved in growth plate cartilage morphogenesis GO:0003428 1 0.011
ovulation cycle GO:0042698 2 0.011
organelle localization GO:0051640 49 0.011
regulation of filopodium assembly GO:0051489 2 0.011
cell aging GO:0007569 2 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.011
response to glucose GO:0009749 3 0.011
cellular cation homeostasis GO:0030003 17 0.011
embryonic neurocranium morphogenesis GO:0048702 15 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
thalamus development GO:0021794 6 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
regulation of transport GO:0051049 45 0.011
muscle hypertrophy GO:0014896 2 0.011
negative regulation of blood circulation GO:1903523 2 0.011
exocytosis GO:0006887 1 0.011
small molecule metabolic process GO:0044281 77 0.011
cell growth GO:0016049 57 0.011
neurological system process GO:0050877 62 0.011
neuron development GO:0048666 262 0.011
regulation of cell projection organization GO:0031344 44 0.010
cytoplasmic transport GO:0016482 11 0.010
positive regulation of muscle organ development GO:0048636 1 0.010
regulation of blood pressure GO:0008217 1 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
water homeostasis GO:0030104 4 0.010
ribonucleotide biosynthetic process GO:0009260 20 0.010

pth2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
cardiovascular system disease DOID:1287 0 0.031
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.017