Danio rerio

0 known processes

LOC100149056

pannexin-3-like

LOC100149056 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein activation cascade GO:0072376 6 0.147
signal transduction GO:0007165 455 0.088
larval development GO:0002164 2 0.080
defense response GO:0006952 47 0.077
aging GO:0007568 2 0.077
activation of immune response GO:0002253 9 0.070
complement activation GO:0006956 3 0.065
immune system process GO:0002376 241 0.062
response to vitamin b3 GO:0033552 2 0.059
blood vessel development GO:0001568 246 0.054
positive regulation of transport GO:0051050 2 0.054
response to stress GO:0006950 263 0.049
response to vitamin GO:0033273 3 0.045
embryonic organ development GO:0048568 381 0.044
regulation of establishment of protein localization GO:0070201 4 0.044
response to bacterium GO:0009617 58 0.044
lipid storage GO:0019915 1 0.044
response to external stimulus GO:0009605 264 0.043
response to chemical GO:0042221 320 0.043
tube morphogenesis GO:0035239 349 0.042
response to other organism GO:0051707 97 0.042
regulation of inflammatory response GO:0050727 2 0.041
regulation of biological quality GO:0065008 263 0.041
transmembrane transport GO:0055085 120 0.040
protein secretion GO:0009306 1 0.040
sensory organ development GO:0007423 393 0.040
regulation of response to stimulus GO:0048583 269 0.038
regulation of protein transport GO:0051223 3 0.037
maintenance of location GO:0051235 4 0.036
immunoglobulin mediated immune response GO:0016064 3 0.035
system process GO:0003008 185 0.034
multicellular organism growth GO:0035264 4 0.034
cellular extravasation GO:0045123 1 0.034
digestive tract morphogenesis GO:0048546 231 0.034
response to organic substance GO:0010033 153 0.034
carbon dioxide transport GO:0015670 3 0.034
embryonic heart tube development GO:0035050 133 0.034
response to nutrient GO:0007584 3 0.033
response to external biotic stimulus GO:0043207 97 0.033
inorganic anion transport GO:0015698 25 0.033
protein stabilization GO:0050821 2 0.033
embryonic organ morphogenesis GO:0048562 274 0.032
ion transmembrane transport GO:0034220 91 0.031
cellular amine metabolic process GO:0044106 2 0.030
phagocytosis GO:0006909 3 0.030
regulation of cytokine production GO:0001817 3 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.029
positive regulation of dna metabolic process GO:0051054 1 0.029
biosynthetic process GO:0009058 294 0.029
amine metabolic process GO:0009308 2 0.029
muscle cell development GO:0055001 115 0.028
blood vessel morphogenesis GO:0048514 216 0.028
regulation of ph GO:0006885 3 0.028
vasculature development GO:0001944 278 0.028
water transport GO:0006833 15 0.028
determination of bilateral symmetry GO:0009855 204 0.027
regulation of metabolic process GO:0019222 359 0.027
response to biotic stimulus GO:0009607 97 0.027
positive regulation of secretion by cell GO:1903532 1 0.027
single organism metabolic process GO:0044710 217 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
defense response to other organism GO:0098542 33 0.027
positive regulation of biological process GO:0048518 253 0.026
cellular response to nutrient levels GO:0031669 2 0.026
striated muscle cell development GO:0055002 108 0.026
regulation of production of molecular mediator of immune response GO:0002700 1 0.026
oxoacid metabolic process GO:0043436 31 0.026
heterocycle metabolic process GO:0046483 290 0.026
cellular response to external stimulus GO:0071496 2 0.025
somatic muscle development GO:0007525 4 0.025
cellular response to extracellular stimulus GO:0031668 2 0.025
response to hexose GO:0009746 3 0.025
specification of symmetry GO:0009799 204 0.025
positive regulation of cytokine production GO:0001819 2 0.024
chemosensory behavior GO:0007635 1 0.024
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.024
multi organism process GO:0051704 134 0.024
neuron neuron synaptic transmission GO:0007270 1 0.024
autophagy GO:0006914 4 0.024
regulation of blood vessel size GO:0050880 2 0.024
response to monosaccharide GO:0034284 3 0.023
response to drug GO:0042493 3 0.023
sensory perception of chemical stimulus GO:0007606 3 0.023
gastrulation GO:0007369 208 0.023
establishment of localization GO:0051234 244 0.023
production of molecular mediator of immune response GO:0002440 2 0.023
positive regulation of secretion GO:0051047 1 0.023
regulation of carbohydrate metabolic process GO:0006109 4 0.023
one carbon compound transport GO:0019755 14 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
stem cell maintenance GO:0019827 4 0.022
multicellular organismal metabolic process GO:0044236 2 0.022
rna metabolic process GO:0016070 219 0.022
locomotion GO:0040011 313 0.022
regulation of muscle contraction GO:0006937 3 0.022
cell surface receptor signaling pathway GO:0007166 325 0.022
immune effector process GO:0002252 23 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
reactive oxygen species biosynthetic process GO:1903409 1 0.022
cellular response to starvation GO:0009267 1 0.022
b cell mediated immunity GO:0019724 3 0.022
regulation of cell communication GO:0010646 232 0.021
regulation of signal transduction GO:0009966 225 0.021
cellular response to chemical stimulus GO:0070887 157 0.021
positive regulation of cell activation GO:0050867 1 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
regulation of response to nutrient levels GO:0032107 1 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
compound eye development GO:0048749 2 0.021
phosphatidylinositol mediated signaling GO:0048015 2 0.021
response to carbohydrate GO:0009743 3 0.021
gene expression GO:0010467 252 0.021
hormone transport GO:0009914 2 0.020
regulation of metal ion transport GO:0010959 4 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
g protein coupled receptor signaling pathway GO:0007186 74 0.020
regulation of hormone secretion GO:0046883 2 0.020
response to glucocorticoid GO:0051384 1 0.020
regulation of growth rate GO:0040009 1 0.020
regulation of gene expression GO:0010468 265 0.020
regulation of tube size GO:0035150 2 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
heart development GO:0007507 313 0.020
adult behavior GO:0030534 2 0.019
gas transport GO:0015669 3 0.019
multicellular organismal macromolecule metabolic process GO:0044259 2 0.019
digestive system development GO:0055123 289 0.019
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.019
regulation of blood pressure GO:0008217 1 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
organic substance biosynthetic process GO:1901576 289 0.019
cellular response to lipopolysaccharide GO:0071222 3 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
regulation of signaling GO:0023051 235 0.019
protein localization to plasma membrane GO:0072659 1 0.019
positive regulation of map kinase activity GO:0043406 3 0.019
eye development GO:0001654 277 0.018
cellular ketone metabolic process GO:0042180 11 0.018
hormone secretion GO:0046879 2 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
establishment of protein localization to plasma membrane GO:0090002 1 0.018
internal protein amino acid acetylation GO:0006475 2 0.018
cell migration GO:0016477 237 0.018
positive regulation of immune effector process GO:0002699 3 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
digestive tract development GO:0048565 265 0.018
angiogenesis GO:0001525 158 0.018
startle response GO:0001964 4 0.018
muscle organ development GO:0007517 101 0.018
response to ketone GO:1901654 1 0.018
heart morphogenesis GO:0003007 156 0.018
response to glucose GO:0009749 3 0.018
cellular nitrogen compound metabolic process GO:0034641 290 0.018
swimming GO:0036268 3 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
morphogenesis of an epithelium GO:0002009 333 0.017
carbohydrate homeostasis GO:0033500 1 0.017
inositol lipid mediated signaling GO:0048017 2 0.017
b cell activation GO:0042113 2 0.017
neurological system process GO:0050877 62 0.017
leukocyte proliferation GO:0070661 1 0.017
regionalization GO:0003002 274 0.017
mononuclear cell proliferation GO:0032943 1 0.017
regulation of dna replication GO:0006275 3 0.017
inorganic ion transmembrane transport GO:0098660 57 0.017
nitric oxide biosynthetic process GO:0006809 2 0.017
positive regulation of glucose transport GO:0010828 1 0.017
female sex differentiation GO:0046660 4 0.017
cellular macromolecule metabolic process GO:0044260 391 0.017
transport GO:0006810 220 0.016
positive regulation of cellular process GO:0048522 201 0.016
muscle cell differentiation GO:0042692 139 0.016
nitric oxide metabolic process GO:0046209 2 0.016
regulation of primary metabolic process GO:0080090 311 0.016
positive regulation of catabolic process GO:0009896 4 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
organelle assembly GO:0070925 110 0.016
germ line stem cell maintenance GO:0030718 2 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
homeostatic process GO:0042592 142 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
negative regulation of catabolic process GO:0009895 3 0.016
protein import into nucleus GO:0006606 3 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
determination of left right symmetry GO:0007368 179 0.016
ion transport GO:0006811 114 0.016
establishment of protein localization to organelle GO:0072594 4 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
heart looping GO:0001947 94 0.015
single organism nuclear import GO:1902593 3 0.015
regulation of binding GO:0051098 3 0.015
cellular aldehyde metabolic process GO:0006081 4 0.015
negative regulation of biological process GO:0048519 304 0.015
developmental growth GO:0048589 166 0.015
anion transport GO:0006820 38 0.015
regulation of cell activation GO:0050865 1 0.015
brain development GO:0007420 293 0.015
regulation of circadian rhythm GO:0042752 4 0.015
neurotransmitter secretion GO:0007269 2 0.015
negative regulation of cytokine production GO:0001818 1 0.015
stem cell division GO:0017145 1 0.015
peptide transport GO:0015833 1 0.015
multicellular organismal water homeostasis GO:0050891 1 0.015
collagen metabolic process GO:0032963 2 0.015
fluid transport GO:0042044 17 0.015
dicarboxylic acid metabolic process GO:0043648 1 0.015
interaction with host GO:0051701 4 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
single organism transport GO:0044765 206 0.015
regulation of immune system process GO:0002682 34 0.015
energy reserve metabolic process GO:0006112 2 0.015
cell motility GO:0048870 244 0.015
multicellular organismal response to stress GO:0033555 2 0.015
pyruvate metabolic process GO:0006090 1 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
regulation of synaptic plasticity GO:0048167 1 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
stem cell proliferation GO:0072089 4 0.014
tissue regeneration GO:0042246 74 0.014
single organism localization GO:1902578 225 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
protein import GO:0017038 3 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
organic acid metabolic process GO:0006082 31 0.014
regulation of protein catabolic process GO:0042176 1 0.014
glucose homeostasis GO:0042593 1 0.014
immunoglobulin production GO:0002377 1 0.014
striated muscle cell differentiation GO:0051146 129 0.014
nuclear import GO:0051170 3 0.014
immune system development GO:0002520 191 0.014
cellular response to organic substance GO:0071310 105 0.014
regulation of response to cytokine stimulus GO:0060759 3 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
protein homooligomerization GO:0051260 3 0.014
cellular amide metabolic process GO:0043603 4 0.014
chloride transmembrane transport GO:1902476 4 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
positive regulation of immune response GO:0050778 11 0.014
immune response GO:0006955 28 0.014
lymphocyte proliferation GO:0046651 1 0.014
protein heterooligomerization GO:0051291 1 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
multicellular organismal signaling GO:0035637 22 0.014
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
protein targeting to nucleus GO:0044744 3 0.014
regulation of multicellular organismal development GO:2000026 223 0.013
muscle structure development GO:0061061 196 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
phagocytosis engulfment GO:0006911 1 0.013
glucose import GO:0046323 2 0.013
circulatory system process GO:0003013 87 0.013
synaptic vesicle localization GO:0097479 1 0.013
cellular biosynthetic process GO:0044249 286 0.013
central nervous system development GO:0007417 387 0.013
negative regulation of autophagy GO:0010507 1 0.013
nuclear transport GO:0051169 4 0.013
cellular component movement GO:0006928 335 0.013
regulation of cellular metabolic process GO:0031323 320 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
small molecule metabolic process GO:0044281 77 0.013
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
actin filament based movement GO:0030048 1 0.013
response to lipid GO:0033993 60 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
positive regulation of cell cycle GO:0045787 3 0.013
organism emergence from protective structure GO:0071684 4 0.013
regulation of reproductive process GO:2000241 4 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
protein metabolic process GO:0019538 183 0.013
synaptic vesicle transport GO:0048489 1 0.013
regulation of biosynthetic process GO:0009889 250 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
growth GO:0040007 174 0.012
protein localization to nucleus GO:0034504 3 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
negative regulation of defense response GO:0031348 2 0.012
positive regulation of glucose import GO:0046326 1 0.012
regulation of dendrite development GO:0050773 3 0.012
regulation of sodium ion transport GO:0002028 2 0.012
cell substrate adhesion GO:0031589 4 0.012
negative regulation of kinase activity GO:0033673 4 0.012
blood circulation GO:0008015 87 0.012
response to salt stress GO:0009651 10 0.012
interspecies interaction between organisms GO:0044419 4 0.012
protein acylation GO:0043543 3 0.012
water homeostasis GO:0030104 4 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
negative regulation of muscle tissue development GO:1901862 2 0.012
response to alkaloid GO:0043279 2 0.012
regulation of transporter activity GO:0032409 2 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
macromolecule modification GO:0043412 111 0.012
response to corticosteroid GO:0031960 1 0.012
bicarbonate transport GO:0015701 4 0.012
regulation of synapse assembly GO:0051963 3 0.012
kupffer s vesicle development GO:0070121 50 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
carbohydrate transport GO:0008643 13 0.012
regulation of cellular ph GO:0030641 1 0.012
stem cell fate commitment GO:0048865 1 0.012
cellular protein metabolic process GO:0044267 129 0.012
cell matrix adhesion GO:0007160 4 0.012
cellular hormone metabolic process GO:0034754 19 0.012
organic substance transport GO:0071702 58 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
embryonic skeletal system development GO:0048706 97 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
female gonad development GO:0008585 4 0.011
regulation of wound healing GO:0061041 2 0.011
membrane invagination GO:0010324 1 0.011
superoxide metabolic process GO:0006801 2 0.011
regulation of autophagy GO:0010506 3 0.011
peptide metabolic process GO:0006518 1 0.011
positive regulation of wound healing GO:0090303 1 0.011
amino acid transport GO:0006865 2 0.011
erythrocyte development GO:0048821 24 0.011
regeneration GO:0031099 91 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
positive regulation of cell killing GO:0031343 2 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
embryonic skeletal joint development GO:0072498 3 0.011
somatic cell dna recombination GO:0016444 1 0.011
single organism biosynthetic process GO:0044711 71 0.011
nucleic acid metabolic process GO:0090304 244 0.011
positive regulation of reproductive process GO:2000243 2 0.011
regulation of neurological system process GO:0031644 2 0.011
cellular component disassembly GO:0022411 1 0.011
response to endogenous stimulus GO:0009719 83 0.011
response to wounding GO:0009611 116 0.011
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.011
skeletal system development GO:0001501 181 0.011
endocrine process GO:0050886 2 0.011
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
negative regulation of growth rate GO:0045967 1 0.011
detection of chemical stimulus GO:0009593 4 0.011
cellular component morphogenesis GO:0032989 336 0.011
cellular response to xenobiotic stimulus GO:0071466 35 0.011
response to topologically incorrect protein GO:0035966 2 0.011
multi organism cellular process GO:0044764 2 0.011
glycerol transport GO:0015793 7 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
skeletal muscle tissue development GO:0007519 67 0.011
atp catabolic process GO:0006200 4 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
gtp catabolic process GO:0006184 2 0.011
regulation of protein localization to plasma membrane GO:1903076 1 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
regulation of organ growth GO:0046620 3 0.011
striated muscle tissue development GO:0014706 110 0.011
myofibril assembly GO:0030239 48 0.011
cognition GO:0050890 1 0.011
smooth muscle contraction GO:0006939 2 0.011
protein acetylation GO:0006473 2 0.011
hydrogen peroxide metabolic process GO:0042743 2 0.011
sleep GO:0030431 1 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
post embryonic organ development GO:0048569 4 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.010
regulation of intracellular ph GO:0051453 1 0.010
action potential GO:0001508 19 0.010
muscle tissue development GO:0060537 110 0.010
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.010
fertilization GO:0009566 3 0.010
toll like receptor signaling pathway GO:0002224 4 0.010
regulation of rna metabolic process GO:0051252 224 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
regulation of collagen metabolic process GO:0010712 2 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
circadian sleep wake cycle sleep GO:0050802 1 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
activation of mapk activity GO:0000187 3 0.010
regulation of cytokine mediated signaling pathway GO:0001959 3 0.010
heart process GO:0003015 71 0.010
inorganic cation transmembrane transport GO:0098662 50 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
androgen metabolic process GO:0008209 2 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
leukocyte mediated cytotoxicity GO:0001909 1 0.010
cellular response to radiation GO:0071478 4 0.010
hatching GO:0035188 4 0.010
transcription dna templated GO:0006351 181 0.010

LOC100149056 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.023
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
nervous system disease DOID:863 0 0.019
eye disease DOID:5614 0 0.019
musculoskeletal system disease DOID:17 0 0.011