Danio rerio

0 known processes

insb

preproinsulin b

insb biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.252
heart development GO:0007507 313 0.131
locomotion GO:0040011 313 0.123
nitrogen compound metabolic process GO:0006807 319 0.117
generation of neurons GO:0048699 385 0.113
response to chemical GO:0042221 320 0.103
organic cyclic compound metabolic process GO:1901360 301 0.098
specification of symmetry GO:0009799 204 0.093
cellular aromatic compound metabolic process GO:0006725 295 0.088
transmembrane transport GO:0055085 120 0.088
developmental growth GO:0048589 166 0.087
cellular nitrogen compound metabolic process GO:0034641 290 0.086
establishment of localization GO:0051234 244 0.081
regulation of rna metabolic process GO:0051252 224 0.080
gene expression GO:0010467 252 0.077
tube morphogenesis GO:0035239 349 0.077
determination of bilateral symmetry GO:0009855 204 0.075
cell motility GO:0048870 244 0.074
regulation of multicellular organismal process GO:0051239 277 0.073
response to organic substance GO:0010033 153 0.071
regulation of gene expression GO:0010468 265 0.071
neuron differentiation GO:0030182 353 0.071
nucleic acid metabolic process GO:0090304 244 0.071
determination of left right symmetry GO:0007368 179 0.065
gastrulation GO:0007369 208 0.065
regulation of biosynthetic process GO:0009889 250 0.065
notochord development GO:0030903 54 0.065
blood vessel development GO:0001568 246 0.064
heart looping GO:0001947 94 0.064
cellular macromolecule metabolic process GO:0044260 391 0.061
morphogenesis of an epithelium GO:0002009 333 0.060
cell migration GO:0016477 237 0.060
cell morphogenesis GO:0000902 289 0.059
glucose homeostasis GO:0042593 1 0.058
single organism localization GO:1902578 225 0.057
response to external stimulus GO:0009605 264 0.056
regionalization GO:0003002 274 0.056
transport GO:0006810 220 0.056
heterocycle metabolic process GO:0046483 290 0.055
growth GO:0040007 174 0.055
digestive tract development GO:0048565 265 0.055
aromatic compound biosynthetic process GO:0019438 217 0.054
neuron development GO:0048666 262 0.052
cellular biosynthetic process GO:0044249 286 0.052
cellular nitrogen compound biosynthetic process GO:0044271 218 0.052
central nervous system development GO:0007417 387 0.051
convergent extension GO:0060026 118 0.050
cellular component morphogenesis GO:0032989 336 0.049
nucleobase containing compound metabolic process GO:0006139 274 0.048
meiosis ii GO:0007135 1 0.048
dorsal ventral pattern formation GO:0009953 125 0.048
maintenance of location GO:0051235 4 0.047
chemotaxis GO:0006935 104 0.047
negative regulation of biological process GO:0048519 304 0.046
embryo development ending in birth or egg hatching GO:0009792 271 0.046
regulation of developmental process GO:0050793 247 0.046
regulation of rna biosynthetic process GO:2001141 213 0.046
camera type eye development GO:0043010 222 0.045
mesodermal cell differentiation GO:0048333 21 0.045
single organism organelle organization GO:1902589 199 0.043
cellular component movement GO:0006928 335 0.043
anterior posterior pattern specification GO:0009952 152 0.042
peptide transport GO:0015833 1 0.042
gas transport GO:0015669 3 0.042
embryonic organ development GO:0048568 381 0.042
regulation of transcription dna templated GO:0006355 213 0.041
embryonic heart tube morphogenesis GO:0003143 108 0.039
camera type eye morphogenesis GO:0048593 108 0.039
negative regulation of nuclear division GO:0051784 3 0.039
pancreas development GO:0031016 84 0.039
positive regulation of transport GO:0051050 2 0.039
regulation of multicellular organismal development GO:2000026 223 0.039
macromolecule biosynthetic process GO:0009059 227 0.038
aging GO:0007568 2 0.038
negative regulation of cell communication GO:0010648 96 0.038
cellular response to chemical stimulus GO:0070887 157 0.038
developmental growth involved in morphogenesis GO:0060560 86 0.035
angiogenesis GO:0001525 158 0.035
oocyte anterior posterior axis specification GO:0007314 4 0.035
regulation of anatomical structure morphogenesis GO:0022603 130 0.034
embryonic heart tube development GO:0035050 133 0.034
endoderm development GO:0007492 49 0.033
segmentation GO:0035282 97 0.033
specification of organ identity GO:0010092 2 0.033
nucleobase containing compound biosynthetic process GO:0034654 205 0.033
positive regulation of biological process GO:0048518 253 0.033
digestive system development GO:0055123 289 0.033
sensory organ morphogenesis GO:0090596 200 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
digestive tract morphogenesis GO:0048546 231 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.032
eye morphogenesis GO:0048592 144 0.032
axis specification GO:0009798 43 0.032
ion transmembrane transport GO:0034220 91 0.031
mesoderm development GO:0007498 88 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.031
maternal determination of anterior posterior axis embryo GO:0008358 4 0.031
rna biosynthetic process GO:0032774 181 0.031
determination of heart left right asymmetry GO:0061371 117 0.030
sensory organ development GO:0007423 393 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.030
heart morphogenesis GO:0003007 156 0.030
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.030
multi organism process GO:0051704 134 0.029
hormone secretion GO:0046879 2 0.029
ion transport GO:0006811 114 0.029
epithelial tube morphogenesis GO:0060562 148 0.029
ameboidal type cell migration GO:0001667 143 0.028
single organism transport GO:0044765 206 0.028
carbohydrate homeostasis GO:0033500 1 0.028
regulation of cell communication GO:0010646 232 0.028
embryonic organ morphogenesis GO:0048562 274 0.028
biosynthetic process GO:0009058 294 0.028
regulation of signal transduction GO:0009966 225 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.027
positive regulation of cytoskeleton organization GO:0051495 3 0.027
neurotransmitter secretion GO:0007269 2 0.027
regulation of binding GO:0051098 3 0.027
meiotic chromosome segregation GO:0045132 3 0.026
stem cell maintenance GO:0019827 4 0.026
eye development GO:0001654 277 0.026
negative regulation of cellular process GO:0048523 283 0.026
single organism metabolic process GO:0044710 217 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
meiotic nuclear division GO:0007126 4 0.025
regulation of biological quality GO:0065008 263 0.024
localization of cell GO:0051674 244 0.024
macromolecular complex subunit organization GO:0043933 74 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
cell fate commitment GO:0045165 99 0.023
neurotransmitter transport GO:0006836 2 0.023
hemopoiesis GO:0030097 183 0.023
signal transduction GO:0007165 455 0.023
cell fate specification GO:0001708 68 0.023
vasculature development GO:0001944 278 0.023
regulation of signaling GO:0023051 235 0.023
cellular component biogenesis GO:0044085 178 0.023
heterocycle biosynthetic process GO:0018130 215 0.022
rna metabolic process GO:0016070 219 0.022
renal system development GO:0072001 94 0.022
cell projection morphogenesis GO:0048858 244 0.022
cell part morphogenesis GO:0032990 246 0.022
response to stress GO:0006950 263 0.021
synaptic vesicle transport GO:0048489 1 0.021
regulation of response to stimulus GO:0048583 269 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.021
meiotic cell cycle process GO:1903046 3 0.021
negative regulation of reproductive process GO:2000242 3 0.021
regulation of gastrulation GO:0010470 24 0.021
regulation of hormone secretion GO:0046883 2 0.020
positive regulation of protein complex assembly GO:0031334 2 0.020
response to carbohydrate GO:0009743 3 0.020
gastrulation with mouth forming second GO:0001702 44 0.020
cell projection organization GO:0030030 284 0.020
cellular component assembly GO:0022607 170 0.020
positive regulation of cellular process GO:0048522 201 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
phagocytosis GO:0006909 3 0.020
inner ear development GO:0048839 126 0.019
cation transmembrane transport GO:0098655 65 0.019
small molecule metabolic process GO:0044281 77 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
nucleic acid templated transcription GO:0097659 181 0.019
response to oxygen containing compound GO:1901700 55 0.018
transcription from rna polymerase ii promoter GO:0006366 80 0.018
axonogenesis GO:0007409 152 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
cellular amine metabolic process GO:0044106 2 0.018
organic acid metabolic process GO:0006082 31 0.018
regulation of primary metabolic process GO:0080090 311 0.017
amine metabolic process GO:0009308 2 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
positive regulation of catabolic process GO:0009896 4 0.017
mitotic sister chromatid segregation GO:0000070 6 0.017
muscle organ development GO:0007517 101 0.017
cognition GO:0050890 1 0.017
regulation of cell differentiation GO:0045595 142 0.017
organelle organization GO:0006996 227 0.017
endoderm formation GO:0001706 29 0.017
immune system process GO:0002376 241 0.016
head development GO:0060322 303 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
negative regulation of response to stimulus GO:0048585 104 0.016
hormone transport GO:0009914 2 0.016
regulation of transcription involved in cell fate commitment GO:0060850 1 0.016
response to amphetamine GO:0001975 1 0.016
regulation of chromosome segregation GO:0051983 1 0.016
formation of primary germ layer GO:0001704 62 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
golgi vesicle transport GO:0048193 3 0.016
anterior posterior axis specification GO:0009948 20 0.016
cardiac cell fate commitment GO:0060911 1 0.015
neurological system process GO:0050877 62 0.015
cytoskeleton organization GO:0007010 96 0.015
behavior GO:0007610 74 0.015
inorganic cation transmembrane transport GO:0098662 50 0.015
connective tissue development GO:0061448 99 0.015
mesenchyme development GO:0060485 127 0.015
system process GO:0003008 185 0.015
atp catabolic process GO:0006200 4 0.015
response to organic cyclic compound GO:0014070 51 0.015
axon development GO:0061564 166 0.015
oxoacid metabolic process GO:0043436 31 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
response to endogenous stimulus GO:0009719 83 0.015
positive regulation of protein polymerization GO:0032273 2 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
positive regulation of gene expression GO:0010628 71 0.015
cellular ketone metabolic process GO:0042180 11 0.015
skeletal muscle organ development GO:0060538 78 0.015
embryonic skeletal system morphogenesis GO:0048704 93 0.015
neuron projection development GO:0031175 180 0.015
organelle localization GO:0051640 49 0.014
protein localization to plasma membrane GO:0072659 1 0.014
regulation of cell fate commitment GO:0010453 22 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
chordate embryonic development GO:0043009 271 0.014
rna localization GO:0006403 4 0.014
ear development GO:0043583 127 0.014
regulation of microtubule cytoskeleton organization GO:0070507 3 0.014
negative regulation of signaling GO:0023057 96 0.014
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.014
regulation of reproductive process GO:2000241 4 0.014
brain development GO:0007420 293 0.014
female meiotic division GO:0007143 2 0.014
regulation of cell fate specification GO:0042659 20 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
cardiac atrium morphogenesis GO:0003209 2 0.014
organic substance biosynthetic process GO:1901576 289 0.014
convergent extension involved in gastrulation GO:0060027 71 0.014
response to drug GO:0042493 3 0.014
cytoplasm organization GO:0007028 4 0.014
neural tube development GO:0021915 62 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
multicellular organism growth GO:0035264 4 0.013
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
exocytosis GO:0006887 1 0.013
striated muscle tissue development GO:0014706 110 0.013
taxis GO:0042330 109 0.013
cell growth GO:0016049 57 0.013
fin regeneration GO:0031101 51 0.013
establishment of vesicle localization GO:0051650 24 0.013
embryonic pattern specification GO:0009880 44 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
cellular localization GO:0051641 97 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
response to lipid GO:0033993 60 0.013
muscle structure development GO:0061061 196 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
striated muscle cell development GO:0055002 108 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
synaptic vesicle localization GO:0097479 1 0.013
membrane invagination GO:0010324 1 0.013
muscle cell development GO:0055001 115 0.012
regulation of blood pressure GO:0008217 1 0.012
somite development GO:0061053 96 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
negative regulation of mesodermal cell fate specification GO:0042662 3 0.012
regulation of cell death GO:0010941 103 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
gtp catabolic process GO:0006184 2 0.012
cytokinetic process GO:0032506 2 0.012
negative regulation of signal transduction GO:0009968 94 0.012
intracellular signal transduction GO:0035556 85 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
response to hexose GO:0009746 3 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
negative regulation of metabolic process GO:0009892 86 0.012
cellular component disassembly GO:0022411 1 0.012
canonical wnt signaling pathway GO:0060070 48 0.012
regulation of apoptotic process GO:0042981 98 0.012
adult behavior GO:0030534 2 0.012
fin development GO:0033333 77 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
regeneration GO:0031099 91 0.012
lateral inhibition GO:0046331 1 0.012
cellular response to oxygen levels GO:0071453 1 0.012
transcription dna templated GO:0006351 181 0.012
positive regulation of translation GO:0045727 1 0.012
regulation of ph GO:0006885 3 0.012
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.012
translational initiation GO:0006413 3 0.011
neuron projection guidance GO:0097485 86 0.011
negative regulation of cell fate commitment GO:0010454 13 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
regulation of cell growth GO:0001558 29 0.011
cell death GO:0008219 121 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
endocrine pancreas development GO:0031018 27 0.011
negative regulation of oocyte development GO:0060283 2 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
neuron projection morphogenesis GO:0048812 161 0.011
oocyte maturation GO:0001556 4 0.011
regulation of protein complex assembly GO:0043254 3 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
mesoderm formation GO:0001707 43 0.011
cardiac cell development GO:0055006 21 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of blood vessel size GO:0050880 2 0.011
chemical homeostasis GO:0048878 49 0.011
spemann organizer formation at the embryonic shield GO:0060063 2 0.011
spindle assembly involved in mitosis GO:0090307 1 0.011
organic substance transport GO:0071702 58 0.011
negative regulation of mitosis GO:0045839 3 0.011
regulation of tube size GO:0035150 2 0.011
response to monosaccharide GO:0034284 3 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
sister chromatid cohesion GO:0007062 2 0.011
carbon dioxide transport GO:0015670 3 0.011
skeletal system morphogenesis GO:0048705 102 0.011
immune system development GO:0002520 191 0.011
chemosensory behavior GO:0007635 1 0.010
cell substrate adhesion GO:0031589 4 0.010
establishment of organelle localization GO:0051656 45 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
response to wounding GO:0009611 116 0.010
central nervous system neuron differentiation GO:0021953 74 0.010
cellular protein metabolic process GO:0044267 129 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
ear morphogenesis GO:0042471 64 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
chromosome organization involved in meiosis GO:0070192 1 0.010
sodium ion transmembrane transport GO:0035725 21 0.010
lipid storage GO:0019915 1 0.010

insb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.011
musculoskeletal system disease DOID:17 0 0.010