Danio rerio

0 known processes

nitr5

novel immune-type receptor 5 and immune-type receptor 5-like

(Aliases: nitr5_4,nitr5_5,MGC195260,si:dz263j20.5,nitr5_3,nitr5a,si:dz105l16.3,si:busm1-263j20.5,nitr5.6,nitr5.5,nitr5.4,nitr5.3,nitr5.2,nitr5.1,si:dz219h16.13)

nitr5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of production of molecular mediator of immune response GO:0002700 1 0.104
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.073
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.060
response to external stimulus GO:0009605 264 0.058
Zebrafish
response to other organism GO:0051707 97 0.057
Zebrafish
production of molecular mediator of immune response GO:0002440 2 0.054
larval development GO:0002164 2 0.050
regulation of cytokine production GO:0001817 3 0.049
response to bacterium GO:0009617 58 0.048
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.047
positive regulation of immune effector process GO:0002699 3 0.047
positive regulation of transport GO:0051050 2 0.047
regulation of natural killer cell mediated immunity GO:0002715 1 0.042
positive regulation of cytokine production GO:0001819 2 0.042
response to external biotic stimulus GO:0043207 97 0.042
Zebrafish
multicellular organism growth GO:0035264 4 0.042
immune system process GO:0002376 241 0.041
regulation of response to stimulus GO:0048583 269 0.040
regulation of multicellular organism growth GO:0040014 4 0.039
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.039
Zebrafish
defense response GO:0006952 47 0.038
inositol lipid mediated signaling GO:0048017 2 0.038
Zebrafish
response to stress GO:0006950 263 0.038
cellular response to lipopolysaccharide GO:0071222 3 0.038
regulation of biological quality GO:0065008 263 0.038
leukocyte proliferation GO:0070661 1 0.036
regulation of cellular amine metabolic process GO:0033238 0 0.036
immunoglobulin mediated immune response GO:0016064 3 0.035
protein import into nucleus GO:0006606 3 0.034
phosphatidylinositol mediated signaling GO:0048015 2 0.034
Zebrafish
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
b cell mediated immunity GO:0019724 3 0.033
establishment of protein localization to organelle GO:0072594 4 0.032
amine metabolic process GO:0009308 2 0.032
response to biotic stimulus GO:0009607 97 0.032
Zebrafish
nuclear transport GO:0051169 4 0.031
cellular amine metabolic process GO:0044106 2 0.031
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.031
b cell activation GO:0042113 2 0.030
aging GO:0007568 2 0.030
immune effector process GO:0002252 23 0.029
mononuclear cell proliferation GO:0032943 1 0.029
organonitrogen compound metabolic process GO:1901564 74 0.028
regulation of protein transport GO:0051223 3 0.028
single organism nuclear import GO:1902593 3 0.028
protein targeting to nucleus GO:0044744 3 0.028
positive regulation of cell cycle GO:0045787 3 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
signal transduction GO:0007165 455 0.027
Zebrafish
positive regulation of biological process GO:0048518 253 0.027
positive regulation of leukocyte mediated immunity GO:0002705 1 0.027
regulation of blood pressure GO:0008217 1 0.027
response to drug GO:0042493 3 0.026
stem cell proliferation GO:0072089 4 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
maintenance of location GO:0051235 4 0.026
cellular amide metabolic process GO:0043603 4 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
protein localization to nucleus GO:0034504 3 0.025
response to glucocorticoid GO:0051384 1 0.025
female sex differentiation GO:0046660 4 0.025
protein acetylation GO:0006473 2 0.024
protein import GO:0017038 3 0.024
nuclear import GO:0051170 3 0.024
response to corticosteroid GO:0031960 1 0.024
regulation of cell activation GO:0050865 1 0.024
protein acylation GO:0043543 3 0.024
autophagy GO:0006914 4 0.024
cellular ketone metabolic process GO:0042180 11 0.024
sensory perception of chemical stimulus GO:0007606 3 0.023
internal protein amino acid acetylation GO:0006475 2 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
internal peptidyl lysine acetylation GO:0018393 2 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
peptidyl lysine acetylation GO:0018394 2 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.023
regulation of metal ion transport GO:0010959 4 0.023
lymphocyte proliferation GO:0046651 1 0.022
hemopoiesis GO:0030097 183 0.022
response to chemical GO:0042221 320 0.022
organic acid metabolic process GO:0006082 31 0.022
cellular response to biotic stimulus GO:0071216 3 0.022
cellular response to external stimulus GO:0071496 2 0.022
positive regulation of cell activation GO:0050867 1 0.022
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.022
regulation of gene expression GO:0010468 265 0.022
oxoacid metabolic process GO:0043436 31 0.022
protein secretion GO:0009306 1 0.022
regulation of metabolic process GO:0019222 359 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
negative regulation of cytokine production GO:0001818 1 0.021
cellular response to molecule of bacterial origin GO:0071219 3 0.021
immunoglobulin production GO:0002377 1 0.021
positive regulation of catabolic process GO:0009896 4 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
gastrulation GO:0007369 208 0.021
regulation of protein catabolic process GO:0042176 1 0.021
digestive tract morphogenesis GO:0048546 231 0.021
response to nutrient GO:0007584 3 0.021
regulation of binding GO:0051098 3 0.020
lipid storage GO:0019915 1 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
leukocyte mediated cytotoxicity GO:0001909 1 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
regulation of circadian rhythm GO:0042752 4 0.020
sleep GO:0030431 1 0.020
tube morphogenesis GO:0035239 349 0.020
antimicrobial humoral response GO:0019730 2 0.020
regulation of response to nutrient levels GO:0032107 1 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
immune system development GO:0002520 191 0.020
heart development GO:0007507 313 0.019
female gonad development GO:0008585 4 0.019
single organism metabolic process GO:0044710 217 0.019
response to virus GO:0009615 21 0.019
cellular macromolecule metabolic process GO:0044260 391 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
positive regulation of secretion GO:0051047 1 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
multi organism process GO:0051704 134 0.018
Zebrafish
cellular protein catabolic process GO:0044257 4 0.018
phagocytosis GO:0006909 3 0.018
gtp metabolic process GO:0046039 4 0.018
growth GO:0040007 174 0.018
gene expression GO:0010467 252 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
positive regulation of dna metabolic process GO:0051054 1 0.018
regulation of tube size GO:0035150 2 0.018
regulation of primary metabolic process GO:0080090 311 0.018
response to organic substance GO:0010033 153 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
heterocycle metabolic process GO:0046483 290 0.018
interspecies interaction between organisms GO:0044419 4 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
somatic cell dna recombination GO:0016444 1 0.018
organic substance biosynthetic process GO:1901576 289 0.018
somatic muscle development GO:0007525 4 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
small molecule metabolic process GO:0044281 77 0.018
complement activation GO:0006956 3 0.018
modification dependent protein catabolic process GO:0019941 3 0.017
intracellular signal transduction GO:0035556 85 0.017
Zebrafish
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
nucleic acid templated transcription GO:0097659 181 0.017
vasculature development GO:0001944 278 0.017
positive regulation of cellular process GO:0048522 201 0.017
regulation of transporter activity GO:0032409 2 0.017
cell killing GO:0001906 2 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
biosynthetic process GO:0009058 294 0.017
blood vessel development GO:0001568 246 0.017
regulation of dna recombination GO:0000018 2 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
cellular response to nutrient levels GO:0031669 2 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
regulation of sodium ion transport GO:0002028 2 0.017
lymphocyte mediated immunity GO:0002449 5 0.017
regulation of autophagy GO:0010506 3 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
protein heterooligomerization GO:0051291 1 0.017
regulation of response to biotic stimulus GO:0002831 2 0.017
hormone secretion GO:0046879 2 0.017
cytokinesis GO:0000910 3 0.016
regulation of blood vessel size GO:0050880 2 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
stem cell division GO:0017145 1 0.016
regulation of ph GO:0006885 3 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
regulation of immune system process GO:0002682 34 0.016
detection of chemical stimulus involved in sensory perception GO:0050907 3 0.016
angiogenesis GO:0001525 158 0.016
regulation of muscle contraction GO:0006937 3 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
peptide transport GO:0015833 1 0.016
embryonic organ development GO:0048568 381 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
digestive tract development GO:0048565 265 0.016
regulation of leukocyte mediated immunity GO:0002703 1 0.016
tissue remodeling GO:0048771 4 0.016
rna biosynthetic process GO:0032774 181 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
negative regulation of secretion by cell GO:1903531 2 0.016
negative regulation of catabolic process GO:0009895 3 0.015
positive regulation of myeloid cell differentiation GO:0045639 2 0.015
regulation of jak stat cascade GO:0046425 3 0.015
regulation of organelle assembly GO:1902115 4 0.015
gtp catabolic process GO:0006184 2 0.015
cellular biosynthetic process GO:0044249 286 0.015
organic cyclic compound metabolic process GO:1901360 301 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
rna metabolic process GO:0016070 219 0.015
establishment of localization GO:0051234 244 0.015
cellular response to starvation GO:0009267 1 0.015
centrosome organization GO:0051297 1 0.015
digestive system development GO:0055123 289 0.015
defense response to other organism GO:0098542 33 0.015
protein metabolic process GO:0019538 183 0.015
spermatid development GO:0007286 2 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
hormone transport GO:0009914 2 0.015
meiotic cell cycle process GO:1903046 3 0.015
response to lipid GO:0033993 60 0.015
peptide metabolic process GO:0006518 1 0.015
negative regulation of defense response GO:0031348 2 0.015
endocrine process GO:0050886 2 0.015
adult behavior GO:0030534 2 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
positive regulation of cell killing GO:0031343 2 0.014
membrane invagination GO:0010324 1 0.014
compound eye development GO:0048749 2 0.014
regulation of reproductive process GO:2000241 4 0.014
macroautophagy GO:0016236 1 0.014
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.014
transcription dna templated GO:0006351 181 0.014
regulation of hormone secretion GO:0046883 2 0.014
system process GO:0003008 185 0.014
cellular response to organic substance GO:0071310 105 0.014
regulation of developmental process GO:0050793 247 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
odontogenesis of dentin containing tooth GO:0042475 1 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
secondary metabolic process GO:0019748 3 0.014
regulation of synapse assembly GO:0051963 3 0.014
regulation of wound healing GO:0061041 2 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
phagocytosis engulfment GO:0006911 1 0.014
positive regulation of leukocyte differentiation GO:1902107 1 0.014
regulation of biosynthetic process GO:0009889 250 0.014
developmental growth GO:0048589 166 0.014
regulation of signal transduction GO:0009966 225 0.014
positive regulation of jnk cascade GO:0046330 3 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
circulatory system process GO:0003013 87 0.014
adaptive immune response GO:0002250 5 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
regulation of response to cytokine stimulus GO:0060759 3 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
response to ketone GO:1901654 1 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
positive regulation of chromosome organization GO:2001252 1 0.013
response to carbohydrate GO:0009743 3 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
tube closure GO:0060606 1 0.013
response to monosaccharide GO:0034284 3 0.013
regulation of organ growth GO:0046620 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
activation of mapk activity GO:0000187 3 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
positive regulation of inflammatory response GO:0050729 1 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
positive regulation of multi organism process GO:0043902 3 0.013
cell migration GO:0016477 237 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
blood circulation GO:0008015 87 0.013
cellular protein metabolic process GO:0044267 129 0.013
response to vitamin GO:0033273 3 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of cellular metabolic process GO:0031323 320 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
positive regulation of histone modification GO:0031058 1 0.013
regionalization GO:0003002 274 0.013
regulation of protein complex assembly GO:0043254 3 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
transport GO:0006810 220 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
blood vessel morphogenesis GO:0048514 216 0.012
negative regulation of protein transport GO:0051224 3 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
cellular response to radiation GO:0071478 4 0.012
immune response GO:0006955 28 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.012
endosomal transport GO:0016197 2 0.012
p38mapk cascade GO:0038066 1 0.012
circadian sleep wake cycle GO:0042745 2 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
detection of chemical stimulus GO:0009593 4 0.012
positive regulation of natural killer cell mediated immunity GO:0002717 1 0.012
regulation of protein targeting GO:1903533 2 0.012
establishment of endothelial barrier GO:0061028 3 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
atp catabolic process GO:0006200 4 0.012
negative regulation of autophagy GO:0010507 1 0.012
regulation of circadian sleep wake cycle GO:0042749 1 0.012
ion transport GO:0006811 114 0.012
sensory organ development GO:0007423 393 0.012
adherens junction organization GO:0034332 4 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
positive regulation of cell division GO:0051781 2 0.012
response to abiotic stimulus GO:0009628 122 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
cell proliferation GO:0008283 80 0.012
positive regulation of gliogenesis GO:0014015 2 0.012
spermatid differentiation GO:0048515 2 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
response to uv GO:0009411 3 0.012
mitochondrion organization GO:0007005 4 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
protein localization to plasma membrane GO:0072659 1 0.011
macromolecule modification GO:0043412 111 0.011
post embryonic morphogenesis GO:0009886 4 0.011
protein complex disassembly GO:0043241 1 0.011
locomotion GO:0040011 313 0.011
stem cell maintenance GO:0019827 4 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
regulation of cell killing GO:0031341 2 0.011
regulation of cell shape GO:0008360 1 0.011
regulation of signaling GO:0023051 235 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
positive regulation of translation GO:0045727 1 0.011
defense response to virus GO:0051607 10 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
meiotic nuclear division GO:0007126 4 0.011
liver development GO:0001889 96 0.011
multicellular organismal response to stress GO:0033555 2 0.011
renal tubule morphogenesis GO:0061333 1 0.011
regulation of response to stress GO:0080134 36 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
somatic stem cell maintenance GO:0035019 1 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
negative regulation of biological process GO:0048519 304 0.011
response to hexose GO:0009746 3 0.011
regulation of gtpase activity GO:0043087 2 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
golgi vesicle transport GO:0048193 3 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
insulin like growth factor receptor signaling pathway GO:0048009 4 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
regulation of cell communication GO:0010646 232 0.011
regulation of cellular ph GO:0030641 1 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
camera type eye development GO:0043010 222 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
rna localization GO:0006403 4 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
single organism transport GO:0044765 206 0.011
regulation of intracellular ph GO:0051453 1 0.011
response to alkaloid GO:0043279 2 0.011
negative regulation of immune response GO:0050777 2 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
neurotransmitter transport GO:0006836 2 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
glucose homeostasis GO:0042593 1 0.011
response to wounding GO:0009611 116 0.011
synaptic transmission cholinergic GO:0007271 4 0.011
neuromuscular process controlling balance GO:0050885 3 0.011
cell morphogenesis GO:0000902 289 0.011
carbohydrate biosynthetic process GO:0016051 1 0.010
activation of immune response GO:0002253 9 0.010
organelle organization GO:0006996 227 0.010
xenobiotic metabolic process GO:0006805 4 0.010
dicarboxylic acid transport GO:0006835 1 0.010
negative regulation of histone modification GO:0031057 1 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.010
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
sex determination GO:0007530 1 0.010
multi organism cellular process GO:0044764 2 0.010
cellular component biogenesis GO:0044085 178 0.010
positive regulation of production of molecular mediator of immune response GO:0002702 1 0.010
post embryonic organ development GO:0048569 4 0.010
dna templated transcription elongation GO:0006354 3 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
leukocyte mediated immunity GO:0002443 6 0.010
regulation of lipid transport GO:0032368 4 0.010
pyruvate metabolic process GO:0006090 1 0.010
negative regulation of protein kinase activity GO:0006469 4 0.010
single organism organelle organization GO:1902589 199 0.010
neurotransmitter secretion GO:0007269 2 0.010
regulation of mesenchymal cell proliferation GO:0010464 1 0.010

nitr5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
musculoskeletal system disease DOID:17 0 0.023
disease of metabolism DOID:0014667 0 0.018
nervous system disease DOID:863 0 0.015
inherited metabolic disorder DOID:655 0 0.014
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
muscular disease DOID:0080000 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011