Danio rerio

0 known processes

ap2m1a

adaptor-related protein complex 2, mu 1 subunit, a

(Aliases: zgc:55711,zgc:85653,cb34,sb:cb34,wu:fa97a10,Ap2m1,dpy-23)

ap2m1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.417
Worm
regulation of cellular ph GO:0030641 1 0.171
positive regulation of cellular component biogenesis GO:0044089 3 0.158
cellular aromatic compound metabolic process GO:0006725 295 0.141
positive regulation of transport GO:0051050 2 0.112
Worm
cellular component assembly involved in morphogenesis GO:0010927 107 0.099
somatic muscle development GO:0007525 4 0.098
actin polymerization or depolymerization GO:0008154 2 0.087
spermatid development GO:0007286 2 0.079
cellular nitrogen compound metabolic process GO:0034641 290 0.079
organic cyclic compound metabolic process GO:1901360 301 0.077
single organism localization GO:1902578 225 0.073
Human Worm Fly
positive regulation of cytoskeleton organization GO:0051495 3 0.069
immune system process GO:0002376 241 0.068
cellular amine metabolic process GO:0044106 2 0.067
lamellipodium organization GO:0097581 1 0.066
nitrogen compound metabolic process GO:0006807 319 0.066
positive regulation of cellular process GO:0048522 201 0.066
Worm
regulation of cellular metabolic process GO:0031323 320 0.064
cell projection organization GO:0030030 284 0.064
regulation of cell projection assembly GO:0060491 4 0.063
cellular component disassembly GO:0022411 1 0.063
endosomal transport GO:0016197 2 0.059
regionalization GO:0003002 274 0.059
positive regulation of biological process GO:0048518 253 0.059
Worm
small molecule metabolic process GO:0044281 77 0.058
leukocyte proliferation GO:0070661 1 0.058
meiotic nuclear division GO:0007126 4 0.058
cilium morphogenesis GO:0060271 85 0.058
positive regulation of protein complex assembly GO:0031334 2 0.058
transport GO:0006810 220 0.057
Worm Fly
protein polymerization GO:0051258 4 0.056
mononuclear cell proliferation GO:0032943 1 0.056
regulation of intracellular ph GO:0051453 1 0.055
aging GO:0007568 2 0.055
regulation of macromolecule metabolic process GO:0060255 317 0.055
regulation of biological quality GO:0065008 263 0.054
lymphocyte proliferation GO:0046651 1 0.053
single fertilization GO:0007338 3 0.053
cellular protein catabolic process GO:0044257 4 0.052
positive regulation of cell cycle GO:0045787 3 0.052
regulation of protein polymerization GO:0032271 2 0.050
phagocytosis GO:0006909 3 0.048
organelle assembly GO:0070925 110 0.047
single organism transport GO:0044765 206 0.047
Worm Fly
carboxylic acid metabolic process GO:0019752 22 0.046
cell projection assembly GO:0030031 64 0.046
protein metabolic process GO:0019538 183 0.046
regulation of protein complex assembly GO:0043254 3 0.044
regulation of cell shape GO:0008360 1 0.044
cellular component morphogenesis GO:0032989 336 0.043
cellular component assembly GO:0022607 170 0.043
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.043
regulation of blood pressure GO:0008217 1 0.043
carbohydrate derivative metabolic process GO:1901135 61 0.043
growth GO:0040007 174 0.042
protein targeting to nucleus GO:0044744 3 0.042
positive regulation of catabolic process GO:0009896 4 0.042
regulation of metabolic process GO:0019222 359 0.041
meiotic cell cycle process GO:1903046 3 0.041
maintenance of location GO:0051235 4 0.040
regulation of cellular amine metabolic process GO:0033238 0 0.040
protein complex disassembly GO:0043241 1 0.040
macromolecule biosynthetic process GO:0009059 227 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
regulation of cellular amino acid metabolic process GO:0006521 0 0.039
phagocytosis engulfment GO:0006911 1 0.039
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.039
lamellipodium assembly GO:0030032 1 0.039
regulation of wound healing GO:0061041 2 0.038
single organism metabolic process GO:0044710 217 0.038
cellular ketone metabolic process GO:0042180 11 0.037
cell morphogenesis GO:0000902 289 0.037
cellular biosynthetic process GO:0044249 286 0.037
cellular macromolecule metabolic process GO:0044260 391 0.036
organelle organization GO:0006996 227 0.035
apoptotic process GO:0006915 116 0.035
single organism organelle organization GO:1902589 199 0.035
maternal determination of anterior posterior axis embryo GO:0008358 4 0.034
cytoskeleton organization GO:0007010 96 0.034
regulation of cell activation GO:0050865 1 0.034
system process GO:0003008 185 0.034
meiotic chromosome segregation GO:0045132 3 0.033
spermatid differentiation GO:0048515 2 0.033
positive regulation of wound healing GO:0090303 1 0.033
organic acid metabolic process GO:0006082 31 0.033
membrane invagination GO:0010324 1 0.032
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.032
amine metabolic process GO:0009308 2 0.032
cellular localization GO:0051641 97 0.032
Human Worm
regulation of intracellular protein transport GO:0033157 3 0.032
exocytosis GO:0006887 1 0.032
positive regulation of cellular catabolic process GO:0031331 3 0.032
regulation of nitrogen compound metabolic process GO:0051171 251 0.031
regulation of nucleoside metabolic process GO:0009118 2 0.031
biosynthetic process GO:0009058 294 0.031
ph reduction GO:0045851 1 0.031
regulation of filopodium assembly GO:0051489 2 0.031
generation of neurons GO:0048699 385 0.031
embryo development ending in birth or egg hatching GO:0009792 271 0.031
Worm
guanosine containing compound metabolic process GO:1901068 4 0.031
regulation of binding GO:0051098 3 0.030
macromolecular complex disassembly GO:0032984 1 0.030
cellular component biogenesis GO:0044085 178 0.030
cell part morphogenesis GO:0032990 246 0.030
heterocycle metabolic process GO:0046483 290 0.030
sexual reproduction GO:0019953 36 0.029
Fly
cell surface receptor signaling pathway GO:0007166 325 0.029
regulation of ph GO:0006885 3 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
cilium assembly GO:0042384 58 0.029
actin filament polymerization GO:0030041 2 0.029
reproduction GO:0000003 40 0.029
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
pole plasm assembly GO:0007315 4 0.028
multi organism reproductive process GO:0044703 36 0.028
Fly
neuron differentiation GO:0030182 353 0.027
cellular response to nutrient levels GO:0031669 2 0.027
cellular amino acid metabolic process GO:0006520 7 0.027
regulation of synapse organization GO:0050807 3 0.027
fertilization GO:0009566 3 0.026
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
germ cell development GO:0007281 22 0.026
Fly
gtp metabolic process GO:0046039 4 0.026
positive regulation of protein polymerization GO:0032273 2 0.026
transcription dna templated GO:0006351 181 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.026
organic substance biosynthetic process GO:1901576 289 0.026
cytokinesis GO:0000910 3 0.026
positive regulation of cell activation GO:0050867 1 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
Worm
gene expression GO:0010467 252 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
regulation of localization GO:0032879 104 0.025
Human Worm
regulation of protein targeting GO:1903533 2 0.025
nucleic acid metabolic process GO:0090304 244 0.025
astrocyte differentiation GO:0048708 1 0.025
protein import into nucleus GO:0006606 3 0.025
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
regulation of protein transport GO:0051223 3 0.024
Worm
protein localization to plasma membrane GO:0072659 1 0.024
Human
multicellular organism growth GO:0035264 4 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
regulation of protein catabolic process GO:0042176 1 0.024
oocyte anterior posterior axis specification GO:0007314 4 0.024
macromolecular complex subunit organization GO:0043933 74 0.024
rna transport GO:0050658 2 0.024
Fly
response to nutrient GO:0007584 3 0.024
protein localization to nucleus GO:0034504 3 0.024
positive regulation of striated muscle cell differentiation GO:0051155 1 0.023
microtubule cytoskeleton organization GO:0000226 33 0.023
regulation of circadian rhythm GO:0042752 4 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
macromolecular complex assembly GO:0065003 35 0.022
response to external stimulus GO:0009605 264 0.022
regulation of response to stimulus GO:0048583 269 0.022
b cell activation GO:0042113 2 0.022
oxoacid metabolic process GO:0043436 31 0.022
erythrocyte homeostasis GO:0034101 55 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
skin development GO:0043588 54 0.022
aromatic compound biosynthetic process GO:0019438 217 0.021
chordate embryonic development GO:0043009 271 0.020
negative regulation of protein complex assembly GO:0031333 1 0.020
regulation of gene expression GO:0010468 265 0.020
cell death GO:0008219 121 0.020
Worm
regulation of reproductive process GO:2000241 4 0.019
cytoplasm organization GO:0007028 4 0.019
positive regulation of muscle cell differentiation GO:0051149 1 0.019
anterior posterior pattern specification GO:0009952 152 0.019
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.019
cytosolic calcium ion transport GO:0060401 3 0.019
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
developmental growth GO:0048589 166 0.019
compound eye development GO:0048749 2 0.018
positive regulation of gtp catabolic process GO:0033126 1 0.018
regulation of developmental process GO:0050793 247 0.018
protein complex assembly GO:0006461 30 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
multicellular organismal signaling GO:0035637 22 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
hormone transport GO:0009914 2 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
gtp catabolic process GO:0006184 2 0.017
long chain fatty acid metabolic process GO:0001676 1 0.017
negative regulation of mapk cascade GO:0043409 4 0.017
hormone secretion GO:0046879 2 0.017
locomotion GO:0040011 313 0.017
Worm
regulation of signal transduction GO:0009966 225 0.017
protein import GO:0017038 3 0.017
protein dephosphorylation GO:0006470 3 0.017
cell cycle g2 m phase transition GO:0044839 4 0.017
intracellular signal transduction GO:0035556 85 0.017
natural killer cell mediated immunity GO:0002228 1 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
programmed cell death GO:0012501 119 0.016
blood circulation GO:0008015 87 0.016
nitrogen compound transport GO:0071705 23 0.016
Fly
developmental maturation GO:0021700 34 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
rna localization GO:0006403 4 0.016
Fly
eye development GO:0001654 277 0.016
circulatory system process GO:0003013 87 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
membrane lipid biosynthetic process GO:0046467 2 0.016
regulation of microtubule cytoskeleton organization GO:0070507 3 0.016
establishment of rna localization GO:0051236 3 0.016
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
iron ion homeostasis GO:0055072 4 0.016
signal transduction in absence of ligand GO:0038034 1 0.016
lateral inhibition GO:0046331 1 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
cellular response to external stimulus GO:0071496 2 0.015
vasculature development GO:0001944 278 0.015
regulation of protein complex disassembly GO:0043244 1 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
nuclear import GO:0051170 3 0.015
cell cell recognition GO:0009988 1 0.015
protein secretion GO:0009306 1 0.015
Worm
golgi vesicle transport GO:0048193 3 0.015
peptidyl threonine phosphorylation GO:0018107 1 0.015
regulation of hormone secretion GO:0046883 2 0.015
peptide transport GO:0015833 1 0.015
cellular amide metabolic process GO:0043603 4 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
response to ketone GO:1901654 1 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
cellular lipid catabolic process GO:0044242 3 0.015
immune system development GO:0002520 191 0.015
positive regulation of secretion GO:0051047 1 0.015
Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
centrosome organization GO:0051297 1 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.014
regulation of synapse assembly GO:0051963 3 0.014
lytic vacuole organization GO:0080171 1 0.014
detection of stimulus GO:0051606 29 0.014
homeostatic process GO:0042592 142 0.014
regulation of blood coagulation GO:0030193 1 0.014
g2 m transition of mitotic cell cycle GO:0000086 4 0.014
digestive tract development GO:0048565 265 0.014
nuclear transport GO:0051169 4 0.014
establishment of localization in cell GO:0051649 77 0.014
Worm
actin filament based process GO:0030029 64 0.014
neurotransmitter transport GO:0006836 2 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
positive regulation of camp metabolic process GO:0030816 2 0.013
adult behavior GO:0030534 2 0.013
regulation of rna metabolic process GO:0051252 224 0.013
defense response GO:0006952 47 0.013
liver development GO:0001889 96 0.013
regulation of natural killer cell mediated immunity GO:0002715 1 0.013
response to stress GO:0006950 263 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
regulation of organelle organization GO:0033043 29 0.013
oocyte maturation GO:0001556 4 0.013
negative regulation of signal transduction GO:0009968 94 0.013
camera type eye development GO:0043010 222 0.013
protein localization GO:0008104 40 0.013
Human Worm Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
er to golgi vesicle mediated transport GO:0006888 1 0.013
cellular protein complex disassembly GO:0043624 1 0.013
regulation of primary metabolic process GO:0080090 311 0.013
regulation of transcription dna templated GO:0006355 213 0.013
response to amino acid GO:0043200 2 0.013
protein depolymerization GO:0051261 1 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
regulation of muscle contraction GO:0006937 3 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
centrosome cycle GO:0007098 1 0.013
regulation of cellular component organization GO:0051128 86 0.012
Human
regulation of nucleotide catabolic process GO:0030811 2 0.012
regulation of biosynthetic process GO:0009889 250 0.012
single organism nuclear import GO:1902593 3 0.012
establishment of localization GO:0051234 244 0.012
Worm Fly
response to glucose GO:0009749 3 0.012
smooth muscle contraction GO:0006939 2 0.012
detection of chemical stimulus GO:0009593 4 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
purine containing compound metabolic process GO:0072521 29 0.012
ion transport GO:0006811 114 0.012
regulation of cytokine production GO:0001817 3 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
adherens junction organization GO:0034332 4 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
lymphocyte homeostasis GO:0002260 1 0.012
myeloid cell homeostasis GO:0002262 56 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
negative regulation of kinase activity GO:0033673 4 0.012
erythrocyte differentiation GO:0030218 54 0.012
cellular response to starvation GO:0009267 1 0.012
cellular transition metal ion homeostasis GO:0046916 3 0.012
positive regulation of response to stimulus GO:0048584 80 0.011
cellular protein metabolic process GO:0044267 129 0.011
ion transmembrane transport GO:0034220 91 0.011
organic substance catabolic process GO:1901575 28 0.011
gamete generation GO:0007276 33 0.011
Fly
protein complex subunit organization GO:0071822 46 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
monovalent inorganic cation homeostasis GO:0055067 9 0.011
regulation of organelle assembly GO:1902115 4 0.011
regulation of signaling GO:0023051 235 0.011
Worm
negative regulation of cellular component organization GO:0051129 16 0.011
Human
protein modification by small protein removal GO:0070646 1 0.011
mitochondrion organization GO:0007005 4 0.011
determination of left right symmetry GO:0007368 179 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
macromolecule modification GO:0043412 111 0.011
regulation of hemostasis GO:1900046 1 0.011
ovulation cycle process GO:0022602 2 0.011
ovulation cycle GO:0042698 2 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
nucleic acid transport GO:0050657 2 0.011
Fly
response to external biotic stimulus GO:0043207 97 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
cell cycle process GO:0022402 53 0.011
nucleic acid templated transcription GO:0097659 181 0.010
positive regulation of secretion by cell GO:1903532 1 0.010
Worm
mitotic cell cycle process GO:1903047 48 0.010
nucleobase containing compound transport GO:0015931 2 0.010
Fly
intracellular mrna localization GO:0008298 1 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010
death GO:0016265 121 0.010
Worm
regulation of circadian sleep wake cycle GO:0042749 1 0.010
stem cell maintenance GO:0019827 4 0.010
regulation of multicellular organismal process GO:0051239 277 0.010
peptidyl serine modification GO:0018209 2 0.010
cell substrate adhesion GO:0031589 4 0.010
regulation of oocyte development GO:0060281 3 0.010
positive regulation of cell division GO:0051781 2 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
neuromuscular process controlling balance GO:0050885 3 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
regulation of response to nutrient levels GO:0032107 1 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
blood vessel development GO:0001568 246 0.010
cell aging GO:0007569 2 0.010
negative regulation of response to stimulus GO:0048585 104 0.010

ap2m1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
musculoskeletal system disease DOID:17 0 0.018
disease of metabolism DOID:0014667 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012