Danio rerio

81 known processes

hand2

heart and neural crest derivatives expressed transcript 2

(Aliases: dhand,zgc:103415,MGC103415,zdHAND)

hand2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.998
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.996
Human Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.992
Human Zebrafish Mouse Fly
heart valve formation GO:0003188 4 0.990
central nervous system development GO:0007417 387 0.990
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.988
cardiac chamber formation GO:0003207 4 0.985
Mouse
embryonic appendage morphogenesis GO:0035113 30 0.979
localization of cell GO:0051674 244 0.963
Mouse
apoptotic process GO:0006915 116 0.955
Mouse Fly
digestive system development GO:0055123 289 0.946
embryonic skeletal system morphogenesis GO:0048704 93 0.938
heart valve morphogenesis GO:0003179 8 0.937
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.935
Human Zebrafish Mouse Fly
otic vesicle formation GO:0030916 27 0.932
cellular aromatic compound metabolic process GO:0006725 295 0.926
Human Zebrafish Mouse Fly
specification of symmetry GO:0009799 204 0.922
regulation of rna metabolic process GO:0051252 224 0.919
Human Zebrafish Mouse Fly
endocrine system development GO:0035270 65 0.917
otic placode formation GO:0043049 23 0.917
atrioventricular valve formation GO:0003190 3 0.917
sensory organ morphogenesis GO:0090596 200 0.916
Zebrafish
positive regulation of nucleic acid templated transcription GO:1903508 57 0.911
Human Zebrafish Mouse Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.910
Fly
otic vesicle morphogenesis GO:0071600 34 0.909
blood vessel morphogenesis GO:0048514 216 0.905
Zebrafish Mouse
pancreas development GO:0031016 84 0.904
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.893
inner ear development GO:0048839 126 0.891
Zebrafish
renal system development GO:0072001 94 0.887
atrial ventricular junction remodeling GO:0003294 2 0.869
embryonic viscerocranium morphogenesis GO:0048703 52 0.866
regionalization GO:0003002 274 0.864
intermediate mesoderm development GO:0048389 2 0.855
biosynthetic process GO:0009058 294 0.852
Human Zebrafish Mouse Fly
neural crest cell development GO:0014032 62 0.847
Mouse
regulation of multicellular organismal development GO:2000026 223 0.846
Zebrafish Mouse
muscle cell differentiation GO:0042692 139 0.831
glomerulus vasculature development GO:0072012 2 0.831
transcription from rna polymerase ii promoter GO:0006366 80 0.830
Human Mouse Fly
neuron development GO:0048666 262 0.826
Zebrafish Mouse Fly
hematopoietic progenitor cell differentiation GO:0002244 23 0.823
Zebrafish
inner ear morphogenesis GO:0042472 63 0.822
heart jogging GO:0003146 40 0.821
regulation of cellular biosynthetic process GO:0031326 245 0.820
Human Zebrafish Mouse Fly
blood vessel development GO:0001568 246 0.820
Zebrafish Mouse
embryonic hemopoiesis GO:0035162 53 0.806
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.794
Human Zebrafish Mouse Fly
kidney development GO:0001822 92 0.793
rna biosynthetic process GO:0032774 181 0.791
Human Zebrafish Mouse Fly
artery morphogenesis GO:0048844 14 0.791
Zebrafish Mouse
pharyngeal muscle development GO:0043282 4 0.785
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.784
Human Zebrafish Mouse Fly
cellular component morphogenesis GO:0032989 336 0.778
Fly
hemopoiesis GO:0030097 183 0.777
Zebrafish Fly
morphogenesis of an epithelium GO:0002009 333 0.770
artery development GO:0060840 22 0.767
Zebrafish Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.766
Human Zebrafish Mouse Fly
myeloid leukocyte differentiation GO:0002573 15 0.766
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.763
Human Zebrafish Mouse Fly
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.754
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.748
Mouse
ear morphogenesis GO:0042471 64 0.746
brain development GO:0007420 293 0.744
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.737
Human Zebrafish Mouse Fly
digestive tract development GO:0048565 265 0.734
macromolecule biosynthetic process GO:0009059 227 0.734
Human Zebrafish Mouse Fly
heterocycle biosynthetic process GO:0018130 215 0.732
Human Zebrafish Mouse Fly
mesoderm development GO:0007498 88 0.730
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 191 0.729
Zebrafish Mouse Fly
tube morphogenesis GO:0035239 349 0.724
regulation of macromolecule metabolic process GO:0060255 317 0.724
Human Zebrafish Mouse Fly
embryonic heart tube morphogenesis GO:0003143 108 0.723
cellular macromolecule biosynthetic process GO:0034645 224 0.722
Human Zebrafish Mouse Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.709
cardiac atrium morphogenesis GO:0003209 2 0.708
bmp signaling pathway involved in heart jogging GO:0003303 14 0.702
regulation of biosynthetic process GO:0009889 250 0.693
Human Zebrafish Mouse Fly
limb bud formation GO:0060174 2 0.693
regulation of programmed cell death GO:0043067 101 0.692
Mouse Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.680
Human Zebrafish Mouse Fly
determination of dorsal ventral asymmetry GO:0048262 34 0.678
determination of bilateral symmetry GO:0009855 204 0.663
cellular macromolecule metabolic process GO:0044260 391 0.661
Human Zebrafish Mouse Fly
heart morphogenesis GO:0003007 156 0.652
ventral spinal cord interneuron differentiation GO:0021514 12 0.645
regulation of multicellular organismal process GO:0051239 277 0.642
Zebrafish Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.635
hematopoietic stem cell differentiation GO:0060218 20 0.634
Zebrafish
taxis GO:0042330 109 0.634
cartilage development GO:0051216 96 0.632
Mouse
regulation of developmental process GO:0050793 247 0.623
Zebrafish Mouse
erythrocyte differentiation GO:0030218 54 0.608
Zebrafish
cellular biosynthetic process GO:0044249 286 0.602
Human Zebrafish Mouse Fly
muscle structure development GO:0061061 196 0.602
atrioventricular valve morphogenesis GO:0003181 6 0.601
cellular nitrogen compound metabolic process GO:0034641 290 0.599
Human Zebrafish Mouse Fly
erythrocyte homeostasis GO:0034101 55 0.594
Zebrafish
endocrine pancreas development GO:0031018 27 0.587
Zebrafish
immune system process GO:0002376 241 0.586
Zebrafish Mouse Fly
rna metabolic process GO:0016070 219 0.586
Human Zebrafish Mouse Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.586
vasculogenesis GO:0001570 41 0.585
Zebrafish
myeloid cell differentiation GO:0030099 86 0.579
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.578
Human Zebrafish Mouse Fly
organic cyclic compound metabolic process GO:1901360 301 0.577
Human Zebrafish Mouse Fly
positive regulation of biological process GO:0048518 253 0.577
Human Zebrafish Mouse Fly
cell motility GO:0048870 244 0.576
Mouse
otic vesicle development GO:0071599 42 0.569
mesoderm morphogenesis GO:0048332 51 0.569
Zebrafish
eye development GO:0001654 277 0.566
Zebrafish
immune system development GO:0002520 191 0.562
Zebrafish Mouse Fly
transcription dna templated GO:0006351 181 0.561
Human Zebrafish Mouse Fly
positive regulation of gene expression GO:0010628 71 0.558
Human Zebrafish Mouse Fly
heart looping GO:0001947 94 0.556
Mouse
kidney vasculature development GO:0061440 2 0.555
positive regulation of rna metabolic process GO:0051254 59 0.554
Human Zebrafish Mouse Fly
thyroid gland development GO:0030878 12 0.548
sensory organ development GO:0007423 393 0.541
Zebrafish Mouse
negative regulation of developmental process GO:0051093 65 0.540
Zebrafish Mouse
neuron projection morphogenesis GO:0048812 161 0.539
Fly
pectoral fin morphogenesis GO:0035138 29 0.539
somite development GO:0061053 96 0.527
positive regulation of transcription dna templated GO:0045893 57 0.524
Human Zebrafish Mouse Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.520
Fly
head development GO:0060322 303 0.517
Zebrafish
cardiac conduction system development GO:0003161 1 0.510
stem cell differentiation GO:0048863 117 0.507
endodermal cell fate specification GO:0001714 17 0.505
appendage morphogenesis GO:0035107 56 0.500
neural crest cell migration GO:0001755 42 0.485
Mouse
neural crest cell differentiation GO:0014033 72 0.484
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.477
Human Zebrafish Mouse Fly
forebrain development GO:0030900 96 0.475
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.474
Human Zebrafish Mouse Fly
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.474
skeletal system development GO:0001501 181 0.473
heart valve development GO:0003170 14 0.471
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.471
aromatic compound biosynthetic process GO:0019438 217 0.465
Human Zebrafish Mouse Fly
positive regulation of biosynthetic process GO:0009891 68 0.464
Human Zebrafish Mouse Fly
oligodendrocyte differentiation GO:0048709 23 0.464
embryonic pectoral fin morphogenesis GO:0035118 24 0.455
proepicardium development GO:0003342 4 0.452
endocardial cushion development GO:0003197 6 0.452
nitrogen compound metabolic process GO:0006807 319 0.452
Human Zebrafish Mouse Fly
semicircular canal development GO:0060872 24 0.445
endothelium development GO:0003158 25 0.444
Zebrafish
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.443
maintenance of location GO:0051235 4 0.440
formation of primary germ layer GO:0001704 62 0.440
Zebrafish
homeostasis of number of cells GO:0048872 62 0.434
Zebrafish
regulation of heart morphogenesis GO:2000826 17 0.433
Mouse
cellular amide metabolic process GO:0043603 4 0.433
negative regulation of cellular process GO:0048523 283 0.431
Zebrafish Mouse Fly
cell projection organization GO:0030030 284 0.430
Zebrafish Fly
regulation of chondrocyte differentiation GO:0032330 1 0.427
aorta development GO:0035904 4 0.425
regulation of gene expression GO:0010468 265 0.420
Human Zebrafish Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.415
Human Zebrafish Mouse Fly
determination of left right symmetry GO:0007368 179 0.414
positive regulation of cellular process GO:0048522 201 0.413
Human Zebrafish Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.412
Human Zebrafish Mouse Fly
fin development GO:0033333 77 0.403
cardiac muscle cell differentiation GO:0055007 30 0.396
cranial suture morphogenesis GO:0060363 1 0.391
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.391
embryonic limb morphogenesis GO:0030326 2 0.381
Mouse
developmental growth GO:0048589 166 0.381
cell morphogenesis GO:0000902 289 0.374
Fly
endothelial cell differentiation GO:0045446 20 0.374
Zebrafish
regulation of cell communication GO:0010646 232 0.372
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.371
Human Mouse Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.365
Mouse
response to stress GO:0006950 263 0.361
Zebrafish
heart development GO:0007507 313 0.360
embryonic camera type eye formation GO:0060900 10 0.347
ectodermal placode development GO:0071696 37 0.346
Zebrafish
appendage development GO:0048736 80 0.346
heart field specification GO:0003128 1 0.338
outflow tract morphogenesis GO:0003151 1 0.335
Mouse
fin morphogenesis GO:0033334 53 0.332
regulation of organ morphogenesis GO:2000027 35 0.330
Mouse
specification of organ position GO:0010159 3 0.329
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.329
skeletal system morphogenesis GO:0048705 102 0.329
signal transduction GO:0007165 455 0.329
Mouse
embryonic neurocranium morphogenesis GO:0048702 15 0.328
odontogenesis of dentin containing tooth GO:0042475 1 0.324
Mouse
embryonic heart tube development GO:0035050 133 0.321
muscle organ development GO:0007517 101 0.321
regulation of cell proliferation GO:0042127 37 0.317
Mouse
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.317
regulation of apoptotic process GO:0042981 98 0.315
Mouse Fly
cardioblast differentiation GO:0010002 9 0.301
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.300
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.297
endocardial cushion morphogenesis GO:0003203 3 0.292
endodermal cell fate determination GO:0007493 2 0.292
regulation of metabolic process GO:0019222 359 0.291
Human Zebrafish Mouse Fly
gene expression GO:0010467 252 0.286
Human Zebrafish Mouse Fly
dorsal ventral pattern formation GO:0009953 125 0.284
regulation of epithelial cell proliferation GO:0050678 3 0.282
pericardium development GO:0060039 1 0.280
Mouse
bmp signaling pathway involved in heart development GO:0061312 15 0.275
heart contraction GO:0060047 71 0.272
behavior GO:0007610 74 0.271
Zebrafish Mouse
regulation of cardiac chamber formation GO:1901210 2 0.269
foregut morphogenesis GO:0007440 4 0.269
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.268
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.266
Human Zebrafish Mouse Fly
endoderm development GO:0007492 49 0.264
somitogenesis GO:0001756 87 0.262
ventricular cardiac muscle tissue development GO:0003229 3 0.255
regulation of rna biosynthetic process GO:2001141 213 0.255
Human Zebrafish Mouse Fly
notochord development GO:0030903 54 0.254
limb development GO:0060173 8 0.253
Mouse
generation of neurons GO:0048699 385 0.246
Zebrafish Mouse Fly
negative regulation of biosynthetic process GO:0009890 55 0.244
atrioventricular valve development GO:0003171 11 0.240
neuron differentiation GO:0030182 353 0.237
Zebrafish Mouse Fly
anterior posterior pattern specification GO:0009952 152 0.230
cell death GO:0008219 121 0.229
Mouse Fly
urogenital system development GO:0001655 97 0.226
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.226
Human Zebrafish Mouse Fly
embryonic pattern specification GO:0009880 44 0.224
spinal cord development GO:0021510 46 0.221
pharyngeal system development GO:0060037 18 0.214
Zebrafish
retinal ganglion cell axon guidance GO:0031290 35 0.213
notochord cell differentiation GO:0060034 18 0.213
positive regulation of muscle organ development GO:0048636 1 0.212
cell migration GO:0016477 237 0.212
Mouse
palate development GO:0060021 8 0.211
Mouse
positive regulation of skeletal muscle tissue development GO:0048643 1 0.210
homeostatic process GO:0042592 142 0.207
Zebrafish
ectodermal placode morphogenesis GO:0071697 32 0.205
regulation of myotube differentiation GO:0010830 2 0.205
regulation of embryonic development GO:0045995 47 0.204
positive regulation of macromolecule metabolic process GO:0010604 93 0.202
Human Zebrafish Mouse Fly
regulation of stem cell proliferation GO:0072091 2 0.201
regulation of signaling GO:0023051 235 0.198
Mouse
positive regulation of apoptotic process GO:0043065 29 0.193
negative regulation of transcription dna templated GO:0045892 45 0.190
cellular nitrogen compound biosynthetic process GO:0044271 218 0.188
Human Zebrafish Mouse Fly
response to chemical GO:0042221 320 0.187
heterocycle metabolic process GO:0046483 290 0.184
Human Zebrafish Mouse Fly
determination of heart left right asymmetry GO:0061371 117 0.182
Mouse
morphogenesis of an epithelial fold GO:0060571 1 0.181
endodermal cell fate commitment GO:0001711 18 0.180
cartilage condensation GO:0001502 3 0.180
positive regulation of metabolic process GO:0009893 108 0.179
Human Zebrafish Mouse Fly
cardiac ventricle development GO:0003231 9 0.178
Mouse
negative regulation of muscle organ development GO:0048635 5 0.177
morphogenesis of an epithelial sheet GO:0002011 49 0.177
multi organism process GO:0051704 134 0.174
Mouse
embryonic skeletal system development GO:0048706 97 0.173
cell migration involved in gastrulation GO:0042074 79 0.169
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.169
mesenchymal cell differentiation GO:0048762 87 0.169
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.169
Human Zebrafish Mouse Fly
gastrulation with mouth forming second GO:0001702 44 0.168
striated muscle cell differentiation GO:0051146 129 0.168
cell fate specification GO:0001708 68 0.163
oligodendrocyte cell fate specification GO:0021778 4 0.162
floor plate formation GO:0021508 12 0.162
protein acylation GO:0043543 3 0.159
regulation of cardiac muscle tissue development GO:0055024 1 0.158
endocardial cushion formation GO:0003272 2 0.154
midbrain development GO:0030901 28 0.154
cell migration involved in heart development GO:0060973 22 0.153
Mouse
glial cell fate specification GO:0021780 4 0.152
pharynx development GO:0060465 5 0.151
digestive tract morphogenesis GO:0048546 231 0.149
Zebrafish
striated muscle cell proliferation GO:0014855 7 0.147
regulation of cardiac chamber morphogenesis GO:1901219 2 0.147
regulation of cardiac muscle cell differentiation GO:2000725 1 0.144
positive regulation of stem cell proliferation GO:2000648 1 0.142
regulation of bone mineralization GO:0030500 2 0.142
negative regulation of cellular metabolic process GO:0031324 77 0.142
mesodermal cell differentiation GO:0048333 21 0.141
Zebrafish
cardiac ventricle formation GO:0003211 1 0.141
Mouse
mesenchyme development GO:0060485 127 0.140
renal tubule morphogenesis GO:0061333 1 0.139
response to metal ion GO:0010038 34 0.138
gastrulation GO:0007369 208 0.136
Zebrafish
positive regulation of muscle tissue development GO:1901863 1 0.136
ventral spinal cord development GO:0021517 35 0.134
regulation of bmp signaling pathway GO:0030510 39 0.134
floor plate development GO:0033504 15 0.133
locomotion GO:0040011 313 0.132
Mouse
cellular response to chemical stimulus GO:0070887 157 0.131
chordate embryonic development GO:0043009 271 0.131
positive regulation of striated muscle cell differentiation GO:0051155 1 0.129
mesenchymal cell proliferation GO:0010463 1 0.129
Mouse
embryonic digestive tract development GO:0048566 4 0.129
muscle cell fate determination GO:0007521 1 0.128
cellular component movement GO:0006928 335 0.127
Mouse
specification of organ identity GO:0010092 2 0.127
antimicrobial humoral response GO:0019730 2 0.124
programmed cell death GO:0012501 119 0.123
Mouse Fly
angiogenesis GO:0001525 158 0.123
Zebrafish
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.122
cell migration to the midline involved in heart development GO:0003318 12 0.121
embryonic digestive tract morphogenesis GO:0048557 3 0.120
skeletal muscle tissue development GO:0007519 67 0.119
phagocytosis GO:0006909 3 0.119
cell projection morphogenesis GO:0048858 244 0.119
Fly
regulation of locomotion GO:0040012 55 0.118
muscle tissue development GO:0060537 110 0.117
cell differentiation in spinal cord GO:0021515 40 0.116
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.116
larval development GO:0002164 2 0.116
Worm Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.116
neuron fate specification GO:0048665 20 0.115
multicellular organism reproduction GO:0032504 35 0.115
positive regulation of developmental process GO:0051094 50 0.115
Zebrafish Mouse
cardiac atrium development GO:0003230 4 0.114
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.113
tissue remodeling GO:0048771 4 0.113
negative regulation of gene expression GO:0010629 65 0.113
regulation of signal transduction GO:0009966 225 0.112
Mouse
ear development GO:0043583 127 0.111
Zebrafish
negative regulation of leukocyte chemotaxis GO:0002689 3 0.110
positive regulation of neuron migration GO:2001224 2 0.109
growth GO:0040007 174 0.107
response to external stimulus GO:0009605 264 0.105
negative regulation of signaling GO:0023057 96 0.105
regulation of heart growth GO:0060420 2 0.104
bmp signaling pathway GO:0030509 52 0.104
gland development GO:0048732 143 0.104
limb morphogenesis GO:0035108 7 0.102
Mouse
myotube differentiation GO:0014902 45 0.101
inner ear receptor cell differentiation GO:0060113 29 0.101
Zebrafish
angioblast cell differentiation GO:0035779 2 0.101
regulation of organ growth GO:0046620 3 0.100
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.100
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.099
Zebrafish Mouse
negative regulation of striated muscle tissue development GO:0045843 2 0.097
peptide metabolic process GO:0006518 1 0.096
skeletal muscle organ development GO:0060538 78 0.096
nephron tubule morphogenesis GO:0072078 1 0.096
liver development GO:0001889 96 0.095
neuroepithelial cell differentiation GO:0060563 26 0.093
axonogenesis GO:0007409 152 0.093
negative regulation of cell differentiation GO:0045596 46 0.093
Zebrafish Mouse
cardiac chamber morphogenesis GO:0003206 12 0.092
Mouse
cartilage morphogenesis GO:0060536 13 0.091
Mouse
diencephalon development GO:0021536 58 0.091
cardioblast migration to the midline involved in heart rudiment formation GO:0003319 5 0.090
atrial cardiac muscle cell differentiation GO:0055011 5 0.090
enzyme linked receptor protein signaling pathway GO:0007167 106 0.090
mesoderm formation GO:0001707 43 0.089
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.088
Zebrafish
nephron tubule epithelial cell differentiation GO:0072160 1 0.088
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.088
regulation of muscle tissue development GO:1901861 6 0.088
axon development GO:0061564 166 0.087
Zebrafish
negative regulation of cellular biosynthetic process GO:0031327 55 0.086
periodic partitioning GO:0007365 1 0.085
negative regulation of myeloid cell differentiation GO:0045638 1 0.085
cell surface receptor signaling pathway GO:0007166 325 0.085
Mouse
cardiac muscle tissue morphogenesis GO:0055008 7 0.084
pectoral fin development GO:0033339 50 0.084
response to inorganic substance GO:0010035 38 0.083
regulation of mesenchymal cell proliferation GO:0010464 1 0.083
renal system vasculature development GO:0061437 2 0.083
somatic muscle development GO:0007525 4 0.083
pronephros development GO:0048793 69 0.082
cell proliferation involved in heart morphogenesis GO:0061323 2 0.081
Mouse
alcohol biosynthetic process GO:0046165 2 0.081
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.080
nephron epithelium morphogenesis GO:0072088 1 0.080
leukocyte differentiation GO:0002521 25 0.080
negative regulation of nucleic acid templated transcription GO:1903507 45 0.079
cardiocyte differentiation GO:0035051 44 0.079
positive regulation of cellular metabolic process GO:0031325 94 0.079
Human Zebrafish Mouse Fly
connective tissue development GO:0061448 99 0.077
Mouse
rhombomere 4 development GO:0021570 5 0.076
axis specification GO:0009798 43 0.076
regulation of skeletal muscle fiber development GO:0048742 2 0.076
chemotaxis GO:0006935 104 0.076
regulation of tube size GO:0035150 2 0.076
endodermal cell differentiation GO:0035987 19 0.075
photoreceptor cell fate specification GO:0043704 1 0.074
regulation of multicellular organism growth GO:0040014 4 0.074
extracellular matrix organization GO:0030198 27 0.074
positive regulation of muscle cell differentiation GO:0051149 1 0.073
multi organism reproductive process GO:0044703 36 0.073
megakaryocyte differentiation GO:0030219 1 0.073
dorsal aorta morphogenesis GO:0035912 3 0.072
positive regulation of multicellular organismal process GO:0051240 52 0.072
Zebrafish Mouse
renal system vasculature morphogenesis GO:0061438 1 0.072
motor neuron axon guidance GO:0008045 23 0.071
single organism biosynthetic process GO:0044711 71 0.071
regulation of cartilage development GO:0061035 7 0.070
post embryonic foregut morphogenesis GO:0048618 3 0.070
positive regulation of striated muscle tissue development GO:0045844 1 0.070
negative regulation of cell communication GO:0010648 96 0.070
nerve development GO:0021675 45 0.070
Zebrafish
negative regulation of muscle tissue development GO:1901862 2 0.070
retinal rod cell development GO:0046548 4 0.069
craniofacial suture morphogenesis GO:0097094 2 0.069
camera type eye morphogenesis GO:0048593 108 0.069
Zebrafish
retinal metabolic process GO:0042574 3 0.069
aorta morphogenesis GO:0035909 3 0.069
negative regulation of signal transduction GO:0009968 94 0.069
ameboidal type cell migration GO:0001667 143 0.069
Mouse
apoptotic process involved in morphogenesis GO:0060561 2 0.068
Mouse
heart rudiment formation GO:0003315 5 0.068
post anal tail morphogenesis GO:0036342 19 0.068
camera type eye development GO:0043010 222 0.067
Zebrafish
mesendoderm development GO:0048382 10 0.066
forebrain regionalization GO:0021871 4 0.065
response to fluid shear stress GO:0034405 2 0.065
cellular response to retinoic acid GO:0071300 1 0.064
cranial nerve development GO:0021545 42 0.064
Zebrafish
neuron migration GO:0001764 22 0.063
response to other organism GO:0051707 97 0.062
glomerulus morphogenesis GO:0072102 7 0.062
myeloid cell homeostasis GO:0002262 56 0.062
Zebrafish
intracellular signal transduction GO:0035556 85 0.061
macrophage differentiation GO:0030225 7 0.060
dorsal ventral neural tube patterning GO:0021904 1 0.060
cardiac muscle cell proliferation GO:0060038 5 0.059
regulation of cellular component organization GO:0051128 86 0.058
glial cell migration GO:0008347 3 0.058
protein metabolic process GO:0019538 183 0.057
exocrine system development GO:0035272 28 0.057
Zebrafish
response to biotic stimulus GO:0009607 97 0.056
epithelial cell differentiation GO:0030855 116 0.055
regulation of cell death GO:0010941 103 0.055
Mouse Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.055
Human Zebrafish Mouse Fly
nephric duct development GO:0072176 13 0.054
organelle organization GO:0006996 227 0.053
eye morphogenesis GO:0048592 144 0.052
Zebrafish
endoderm formation GO:0001706 29 0.051
ectodermal placode formation GO:0060788 26 0.051
regulation of vasculature development GO:1901342 33 0.050
megakaryocyte development GO:0035855 1 0.050
neuron projection development GO:0031175 180 0.050
Zebrafish Fly
regulation of stem cell differentiation GO:2000736 4 0.050
wnt signaling pathway GO:0016055 80 0.050
extracellular structure organization GO:0043062 27 0.050
venous blood vessel development GO:0060841 9 0.050
positive chemotaxis GO:0050918 5 0.049
induction of positive chemotaxis GO:0050930 4 0.049
negative regulation of leukocyte differentiation GO:1902106 1 0.048
hepaticobiliary system development GO:0061008 98 0.048
cell fate commitment GO:0045165 99 0.047
Zebrafish
patterning of blood vessels GO:0001569 15 0.047
negative regulation of metabolic process GO:0009892 86 0.047
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.047
locus ceruleus development GO:0021703 3 0.047
vasculature development GO:0001944 278 0.047
Zebrafish Mouse
semicircular canal morphogenesis GO:0048752 18 0.047
regulation of biomineral tissue development GO:0070167 2 0.047
hindbrain development GO:0030902 91 0.046
Zebrafish
negative regulation of biological process GO:0048519 304 0.045
Zebrafish Mouse Fly
stem cell proliferation GO:0072089 4 0.045
Mouse
monocyte differentiation GO:0030224 2 0.045
regulation of cell projection assembly GO:0060491 4 0.044
patterning of lymph vessels GO:0060854 1 0.044
regulation of behavior GO:0050795 24 0.044
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.044
regulation of dna templated transcription elongation GO:0032784 3 0.043
Fly
neuron projection guidance GO:0097485 86 0.043
kupffer s vesicle development GO:0070121 50 0.043
neuron fate commitment GO:0048663 26 0.043
Zebrafish
septum transversum development GO:0003343 4 0.043
cellular response to external stimulus GO:0071496 2 0.042
protein localization to nucleus GO:0034504 3 0.042
cardiac cell fate commitment GO:0060911 1 0.042
regulation of neuron migration GO:2001222 2 0.042
hormone metabolic process GO:0042445 19 0.042
regulation of endothelial cell proliferation GO:0001936 1 0.042
positive regulation of cell motility GO:2000147 11 0.042
cardiac chamber development GO:0003205 19 0.041
Mouse
negative regulation of cardiac muscle tissue development GO:0055026 1 0.040
atrial cardiac muscle cell development GO:0055014 4 0.040
blood circulation GO:0008015 87 0.040
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.040
negative regulation of cell death GO:0060548 60 0.039
Mouse Fly
rostrocaudal neural tube patterning GO:0021903 29 0.039
endothelial cell proliferation GO:0001935 11 0.039
regulation of skeletal muscle cell differentiation GO:2001014 1 0.039
positive regulation of response to stimulus GO:0048584 80 0.039
Mouse
somatic motor neuron differentiation GO:0021523 5 0.039
anterior posterior axis specification GO:0009948 20 0.039
central nervous system neuron differentiation GO:0021953 74 0.038
Zebrafish
limbic system development GO:0021761 16 0.038
regulation of striated muscle tissue development GO:0016202 6 0.038
anal fin development GO:0033335 1 0.038
digestive system process GO:0022600 9 0.038
kidney epithelium development GO:0072073 23 0.038
glomerulus vasculature morphogenesis GO:0072103 1 0.037
lymph vessel development GO:0001945 27 0.037

hand2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.238
physical disorder DOID:0080015 0 0.060
cardiovascular system disease DOID:1287 0 0.043