Danio rerio

0 known processes

LOC556453

zinc finger homeobox protein 4-like

LOC556453 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.117
neuron differentiation GO:0030182 353 0.117
central nervous system development GO:0007417 387 0.106
neuron neuron synaptic transmission GO:0007270 1 0.099
head development GO:0060322 303 0.097
generation of neurons GO:0048699 385 0.088
post embryonic organ development GO:0048569 4 0.088
immune system process GO:0002376 241 0.087
locomotion GO:0040011 313 0.084
brain development GO:0007420 293 0.083
glial cell migration GO:0008347 3 0.083
eye development GO:0001654 277 0.078
cellular component movement GO:0006928 335 0.074
cell projection morphogenesis GO:0048858 244 0.074
cell surface receptor signaling pathway GO:0007166 325 0.070
blood vessel morphogenesis GO:0048514 216 0.069
cell morphogenesis involved in differentiation GO:0000904 195 0.066
camera type eye development GO:0043010 222 0.062
cell substrate adhesion GO:0031589 4 0.062
larval development GO:0002164 2 0.061
immune system development GO:0002520 191 0.061
establishment of localization GO:0051234 244 0.060
positive regulation of transport GO:0051050 2 0.059
neuron projection morphogenesis GO:0048812 161 0.055
sensory organ development GO:0007423 393 0.054
cell morphogenesis GO:0000902 289 0.053
aging GO:0007568 2 0.053
meiotic nuclear division GO:0007126 4 0.052
regulation of reproductive process GO:2000241 4 0.052
regulation of metabolic process GO:0019222 359 0.051
cell motility GO:0048870 244 0.051
negative regulation of cellular process GO:0048523 283 0.050
regulation of macromolecule biosynthetic process GO:0010556 225 0.050
positive regulation of biological process GO:0048518 253 0.048
adult behavior GO:0030534 2 0.047
regulation of response to stimulus GO:0048583 269 0.047
gtp metabolic process GO:0046039 4 0.046
negative regulation of biological process GO:0048519 304 0.044
gene expression GO:0010467 252 0.043
neuron development GO:0048666 262 0.042
positive regulation of cellular component biogenesis GO:0044089 3 0.041
regulation of primary metabolic process GO:0080090 311 0.040
morphogenesis of an epithelium GO:0002009 333 0.039
guanosine containing compound metabolic process GO:1901068 4 0.039
regulation of multicellular organismal development GO:2000026 223 0.039
response to carbohydrate GO:0009743 3 0.038
response to chemical GO:0042221 320 0.038
synaptic target recognition GO:0008039 1 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.038
embryonic organ development GO:0048568 381 0.038
muscle cell differentiation GO:0042692 139 0.037
cell part morphogenesis GO:0032990 246 0.037
regulation of establishment of protein localization GO:0070201 4 0.037
cognition GO:0050890 1 0.036
female gonad development GO:0008585 4 0.035
notochord development GO:0030903 54 0.035
development of primary female sexual characteristics GO:0046545 4 0.035
embryonic organ morphogenesis GO:0048562 274 0.035
cellular macromolecule metabolic process GO:0044260 391 0.034
cellular component morphogenesis GO:0032989 336 0.034
hematopoietic or lymphoid organ development GO:0048534 191 0.034
response to organic substance GO:0010033 153 0.034
regulation of protein transport GO:0051223 3 0.033
multicellular organism growth GO:0035264 4 0.033
neuron projection development GO:0031175 180 0.033
gtp catabolic process GO:0006184 2 0.033
phagocytosis GO:0006909 3 0.033
central nervous system neuron differentiation GO:0021953 74 0.032
regulation of rna metabolic process GO:0051252 224 0.031
guanosine containing compound catabolic process GO:1901069 2 0.031
cell migration GO:0016477 237 0.031
transcription from rna polymerase ii promoter GO:0006366 80 0.030
vasculature development GO:0001944 278 0.030
positive regulation of cellular process GO:0048522 201 0.029
regionalization GO:0003002 274 0.029
blood vessel development GO:0001568 246 0.029
response to external stimulus GO:0009605 264 0.029
heart development GO:0007507 313 0.028
system process GO:0003008 185 0.028
regulation of multicellular organismal process GO:0051239 277 0.028
regulation of intracellular protein transport GO:0033157 3 0.027
urogenital system development GO:0001655 97 0.026
regulation of gene expression GO:0010468 265 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
tube morphogenesis GO:0035239 349 0.026
branching morphogenesis of a nerve GO:0048755 4 0.026
single organism metabolic process GO:0044710 217 0.026
cellular component assembly GO:0022607 170 0.025
camera type eye morphogenesis GO:0048593 108 0.025
maintenance of location GO:0051235 4 0.025
regulation of dendrite development GO:0050773 3 0.025
nitrogen compound metabolic process GO:0006807 319 0.025
axonogenesis GO:0007409 152 0.025
negative regulation of protein kinase activity GO:0006469 4 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.024
regulation of gtp catabolic process GO:0033124 2 0.024
localization of cell GO:0051674 244 0.024
response to monosaccharide GO:0034284 3 0.024
digestive system development GO:0055123 289 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
cellular ketone metabolic process GO:0042180 11 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
organelle assembly GO:0070925 110 0.023
multicellular organismal signaling GO:0035637 22 0.022
sensory organ morphogenesis GO:0090596 200 0.022
developmental cell growth GO:0048588 52 0.022
stem cell maintenance GO:0019827 4 0.022
response to glucose GO:0009749 3 0.022
regulation of protein catabolic process GO:0042176 1 0.022
stem cell proliferation GO:0072089 4 0.022
lipid storage GO:0019915 1 0.022
forebrain development GO:0030900 96 0.022
axon guidance GO:0007411 86 0.021
organelle organization GO:0006996 227 0.021
neuron projection extension GO:1990138 45 0.021
axon development GO:0061564 166 0.021
oxoacid metabolic process GO:0043436 31 0.021
response to alkaloid GO:0043279 2 0.021
regulation of gtpase activity GO:0043087 2 0.021
transcription dna templated GO:0006351 181 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
regulation of mrna splicing via spliceosome GO:0048024 3 0.021
kidney development GO:0001822 92 0.021
central nervous system neuron axonogenesis GO:0021955 18 0.021
positive regulation of cell cycle GO:0045787 3 0.021
axon extension GO:0048675 45 0.021
negative regulation of signaling GO:0023057 96 0.020
cell adhesion GO:0007155 40 0.020
protein import into nucleus GO:0006606 3 0.020
cellular component biogenesis GO:0044085 178 0.020
regulation of biological quality GO:0065008 263 0.020
protein import GO:0017038 3 0.020
regulation of meiotic cell cycle GO:0051445 1 0.020
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.020
negative regulation of reproductive process GO:2000242 3 0.020
dopaminergic neuron differentiation GO:0071542 14 0.020
lipid homeostasis GO:0055088 3 0.019
germ line stem cell maintenance GO:0030718 2 0.019
cell matrix adhesion GO:0007160 4 0.018
compound eye development GO:0048749 2 0.018
pronephros development GO:0048793 69 0.018
regulation of transmembrane transporter activity GO:0022898 2 0.018
response to inorganic substance GO:0010035 38 0.018
cell proliferation in hindbrain GO:0021534 4 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
female sex differentiation GO:0046660 4 0.018
cellular biosynthetic process GO:0044249 286 0.018
regulation of cellular metabolic process GO:0031323 320 0.017
regulation of developmental process GO:0050793 247 0.017
positive regulation of catabolic process GO:0009896 4 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of transcription dna templated GO:0006355 213 0.017
regulation of cytokine production GO:0001817 3 0.017
eye morphogenesis GO:0048592 144 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
neurological system process GO:0050877 62 0.017
membrane invagination GO:0010324 1 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
embryonic skeletal joint development GO:0072498 3 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
protein metabolic process GO:0019538 183 0.017
alternative mrna splicing via spliceosome GO:0000380 1 0.017
developmental growth GO:0048589 166 0.017
stem cell division GO:0017145 1 0.017
fertilization GO:0009566 3 0.016
protein secretion GO:0009306 1 0.016
neuron projection guidance GO:0097485 86 0.016
biological adhesion GO:0022610 40 0.016
regulation of cell substrate adhesion GO:0010810 1 0.016
cellular protein metabolic process GO:0044267 129 0.016
chemotaxis GO:0006935 104 0.016
skeletal system development GO:0001501 181 0.016
spermatid development GO:0007286 2 0.016
multicellular organismal response to stress GO:0033555 2 0.016
lymph vessel development GO:0001945 27 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
nuclear import GO:0051170 3 0.016
transport GO:0006810 220 0.016
muscle structure development GO:0061061 196 0.016
regulation of metal ion transport GO:0010959 4 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
response to hexose GO:0009746 3 0.016
cell projection organization GO:0030030 284 0.016
hemopoiesis GO:0030097 183 0.016
striated muscle cell differentiation GO:0051146 129 0.015
response to abiotic stimulus GO:0009628 122 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
amine metabolic process GO:0009308 2 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
regulation of protein complex assembly GO:0043254 3 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
protein localization to nucleus GO:0034504 3 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
protein targeting to nucleus GO:0044744 3 0.015
angiogenesis GO:0001525 158 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
actin filament based process GO:0030029 64 0.014
central nervous system projection neuron axonogenesis GO:0021952 15 0.014
forebrain cell migration GO:0021885 1 0.014
positive regulation of secretion GO:0051047 1 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
regulation of synapse assembly GO:0051963 3 0.014
phagocytosis engulfment GO:0006911 1 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
gland development GO:0048732 143 0.014
digestive tract morphogenesis GO:0048546 231 0.014
somatic muscle development GO:0007525 4 0.014
anterior posterior pattern specification GO:0009952 152 0.014
embryonic skeletal system morphogenesis GO:0048704 93 0.014
cellular amine metabolic process GO:0044106 2 0.014
regulation of programmed cell death GO:0043067 101 0.014
muscle tissue development GO:0060537 110 0.014
meiotic cell cycle process GO:1903046 3 0.014
single organism reproductive process GO:0044702 40 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
negative regulation of kinase activity GO:0033673 4 0.014
negative regulation of cell communication GO:0010648 96 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
membrane fusion GO:0061025 2 0.014
negative regulation of developmental process GO:0051093 65 0.014
negative regulation of cell differentiation GO:0045596 46 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
regulation of cell activation GO:0050865 1 0.014
cellular protein catabolic process GO:0044257 4 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
small molecule metabolic process GO:0044281 77 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
response to drug GO:0042493 3 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
cell proliferation GO:0008283 80 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of transporter activity GO:0032409 2 0.013
lateral inhibition GO:0046331 1 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
renal system development GO:0072001 94 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
growth GO:0040007 174 0.013
regulation of signaling GO:0023051 235 0.013
multi organism process GO:0051704 134 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regulation of signal transduction GO:0009966 225 0.013
cellular response to starvation GO:0009267 1 0.013
rna localization GO:0006403 4 0.013
larval heart development GO:0007508 2 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
neuroblast proliferation GO:0007405 2 0.013
g protein coupled receptor signaling pathway GO:0007186 74 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
peripheral nervous system neuron development GO:0048935 22 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
positive regulation of cytokine production GO:0001819 2 0.013
regulation of myotube differentiation GO:0010830 2 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
organic substance biosynthetic process GO:1901576 289 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
bmp signaling pathway GO:0030509 52 0.013
ear development GO:0043583 127 0.013
negative chemotaxis GO:0050919 1 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
single organism organelle organization GO:1902589 199 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
regulation of mrna processing GO:0050684 3 0.012
cilium assembly GO:0042384 58 0.012
secondary metabolic process GO:0019748 3 0.012
organic acid metabolic process GO:0006082 31 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
regulation of calcium ion transport GO:0051924 2 0.012
cellular response to external stimulus GO:0071496 2 0.012
gastrulation GO:0007369 208 0.012
neural crest cell development GO:0014032 62 0.012
regulation of ras gtpase activity GO:0032318 2 0.012
rna biosynthetic process GO:0032774 181 0.012
cell cell signaling GO:0007267 52 0.012
regulation of cell communication GO:0010646 232 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
regulation of protein targeting GO:1903533 2 0.012
response to uv GO:0009411 3 0.012
cellular amide metabolic process GO:0043603 4 0.012
regulation of blood pressure GO:0008217 1 0.012
regulation of cell differentiation GO:0045595 142 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
macromolecule modification GO:0043412 111 0.012
spermatid differentiation GO:0048515 2 0.012
determination of bilateral symmetry GO:0009855 204 0.012
microtubule organizing center organization GO:0031023 1 0.012
peripheral nervous system development GO:0007422 55 0.012
mononuclear cell proliferation GO:0032943 1 0.012
midbrain development GO:0030901 28 0.012
positive regulation of cell adhesion GO:0045785 1 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
wound healing GO:0042060 90 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
protein targeting to membrane GO:0006612 1 0.011
negative regulation of axon guidance GO:1902668 1 0.011
regulation of nervous system development GO:0051960 90 0.011
nuclear transport GO:0051169 4 0.011
specification of symmetry GO:0009799 204 0.011
oocyte maturation GO:0001556 4 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
synaptic transmission cholinergic GO:0007271 4 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
chordate embryonic development GO:0043009 271 0.011
protein processing GO:0016485 12 0.011
neuronal action potential GO:0019228 18 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
organic cyclic compound metabolic process GO:1901360 301 0.011
axon midline choice point recognition GO:0016199 4 0.011
behavior GO:0007610 74 0.011
nucleic acid metabolic process GO:0090304 244 0.011
cytoskeleton organization GO:0007010 96 0.011
extracellular structure organization GO:0043062 27 0.011
rna metabolic process GO:0016070 219 0.011
response to hydrogen peroxide GO:0042542 3 0.011
determination of left right symmetry GO:0007368 179 0.010
phosphorus metabolic process GO:0006793 109 0.010
actin filament based movement GO:0030048 1 0.010
sensory perception of pain GO:0019233 1 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010
positive regulation of translation GO:0045727 1 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
muscle cell development GO:0055001 115 0.010
response to light stimulus GO:0009416 46 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
mitochondrion organization GO:0007005 4 0.010
primary neural tube formation GO:0014020 1 0.010
establishment of protein localization to organelle GO:0072594 4 0.010
single organism localization GO:1902578 225 0.010
regulation of inflammatory response GO:0050727 2 0.010
regulation of blood vessel size GO:0050880 2 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
cellular amino acid metabolic process GO:0006520 7 0.010
kupffer s vesicle development GO:0070121 50 0.010
peptidyl serine modification GO:0018209 2 0.010
cellular protein modification process GO:0006464 100 0.010
response to stress GO:0006950 263 0.010
negative regulation of catabolic process GO:0009895 3 0.010

LOC556453 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
musculoskeletal system disease DOID:17 0 0.027
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
nervous system disease DOID:863 0 0.012
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011