Danio rerio

0 known processes

hoxa5a

homeo box A5a

(Aliases: z-1)

hoxa5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage development GO:0048736 80 0.875
Zebrafish
fin morphogenesis GO:0033334 53 0.852
Zebrafish
skeletal system development GO:0001501 181 0.840
Mouse
appendage morphogenesis GO:0035107 56 0.779
Zebrafish
posterior lateral line neuromast primordium migration GO:0048920 12 0.703
Zebrafish
rna metabolic process GO:0016070 219 0.693
Human Mouse
central nervous system development GO:0007417 387 0.645
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.612
Human Mouse
mechanosensory lateral line system development GO:0048881 49 0.603
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.597
Human Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.564
Mouse
embryonic organ morphogenesis GO:0048562 274 0.561
Mouse
fin development GO:0033333 77 0.558
Zebrafish
embryonic organ development GO:0048568 381 0.553
Mouse
pectoral fin morphogenesis GO:0035138 29 0.539
Zebrafish
pectoral fin development GO:0033339 50 0.533
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.527
Human Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.517
Human Mouse
head development GO:0060322 303 0.511
Zebrafish
embryonic pectoral fin morphogenesis GO:0035118 24 0.510
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.493
Human Mouse
regionalization GO:0003002 274 0.481
Mouse
regulation of cellular metabolic process GO:0031323 320 0.461
Human Mouse
brain development GO:0007420 293 0.430
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.430
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.394
Mouse
cellular biosynthetic process GO:0044249 286 0.393
Human Mouse
nucleic acid metabolic process GO:0090304 244 0.353
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.350
Human Mouse
regulation of biosynthetic process GO:0009889 250 0.336
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.331
Human Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.320
Human Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.319
Human Mouse
positive regulation of rna metabolic process GO:0051254 59 0.313
Human Mouse
regulation of gene expression GO:0010468 265 0.308
Human Mouse
skeletal system morphogenesis GO:0048705 102 0.297
Mouse
exocrine pancreas development GO:0031017 28 0.288
Zebrafish
sensory system development GO:0048880 76 0.280
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.277
Human Mouse
anterior posterior pattern specification GO:0009952 152 0.276
Mouse
chordate embryonic development GO:0043009 271 0.275
Mouse
posterior lateral line development GO:0048916 38 0.268
Zebrafish
regulation of epithelial cell proliferation GO:0050678 3 0.266
Mouse
regulation of transcription dna templated GO:0006355 213 0.260
Human Mouse
lateral line development GO:0048882 66 0.258
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.258
Human Mouse
rna biosynthetic process GO:0032774 181 0.253
Human Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.246
Human Mouse
neuromast primordium migration GO:0048883 12 0.239
Zebrafish
embryonic skeletal system development GO:0048706 97 0.238
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.233
Human Mouse
regulation of rna biosynthetic process GO:2001141 213 0.226
Human Mouse
nucleic acid templated transcription GO:0097659 181 0.222
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.213
Human Mouse
digestive system development GO:0055123 289 0.193
Zebrafish Mouse
cartilage development GO:0051216 96 0.188
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.183
Human Mouse
cell fate specification GO:0001708 68 0.181
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.176
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.173
Human Mouse
heart development GO:0007507 313 0.171
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.171
Human Mouse
embryonic viscerocranium morphogenesis GO:0048703 52 0.166
heterocycle metabolic process GO:0046483 290 0.159
Human Mouse
gene expression GO:0010467 252 0.157
Human Mouse
embryonic appendage morphogenesis GO:0035113 30 0.155
Zebrafish
posterior lateral line system development GO:0048915 46 0.154
Zebrafish
pancreas development GO:0031016 84 0.151
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.144
Human Mouse
regulation of metabolic process GO:0019222 359 0.140
Human Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.140
regulation of stem cell proliferation GO:0072091 2 0.139
regulation of multicellular organism growth GO:0040014 4 0.139
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.137
macromolecule biosynthetic process GO:0009059 227 0.134
Human Mouse
regulation of cell differentiation GO:0045595 142 0.132
Human
positive regulation of cellular process GO:0048522 201 0.123
Human Mouse
transcription dna templated GO:0006351 181 0.122
Human Mouse
stem cell differentiation GO:0048863 117 0.122
Zebrafish
biosynthetic process GO:0009058 294 0.116
Human Mouse
nitrogen compound metabolic process GO:0006807 319 0.115
Human Mouse
positive regulation of gene expression GO:0010628 71 0.112
Human Mouse
negative regulation of cellular process GO:0048523 283 0.112
Human
rhombomere 4 development GO:0021570 5 0.105
apoptotic process involved in development GO:1902742 2 0.100
negative regulation of nucleic acid templated transcription GO:1903507 45 0.097
negative regulation of macromolecule metabolic process GO:0010605 76 0.093
stem cell division GO:0017145 1 0.092
negative regulation of gene expression GO:0010629 65 0.089
developmental programmed cell death GO:0010623 4 0.089
facial nerve development GO:0021561 3 0.085
positive regulation of biosynthetic process GO:0009891 68 0.084
Human Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.082
primary neural tube formation GO:0014020 1 0.082
embryonic cranial skeleton morphogenesis GO:0048701 90 0.082
negative regulation of biological process GO:0048519 304 0.079
Human
skeletal muscle organ development GO:0060538 78 0.075
cell motility GO:0048870 244 0.071
Zebrafish Mouse
neural keel formation GO:0014025 1 0.070
positive regulation of transcription dna templated GO:0045893 57 0.068
Human Mouse
cellular ketone metabolic process GO:0042180 11 0.067
cell migration in hindbrain GO:0021535 7 0.066
regulation of primary metabolic process GO:0080090 311 0.062
Human Mouse
generation of neurons GO:0048699 385 0.062
immune system process GO:0002376 241 0.061
Human
cell fate commitment GO:0045165 99 0.060
Zebrafish
cardiocyte differentiation GO:0035051 44 0.059
Zebrafish
homeostatic process GO:0042592 142 0.056
Human
regulation of mesenchymal cell proliferation GO:0010464 1 0.054
ventricular system development GO:0021591 12 0.054
establishment of protein localization to organelle GO:0072594 4 0.054
regulation of biological quality GO:0065008 263 0.054
Human
regulation of macromolecule metabolic process GO:0060255 317 0.053
Human Mouse
negative regulation of transcription dna templated GO:0045892 45 0.050
positive regulation of epithelial cell proliferation GO:0050679 1 0.050
blood circulation GO:0008015 87 0.050
rhombomere 4 morphogenesis GO:0021661 5 0.050
sensory organ development GO:0007423 393 0.049
cellular macromolecule biosynthetic process GO:0034645 224 0.048
Human Mouse
exocrine system development GO:0035272 28 0.048
Zebrafish
cell substrate adhesion GO:0031589 4 0.048
cell migration GO:0016477 237 0.047
Zebrafish Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.047
Human Mouse
negative regulation of metabolic process GO:0009892 86 0.047
homeostasis of number of cells GO:0048872 62 0.046
Human
cell death GO:0008219 121 0.046
Human
regulation of protein transport GO:0051223 3 0.046
regulation of developmental process GO:0050793 247 0.046
Human Mouse
endocrine pancreas development GO:0031018 27 0.046
Zebrafish
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.046
positive regulation of biological process GO:0048518 253 0.045
Human Mouse
myotube differentiation GO:0014902 45 0.045
facial nucleus development GO:0021754 7 0.043
stem cell proliferation GO:0072089 4 0.043
cellular aromatic compound metabolic process GO:0006725 295 0.042
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.042
Human Mouse
epithelial cell differentiation GO:0030855 116 0.041
Mouse
heart morphogenesis GO:0003007 156 0.041
cellular component movement GO:0006928 335 0.041
Zebrafish Mouse
single organism metabolic process GO:0044710 217 0.041
regulation of cell communication GO:0010646 232 0.040
multicellular organism growth GO:0035264 4 0.040
Mouse
establishment of localization GO:0051234 244 0.040
lateral line system development GO:0048925 76 0.040
Zebrafish
regulation of multicellular organismal development GO:2000026 223 0.040
Human Mouse
neuron fate specification GO:0048665 20 0.039
locomotion GO:0040011 313 0.039
Zebrafish Mouse
positive regulation of nucleic acid templated transcription GO:1903508 57 0.038
Human Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.038
Human Mouse
blood vessel development GO:0001568 246 0.038
Human
endocrine system development GO:0035270 65 0.038
Zebrafish Mouse
negative regulation of cellular metabolic process GO:0031324 77 0.038
cell proliferation GO:0008283 80 0.037
Zebrafish Mouse
programmed cell death GO:0012501 119 0.036
Human
carboxylic acid metabolic process GO:0019752 22 0.036
positive regulation of transport GO:0051050 2 0.036
striated muscle cell differentiation GO:0051146 129 0.035
mesoderm development GO:0007498 88 0.035
camera type eye development GO:0043010 222 0.034
embryonic limb morphogenesis GO:0030326 2 0.033
single organism nuclear import GO:1902593 3 0.033
amine metabolic process GO:0009308 2 0.033
connective tissue development GO:0061448 99 0.032
Mouse
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.032
ear development GO:0043583 127 0.032
muscle cell differentiation GO:0042692 139 0.032
epidermis development GO:0008544 48 0.031
circulatory system process GO:0003013 87 0.031
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.031
transcription from rna polymerase ii promoter GO:0006366 80 0.031
Human Mouse
nucleocytoplasmic transport GO:0006913 4 0.031
cellular protein catabolic process GO:0044257 4 0.031
regulation of inflammatory response GO:0050727 2 0.030
hindbrain development GO:0030902 91 0.030
signal transduction GO:0007165 455 0.030
regulation of wnt signaling pathway GO:0030111 53 0.030
regulation of stem cell differentiation GO:2000736 4 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.029
Human Mouse
mesenchymal cell proliferation GO:0010463 1 0.029
forebrain anterior posterior pattern specification GO:0021797 3 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
aging GO:0007568 2 0.029
hemopoiesis GO:0030097 183 0.029
Human
muscle structure development GO:0061061 196 0.029
hematopoietic or lymphoid organ development GO:0048534 191 0.028
Human
negative regulation of biosynthetic process GO:0009890 55 0.027
negative regulation of cell differentiation GO:0045596 46 0.027
Human
oxoacid metabolic process GO:0043436 31 0.027
modification dependent macromolecule catabolic process GO:0043632 3 0.027
regulation of nucleocytoplasmic transport GO:0046822 2 0.027
embryonic heart tube morphogenesis GO:0003143 108 0.027
definitive hemopoiesis GO:0060216 18 0.026
muscle fiber development GO:0048747 52 0.026
protein stabilization GO:0050821 2 0.026
embryonic heart tube development GO:0035050 133 0.026
regulation of cytoplasmic transport GO:1903649 4 0.026
meiotic nuclear division GO:0007126 4 0.025
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
negative regulation of developmental process GO:0051093 65 0.025
Human
epidermal cell differentiation GO:0009913 36 0.025
positive regulation of cell death GO:0010942 29 0.025
Human
cardioblast differentiation GO:0010002 9 0.025
Zebrafish
erythrocyte homeostasis GO:0034101 55 0.025
Human
negative regulation of myeloid cell differentiation GO:0045638 1 0.025
Human
retina development in camera type eye GO:0060041 146 0.025
larval development GO:0002164 2 0.024
organic acid metabolic process GO:0006082 31 0.024
regulation of response to stimulus GO:0048583 269 0.024
central nervous system neuron differentiation GO:0021953 74 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.024
positive regulation of metabolic process GO:0009893 108 0.023
Human Mouse
eye morphogenesis GO:0048592 144 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
muscle tissue development GO:0060537 110 0.023
positive regulation of cell cycle GO:0045787 3 0.023
apoptotic process involved in morphogenesis GO:0060561 2 0.022
tube closure GO:0060606 1 0.022
liver development GO:0001889 96 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
Mouse
immune system development GO:0002520 191 0.022
Human
regulation of skeletal muscle tissue development GO:0048641 4 0.021
negative regulation of rna biosynthetic process GO:1902679 45 0.021
regulation of molecular function GO:0065009 70 0.021
embryonic camera type eye morphogenesis GO:0048596 19 0.021
camera type eye morphogenesis GO:0048593 108 0.021
skeletal muscle tissue development GO:0007519 67 0.021
peripheral nervous system development GO:0007422 55 0.021
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
protein targeting to nucleus GO:0044744 3 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
localization of cell GO:0051674 244 0.020
Zebrafish Mouse
regulation of cell death GO:0010941 103 0.020
Human
maintenance of location GO:0051235 4 0.020
regulation of signal transduction GO:0009966 225 0.020
cranial nerve development GO:0021545 42 0.020
regulation of mrna splicing via spliceosome GO:0048024 3 0.020
stem cell maintenance GO:0019827 4 0.019
regulation of binding GO:0051098 3 0.019
membrane fusion GO:0061025 2 0.019
formation of primary germ layer GO:0001704 62 0.019
determination of heart left right asymmetry GO:0061371 117 0.019
hindbrain morphogenesis GO:0021575 22 0.019
positive regulation of developmental process GO:0051094 50 0.019
Human
regulation of nucleotide catabolic process GO:0030811 2 0.019
organelle organization GO:0006996 227 0.019
negative regulation of rna metabolic process GO:0051253 48 0.019
glial cell migration GO:0008347 3 0.019
developmental growth involved in morphogenesis GO:0060560 86 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
negative regulation of cellular biosynthetic process GO:0031327 55 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
negative regulation of defense response GO:0031348 2 0.018
rhombomere development GO:0021546 19 0.018
cell cycle g1 s phase transition GO:0044843 1 0.018
blood vessel morphogenesis GO:0048514 216 0.018
Human
positive regulation of cellular metabolic process GO:0031325 94 0.018
Human Mouse
modification dependent protein catabolic process GO:0019941 3 0.017
response to biotic stimulus GO:0009607 97 0.017
regulation of cytokine production GO:0001817 3 0.017
nuclear transport GO:0051169 4 0.017
keratinocyte differentiation GO:0030216 0 0.017
regulation of protein catabolic process GO:0042176 1 0.017
positive regulation of cell differentiation GO:0045597 30 0.017
Human
regulation of cell development GO:0060284 100 0.017
mesenchymal cell development GO:0014031 78 0.017
nuclear import GO:0051170 3 0.017
striated muscle cell development GO:0055002 108 0.017
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.017
regulation of gastrulation GO:0010470 24 0.016
positive regulation of epithelial cell differentiation GO:0030858 2 0.016
lipid storage GO:0019915 1 0.016
cellular amine metabolic process GO:0044106 2 0.016
vasculature development GO:0001944 278 0.016
Human
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
tube morphogenesis GO:0035239 349 0.016
Mouse
single organism biosynthetic process GO:0044711 71 0.016
eye development GO:0001654 277 0.016
mechanoreceptor differentiation GO:0042490 37 0.016
wnt signaling pathway GO:0016055 80 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
Human
positive regulation of catabolic process GO:0009896 4 0.015
cardiac atrium morphogenesis GO:0003209 2 0.015
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.015
chromatin organization GO:0006325 22 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
protein import into nucleus GO:0006606 3 0.015
negative regulation of signal transduction GO:0009968 94 0.015
bone development GO:0060348 14 0.015
positive regulation of programmed cell death GO:0043068 29 0.015
Human
renal tubule morphogenesis GO:0061333 1 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.014
mesoderm formation GO:0001707 43 0.014
response to stress GO:0006950 263 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
cranial nerve morphogenesis GO:0021602 15 0.014
positive regulation of endothelial cell proliferation GO:0001938 1 0.014
inner ear development GO:0048839 126 0.014
transmission of nerve impulse GO:0019226 19 0.014
specification of symmetry GO:0009799 204 0.014
mesenchyme development GO:0060485 127 0.013
Mouse
negative regulation of protein complex assembly GO:0031333 1 0.013
myotube cell development GO:0014904 35 0.013
developmental growth GO:0048589 166 0.013
proximal distal pattern formation GO:0009954 1 0.013
alternative mrna splicing via spliceosome GO:0000380 1 0.013
neuronal action potential GO:0019228 18 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
single organism organelle organization GO:1902589 199 0.013
protein import GO:0017038 3 0.013
regulation of synapse organization GO:0050807 3 0.013
negative regulation of signaling GO:0023057 96 0.013
chondrocyte development GO:0002063 4 0.013
peptide metabolic process GO:0006518 1 0.013
negative regulation of leukocyte differentiation GO:1902106 1 0.013
single organism cellular localization GO:1902580 46 0.013
mesenchymal cell differentiation GO:0048762 87 0.013
positive regulation of signaling GO:0023056 56 0.013
positive regulation of cell development GO:0010720 25 0.013
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.013
regulation of cell activation GO:0050865 1 0.013
response to other organism GO:0051707 97 0.012
nephron epithelium morphogenesis GO:0072088 1 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
post anal tail morphogenesis GO:0036342 19 0.012
regulation of protein targeting GO:1903533 2 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
skeletal muscle fiber development GO:0048741 35 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
autophagy GO:0006914 4 0.011
regulation of apoptotic process GO:0042981 98 0.011
Human
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
fertilization GO:0009566 3 0.011
regulation of catalytic activity GO:0050790 55 0.011
somitogenesis GO:0001756 87 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
pharyngeal system development GO:0060037 18 0.011
negative regulation of wnt signaling pathway GO:0030178 30 0.011
single organism localization GO:1902578 225 0.011
somatic stem cell maintenance GO:0035019 1 0.011
water homeostasis GO:0030104 4 0.011
cell cycle arrest GO:0007050 1 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
positive regulation of cellular protein metabolic process GO:0032270 22 0.011
regulation of reproductive process GO:2000241 4 0.011
negative regulation of histone modification GO:0031057 1 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.011
regulation of canonical wnt signaling pathway GO:0060828 34 0.011
response to external biotic stimulus GO:0043207 97 0.011
negative regulation of cell communication GO:0010648 96 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
hepaticobiliary system development GO:0061008 98 0.011
system process GO:0003008 185 0.011
Mouse
positive regulation of cell activation GO:0050867 1 0.010
protein localization to nucleus GO:0034504 3 0.010
muscle organ development GO:0007517 101 0.010
mesodermal cell fate commitment GO:0001710 14 0.010
protein modification process GO:0036211 100 0.010
neuron differentiation GO:0030182 353 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
metencephalon development GO:0022037 27 0.010
death GO:0016265 121 0.010
Human
positive regulation of immune effector process GO:0002699 3 0.010
fourth ventricle development GO:0021592 8 0.010
positive regulation of rna biosynthetic process GO:1902680 57 0.010
Human Mouse
sensory perception of pain GO:0019233 1 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010

hoxa5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
musculoskeletal system disease DOID:17 0 0.022
connective tissue disease DOID:65 0 0.022
disease of cellular proliferation DOID:14566 0 0.018
bone development disease DOID:0080006 0 0.013
bone disease DOID:0080001 0 0.013
nervous system disease DOID:863 0 0.010
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010