Danio rerio

0 known processes

sim1b

single-minded homolog 1b (Drosophila)

(Aliases: si:ch211-152c2.1)

sim1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
biosynthetic process GO:0009058 294 0.147
Zebrafish Mouse Fly
central nervous system development GO:0007417 387 0.131
Zebrafish Fly
generation of neurons GO:0048699 385 0.130
Zebrafish Fly
heterocycle metabolic process GO:0046483 290 0.092
Zebrafish Mouse Fly
catechol containing compound metabolic process GO:0009712 2 0.088
cellular biosynthetic process GO:0044249 286 0.080
Zebrafish Mouse Fly
regulation of transcription dna templated GO:0006355 213 0.079
Zebrafish Mouse Fly
organic cyclic compound metabolic process GO:1901360 301 0.079
Zebrafish Mouse Fly
larval development GO:0002164 2 0.077
aromatic compound biosynthetic process GO:0019438 217 0.077
Zebrafish Mouse Fly
adult behavior GO:0030534 2 0.074
Fly
heterocycle biosynthetic process GO:0018130 215 0.072
Zebrafish Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.072
Zebrafish Mouse Fly
cellular aromatic compound metabolic process GO:0006725 295 0.070
Zebrafish Mouse Fly
regulation of metabolic process GO:0019222 359 0.069
Zebrafish Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.067
Zebrafish Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.066
Zebrafish Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.063
Zebrafish Mouse Fly
compound eye development GO:0048749 2 0.061
gene expression GO:0010467 252 0.061
Zebrafish Mouse Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.059
Zebrafish Mouse Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.055
Zebrafish Mouse Fly
amine metabolic process GO:0009308 2 0.055
cellular amine metabolic process GO:0044106 2 0.055
cellular macromolecule metabolic process GO:0044260 391 0.052
Zebrafish Mouse Fly
head development GO:0060322 303 0.052
Zebrafish Fly
nitrogen compound metabolic process GO:0006807 319 0.051
Zebrafish Mouse Fly
cellular component morphogenesis GO:0032989 336 0.051
Zebrafish Fly
regulation of macromolecule metabolic process GO:0060255 317 0.047
Zebrafish Mouse Fly
catecholamine metabolic process GO:0006584 2 0.047
regulation of cellular amine metabolic process GO:0033238 0 0.047
phenol containing compound biosynthetic process GO:0046189 4 0.046
brain development GO:0007420 293 0.046
Zebrafish Fly
maintenance of location GO:0051235 4 0.046
nucleic acid metabolic process GO:0090304 244 0.045
Zebrafish Mouse Fly
phagocytosis GO:0006909 3 0.044
rna metabolic process GO:0016070 219 0.043
Zebrafish Mouse Fly
signal transduction GO:0007165 455 0.043
response to chemical GO:0042221 320 0.043
Zebrafish Fly
cell migration GO:0016477 237 0.043
response to amine GO:0014075 1 0.042
stem cell maintenance GO:0019827 4 0.042
transcription from rna polymerase ii promoter GO:0006366 80 0.041
Fly
forebrain development GO:0030900 96 0.041
Zebrafish
dopamine metabolic process GO:0042417 2 0.041
cellular response to external stimulus GO:0071496 2 0.038
regulation of cellular metabolic process GO:0031323 320 0.038
Zebrafish Mouse Fly
locomotion GO:0040011 313 0.038
Zebrafish Fly
response to external stimulus GO:0009605 264 0.037
Zebrafish Fly
regulation of rna metabolic process GO:0051252 224 0.037
Zebrafish Mouse Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.037
nucleobase containing compound metabolic process GO:0006139 274 0.037
Zebrafish Mouse Fly
organonitrogen compound metabolic process GO:1901564 74 0.036
neuron differentiation GO:0030182 353 0.035
Zebrafish Fly
cell surface receptor signaling pathway GO:0007166 325 0.035
rna biosynthetic process GO:0032774 181 0.035
Zebrafish Mouse Fly
macromolecule biosynthetic process GO:0009059 227 0.035
Zebrafish Mouse Fly
aging GO:0007568 2 0.034
cell part morphogenesis GO:0032990 246 0.034
Zebrafish Fly
locomotory behavior GO:0007626 34 0.034
Fly
regulation of cellular biosynthetic process GO:0031326 245 0.034
Zebrafish Mouse Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.034
Zebrafish Fly
sensory organ development GO:0007423 393 0.033
cellular ketone metabolic process GO:0042180 11 0.033
system process GO:0003008 185 0.033
regulation of rna biosynthetic process GO:2001141 213 0.032
Zebrafish Mouse Fly
multicellular organism growth GO:0035264 4 0.031
regulation of biological quality GO:0065008 263 0.031
regulation of cellular amino acid metabolic process GO:0006521 0 0.031
regulation of biosynthetic process GO:0009889 250 0.031
Zebrafish Mouse Fly
negative regulation of biological process GO:0048519 304 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.029
Zebrafish Mouse Fly
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.029
Zebrafish Fly
single organism metabolic process GO:0044710 217 0.029
regulation of gene expression GO:0010468 265 0.029
Zebrafish Mouse Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.029
regulation of primary metabolic process GO:0080090 311 0.028
Zebrafish Mouse Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.028
development of primary female sexual characteristics GO:0046545 4 0.028
transcription dna templated GO:0006351 181 0.028
Zebrafish Mouse Fly
neuron development GO:0048666 262 0.027
Zebrafish Fly
regulation of circadian rhythm GO:0042752 4 0.027
mitochondrion organization GO:0007005 4 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
response to amphetamine GO:0001975 1 0.025
cognition GO:0050890 1 0.025
neuron projection morphogenesis GO:0048812 161 0.025
Zebrafish Fly
tube morphogenesis GO:0035239 349 0.025
small molecule metabolic process GO:0044281 77 0.025
neuron projection development GO:0031175 180 0.025
Zebrafish Fly
neural crest cell differentiation GO:0014033 72 0.025
cell motility GO:0048870 244 0.024
dopaminergic neuron differentiation GO:0071542 14 0.024
Zebrafish
sequestering of calcium ion GO:0051208 3 0.024
cell projection organization GO:0030030 284 0.024
Zebrafish Fly
positive regulation of cellular process GO:0048522 201 0.024
Fly
nucleic acid templated transcription GO:0097659 181 0.024
Zebrafish Mouse Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.023
diencephalon development GO:0021536 58 0.023
Zebrafish
regulation of reproductive process GO:2000241 4 0.023
cellular amide metabolic process GO:0043603 4 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
Zebrafish Mouse Fly
sequestering of metal ion GO:0051238 3 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
Zebrafish Mouse Fly
negative regulation of signaling GO:0023057 96 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
organic acid metabolic process GO:0006082 31 0.023
sensory perception of chemical stimulus GO:0007606 3 0.022
positive regulation of transport GO:0051050 2 0.022
regulation of sequestering of calcium ion GO:0051282 4 0.022
cell morphogenesis GO:0000902 289 0.022
Zebrafish Fly
cellular response to extracellular stimulus GO:0031668 2 0.022
ear development GO:0043583 127 0.022
negative regulation of sequestering of calcium ion GO:0051283 4 0.021
regulation of synapse assembly GO:0051963 3 0.021
oxoacid metabolic process GO:0043436 31 0.021
g protein coupled receptor signaling pathway GO:0007186 74 0.021
cellular protein catabolic process GO:0044257 4 0.021
embryonic organ development GO:0048568 381 0.021
protein import GO:0017038 3 0.021
regulation of cell communication GO:0010646 232 0.021
olfactory lobe development GO:0021988 4 0.020
negative regulation of gliogenesis GO:0014014 1 0.020
multicellular organismal response to stress GO:0033555 2 0.020
negative regulation of cellular process GO:0048523 283 0.020
response to uv GO:0009411 3 0.020
female sex differentiation GO:0046660 4 0.020
lateral inhibition GO:0046331 1 0.020
cell differentiation in spinal cord GO:0021515 40 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
photoperiodism GO:0009648 11 0.020
regulation of signaling GO:0023051 235 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
regulation of blood pressure GO:0008217 1 0.019
olfactory bulb development GO:0021772 4 0.018
lipid storage GO:0019915 1 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
Fly
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.018
muscle structure development GO:0061061 196 0.018
regulation of response to stimulus GO:0048583 269 0.018
organic acid catabolic process GO:0016054 3 0.018
chemosensory behavior GO:0007635 1 0.018
kidney development GO:0001822 92 0.018
Mouse
negative regulation of catabolic process GO:0009895 3 0.018
hypothalamus development GO:0021854 14 0.018
Zebrafish
regulation of production of molecular mediator of immune response GO:0002700 1 0.018
cellular response to radiation GO:0071478 4 0.017
response to food GO:0032094 1 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
response to alkaloid GO:0043279 2 0.017
endocrine process GO:0050886 2 0.017
thermosensory behavior GO:0040040 1 0.017
regionalization GO:0003002 274 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
negative regulation of metabolic process GO:0009892 86 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
type b pancreatic cell development GO:0003323 4 0.016
mesenchyme development GO:0060485 127 0.016
positive regulation of rna biosynthetic process GO:1902680 57 0.016
Fly
single organism localization GO:1902578 225 0.016
regulation of developmental process GO:0050793 247 0.016
ribose phosphate biosynthetic process GO:0046390 20 0.016
regulation of dendrite development GO:0050773 3 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
organonitrogen compound biosynthetic process GO:1901566 47 0.016
eye development GO:0001654 277 0.016
heart development GO:0007507 313 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
Zebrafish Mouse Fly
cellular response to starvation GO:0009267 1 0.016
regulation of protein complex assembly GO:0043254 3 0.016
response to abiotic stimulus GO:0009628 122 0.016
Zebrafish
cell projection morphogenesis GO:0048858 244 0.016
Zebrafish Fly
meiotic nuclear division GO:0007126 4 0.016
gabaergic neuron differentiation GO:0097154 2 0.015
single organism organelle organization GO:1902589 199 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
protein metabolic process GO:0019538 183 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
taxis GO:0042330 109 0.015
Zebrafish Fly
axonogenesis GO:0007409 152 0.015
Zebrafish Fly
central nervous system neuron differentiation GO:0021953 74 0.015
female gonad development GO:0008585 4 0.015
ventral spinal cord development GO:0021517 35 0.015
lipid catabolic process GO:0016042 4 0.015
peptidyl serine modification GO:0018209 2 0.015
neural crest cell development GO:0014032 62 0.015
nuclear import GO:0051170 3 0.015
vasculature development GO:0001944 278 0.015
forebrain cell migration GO:0021885 1 0.014
positive regulation of biological process GO:0048518 253 0.014
Fly
protein import into nucleus GO:0006606 3 0.014
spinal cord development GO:0021510 46 0.014
microtubule organizing center organization GO:0031023 1 0.014
monoamine transport GO:0015844 1 0.014
regulation of endocrine process GO:0044060 2 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
centrosome organization GO:0051297 1 0.014
regulation of response to nutrient levels GO:0032107 1 0.014
camera type eye development GO:0043010 222 0.014
cellular component movement GO:0006928 335 0.014
Zebrafish Fly
behavior GO:0007610 74 0.014
Fly
cellular component biogenesis GO:0044085 178 0.014
hormone secretion GO:0046879 2 0.014
protein dephosphorylation GO:0006470 3 0.014
mesenchymal cell differentiation GO:0048762 87 0.014
regulation of cell activation GO:0050865 1 0.014
positive regulation of catabolic process GO:0009896 4 0.014
protein acetylation GO:0006473 2 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
energy reserve metabolic process GO:0006112 2 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
urogenital system development GO:0001655 97 0.014
Mouse
phagocytosis engulfment GO:0006911 1 0.014
multi organism process GO:0051704 134 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
positive regulation of gene expression GO:0010628 71 0.014
Fly
transport GO:0006810 220 0.013
protein targeting to nucleus GO:0044744 3 0.013
renal system development GO:0072001 94 0.013
Mouse
regulation of synaptic plasticity GO:0048167 1 0.013
autophagy GO:0006914 4 0.013
negative regulation of kinase activity GO:0033673 4 0.013
negative regulation of cell communication GO:0010648 96 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
Fly
morphogenesis of an epithelium GO:0002009 333 0.013
regulation of signal transduction GO:0009966 225 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
Zebrafish Mouse Fly
regulation of glial cell differentiation GO:0045685 4 0.013
regulation of transporter activity GO:0032409 2 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
cranial nerve development GO:0021545 42 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
nuclear transport GO:0051169 4 0.013
establishment of localization GO:0051234 244 0.013
programmed cell death GO:0012501 119 0.013
Zebrafish
response to stress GO:0006950 263 0.013
Zebrafish
regulation of neural precursor cell proliferation GO:2000177 3 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
localization of cell GO:0051674 244 0.013
regulation of hormone secretion GO:0046883 2 0.013
spinal cord motor neuron differentiation GO:0021522 26 0.012
hormone transport GO:0009914 2 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
locomotor rhythm GO:0045475 3 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
protein acylation GO:0043543 3 0.012
antimicrobial humoral response GO:0019730 2 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
regulation of response to extracellular stimulus GO:0032104 1 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
axon development GO:0061564 166 0.012
Zebrafish Fly
apoptotic process GO:0006915 116 0.012
Zebrafish
limbic system development GO:0021761 16 0.012
Zebrafish
regulation of binding GO:0051098 3 0.012
interspecies interaction between organisms GO:0044419 4 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
Fly
negative regulation of reproductive process GO:2000242 3 0.012
immune system process GO:0002376 241 0.012
sympathetic nervous system development GO:0048485 3 0.012
water homeostasis GO:0030104 4 0.012
cellular response to light stimulus GO:0071482 4 0.012
sprouting angiogenesis GO:0002040 53 0.012
response to external biotic stimulus GO:0043207 97 0.012
rhodopsin mediated signaling pathway GO:0016056 1 0.012
positive regulation of reproductive process GO:2000243 2 0.012
peptide transport GO:0015833 1 0.012
single organism nuclear import GO:1902593 3 0.012
response to endogenous stimulus GO:0009719 83 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
membrane fusion GO:0061025 2 0.011
digestive system development GO:0055123 289 0.011
stem cell development GO:0048864 82 0.011
protein stabilization GO:0050821 2 0.011
stem cell differentiation GO:0048863 117 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
synaptic target recognition GO:0008039 1 0.011
digestive tract development GO:0048565 265 0.011
optokinetic behavior GO:0007634 9 0.011
regulation of inflammatory response GO:0050727 2 0.011
entrainment of circadian clock GO:0009649 2 0.011
regulation of synapse organization GO:0050807 3 0.011
neuroblast proliferation GO:0007405 2 0.011
regulation of fatty acid metabolic process GO:0019217 1 0.011
regulation of metal ion transport GO:0010959 4 0.011
somatic stem cell maintenance GO:0035019 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
response to other organism GO:0051707 97 0.011
regulation of blood vessel size GO:0050880 2 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
protein localization to nucleus GO:0034504 3 0.011
positive regulation of histone modification GO:0031058 1 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
endocrine system development GO:0035270 65 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
cellular component disassembly GO:0022411 1 0.011
somatic muscle development GO:0007525 4 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
optomotor response GO:0071632 1 0.011
dicarboxylic acid transport GO:0006835 1 0.011
sleep GO:0030431 1 0.011
post embryonic organ development GO:0048569 4 0.011
membrane invagination GO:0010324 1 0.011
regulation of protein catabolic process GO:0042176 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
neuronal stem cell maintenance GO:0097150 2 0.011
sensory perception of pain GO:0019233 1 0.011
axon extension GO:0048675 45 0.010
hemopoiesis GO:0030097 183 0.010
negative chemotaxis GO:0050919 1 0.010
growth GO:0040007 174 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
regulation of response to biotic stimulus GO:0002831 2 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
multi organism cellular process GO:0044764 2 0.010
glial cell fate specification GO:0021780 4 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
positive regulation of chromatin modification GO:1903310 1 0.010
cellular response to nutrient levels GO:0031669 2 0.010
tissue remodeling GO:0048771 4 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
response to light stimulus GO:0009416 46 0.010
neurological system process GO:0050877 62 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
organelle organization GO:0006996 227 0.010
regulation of programmed cell death GO:0043067 101 0.010
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
Fly
positive regulation of cell cycle GO:0045787 3 0.010

sim1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
disease of metabolism DOID:0014667 0 0.015
Human
musculoskeletal system disease DOID:17 0 0.011