Danio rerio

52 known processes

sim1a

single-minded homolog 1a (Drosophila)

(Aliases: sim1)

sim1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
diencephalon development GO:0021536 58 0.976
cell morphogenesis GO:0000902 289 0.931
tube morphogenesis GO:0035239 349 0.858
cell projection morphogenesis GO:0048858 244 0.827
localization of cell GO:0051674 244 0.816
forebrain development GO:0030900 96 0.803
gabaergic neuron differentiation GO:0097154 2 0.791
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.790
nephron morphogenesis GO:0072028 2 0.748
cell projection organization GO:0030030 284 0.744
cellular component movement GO:0006928 335 0.729
nucleic acid templated transcription GO:0097659 181 0.721
Zebrafish Mouse Fly
forebrain generation of neurons GO:0021872 14 0.715
cellular component morphogenesis GO:0032989 336 0.703
cell morphogenesis involved in differentiation GO:0000904 195 0.695
locomotion GO:0040011 313 0.692
embryonic organ development GO:0048568 381 0.685
regulation of gene expression GO:0010468 265 0.678
Zebrafish Mouse Fly
development of primary female sexual characteristics GO:0046545 4 0.672
kidney development GO:0001822 92 0.636
Mouse
neuron projection development GO:0031175 180 0.610
cell motility GO:0048870 244 0.602
renal tubule morphogenesis GO:0061333 1 0.583
regulation of axon guidance GO:1902667 8 0.582
central nervous system development GO:0007417 387 0.581
head development GO:0060322 303 0.580
type b pancreatic cell development GO:0003323 4 0.568
axon development GO:0061564 166 0.564
nucleic acid metabolic process GO:0090304 244 0.561
Zebrafish Mouse Fly
axonogenesis GO:0007409 152 0.555
response to external stimulus GO:0009605 264 0.554
pronephric nephron development GO:0039019 14 0.543
neuron development GO:0048666 262 0.532
regulation of multicellular organismal process GO:0051239 277 0.529
forebrain neuron development GO:0021884 7 0.527
regulation of nitrogen compound metabolic process GO:0051171 251 0.518
Zebrafish Mouse Fly
central nervous system neuron differentiation GO:0021953 74 0.515
regulation of cell development GO:0060284 100 0.515
transcription from rna polymerase ii promoter GO:0006366 80 0.512
Fly
generation of neurons GO:0048699 385 0.501
forebrain cell migration GO:0021885 1 0.494
glomerular basement membrane development GO:0032836 5 0.478
brain development GO:0007420 293 0.459
nitrogen compound metabolic process GO:0006807 319 0.458
Zebrafish Mouse Fly
angiogenesis GO:0001525 158 0.454
nephron tubule morphogenesis GO:0072078 1 0.452
regulation of primary metabolic process GO:0080090 311 0.450
Zebrafish Mouse Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.449
embryonic camera type eye formation GO:0060900 10 0.446
cell growth GO:0016049 57 0.444
pronephros development GO:0048793 69 0.443
female sex differentiation GO:0046660 4 0.442
regulation of axon extension GO:0030516 24 0.415
regulation of nucleic acid templated transcription GO:1903506 213 0.412
Zebrafish Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.400
Zebrafish Mouse Fly
neuron projection morphogenesis GO:0048812 161 0.400
developmental cell growth GO:0048588 52 0.395
neuroblast differentiation GO:0014016 1 0.394
rna biosynthetic process GO:0032774 181 0.388
Zebrafish Mouse Fly
monoamine transport GO:0015844 1 0.381
regulation of multicellular organismal development GO:2000026 223 0.378
gene expression GO:0010467 252 0.374
Zebrafish Mouse Fly
developmental growth involved in morphogenesis GO:0060560 86 0.370
regulation of macromolecule metabolic process GO:0060255 317 0.368
Zebrafish Mouse Fly
cell migration GO:0016477 237 0.364
nephron epithelium morphogenesis GO:0072088 1 0.339
chordate embryonic development GO:0043009 271 0.337
signal transduction GO:0007165 455 0.332
thalamus development GO:0021794 6 0.311
response to chemical GO:0042221 320 0.309
regulation of organ morphogenesis GO:2000027 35 0.309
chemotaxis GO:0006935 104 0.306
pronephric glomerulus development GO:0039021 13 0.305
macromolecule biosynthetic process GO:0009059 227 0.304
Zebrafish Mouse Fly
forebrain neuron differentiation GO:0021879 14 0.297
embryonic organ morphogenesis GO:0048562 274 0.295
regulation of neuron migration GO:2001222 2 0.292
nucleobase containing compound biosynthetic process GO:0034654 205 0.290
Zebrafish Mouse Fly
positive regulation of reproductive process GO:2000243 2 0.261
heterocycle biosynthetic process GO:0018130 215 0.261
Zebrafish Mouse Fly
axon guidance GO:0007411 86 0.255
regulation of cellular biosynthetic process GO:0031326 245 0.255
Zebrafish Mouse Fly
morphogenesis of an epithelium GO:0002009 333 0.252
axon extension GO:0048675 45 0.252
cellular aromatic compound metabolic process GO:0006725 295 0.248
Zebrafish Mouse Fly
positive regulation of neuron migration GO:2001224 2 0.248
cell part morphogenesis GO:0032990 246 0.247
inner ear development GO:0048839 126 0.241
central nervous system neuron development GO:0021954 29 0.241
female gonad development GO:0008585 4 0.240
regulation of biological quality GO:0065008 263 0.240
glial cell migration GO:0008347 3 0.240
regulation of axonogenesis GO:0050770 32 0.239
morphogenesis of embryonic epithelium GO:0016331 30 0.239
regulation of cellular metabolic process GO:0031323 320 0.238
Zebrafish Mouse Fly
regulation of locomotion GO:0040012 55 0.235
neuron projection extension GO:1990138 45 0.232
developmental growth GO:0048589 166 0.232
synaptic target recognition GO:0008039 1 0.223
urogenital system development GO:0001655 97 0.223
Mouse
regulation of transcription dna templated GO:0006355 213 0.220
Zebrafish Mouse Fly
transcription dna templated GO:0006351 181 0.219
Zebrafish Mouse Fly
aromatic compound biosynthetic process GO:0019438 217 0.219
Zebrafish Mouse Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.218
cellular component assembly GO:0022607 170 0.215
skeletal system morphogenesis GO:0048705 102 0.214
embryonic digestive tract morphogenesis GO:0048557 3 0.213
negative regulation of biological process GO:0048519 304 0.210
response to nicotine GO:0035094 2 0.208
hypothalamus development GO:0021854 14 0.204
rna metabolic process GO:0016070 219 0.197
Zebrafish Mouse Fly
limbic system development GO:0021761 16 0.194
pancreatic a cell development GO:0003322 2 0.192
cellular biosynthetic process GO:0044249 286 0.188
Zebrafish Mouse Fly
cardiac cell fate commitment GO:0060911 1 0.183
nephron development GO:0072006 31 0.177
regulation of localization GO:0032879 104 0.176
release of sequestered calcium ion into cytosol GO:0051209 3 0.173
regulation of reproductive process GO:2000241 4 0.171
central nervous system neuron axonogenesis GO:0021955 18 0.167
epithelial cell morphogenesis GO:0003382 2 0.166
renal system development GO:0072001 94 0.163
Mouse
branching morphogenesis of a nerve GO:0048755 4 0.162
biosynthetic process GO:0009058 294 0.159
Zebrafish Mouse Fly
cell fate specification GO:0001708 68 0.155
nucleobase containing compound metabolic process GO:0006139 274 0.154
Zebrafish Mouse Fly
neural crest cell differentiation GO:0014033 72 0.154
cell surface receptor signaling pathway GO:0007166 325 0.152
cellular nitrogen compound biosynthetic process GO:0044271 218 0.152
Zebrafish Mouse Fly
cognition GO:0050890 1 0.151
cell fate commitment GO:0045165 99 0.148
Fly
regulation of response to stimulus GO:0048583 269 0.148
stem cell differentiation GO:0048863 117 0.148
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.147
Fly
regulation of cell morphogenesis GO:0022604 42 0.146
closure of optic fissure GO:0061386 6 0.146
blood vessel morphogenesis GO:0048514 216 0.142
organic cyclic compound biosynthetic process GO:1901362 223 0.139
Zebrafish Mouse Fly
regulation of cellular component movement GO:0051270 55 0.137
regulation of rna biosynthetic process GO:2001141 213 0.134
Zebrafish Mouse Fly
mesenchymal cell development GO:0014031 78 0.134
growth GO:0040007 174 0.134
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.129
Zebrafish Mouse Fly
regulation of biosynthetic process GO:0009889 250 0.129
Zebrafish Mouse Fly
positive regulation of embryonic development GO:0040019 3 0.128
organic substance biosynthetic process GO:1901576 289 0.128
Zebrafish Mouse Fly
olfactory bulb development GO:0021772 4 0.127
olfactory lobe development GO:0021988 4 0.126
regulation of glial cell differentiation GO:0045685 4 0.125
blood vessel development GO:0001568 246 0.124
heart development GO:0007507 313 0.121
retinal ganglion cell axon guidance GO:0031290 35 0.121
system process GO:0003008 185 0.117
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.116
cellular macromolecule metabolic process GO:0044260 391 0.114
Zebrafish Mouse Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.114
Zebrafish Mouse Fly
neural crest cell development GO:0014032 62 0.113
morphogenesis of an epithelial sheet GO:0002011 49 0.113
taxis GO:0042330 109 0.111
embryonic digestive tract development GO:0048566 4 0.111
sensory system development GO:0048880 76 0.109
embryonic camera type eye morphogenesis GO:0048596 19 0.109
cellular response to external stimulus GO:0071496 2 0.108
cell differentiation in spinal cord GO:0021515 40 0.108
otic vesicle development GO:0071599 42 0.106
regulation of organ growth GO:0046620 3 0.105
negative regulation of cell communication GO:0010648 96 0.105
nephron tubule epithelial cell differentiation GO:0072160 1 0.105
positive regulation of gene expression GO:0010628 71 0.104
Fly
regulation of metabolic process GO:0019222 359 0.104
Zebrafish Mouse Fly
establishment of localization GO:0051234 244 0.103
organic cyclic compound metabolic process GO:1901360 301 0.103
Zebrafish Mouse Fly
hepatocyte proliferation GO:0072574 2 0.103
regulation of apoptotic process GO:0042981 98 0.103
Zebrafish
regulation of developmental process GO:0050793 247 0.101
heterocycle metabolic process GO:0046483 290 0.098
Zebrafish Mouse Fly
cell proliferation GO:0008283 80 0.098
neurological system process GO:0050877 62 0.097
negative regulation of signaling GO:0023057 96 0.095
death GO:0016265 121 0.095
Zebrafish
cellular component biogenesis GO:0044085 178 0.094
aging GO:0007568 2 0.094
glomerular epithelial cell fate commitment GO:0072314 4 0.093
axon extension involved in axon guidance GO:0048846 10 0.093
neuron differentiation GO:0030182 353 0.092
response to growth factor GO:0070848 39 0.092
pronephric nephron tubule development GO:0039020 2 0.091
embryo development ending in birth or egg hatching GO:0009792 271 0.090
cell differentiation involved in kidney development GO:0061005 13 0.090
response to organic substance GO:0010033 153 0.089
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.089
response to endogenous stimulus GO:0009719 83 0.089
cardiocyte differentiation GO:0035051 44 0.088
olfactory bulb axon guidance GO:0071678 3 0.087
telencephalon development GO:0021537 14 0.087
regulation of blood pressure GO:0008217 1 0.086
otolith morphogenesis GO:0032474 8 0.086
endocrine system development GO:0035270 65 0.085
peripheral nervous system neuron axonogenesis GO:0048936 13 0.085
central nervous system projection neuron axonogenesis GO:0021952 15 0.084
regulation of anterior head development GO:2000742 2 0.084
ameboidal type cell migration GO:0001667 143 0.083
gastrulation GO:0007369 208 0.083
negative regulation of response to stimulus GO:0048585 104 0.082
midbrain hindbrain boundary development GO:0030917 23 0.081
embryonic skeletal system morphogenesis GO:0048704 93 0.078
negative regulation of stem cell differentiation GO:2000737 2 0.077
regulation of neuron differentiation GO:0045664 56 0.075
regulation of mechanoreceptor differentiation GO:0045631 1 0.075
pronephric glomerulus morphogenesis GO:0035775 6 0.075
forebrain regionalization GO:0021871 4 0.074
epithelial tube morphogenesis GO:0060562 148 0.074
regulation of cell motility GO:2000145 46 0.074
stem cell maintenance GO:0019827 4 0.073
wound healing GO:0042060 90 0.073
ear development GO:0043583 127 0.071
pancreatic d cell differentiation GO:0003311 2 0.070
negative regulation of gliogenesis GO:0014014 1 0.069
regulation of mrna splicing via spliceosome GO:0048024 3 0.069
regulation of extent of cell growth GO:0061387 29 0.068
regulation of axon extension involved in axon guidance GO:0048841 6 0.068
regulation of system process GO:0044057 40 0.067
positive regulation of biological process GO:0048518 253 0.066
Fly
regionalization GO:0003002 274 0.066
ventral spinal cord development GO:0021517 35 0.066
anterior head development GO:0097065 2 0.066
regulation of cell differentiation GO:0045595 142 0.066
semicircular canal development GO:0060872 24 0.065
catecholamine metabolic process GO:0006584 2 0.065
positive regulation of biosynthetic process GO:0009891 68 0.065
Fly
muscle structure development GO:0061061 196 0.065
ion transport GO:0006811 114 0.064
vasculature development GO:0001944 278 0.064
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.063
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.063
negative regulation of cell differentiation GO:0045596 46 0.062
embryonic skeletal joint development GO:0072498 3 0.061
ion transmembrane transport GO:0034220 91 0.061
phenol containing compound biosynthetic process GO:0046189 4 0.061
inner ear morphogenesis GO:0042472 63 0.061
kidney vasculature development GO:0061440 2 0.060
epithalamus development GO:0021538 10 0.060
kidney morphogenesis GO:0060993 15 0.060
positive regulation of developmental process GO:0051094 50 0.059
habenula development GO:0021986 9 0.059
fourth ventricle development GO:0021592 8 0.059
positive regulation of transport GO:0051050 2 0.059
cranial nerve development GO:0021545 42 0.058
positive regulation of cellular process GO:0048522 201 0.058
Fly
glomerulus development GO:0032835 27 0.058
regulation of neuron projection development GO:0010975 40 0.058
nephron epithelium development GO:0072009 16 0.058
regulation of rna metabolic process GO:0051252 224 0.058
Zebrafish Mouse Fly
response to abiotic stimulus GO:0009628 122 0.057
Zebrafish
circadian sleep wake cycle process GO:0022410 2 0.057
hypothalamus cell differentiation GO:0021979 4 0.055
negative regulation of apoptotic process GO:0043066 55 0.055
embryonic skeletal system development GO:0048706 97 0.055
morphogenesis of a branching structure GO:0001763 21 0.054
behavior GO:0007610 74 0.054
Fly
larval development GO:0002164 2 0.054
mesenchymal cell differentiation GO:0048762 87 0.054
sensory organ morphogenesis GO:0090596 200 0.053
cartilage development GO:0051216 96 0.053
negative regulation of cell death GO:0060548 60 0.052
transport GO:0006810 220 0.052
segmentation GO:0035282 97 0.052
regulation of cell migration GO:0030334 40 0.052
vesicle mediated transport GO:0016192 22 0.052
auditory receptor cell differentiation GO:0042491 15 0.052
negative regulation of cellular process GO:0048523 283 0.052
gliogenesis GO:0042063 45 0.051
cell death GO:0008219 121 0.051
Zebrafish
maintenance of location GO:0051235 4 0.050
epithelial cell fate commitment GO:0072148 11 0.050
immune system process GO:0002376 241 0.049
response to amphetamine GO:0001975 1 0.048
regulation of inner ear receptor cell differentiation GO:2000980 1 0.048
neuron migration GO:0001764 22 0.048
ear morphogenesis GO:0042471 64 0.047
ventral midline development GO:0007418 13 0.047
Fly
renal system vasculature development GO:0061437 2 0.047
cellular nitrogen compound metabolic process GO:0034641 290 0.047
Zebrafish Mouse Fly
nerve development GO:0021675 45 0.047
regulation of metal ion transport GO:0010959 4 0.046
positive regulation of multicellular organismal process GO:0051240 52 0.046
hormone secretion GO:0046879 2 0.046
cardiac muscle cell differentiation GO:0055007 30 0.046
positive regulation of rna biosynthetic process GO:1902680 57 0.045
Fly
programmed cell death GO:0012501 119 0.045
Zebrafish
cell migration involved in vasculogenesis GO:0035441 1 0.045
negative regulation of axon guidance GO:1902668 1 0.045
peripheral nervous system neuron differentiation GO:0048934 28 0.045
renal tubule development GO:0061326 5 0.044
gland development GO:0048732 143 0.044
regulation of embryonic development GO:0045995 47 0.044
single organism transport GO:0044765 206 0.044
regulation of ion transmembrane transporter activity GO:0032412 2 0.044
regulation of cellular component organization GO:0051128 86 0.044
catechol containing compound biosynthetic process GO:0009713 2 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.043
Fly
distal tubule development GO:0072017 1 0.043
negative regulation of multicellular organismal process GO:0051241 69 0.042
response to amine GO:0014075 1 0.042
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.042
axial mesoderm formation GO:0048320 4 0.042
negative regulation of signal transduction GO:0009968 94 0.042
regulation of mesoderm development GO:2000380 11 0.042
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.042
skeletal system development GO:0001501 181 0.042
cellular amine metabolic process GO:0044106 2 0.041
optic placode formation involved in camera type eye formation GO:0046619 3 0.041
kidney epithelium development GO:0072073 23 0.041
Mouse
enteric nervous system development GO:0048484 12 0.041
cation transport GO:0006812 81 0.041
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.041
regulation of systemic arterial blood pressure GO:0003073 1 0.040
response to oxygen containing compound GO:1901700 55 0.040
Zebrafish
neuron projection guidance GO:0097485 86 0.040
small molecule metabolic process GO:0044281 77 0.040
embryonic skeletal joint morphogenesis GO:0060272 3 0.040
positive regulation of nucleic acid templated transcription GO:1903508 57 0.040
Fly
pericardium development GO:0060039 1 0.039
regulation of cell size GO:0008361 29 0.039
single organism localization GO:1902578 225 0.039
mesenchyme development GO:0060485 127 0.039
astrocyte differentiation GO:0048708 1 0.039
glomerulus morphogenesis GO:0072102 7 0.038
carboxylic acid metabolic process GO:0019752 22 0.038
rhombomere development GO:0021546 19 0.038
negative regulation of mitosis GO:0045839 3 0.038
dopamine biosynthetic process GO:0042416 2 0.038
neural tube development GO:0021915 62 0.038
catechol containing compound metabolic process GO:0009712 2 0.038
connective tissue development GO:0061448 99 0.037
hair cell differentiation GO:0035315 32 0.037
dendrite guidance GO:0070983 0 0.037
sprouting angiogenesis GO:0002040 53 0.037
amine metabolic process GO:0009308 2 0.037
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.037
regulation of neurogenesis GO:0050767 87 0.037
branching morphogenesis of an epithelial tube GO:0048754 15 0.036
stem cell development GO:0048864 82 0.036
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.036
digestive system development GO:0055123 289 0.036
regulation of cellular amine metabolic process GO:0033238 0 0.035
cellular amino acid metabolic process GO:0006520 7 0.035
cardiac muscle tissue development GO:0048738 48 0.035
regulation of cell growth GO:0001558 29 0.035
embryonic neurocranium morphogenesis GO:0048702 15 0.035
dorsal ventral pattern formation GO:0009953 125 0.035
mesoderm formation GO:0001707 43 0.035
glomerulus vasculature development GO:0072012 2 0.035
cellular response to stress GO:0033554 62 0.035
epithelial cell differentiation GO:0030855 116 0.035
organ formation GO:0048645 17 0.035
adult behavior GO:0030534 2 0.035
Fly
regulation of mesodermal cell fate specification GO:0042661 9 0.035
anterior commissure morphogenesis GO:0021960 3 0.034
foregut morphogenesis GO:0007440 4 0.034
regulation of anatomical structure size GO:0090066 33 0.034
regulation of cell proliferation GO:0042127 37 0.033
gastrulation with mouth forming second GO:0001702 44 0.033
single organism behavior GO:0044708 24 0.033
Fly
response to organic cyclic compound GO:0014070 51 0.033
positive regulation of macromolecule metabolic process GO:0010604 93 0.032
Fly
positive regulation of gastrulation GO:2000543 2 0.032
morphogenesis of a branching epithelium GO:0061138 16 0.032
oxoacid metabolic process GO:0043436 31 0.032
regulation of chemotaxis GO:0050920 18 0.031
protein metabolic process GO:0019538 183 0.031
lateral inhibition GO:0046331 1 0.031
formation of primary germ layer GO:0001704 62 0.031
rhombomere boundary formation GO:0021654 10 0.031
regulation of gastrulation GO:0010470 24 0.030
oligodendrocyte cell fate specification GO:0021778 4 0.030
response to stress GO:0006950 263 0.030
Zebrafish
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.030
semicircular canal morphogenesis GO:0048752 18 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.030
Fly
regulation of cell projection organization GO:0031344 44 0.030
regulation of response to external stimulus GO:0032101 31 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.029
cellular response to estrogen stimulus GO:0071391 24 0.029
mesoderm morphogenesis GO:0048332 51 0.029
hemopoiesis GO:0030097 183 0.029
post embryonic organ development GO:0048569 4 0.029
catecholamine biosynthetic process GO:0042423 2 0.028
positive regulation of cellular metabolic process GO:0031325 94 0.028
Fly
inner ear receptor cell differentiation GO:0060113 29 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.028
circulatory system process GO:0003013 87 0.028
regulation of signaling GO:0023051 235 0.028
regulation of transmembrane transporter activity GO:0022898 2 0.027
auditory receptor cell fate commitment GO:0009912 4 0.027
regulation of circadian sleep wake cycle GO:0042749 1 0.027
mesodermal cell differentiation GO:0048333 21 0.027
positive regulation of neural precursor cell proliferation GO:2000179 1 0.027
epithelial cell differentiation involved in kidney development GO:0035850 13 0.027
motor neuron axon guidance GO:0008045 23 0.027
cellular amide metabolic process GO:0043603 4 0.027
visual behavior GO:0007632 10 0.027
axis specification GO:0009798 43 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.026
negative regulation of programmed cell death GO:0043069 58 0.026
positive regulation of cell development GO:0010720 25 0.026
otic placode formation GO:0043049 23 0.026
negative regulation of reproductive process GO:2000242 3 0.026
reproductive process GO:0022414 40 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.025
positive regulation of cellular component movement GO:0051272 11 0.025
regulation of stem cell differentiation GO:2000736 4 0.025
regulation of transporter activity GO:0032409 2 0.025
positive regulation of epithelial cell differentiation GO:0030858 2 0.024
regulation of endothelial cell differentiation GO:0045601 3 0.024
paraxial mesoderm morphogenesis GO:0048340 2 0.024
neuron apoptotic process GO:0051402 20 0.024
Zebrafish
spinal cord motor neuron differentiation GO:0021522 26 0.024
response to light stimulus GO:0009416 46 0.024
epidermal cell differentiation GO:0009913 36 0.024
regulation of oligodendrocyte differentiation GO:0048713 1 0.023
neuron fate commitment GO:0048663 26 0.023
receptor internalization GO:0031623 2 0.023
single organism metabolic process GO:0044710 217 0.023
trigeminal nerve development GO:0021559 3 0.023
neuron fate specification GO:0048665 20 0.023
cellular response to growth factor stimulus GO:0071363 39 0.023
axial mesodermal cell fate specification GO:0048327 3 0.023
notochord development GO:0030903 54 0.023
positive regulation of transcription dna templated GO:0045893 57 0.022
Fly
dopamine metabolic process GO:0042417 2 0.022
positive regulation of metabolic process GO:0009893 108 0.022
Fly
somite development GO:0061053 96 0.022
positive regulation of neurogenesis GO:0050769 24 0.022
compound eye development GO:0048749 2 0.022
embryonic cranial skeleton morphogenesis GO:0048701 90 0.022
auditory receptor cell development GO:0060117 8 0.022
negative regulation of developmental process GO:0051093 65 0.021
inner ear receptor cell fate commitment GO:0060120 4 0.021
regulation of nervous system development GO:0051960 90 0.021
muscle cell differentiation GO:0042692 139 0.021
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
negative regulation of blood circulation GO:1903523 2 0.021
spinal cord development GO:0021510 46 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
cellular response to oxygen levels GO:0071453 1 0.020
ventricular system development GO:0021591 12 0.020
cellular response to reactive oxygen species GO:0034614 2 0.020
cell cell signaling GO:0007267 52 0.020
organic acid metabolic process GO:0006082 31 0.020
floor plate morphogenesis GO:0033505 12 0.020
neural crest cell migration GO:0001755 42 0.020
tissue regeneration GO:0042246 74 0.020
regulation of cell fate specification GO:0042659 20 0.020
dendrite morphogenesis GO:0048813 5 0.020
signal transduction in absence of ligand GO:0038034 1 0.020
response to hexose GO:0009746 3 0.020
Zebrafish
apoptotic process involved in development GO:1902742 2 0.019
embryonic camera type eye development GO:0031076 29 0.019
floor plate development GO:0033504 15 0.019
rna stabilization GO:0043489 4 0.019
anterior posterior pattern specification GO:0009952 152 0.019
meiotic nuclear division GO:0007126 4 0.019
ectodermal placode morphogenesis GO:0071697 32 0.019
nephron tubule development GO:0072080 4 0.019
organelle organization GO:0006996 227 0.019
response to steroid hormone GO:0048545 35 0.019
blood circulation GO:0008015 87 0.019
cation transmembrane transport GO:0098655 65 0.019
regulation of circadian rhythm GO:0042752 4 0.019
regulation of cell communication GO:0010646 232 0.019
specification of symmetry GO:0009799 204 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.019
Zebrafish Mouse Fly
cellular protein metabolic process GO:0044267 129 0.019
response to monosaccharide GO:0034284 3 0.019
Zebrafish
positive regulation of response to stimulus GO:0048584 80 0.019
mesodermal cell migration GO:0008078 12 0.018
optomotor response GO:0071632 1 0.018
cell proliferation in hindbrain GO:0021534 4 0.018
peripheral nervous system neuron development GO:0048935 22 0.018
cellular response to nutrient levels GO:0031669 2 0.018
response to carbohydrate GO:0009743 3 0.018
Zebrafish
regulation of cell fate commitment GO:0010453 22 0.018
endodermal digestive tract morphogenesis GO:0061031 2 0.018
immune system development GO:0002520 191 0.018
epithelial cell development GO:0002064 42 0.018
multi organism process GO:0051704 134 0.018

sim1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.142
urinary system disease DOID:18 0 0.142
urinary system cancer DOID:3996 0 0.083
cancer DOID:162 0 0.083
disease of cellular proliferation DOID:14566 0 0.083
organ system cancer DOID:0050686 0 0.083
kidney disease DOID:557 0 0.018