Danio rerio

0 known processes

nme4

non-metastatic cells 4, protein expressed in

(Aliases: MGC56482,zgc:56482)

nme4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid storage GO:0019915 1 0.162
maintenance of location GO:0051235 4 0.149
cellular biosynthetic process GO:0044249 286 0.138
response to chemical GO:0042221 320 0.122
regulation of primary metabolic process GO:0080090 311 0.109
small molecule metabolic process GO:0044281 77 0.105
heart morphogenesis GO:0003007 156 0.100
neuron differentiation GO:0030182 353 0.099
cellular macromolecule metabolic process GO:0044260 391 0.097
nitrogen compound metabolic process GO:0006807 319 0.094
catechol containing compound metabolic process GO:0009712 2 0.092
organic substance biosynthetic process GO:1901576 289 0.090
generation of neurons GO:0048699 385 0.088
cellular aldehyde metabolic process GO:0006081 4 0.082
signal transduction GO:0007165 455 0.082
response to abiotic stimulus GO:0009628 122 0.080
regulation of biological quality GO:0065008 263 0.078
neuron development GO:0048666 262 0.076
central nervous system development GO:0007417 387 0.075
response to organic substance GO:0010033 153 0.070
gene expression GO:0010467 252 0.069
cell morphogenesis GO:0000902 289 0.066
organic cyclic compound metabolic process GO:1901360 301 0.065
aging GO:0007568 2 0.064
embryo development ending in birth or egg hatching GO:0009792 271 0.062
regulation of nitrogen compound metabolic process GO:0051171 251 0.062
cellular amine metabolic process GO:0044106 2 0.061
biosynthetic process GO:0009058 294 0.061
tube morphogenesis GO:0035239 349 0.059
regulation of gene expression GO:0010468 265 0.058
determination of left right symmetry GO:0007368 179 0.058
response to external stimulus GO:0009605 264 0.057
dopamine metabolic process GO:0042417 2 0.056
chordate embryonic development GO:0043009 271 0.055
regulation of signaling GO:0023051 235 0.055
positive regulation of transport GO:0051050 2 0.055
embryonic organ morphogenesis GO:0048562 274 0.053
larval development GO:0002164 2 0.052
response to vitamin GO:0033273 3 0.051
heterocycle biosynthetic process GO:0018130 215 0.050
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.050
stem cell proliferation GO:0072089 4 0.050
determination of bilateral symmetry GO:0009855 204 0.050
organonitrogen compound metabolic process GO:1901564 74 0.048
oxidation reduction process GO:0055114 41 0.047
response to stress GO:0006950 263 0.046
regulation of biosynthetic process GO:0009889 250 0.046
specification of symmetry GO:0009799 204 0.046
heterocycle metabolic process GO:0046483 290 0.046
single organism transport GO:0044765 206 0.045
single organism biosynthetic process GO:0044711 71 0.044
organic cyclic compound biosynthetic process GO:1901362 223 0.044
response to vitamin b3 GO:0033552 2 0.043
intracellular receptor signaling pathway GO:0030522 30 0.043
response to endogenous stimulus GO:0009719 83 0.043
amine metabolic process GO:0009308 2 0.043
diterpenoid metabolic process GO:0016101 15 0.043
cellular component morphogenesis GO:0032989 336 0.043
nucleobase containing compound metabolic process GO:0006139 274 0.042
taxis GO:0042330 109 0.042
digestive tract morphogenesis GO:0048546 231 0.042
macromolecule biosynthetic process GO:0009059 227 0.041
cellular nitrogen compound biosynthetic process GO:0044271 218 0.040
secondary metabolic process GO:0019748 3 0.040
phagocytosis GO:0006909 3 0.040
lipid catabolic process GO:0016042 4 0.039
nuclear transport GO:0051169 4 0.039
cellular nitrogen compound metabolic process GO:0034641 290 0.038
cell projection morphogenesis GO:0048858 244 0.038
lateral line development GO:0048882 66 0.037
regulation of neural precursor cell proliferation GO:2000177 3 0.036
embryonic organ development GO:0048568 381 0.036
neurotransmitter transport GO:0006836 2 0.036
digestive system development GO:0055123 289 0.036
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.035
homeostatic process GO:0042592 142 0.035
dopamine biosynthetic process GO:0042416 2 0.035
epithelial tube morphogenesis GO:0060562 148 0.035
regulation of metabolic process GO:0019222 359 0.035
regulation of cell communication GO:0010646 232 0.035
lipid metabolic process GO:0006629 52 0.035
regulation of rna biosynthetic process GO:2001141 213 0.034
adult behavior GO:0030534 2 0.034
neuroblast proliferation GO:0007405 2 0.034
response to hormone GO:0009725 48 0.034
catechol containing compound biosynthetic process GO:0009713 2 0.034
spermatid differentiation GO:0048515 2 0.033
protein targeting to nucleus GO:0044744 3 0.033
neuron projection morphogenesis GO:0048812 161 0.033
morphogenesis of an epithelium GO:0002009 333 0.033
cellular lipid metabolic process GO:0044255 36 0.033
embryonic heart tube morphogenesis GO:0003143 108 0.033
oocyte maturation GO:0001556 4 0.032
retinoic acid receptor signaling pathway GO:0048384 16 0.032
determination of heart left right asymmetry GO:0061371 117 0.032
regulation of cytokine production GO:0001817 3 0.031
single organism localization GO:1902578 225 0.031
lipid homeostasis GO:0055088 3 0.031
regulation of response to stimulus GO:0048583 269 0.031
heart development GO:0007507 313 0.031
response to alkaloid GO:0043279 2 0.030
single organism metabolic process GO:0044710 217 0.030
oxoacid metabolic process GO:0043436 31 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.029
response to steroid hormone GO:0048545 35 0.029
locomotion GO:0040011 313 0.029
organelle organization GO:0006996 227 0.029
cellular response to estrogen stimulus GO:0071391 24 0.029
neurotransmitter secretion GO:0007269 2 0.028
cellular response to chemical stimulus GO:0070887 157 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
heart looping GO:0001947 94 0.028
spermatid development GO:0007286 2 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
carboxylic acid metabolic process GO:0019752 22 0.028
rna biosynthetic process GO:0032774 181 0.027
cellular macromolecule biosynthetic process GO:0034645 224 0.027
immune system development GO:0002520 191 0.027
positive regulation of cellular catabolic process GO:0031331 3 0.027
organic acid metabolic process GO:0006082 31 0.027
brain development GO:0007420 293 0.027
regulation of synaptic plasticity GO:0048167 1 0.027
trabecula morphogenesis GO:0061383 2 0.027
axon guidance GO:0007411 86 0.027
nuclear import GO:0051170 3 0.027
regionalization GO:0003002 274 0.027
lateral line system development GO:0048925 76 0.027
response to uv GO:0009411 3 0.026
transport GO:0006810 220 0.026
retinoid metabolic process GO:0001523 15 0.026
cellular protein catabolic process GO:0044257 4 0.026
multicellular organism growth GO:0035264 4 0.025
meiotic nuclear division GO:0007126 4 0.025
positive regulation of cell activation GO:0050867 1 0.025
organonitrogen compound biosynthetic process GO:1901566 47 0.025
single organism organelle organization GO:1902589 199 0.025
response to nutrient GO:0007584 3 0.025
axon development GO:0061564 166 0.025
immune system process GO:0002376 241 0.025
regulation of cell activation GO:0050865 1 0.025
negative regulation of biological process GO:0048519 304 0.025
catecholamine biosynthetic process GO:0042423 2 0.025
cell part morphogenesis GO:0032990 246 0.025
small molecule catabolic process GO:0044282 3 0.025
response to glucose GO:0009749 3 0.024
melanin metabolic process GO:0006582 2 0.024
multi organism process GO:0051704 134 0.024
alcohol biosynthetic process GO:0046165 2 0.024
monoamine transport GO:0015844 1 0.024
regulation of signal transduction GO:0009966 225 0.024
phosphate containing compound metabolic process GO:0006796 108 0.024
regulation of macromolecule biosynthetic process GO:0010556 225 0.024
regulation of rna metabolic process GO:0051252 224 0.023
regulation of metal ion transport GO:0010959 4 0.023
transcription dna templated GO:0006351 181 0.023
cellular response to steroid hormone stimulus GO:0071383 31 0.023
g protein coupled receptor signaling pathway GO:0007186 74 0.023
chemosensory behavior GO:0007635 1 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
phosphorus metabolic process GO:0006793 109 0.023
positive regulation of secretion GO:0051047 1 0.023
protein modification process GO:0036211 100 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
hepaticobiliary system development GO:0061008 98 0.023
single organism nuclear import GO:1902593 3 0.023
heart contraction GO:0060047 71 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
axonogenesis GO:0007409 152 0.022
pancreas development GO:0031016 84 0.022
ion transport GO:0006811 114 0.022
regulation of stem cell proliferation GO:0072091 2 0.022
specification of organ identity GO:0010092 2 0.022
sensory system development GO:0048880 76 0.022
regulation of reproductive process GO:2000241 4 0.022
programmed cell death GO:0012501 119 0.022
gland development GO:0048732 143 0.022
negative regulation of cytokine production GO:0001818 1 0.022
somite development GO:0061053 96 0.021
response to fatty acid GO:0070542 5 0.021
nucleic acid metabolic process GO:0090304 244 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
cellular response to organic cyclic compound GO:0071407 38 0.021
leukocyte proliferation GO:0070661 1 0.021
nucleic acid templated transcription GO:0097659 181 0.021
chemotaxis GO:0006935 104 0.021
cellular response to organic substance GO:0071310 105 0.021
epithelial cell differentiation GO:0030855 116 0.021
cell motility GO:0048870 244 0.020
protein import into nucleus GO:0006606 3 0.020
response to glucocorticoid GO:0051384 1 0.020
regulation of transcription dna templated GO:0006355 213 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
retinal metabolic process GO:0042574 3 0.020
b cell activation GO:0042113 2 0.020
heart process GO:0003015 71 0.020
positive regulation of cellular biosynthetic process GO:0031328 68 0.020
regulation of mrna splicing via spliceosome GO:0048024 3 0.020
establishment of localization GO:0051234 244 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
phenol containing compound biosynthetic process GO:0046189 4 0.019
digestive tract development GO:0048565 265 0.019
cellular response to external stimulus GO:0071496 2 0.019
response to lipid GO:0033993 60 0.019
response to hexose GO:0009746 3 0.019
regulation of sodium ion transport GO:0002028 2 0.019
stem cell division GO:0017145 1 0.019
regulation of binding GO:0051098 3 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
energy reserve metabolic process GO:0006112 2 0.019
protein import GO:0017038 3 0.019
cation transport GO:0006812 81 0.019
mesenchyme development GO:0060485 127 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.018
response to wounding GO:0009611 116 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
hormone transport GO:0009914 2 0.018
cellular hormone metabolic process GO:0034754 19 0.018
positive regulation of translation GO:0045727 1 0.018
meiotic cell cycle process GO:1903046 3 0.018
positive regulation of catabolic process GO:0009896 4 0.018
female meiotic division GO:0007143 2 0.018
peripheral nervous system development GO:0007422 55 0.018
response to carbohydrate GO:0009743 3 0.018
response to corticosteroid GO:0031960 1 0.018
cellular component movement GO:0006928 335 0.018
hormone secretion GO:0046879 2 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
response to ketone GO:1901654 1 0.017
cell cell recognition GO:0009988 1 0.017
long chain fatty acid metabolic process GO:0001676 1 0.017
aromatic amino acid family metabolic process GO:0009072 1 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.017
head development GO:0060322 303 0.017
glucose homeostasis GO:0042593 1 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
stem cell maintenance GO:0019827 4 0.017
cellular response to lipid GO:0071396 39 0.017
intracellular signal transduction GO:0035556 85 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
cell projection organization GO:0030030 284 0.016
somitogenesis GO:0001756 87 0.016
organic hydroxy compound metabolic process GO:1901615 16 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
regulation of neurotransmitter secretion GO:0046928 1 0.016
response to drug GO:0042493 3 0.016
apical junction assembly GO:0043297 1 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
atp catabolic process GO:0006200 4 0.016
regulation of inflammatory response GO:0050727 2 0.016
cytoskeleton organization GO:0007010 96 0.016
actin cytoskeleton organization GO:0030036 63 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
positive regulation of epithelial cell proliferation GO:0050679 1 0.015
cellular response to endogenous stimulus GO:0071495 68 0.015
neuron projection guidance GO:0097485 86 0.015
response to monosaccharide GO:0034284 3 0.015
hindbrain development GO:0030902 91 0.015
establishment of endothelial barrier GO:0061028 3 0.015
positive regulation of cellular process GO:0048522 201 0.015
response to radiation GO:0009314 51 0.015
regulation of organ growth GO:0046620 3 0.015
cellular component biogenesis GO:0044085 178 0.015
regulation of programmed cell death GO:0043067 101 0.015
peptide metabolic process GO:0006518 1 0.015
protein localization to nucleus GO:0034504 3 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
estrogen metabolic process GO:0008210 2 0.014
b cell differentiation GO:0030183 1 0.014
response to organic cyclic compound GO:0014070 51 0.014
cell migration GO:0016477 237 0.014
apoptotic signaling pathway GO:0097190 23 0.014
neuron projection development GO:0031175 180 0.014
muscle cell differentiation GO:0042692 139 0.014
rna metabolic process GO:0016070 219 0.014
regulation of synapse organization GO:0050807 3 0.014
striated muscle cell differentiation GO:0051146 129 0.014
negative regulation of kinase activity GO:0033673 4 0.014
endocrine system development GO:0035270 65 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
mitochondrion organization GO:0007005 4 0.014
skeletal system development GO:0001501 181 0.014
segmentation GO:0035282 97 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
regulation of apoptotic process GO:0042981 98 0.014
hindbrain morphogenesis GO:0021575 22 0.013
system process GO:0003008 185 0.013
tissue remodeling GO:0048771 4 0.013
cell cell signaling GO:0007267 52 0.013
positive regulation of leukocyte differentiation GO:1902107 1 0.013
cellular biogenic amine metabolic process GO:0006576 2 0.013
positive regulation of stem cell proliferation GO:2000648 1 0.013
peptide transport GO:0015833 1 0.013
phosphorylation GO:0016310 69 0.013
dna templated transcription elongation GO:0006354 3 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
multicellular organismal response to stress GO:0033555 2 0.013
sensory organ development GO:0007423 393 0.013
death GO:0016265 121 0.013
renal tubule morphogenesis GO:0061333 1 0.013
protein secretion GO:0009306 1 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
urogenital system development GO:0001655 97 0.013
terpenoid metabolic process GO:0006721 15 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
posterior lateral line development GO:0048916 38 0.013
actin filament based process GO:0030029 64 0.013
pyruvate metabolic process GO:0006090 1 0.013
cell differentiation in spinal cord GO:0021515 40 0.013
negative regulation of cellular process GO:0048523 283 0.013
membrane invagination GO:0010324 1 0.013
organelle assembly GO:0070925 110 0.013
regulation of cell death GO:0010941 103 0.012
cellular response to hormone stimulus GO:0032870 39 0.012
regulation of neurogenesis GO:0050767 87 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
positive regulation of cytokine production GO:0001819 2 0.012
lymphocyte proliferation GO:0046651 1 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
mechanosensory lateral line system development GO:0048881 49 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
endocrine pancreas development GO:0031018 27 0.012
cellular lipid catabolic process GO:0044242 3 0.012
single fertilization GO:0007338 3 0.012
regulation of hormone secretion GO:0046883 2 0.012
protein metabolic process GO:0019538 183 0.012
regulation of protein catabolic process GO:0042176 1 0.012
response to estrogen GO:0043627 27 0.012
positive regulation of metabolic process GO:0009893 108 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
gtp catabolic process GO:0006184 2 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
organic substance transport GO:0071702 58 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
hormone biosynthetic process GO:0042446 3 0.011
response to hydrogen peroxide GO:0042542 3 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
eye photoreceptor cell differentiation GO:0001754 45 0.011
cell proliferation GO:0008283 80 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of molecular function GO:0065009 70 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
ameboidal type cell migration GO:0001667 143 0.011
response to oxygen containing compound GO:1901700 55 0.011
cellular response to stress GO:0033554 62 0.011
fat soluble vitamin metabolic process GO:0006775 4 0.011
calcium ion import GO:0070509 4 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
regulation of gtpase activity GO:0043087 2 0.011
positive regulation of immune effector process GO:0002699 3 0.011
camera type eye development GO:0043010 222 0.011
regulation of developmental process GO:0050793 247 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
nephron morphogenesis GO:0072028 2 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
cation homeostasis GO:0055080 33 0.011
gastrulation GO:0007369 208 0.011
anterior posterior pattern specification GO:0009952 152 0.011
apoptotic process GO:0006915 116 0.011
muscle cell development GO:0055001 115 0.011
behavior GO:0007610 74 0.011
response to xenobiotic stimulus GO:0009410 45 0.010
cellular ketone metabolic process GO:0042180 11 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
regulation of response to nutrient levels GO:0032107 1 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
embryonic heart tube development GO:0035050 133 0.010
positive regulation of gene expression GO:0010628 71 0.010
mononuclear cell proliferation GO:0032943 1 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
negative regulation of catabolic process GO:0009895 3 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
triglyceride homeostasis GO:0070328 2 0.010
response to topologically incorrect protein GO:0035966 2 0.010

nme4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.015
sensory system disease DOID:0050155 0 0.013
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011