Danio rerio

0 known processes

lhx1a

LIM homeobox 1a

(Aliases: LHX1,lim1,wu:fe25d04,wu:fj36b06)

lhx1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
head development GO:0060322 303 0.998
Zebrafish Mouse
central nervous system development GO:0007417 387 0.998
Zebrafish Mouse
neuron fate commitment GO:0048663 26 0.991
Zebrafish
cellular biosynthetic process GO:0044249 286 0.989
Mouse Fly
regulation of metabolic process GO:0019222 359 0.987
Zebrafish Mouse Fly
regulation of gene expression GO:0010468 265 0.984
Zebrafish Mouse Fly
regulation of cellular metabolic process GO:0031323 320 0.982
Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.981
Mouse Fly
digestive system development GO:0055123 289 0.978
Zebrafish Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.978
Mouse Fly
nucleic acid metabolic process GO:0090304 244 0.976
Mouse Fly
organic cyclic compound metabolic process GO:1901360 301 0.976
Mouse Fly
regulation of rna metabolic process GO:0051252 224 0.971
Mouse Fly
nucleic acid templated transcription GO:0097659 181 0.971
Mouse Fly
rna biosynthetic process GO:0032774 181 0.966
Mouse Fly
cell fate specification GO:0001708 68 0.964
Zebrafish Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.957
Mouse Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.955
Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.944
cell morphogenesis GO:0000902 289 0.943
Zebrafish Mouse
mesoderm development GO:0007498 88 0.939
nucleobase containing compound biosynthetic process GO:0034654 205 0.939
Mouse Fly
eye development GO:0001654 277 0.938
Zebrafish Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.938
Mouse Fly
axon development GO:0061564 166 0.937
Zebrafish Mouse Worm
specification of symmetry GO:0009799 204 0.936
gene expression GO:0010467 252 0.936
Zebrafish Mouse Fly
negative regulation of biological process GO:0048519 304 0.935
Mouse Fly
hair cell differentiation GO:0035315 32 0.932
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.931
Zebrafish Mouse
cellular component morphogenesis GO:0032989 336 0.926
Zebrafish Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.926
Zebrafish Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.925
Mouse Fly
axonogenesis GO:0007409 152 0.923
Zebrafish Mouse
signal transduction GO:0007165 455 0.922
positive regulation of rna metabolic process GO:0051254 59 0.921
Mouse Fly
cellular aromatic compound metabolic process GO:0006725 295 0.920
Mouse Fly
determination of bilateral symmetry GO:0009855 204 0.903
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.900
Zebrafish Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.894
Mouse Fly
generation of neurons GO:0048699 385 0.889
Zebrafish Mouse Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.888
Mouse Fly
locomotion GO:0040011 313 0.884
Zebrafish Mouse Worm
pancreas development GO:0031016 84 0.876
Zebrafish
epithelial cell differentiation GO:0030855 116 0.874
Zebrafish Mouse
regulation of response to stimulus GO:0048583 269 0.874
organic cyclic compound biosynthetic process GO:1901362 223 0.865
Mouse Fly
regulation of multicellular organismal development GO:2000026 223 0.863
Mouse Worm
glomerulus development GO:0032835 27 0.861
Zebrafish Rat
enteroendocrine cell differentiation GO:0035883 9 0.861
Zebrafish
rna metabolic process GO:0016070 219 0.859
Mouse Fly
neuron development GO:0048666 262 0.850
Zebrafish Mouse Worm
cell part morphogenesis GO:0032990 246 0.845
Zebrafish Mouse
mechanoreceptor differentiation GO:0042490 37 0.844
Zebrafish
taxis GO:0042330 109 0.842
Zebrafish Mouse
brain development GO:0007420 293 0.841
Zebrafish Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.836
Zebrafish Mouse
determination of left right symmetry GO:0007368 179 0.835
positive regulation of cellular process GO:0048522 201 0.834
Mouse Fly
rostrocaudal neural tube patterning GO:0021903 29 0.832
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.820
Zebrafish Mouse Worm
neuron fate determination GO:0048664 2 0.819
pronephros development GO:0048793 69 0.818
Zebrafish Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.815
Mouse Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.812
Zebrafish Mouse
negative regulation of cellular process GO:0048523 283 0.808
Mouse Fly
positive regulation of biological process GO:0048518 253 0.806
Mouse Worm Fly
neuron projection morphogenesis GO:0048812 161 0.804
Zebrafish Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.803
Mouse Fly
larval development GO:0002164 2 0.794
Worm
neural tube patterning GO:0021532 33 0.785
Zebrafish
diencephalon development GO:0021536 58 0.782
Zebrafish
cell projection organization GO:0030030 284 0.781
Zebrafish Mouse Worm
midbrain hindbrain boundary development GO:0030917 23 0.779
Zebrafish
stem cell differentiation GO:0048863 117 0.778
heart development GO:0007507 313 0.777
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.776
Mouse Fly
nephron epithelium development GO:0072009 16 0.764
Mouse
neuron differentiation GO:0030182 353 0.760
Zebrafish Mouse Worm
nephron development GO:0072006 31 0.759
Zebrafish Mouse Rat
negative regulation of rna metabolic process GO:0051253 48 0.759
Mouse Fly
pronephric glomerulus morphogenesis GO:0035775 6 0.754
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.753
Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.751
Mouse Fly
transcription dna templated GO:0006351 181 0.750
Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.745
Mouse Fly
regulation of developmental process GO:0050793 247 0.738
Mouse Worm
type b pancreatic cell development GO:0003323 4 0.726
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.723
Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.709
Mouse
ventral spinal cord development GO:0021517 35 0.709
Zebrafish Mouse
hindbrain development GO:0030902 91 0.704
Zebrafish Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.700
Mouse Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.700
Mouse Fly
regulation of transcription dna templated GO:0006355 213 0.693
Mouse Fly
pronephric glomerulus development GO:0039021 13 0.679
Zebrafish
gastrulation GO:0007369 208 0.676
Mouse
epithelial cell development GO:0002064 42 0.676
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.675
Mouse Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.674
nephron epithelium morphogenesis GO:0072088 1 0.664
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.662
Mouse Fly
aromatic compound biosynthetic process GO:0019438 217 0.662
Mouse Fly
forebrain generation of neurons GO:0021872 14 0.655
digestive tract morphogenesis GO:0048546 231 0.655
Mouse
regulation of cell development GO:0060284 100 0.652
negative regulation of gene expression GO:0010629 65 0.645
Mouse Fly
positive regulation of gene expression GO:0010628 71 0.643
Mouse Fly
neurological system process GO:0050877 62 0.639
central nervous system neuron differentiation GO:0021953 74 0.638
Zebrafish Mouse
embryonic organ development GO:0048568 381 0.632
Zebrafish Mouse
cell proliferation GO:0008283 80 0.629
positive regulation of epithelial cell differentiation GO:0030858 2 0.620
Mouse
cell fate commitment GO:0045165 99 0.617
Zebrafish Worm
regulation of neural precursor cell proliferation GO:2000177 3 0.617
Mouse
embryonic organ morphogenesis GO:0048562 274 0.601
Zebrafish Mouse
heterocycle biosynthetic process GO:0018130 215 0.600
Mouse Fly
axon guidance GO:0007411 86 0.597
Zebrafish Mouse
cardiocyte differentiation GO:0035051 44 0.596
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.589
regulation of signal transduction GO:0009966 225 0.583
chemotaxis GO:0006935 104 0.582
Zebrafish Mouse
camera type eye development GO:0043010 222 0.579
Zebrafish Mouse
muscle cell differentiation GO:0042692 139 0.578
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.577
Mouse Fly
heart morphogenesis GO:0003007 156 0.566
regulation of signaling GO:0023051 235 0.565
stem cell maintenance GO:0019827 4 0.562
photoreceptor cell fate specification GO:0043704 1 0.557
determination of heart left right asymmetry GO:0061371 117 0.544
nephron morphogenesis GO:0072028 2 0.543
Mouse Rat
eye morphogenesis GO:0048592 144 0.542
Zebrafish Mouse
auditory receptor cell fate commitment GO:0009912 4 0.533
regulation of glial cell differentiation GO:0045685 4 0.529
cell motility GO:0048870 244 0.527
Mouse Worm
forebrain neuron fate commitment GO:0021877 1 0.527
response to external stimulus GO:0009605 264 0.527
Zebrafish Mouse
striated muscle cell differentiation GO:0051146 129 0.524
Zebrafish
biosynthetic process GO:0009058 294 0.522
Mouse Fly
regulation of oligodendrocyte differentiation GO:0048713 1 0.521
atrioventricular valve formation GO:0003190 3 0.516
regulation of embryonic development GO:0045995 47 0.513
Mouse
response to chemical GO:0042221 320 0.508
Zebrafish Mouse Rat
semicircular canal development GO:0060872 24 0.502
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.498
Zebrafish Mouse
regulation of biosynthetic process GO:0009889 250 0.491
Mouse Fly
heart looping GO:0001947 94 0.490
nephron tubule morphogenesis GO:0072078 1 0.484
Mouse
nephric duct morphogenesis GO:0072178 7 0.482
Mouse
localization of cell GO:0051674 244 0.482
Mouse Worm
muscle structure development GO:0061061 196 0.477
Zebrafish
regulation of cell differentiation GO:0045595 142 0.474
Mouse Worm
ear morphogenesis GO:0042471 64 0.466
Zebrafish
motor neuron axon guidance GO:0008045 23 0.464
Mouse
glandular epithelial cell differentiation GO:0002067 9 0.463
Zebrafish
positive regulation of neural precursor cell proliferation GO:2000179 1 0.462
Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.462
forebrain regionalization GO:0021871 4 0.451
Mouse
neuroblast fate commitment GO:0014017 1 0.446
system process GO:0003008 185 0.445
Zebrafish
mechanosensory lateral line system development GO:0048881 49 0.444
heterocycle metabolic process GO:0046483 290 0.441
Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.438
Mouse Fly
regulation of endodermal cell fate specification GO:0042663 15 0.437
regulation of neurogenesis GO:0050767 87 0.436
muscle organ development GO:0007517 101 0.433
cell cell signaling GO:0007267 52 0.427
Mouse
neuron projection guidance GO:0097485 86 0.424
Zebrafish Mouse
endocrine pancreas development GO:0031018 27 0.423
Zebrafish
inner ear receptor cell differentiation GO:0060113 29 0.421
Zebrafish
negative regulation of gliogenesis GO:0014014 1 0.418
neuroblast fate determination GO:0007400 1 0.416
endocrine system development GO:0035270 65 0.398
Zebrafish
digestive tract development GO:0048565 265 0.394
Mouse
kidney development GO:0001822 92 0.394
Zebrafish Mouse Rat
negative regulation of cellular biosynthetic process GO:0031327 55 0.393
Mouse Fly
somite development GO:0061053 96 0.391
Mouse
response to stress GO:0006950 263 0.391
astrocyte differentiation GO:0048708 1 0.391
segmentation GO:0035282 97 0.389
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.387
Mouse Fly
spinal cord development GO:0021510 46 0.378
Zebrafish Mouse
neuron projection development GO:0031175 180 0.377
Zebrafish Mouse Worm
pericardium development GO:0060039 1 0.374
lateral inhibition GO:0046331 1 0.374
endodermal cell fate specification GO:0001714 17 0.373
positive regulation of epithelial cell proliferation GO:0050679 1 0.370
reproduction GO:0000003 40 0.368
Worm
positive regulation of nervous system development GO:0051962 25 0.365
Mouse
urogenital system development GO:0001655 97 0.364
Zebrafish Mouse Rat
programmed cell death GO:0012501 119 0.363
behavior GO:0007610 74 0.362
Zebrafish Worm
regionalization GO:0003002 274 0.360
Zebrafish Mouse Fly
multi organism process GO:0051704 134 0.358
Worm
forebrain development GO:0030900 96 0.358
Zebrafish Mouse
cell cycle GO:0007049 93 0.354
regulation of cell communication GO:0010646 232 0.353
axial mesoderm formation GO:0048320 4 0.349
negative regulation of biosynthetic process GO:0009890 55 0.349
Mouse Fly
apoptotic process GO:0006915 116 0.347
striated muscle tissue development GO:0014706 110 0.345
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.345
Mouse Fly
hindbrain morphogenesis GO:0021575 22 0.340
Mouse
stem cell fate commitment GO:0048865 1 0.336
metencephalon development GO:0022037 27 0.336
Mouse
ventral spinal cord interneuron fate commitment GO:0060579 3 0.336
pancreatic a cell development GO:0003322 2 0.333
Zebrafish
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.333
negative regulation of response to stimulus GO:0048585 104 0.329
cellular component movement GO:0006928 335 0.328
Zebrafish Mouse Worm
response to biotic stimulus GO:0009607 97 0.327
cell death GO:0008219 121 0.327
negative regulation of cellular metabolic process GO:0031324 77 0.321
Mouse Fly
muscle tissue development GO:0060537 110 0.321
Zebrafish
regulation of neuron differentiation GO:0045664 56 0.319
renal tubule morphogenesis GO:0061333 1 0.317
Mouse
inner ear receptor cell development GO:0060119 20 0.314
Zebrafish
pharyngeal muscle development GO:0043282 4 0.313
camera type eye morphogenesis GO:0048593 108 0.310
Zebrafish Mouse
renal system development GO:0072001 94 0.309
Zebrafish Mouse Rat
organelle organization GO:0006996 227 0.305
skin development GO:0043588 54 0.303
Zebrafish
negative regulation of macromolecule metabolic process GO:0010605 76 0.300
Mouse Fly
type b pancreatic cell differentiation GO:0003309 8 0.298
Zebrafish
somitogenesis GO:0001756 87 0.298
Mouse
cell proliferation in forebrain GO:0021846 3 0.295
negative regulation of metabolic process GO:0009892 86 0.292
Mouse Fly
appendage morphogenesis GO:0035107 56 0.292
Fly
photoreceptor cell fate commitment GO:0046552 1 0.287
regulation of cell proliferation GO:0042127 37 0.286
Mouse
gliogenesis GO:0042063 45 0.279
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.277
Mouse Fly
thalamus development GO:0021794 6 0.274
Zebrafish
pronephros morphogenesis GO:0072114 14 0.273
telencephalon development GO:0021537 14 0.272
Zebrafish Mouse
oligodendrocyte cell fate specification GO:0021778 4 0.267
exocrine pancreas development GO:0031017 28 0.267
Zebrafish
tube morphogenesis GO:0035239 349 0.264
Zebrafish Mouse
nephron tubule epithelial cell differentiation GO:0072160 1 0.263
Mouse
multicellular organismal reproductive process GO:0048609 35 0.262
Worm
inner ear development GO:0048839 126 0.260
Zebrafish
photoreceptor cell development GO:0042461 40 0.260
immune system process GO:0002376 241 0.259
embryonic heart tube development GO:0035050 133 0.254
cellular component assembly GO:0022607 170 0.249
cell differentiation involved in kidney development GO:0061005 13 0.249
Mouse
regulation of inner ear receptor cell differentiation GO:2000980 1 0.247
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.246
Mouse Fly
positive regulation of cellular metabolic process GO:0031325 94 0.242
Mouse Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.242
Mouse Fly
appendage development GO:0048736 80 0.239
Fly
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.237
gabaergic neuron differentiation GO:0097154 2 0.234
Zebrafish
spermatid differentiation GO:0048515 2 0.234
aging GO:0007568 2 0.230
neural precursor cell proliferation GO:0061351 20 0.230
sensory perception GO:0007600 39 0.230
stem cell development GO:0048864 82 0.224
multi organism reproductive process GO:0044703 36 0.224
Worm
cognition GO:0050890 1 0.223
organ formation GO:0048645 17 0.223
developmental process involved in reproduction GO:0003006 27 0.223
Mouse
cellular protein metabolic process GO:0044267 129 0.222
embryonic pectoral fin morphogenesis GO:0035118 24 0.220
epidermal cell fate specification GO:0009957 4 0.218
inner ear receptor cell fate commitment GO:0060120 4 0.215
regulation of nervous system development GO:0051960 90 0.215
Mouse
dopaminergic neuron differentiation GO:0071542 14 0.215
anterior commissure morphogenesis GO:0021960 3 0.214
cardiac muscle tissue development GO:0048738 48 0.213
Zebrafish
mesodermal cell differentiation GO:0048333 21 0.212
retina layer formation GO:0010842 24 0.212
Mouse
kupffer s vesicle development GO:0070121 50 0.207
death GO:0016265 121 0.207
positive regulation of cell proliferation GO:0008284 15 0.206
Mouse
positive regulation of transcription dna templated GO:0045893 57 0.206
Mouse Fly
single organism transport GO:0044765 206 0.204
endodermal cell differentiation GO:0035987 19 0.200
fin morphogenesis GO:0033334 53 0.199
epidermal cell differentiation GO:0009913 36 0.199
Zebrafish
axial mesodermal cell fate specification GO:0048327 3 0.196
pigmentation GO:0043473 85 0.195
exocrine system development GO:0035272 28 0.193
Zebrafish
negative regulation of cell differentiation GO:0045596 46 0.191
pancreatic d cell differentiation GO:0003311 2 0.191
Zebrafish
posterior lateral line system development GO:0048915 46 0.190
pronephric nephron development GO:0039019 14 0.190
Zebrafish
regulation of reproductive process GO:2000241 4 0.188
stem cell fate determination GO:0048867 1 0.185
renal tubule development GO:0061326 5 0.184
Mouse
cell differentiation in spinal cord GO:0021515 40 0.184
Zebrafish Mouse
neuron fate specification GO:0048665 20 0.182
Zebrafish
neural tube development GO:0021915 62 0.180
Zebrafish
regulation of cell death GO:0010941 103 0.179
negative regulation of rna biosynthetic process GO:1902679 45 0.178
Mouse Fly
negative regulation of transcription dna templated GO:0045892 45 0.177
Mouse Fly
cell projection morphogenesis GO:0048858 244 0.174
Zebrafish Mouse
hematopoietic progenitor cell differentiation GO:0002244 23 0.170
negative regulation of stem cell differentiation GO:2000737 2 0.168
neuroblast proliferation GO:0007405 2 0.166
distal tubule development GO:0072017 1 0.166
mesoderm morphogenesis GO:0048332 51 0.165
cellular nitrogen compound biosynthetic process GO:0044271 218 0.165
Mouse Fly
gland development GO:0048732 143 0.158
regulation of apoptotic process GO:0042981 98 0.157
epithelial tube morphogenesis GO:0060562 148 0.156
Mouse
neuron migration GO:0001764 22 0.156
Mouse
cardiac muscle cell differentiation GO:0055007 30 0.156
Zebrafish
regulation of mechanoreceptor differentiation GO:0045631 1 0.156
ventricular system development GO:0021591 12 0.154
Zebrafish
regulation of gastrulation GO:0010470 24 0.154
Mouse
mesenchyme development GO:0060485 127 0.151
regulation of anatomical structure morphogenesis GO:0022603 130 0.149
Mouse
proepicardium development GO:0003342 4 0.149
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.148
regulation of cellular component organization GO:0051128 86 0.147
photoreceptor cell differentiation GO:0046530 55 0.146
regulation of programmed cell death GO:0043067 101 0.145
neural retina development GO:0003407 49 0.144
Mouse
glial cell fate specification GO:0021780 4 0.144
endodermal cell fate commitment GO:0001711 18 0.143
negative regulation of cell development GO:0010721 26 0.142
protein metabolic process GO:0019538 183 0.142
forebrain neuron differentiation GO:0021879 14 0.142
central nervous system neuron axonogenesis GO:0021955 18 0.141
formation of primary germ layer GO:0001704 62 0.140
Mouse
abducens nucleus development GO:0021742 2 0.139
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.138
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.137
Zebrafish
positive regulation of nucleic acid templated transcription GO:1903508 57 0.136
Mouse Fly
cellular response to chemical stimulus GO:0070887 157 0.134
Rat
central nervous system neuron development GO:0021954 29 0.134
peripheral nervous system neuron differentiation GO:0048934 28 0.132
Zebrafish
spinal cord motor neuron differentiation GO:0021522 26 0.132
Zebrafish
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.131
embryonic appendage morphogenesis GO:0035113 30 0.130
embryonic skeletal system development GO:0048706 97 0.128
Mouse
response to mechanical stimulus GO:0009612 24 0.128
regulation of immune system process GO:0002682 34 0.127
positive regulation of developmental process GO:0051094 50 0.127
Mouse Worm
embryonic camera type eye development GO:0031076 29 0.126
Zebrafish
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.126
regulation of epithelial cell proliferation GO:0050678 3 0.125
pericardium morphogenesis GO:0003344 1 0.125
kidney morphogenesis GO:0060993 15 0.124
Mouse Rat
epithelial cell fate commitment GO:0072148 11 0.124
heart jogging GO:0003146 40 0.123
foregut morphogenesis GO:0007440 4 0.123
nephron tubule development GO:0072080 4 0.123
Mouse
anterior posterior axis specification GO:0009948 20 0.122
Mouse
chordate embryonic development GO:0043009 271 0.122
Zebrafish Mouse
pancreatic d cell development GO:0003324 1 0.120
Zebrafish
single organism metabolic process GO:0044710 217 0.119
sensory system development GO:0048880 76 0.118
inner ear morphogenesis GO:0042472 63 0.116
Zebrafish
spermatogenesis GO:0007283 7 0.115
tissue homeostasis GO:0001894 25 0.114
rhombomere development GO:0021546 19 0.113
eye photoreceptor cell development GO:0042462 30 0.113
retina development in camera type eye GO:0060041 146 0.113
Zebrafish Mouse
semicircular canal morphogenesis GO:0048752 18 0.112
Zebrafish
positive regulation of cellular biosynthetic process GO:0031328 68 0.112
Mouse Fly
endocardium formation GO:0060214 1 0.111
hematopoietic stem cell differentiation GO:0060218 20 0.110
nephric duct development GO:0072176 13 0.110
Mouse Rat
morphogenesis of an epithelium GO:0002009 333 0.109
Zebrafish Mouse
axonal fasciculation GO:0007413 11 0.108
Worm
positive regulation of glial cell differentiation GO:0045687 1 0.107
otic placode formation GO:0043049 23 0.105
regulation of cellular response to growth factor stimulus GO:0090287 35 0.104
epidermis development GO:0008544 48 0.103
Zebrafish
male gamete generation GO:0048232 7 0.102
auditory receptor cell fate determination GO:0042668 2 0.101
dendrite development GO:0016358 9 0.101
cell cell signaling involved in cell fate commitment GO:0045168 12 0.101
positive regulation of stem cell proliferation GO:2000648 1 0.099
eye photoreceptor cell differentiation GO:0001754 45 0.099
embryonic digestive tract morphogenesis GO:0048557 3 0.098
mitotic cell cycle GO:0000278 64 0.098
glial cell fate commitment GO:0021781 6 0.097
negative regulation of programmed cell death GO:0043069 58 0.095
endoderm formation GO:0001706 29 0.092
Mouse
otolith development GO:0048840 32 0.091
Zebrafish
establishment of localization GO:0051234 244 0.090
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.090
Mouse Fly
germ line stem cell maintenance GO:0030718 2 0.089
positive regulation of response to stimulus GO:0048584 80 0.089
regulation of endothelial cell differentiation GO:0045601 3 0.089
regulation of cell fate specification GO:0042659 20 0.088
mammillary body development GO:0021767 4 0.087
spinal cord association neuron differentiation GO:0021527 1 0.087
Mouse
stem cell proliferation GO:0072089 4 0.087
apoptotic process involved in development GO:1902742 2 0.086
retina morphogenesis in camera type eye GO:0060042 79 0.085
Mouse
negative regulation of signal transduction GO:0009968 94 0.085
pectoral fin development GO:0033339 50 0.085
ventral spinal cord interneuron differentiation GO:0021514 12 0.083
carboxylic acid catabolic process GO:0046395 3 0.082
regulation of protein metabolic process GO:0051246 56 0.082
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.081
myeloid cell homeostasis GO:0002262 56 0.081
aorta development GO:0035904 4 0.080
wnt signaling pathway GO:0016055 80 0.080
hormone transport GO:0009914 2 0.079
kidney epithelium development GO:0072073 23 0.078
Mouse Rat
glial cell differentiation GO:0010001 42 0.078
posttranscriptional regulation of gene expression GO:0010608 14 0.078
heart valve formation GO:0003188 4 0.078
regulation of heart morphogenesis GO:2000826 17 0.077
regulation of bmp signaling pathway GO:0030510 39 0.077
forebrain dorsal ventral pattern formation GO:0021798 1 0.076
pituitary gland development GO:0021983 16 0.076
phosphate containing compound metabolic process GO:0006796 108 0.076
negative regulation of apoptotic process GO:0043066 55 0.076
positive regulation of programmed cell death GO:0043068 29 0.075
regulation of biological quality GO:0065008 263 0.074
regulation of dendrite development GO:0050773 3 0.074
regeneration GO:0031099 91 0.074
cell migration GO:0016477 237 0.074
Mouse Worm
epithelial cell morphogenesis GO:0003382 2 0.073
regulation of endodermal cell differentiation GO:1903224 15 0.073
cellular response to organic substance GO:0071310 105 0.073
Rat
positive regulation of cell communication GO:0010647 56 0.073
peripheral nervous system development GO:0007422 55 0.072
Zebrafish
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.072
regulation of stem cell differentiation GO:2000736 4 0.071
limb bud formation GO:0060174 2 0.071
glomerulus morphogenesis GO:0072102 7 0.071
Zebrafish
fin development GO:0033333 77 0.070
pectoral fin morphogenesis GO:0035138 29 0.070
mesenchymal cell development GO:0014031 78 0.070
positive regulation of cell death GO:0010942 29 0.069
stem cell division GO:0017145 1 0.069
regulation of protein complex assembly GO:0043254 3 0.069
mesendoderm development GO:0048382 10 0.069
morphogenesis of an epithelial fold GO:0060571 1 0.067
skeletal system morphogenesis GO:0048705 102 0.065
Mouse
cerebellum formation GO:0021588 2 0.065
negative regulation of developmental process GO:0051093 65 0.065
cardiogenic plate morphogenesis GO:0003142 1 0.065
morphogenesis of embryonic epithelium GO:0016331 30 0.065
Zebrafish
cerebellum morphogenesis GO:0021587 10 0.065
Mouse
nucleocytoplasmic transport GO:0006913 4 0.064
enzyme linked receptor protein signaling pathway GO:0007167 106 0.064
limbic system development GO:0021761 16 0.064
regulation of notch signaling pathway GO:0008593 16 0.061
negative regulation of neurogenesis GO:0050768 20 0.061
reproductive process GO:0022414 40 0.060
Mouse Worm
endocardium morphogenesis GO:0003160 4 0.060
regulation of neuron projection development GO:0010975 40 0.060
intermediate mesoderm development GO:0048389 2 0.060
thyroid gland development GO:0030878 12 0.059
regulation of cellular protein metabolic process GO:0032268 52 0.058
paraxial mesoderm morphogenesis GO:0048340 2 0.057
lateral line system development GO:0048925 76 0.057
sensory organ development GO:0007423 393 0.057
Zebrafish Mouse Fly
positive regulation of neuron migration GO:2001224 2 0.057
positive regulation of notch signaling pathway GO:0045747 3 0.057
neuromast hair cell differentiation GO:0048886 12 0.057
regulation of mrna processing GO:0050684 3 0.056
determination of digestive tract left right asymmetry GO:0071907 10 0.056
negative regulation of multicellular organismal process GO:0051241 69 0.055
female sex differentiation GO:0046660 4 0.055
Mouse
sex differentiation GO:0007548 5 0.055
Mouse
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.055
regulation of jak stat cascade GO:0046425 3 0.054
multicellular organism reproduction GO:0032504 35 0.054
Worm
proximal tubule development GO:0072014 3 0.054
forebrain anterior posterior pattern specification GO:0021797 3 0.054
regulation of cell activation GO:0050865 1 0.053
atrioventricular valve development GO:0003171 11 0.053
regulation of heart growth GO:0060420 2 0.053
notochord cell differentiation GO:0060034 18 0.053
skeletal system development GO:0001501 181 0.052
Mouse
developmental growth GO:0048589 166 0.051
Zebrafish Mouse
regulation of mrna splicing via spliceosome GO:0048024 3 0.051
response to organic substance GO:0010033 153 0.050
Rat
heart formation GO:0060914 13 0.050
neural crest cell fate specification GO:0014036 5 0.050
neuroblast differentiation GO:0014016 1 0.049
positive regulation of cell cycle GO:0045787 3 0.049
mesenchymal cell differentiation GO:0048762 87 0.048
cellular amino acid metabolic process GO:0006520 7 0.048
proximal distal pattern formation GO:0009954 1 0.047
Fly
cellular response to endogenous stimulus GO:0071495 68 0.046
Rat
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.046
forebrain neuron development GO:0021884 7 0.046
regulation of cell cycle GO:0051726 52 0.045
regulation of canonical wnt signaling pathway GO:0060828 34 0.045
ear development GO:0043583 127 0.045
Zebrafish
neural crest cell differentiation GO:0014033 72 0.045
olfactory bulb development GO:0021772 4 0.045
sensory perception of chemical stimulus GO:0007606 3 0.044
cell fate determination GO:0001709 7 0.044
positive regulation of apoptotic process GO:0043065 29 0.043
lateral mesoderm development GO:0048368 23 0.043

lhx1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.137
disease of cellular proliferation DOID:14566 0 0.061