Danio rerio

48 known processes

mcm5

MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)

(Aliases: wu:fb34a06)

mcm5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule biosynthetic process GO:0034645 224 0.968
Yeast Fly
nitrogen compound metabolic process GO:0006807 319 0.926
Yeast Fly
rna metabolic process GO:0016070 219 0.926
Yeast
rna biosynthetic process GO:0032774 181 0.904
Yeast
cellular biosynthetic process GO:0044249 286 0.889
Yeast Fly
dna catabolic process GO:0006308 1 0.863
embryo development ending in birth or egg hatching GO:0009792 271 0.845
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.779
Yeast
aromatic compound biosynthetic process GO:0019438 217 0.774
Yeast
dna metabolic process GO:0006259 27 0.764
Yeast Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.742
Yeast
cellular aromatic compound metabolic process GO:0006725 295 0.735
Yeast Fly
heterocycle biosynthetic process GO:0018130 215 0.718
Yeast
cellular macromolecule metabolic process GO:0044260 391 0.711
Yeast Fly
nucleobase containing compound metabolic process GO:0006139 274 0.709
Yeast Fly
macromolecule biosynthetic process GO:0009059 227 0.709
Yeast Fly
biosynthetic process GO:0009058 294 0.670
Yeast Fly
mitotic dna integrity checkpoint GO:0044774 4 0.643
regulation of macromolecule biosynthetic process GO:0010556 225 0.592
Yeast
organic cyclic compound metabolic process GO:1901360 301 0.562
Yeast Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.552
Yeast Fly
larval development GO:0002164 2 0.541
organic cyclic compound biosynthetic process GO:1901362 223 0.537
Yeast
organic substance biosynthetic process GO:1901576 289 0.509
Yeast Fly
meiotic cell cycle process GO:1903046 3 0.486
Fly
regulation of dna replication GO:0006275 3 0.479
Yeast
negative regulation of cellular process GO:0048523 283 0.470
regulation of gene expression GO:0010468 265 0.465
Yeast
chromosome organization GO:0051276 31 0.448
Yeast Fly
dna biosynthetic process GO:0071897 3 0.446
positive regulation of cell cycle GO:0045787 3 0.442
digestive system development GO:0055123 289 0.439
regulation of transcription dna templated GO:0006355 213 0.436
Yeast
regulation of primary metabolic process GO:0080090 311 0.426
Yeast
single organism metabolic process GO:0044710 217 0.407
Yeast Fly
transcription dna templated GO:0006351 181 0.385
Yeast
heterocycle metabolic process GO:0046483 290 0.383
Yeast Fly
nucleic acid templated transcription GO:0097659 181 0.378
Yeast
mitotic recombination GO:0006312 2 0.376
cell fate commitment GO:0045165 99 0.367
nucleobase containing compound biosynthetic process GO:0034654 205 0.361
Yeast
response to stress GO:0006950 263 0.351
nucleic acid metabolic process GO:0090304 244 0.348
Yeast Fly
neuron differentiation GO:0030182 353 0.335
aging GO:0007568 2 0.327
lymphocyte activation GO:0046649 10 0.320
meiotic chromosome segregation GO:0045132 3 0.317
Fly
negative regulation of biological process GO:0048519 304 0.316
regulation of metabolic process GO:0019222 359 0.291
Yeast
hematopoietic or lymphoid organ development GO:0048534 191 0.275
meiotic nuclear division GO:0007126 4 0.266
Fly
reciprocal meiotic recombination GO:0007131 1 0.262
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.256
Yeast
chordate embryonic development GO:0043009 271 0.255
regulation of cellular metabolic process GO:0031323 320 0.254
Yeast
organelle organization GO:0006996 227 0.242
Yeast Fly
macromolecule modification GO:0043412 111 0.240
neuron development GO:0048666 262 0.239
cellular protein modification process GO:0006464 100 0.231
gene expression GO:0010467 252 0.229
Yeast
regulation of biosynthetic process GO:0009889 250 0.226
Yeast
regulation of signal transduction GO:0009966 225 0.212
regulation of rna biosynthetic process GO:2001141 213 0.212
Yeast
negative regulation of nucleic acid templated transcription GO:1903507 45 0.211
Yeast
sensory organ development GO:0007423 393 0.211
immune system development GO:0002520 191 0.210
maintenance of dna repeat elements GO:0043570 2 0.208
negative regulation of cellular biosynthetic process GO:0031327 55 0.207
Yeast
camera type eye development GO:0043010 222 0.207
response to metal ion GO:0010038 34 0.203
single organism organelle organization GO:1902589 199 0.197
Fly
positive regulation of chromatin modification GO:1903310 1 0.193
protein acetylation GO:0006473 2 0.192
regulation of mitotic cell cycle GO:0007346 25 0.190
hemopoiesis GO:0030097 183 0.188
cellular protein metabolic process GO:0044267 129 0.188
regulation of macromolecule metabolic process GO:0060255 317 0.187
Yeast
cell proliferation GO:0008283 80 0.183
phosphate containing compound metabolic process GO:0006796 108 0.183
Yeast
response to abiotic stimulus GO:0009628 122 0.181
positive regulation of cellular metabolic process GO:0031325 94 0.179
Yeast
heart development GO:0007507 313 0.177
response to nitrogen compound GO:1901698 19 0.177
b cell differentiation GO:0030183 1 0.168
single organism biosynthetic process GO:0044711 71 0.167
Yeast Fly
cell surface receptor signaling pathway GO:0007166 325 0.165
leukocyte differentiation GO:0002521 25 0.164
embryonic organ development GO:0048568 381 0.159
cellular response to stress GO:0033554 62 0.159
Yeast
vasculature development GO:0001944 278 0.158
protein metabolic process GO:0019538 183 0.156
regulation of cell cycle GO:0051726 52 0.156
reciprocal dna recombination GO:0035825 1 0.155
Fly
cell activation GO:0001775 16 0.154
angiogenesis GO:0001525 158 0.153
cell projection organization GO:0030030 284 0.153
regulation of nuclease activity GO:0032069 1 0.151
regulation of meiotic cell cycle GO:0051445 1 0.149
b cell activation GO:0042113 2 0.146
stem cell development GO:0048864 82 0.143
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.143
Yeast
regulation of nitrogen compound metabolic process GO:0051171 251 0.143
Yeast
mitotic cell cycle checkpoint GO:0007093 5 0.136
cellular response to dna damage stimulus GO:0006974 24 0.135
Yeast
cellular component assembly involved in morphogenesis GO:0010927 107 0.135
dna methylation on cytosine GO:0032776 3 0.132
centrosome cycle GO:0007098 1 0.132
regulation of cellular biosynthetic process GO:0031326 245 0.130
Yeast
mitotic dna damage checkpoint GO:0044773 4 0.130
camera type eye morphogenesis GO:0048593 108 0.123
negative regulation of biosynthetic process GO:0009890 55 0.119
Yeast
digestive tract development GO:0048565 265 0.118
retina development in camera type eye GO:0060041 146 0.117
sex determination GO:0007530 1 0.114
mesenchymal cell development GO:0014031 78 0.112
retina morphogenesis in camera type eye GO:0060042 79 0.111
microtubule organizing center organization GO:0031023 1 0.111
protein modification process GO:0036211 100 0.110
negative regulation of cell cycle GO:0045786 14 0.109
regulation of dna catabolic process GO:1903624 1 0.108
neuroblast proliferation GO:0007405 2 0.108
cell cycle GO:0007049 93 0.107
negative regulation of mitotic cell cycle GO:0045930 11 0.106
apoptotic process GO:0006915 116 0.106
eye development GO:0001654 277 0.106
phosphorylation GO:0016310 69 0.105
cellular response to chemical stimulus GO:0070887 157 0.104
neuron projection development GO:0031175 180 0.102
immunoglobulin production GO:0002377 1 0.102
regulation of histone h3 k9 methylation GO:0051570 2 0.101
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.099
Yeast
leukocyte activation GO:0045321 12 0.099
negative regulation of gene expression GO:0010629 65 0.098
Yeast
organelle fission GO:0048285 23 0.097
Fly
negative regulation of chromosome organization GO:2001251 1 0.096
neural crest cell differentiation GO:0014033 72 0.093
locomotion GO:0040011 313 0.093
growth GO:0040007 174 0.093
negative regulation of cell communication GO:0010648 96 0.093
protein localization to nucleus GO:0034504 3 0.093
peptidyl serine modification GO:0018209 2 0.092
regulation of deoxyribonuclease activity GO:0032070 1 0.091
response to other organism GO:0051707 97 0.090
leukocyte proliferation GO:0070661 1 0.088
double strand break repair via nonhomologous end joining GO:0006303 1 0.087
negative regulation of apoptotic process GO:0043066 55 0.086
regulation of cellular component organization GO:0051128 86 0.086
negative regulation of rna metabolic process GO:0051253 48 0.084
Yeast
response to organic substance GO:0010033 153 0.082
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.081
regulation of establishment of protein localization GO:0070201 4 0.081
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.081
multi organism process GO:0051704 134 0.081
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.079
Yeast
regulation of heart growth GO:0060420 2 0.077
regulation of catalytic activity GO:0050790 55 0.076
negative regulation of response to stimulus GO:0048585 104 0.075
regulation of programmed cell death GO:0043067 101 0.075
positive regulation of biological process GO:0048518 253 0.074
Yeast
stem cell differentiation GO:0048863 117 0.073
mesenchymal cell differentiation GO:0048762 87 0.072
response to ionizing radiation GO:0010212 6 0.072
cell morphogenesis GO:0000902 289 0.071
covalent chromatin modification GO:0016569 20 0.070
establishment of localization GO:0051234 244 0.070
stem cell maintenance GO:0019827 4 0.070
regulation of rna metabolic process GO:0051252 224 0.069
Yeast
double strand break repair via homologous recombination GO:0000724 1 0.069
Yeast
g1 s transition of mitotic cell cycle GO:0000082 1 0.069
negative regulation of rna biosynthetic process GO:1902679 45 0.067
Yeast
centrosome organization GO:0051297 1 0.067
mononuclear cell proliferation GO:0032943 1 0.066
generation of neurons GO:0048699 385 0.066
regulation of multicellular organism growth GO:0040014 4 0.065
dna alkylation GO:0006305 8 0.065
response to biotic stimulus GO:0009607 97 0.065
immune system process GO:0002376 241 0.065
meiosis i GO:0007127 1 0.065
Fly
cell migration GO:0016477 237 0.064
developmental growth GO:0048589 166 0.063
negative regulation of cellular metabolic process GO:0031324 77 0.063
Yeast
positive regulation of protein metabolic process GO:0051247 23 0.063
pancreas development GO:0031016 84 0.062
negative regulation of macromolecule metabolic process GO:0010605 76 0.061
Yeast
cellular component movement GO:0006928 335 0.061
regulation of cell proliferation GO:0042127 37 0.061
positive regulation of catalytic activity GO:0043085 25 0.061
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.060
Yeast
positive regulation of biosynthetic process GO:0009891 68 0.060
Yeast
regulation of protein transport GO:0051223 3 0.060
histone h3 k4 methylation GO:0051568 2 0.060
telomere maintenance GO:0000723 1 0.060
regulation of mitotic cell cycle phase transition GO:1901990 8 0.059
response to chemical GO:0042221 320 0.059
negative regulation of dna metabolic process GO:0051053 4 0.059
negative regulation of metabolic process GO:0009892 86 0.057
Yeast
heart morphogenesis GO:0003007 156 0.057
phosphorus metabolic process GO:0006793 109 0.057
Yeast
mesenchyme development GO:0060485 127 0.057
spindle assembly GO:0051225 2 0.057
dna replication GO:0006260 6 0.056
Yeast Fly
negative regulation of programmed cell death GO:0043069 58 0.053
cellular component morphogenesis GO:0032989 336 0.053
response to external biotic stimulus GO:0043207 97 0.053
response to amino acid GO:0043200 2 0.052
regulation of cell cycle process GO:0010564 20 0.052
regulation of multicellular organismal process GO:0051239 277 0.051
methylation GO:0032259 22 0.051
negative regulation of histone methylation GO:0031061 1 0.050
blood vessel morphogenesis GO:0048514 216 0.049
negative regulation of kinase activity GO:0033673 4 0.048
nuclear division GO:0000280 23 0.048
Fly
regulation of proteolysis GO:0030162 24 0.047
response to drug GO:0042493 3 0.047
cellular amine metabolic process GO:0044106 2 0.046
embryonic organ morphogenesis GO:0048562 274 0.046
lymphocyte proliferation GO:0046651 1 0.046
ribonucleoside monophosphate catabolic process GO:0009158 4 0.046
Yeast
negative regulation of cell death GO:0060548 60 0.045
death GO:0016265 121 0.045
negative regulation of cellular component organization GO:0051129 16 0.045
epithelial tube morphogenesis GO:0060562 148 0.045
response to inorganic substance GO:0010035 38 0.045
cellular response to organic substance GO:0071310 105 0.044
organelle assembly GO:0070925 110 0.044
blood vessel development GO:0001568 246 0.044
positive regulation of nuclease activity GO:0032075 1 0.043
lymphocyte differentiation GO:0030098 9 0.043
multicellular organism growth GO:0035264 4 0.043
macromolecular complex subunit organization GO:0043933 74 0.042
Yeast
regulation of apoptotic process GO:0042981 98 0.041
regulation of hydrolase activity GO:0051336 28 0.041
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.041
organonitrogen compound metabolic process GO:1901564 74 0.041
Yeast
dna integrity checkpoint GO:0031570 6 0.041
amine metabolic process GO:0009308 2 0.041
negative regulation of cell cycle process GO:0010948 9 0.040
positive regulation of metabolic process GO:0009893 108 0.040
Yeast
developmental process involved in reproduction GO:0003006 27 0.040
programmed cell death GO:0012501 119 0.040
positive regulation of muscle organ development GO:0048636 1 0.040
urogenital system development GO:0001655 97 0.039
centrosome duplication GO:0051298 1 0.039
dna damage checkpoint GO:0000077 6 0.039
intracellular signal transduction GO:0035556 85 0.038
deoxyribonucleotide metabolic process GO:0009262 1 0.038
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.037
Yeast
eye morphogenesis GO:0048592 144 0.037
mitotic cell cycle process GO:1903047 48 0.037
embryonic heart tube development GO:0035050 133 0.037
female meiotic division GO:0007143 2 0.036
carboxylic acid metabolic process GO:0019752 22 0.036
dna repair GO:0006281 6 0.036
Yeast
cell death GO:0008219 121 0.036
mitotic cell cycle phase transition GO:0044772 9 0.036
dna recombination GO:0006310 5 0.036
Yeast Fly
system process GO:0003008 185 0.035
skeletal system development GO:0001501 181 0.035
atp catabolic process GO:0006200 4 0.035
Yeast
cellular component biogenesis GO:0044085 178 0.035
Yeast
cell division GO:0051301 20 0.034
positive regulation of cell proliferation GO:0008284 15 0.034
cell cycle checkpoint GO:0000075 7 0.034
protein phosphorylation GO:0006468 47 0.034
nuclear transport GO:0051169 4 0.034
neural crest cell development GO:0014032 62 0.034
glial cell differentiation GO:0010001 42 0.034
regulation of cellular ketone metabolic process GO:0010565 7 0.033
organophosphate biosynthetic process GO:0090407 23 0.033
chromatin organization GO:0006325 22 0.033
Yeast
deoxyribonucleotide biosynthetic process GO:0009263 1 0.033
tube morphogenesis GO:0035239 349 0.033
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.033
exocrine pancreas development GO:0031017 28 0.032
response to endogenous stimulus GO:0009719 83 0.032
response to steroid hormone GO:0048545 35 0.032
pyrimidine containing compound metabolic process GO:0072527 3 0.032
response to external stimulus GO:0009605 264 0.032
metal ion transport GO:0030001 58 0.032
telomere organization GO:0032200 1 0.031
cell part morphogenesis GO:0032990 246 0.031
small molecule metabolic process GO:0044281 77 0.031
Yeast
cell morphogenesis involved in differentiation GO:0000904 195 0.031
single organism localization GO:1902578 225 0.030
cell cycle arrest GO:0007050 1 0.030
cytoskeleton dependent cytokinesis GO:0061640 3 0.030
negative regulation of protein metabolic process GO:0051248 16 0.029
positive regulation of dna metabolic process GO:0051054 1 0.029
transport GO:0006810 220 0.029
organ regeneration GO:0031100 1 0.029
mitotic cell cycle GO:0000278 64 0.029
chromatin modification GO:0016568 21 0.029
Yeast
meiotic cell cycle GO:0051321 5 0.028
Fly
protein complex localization GO:0031503 1 0.028
positive regulation of immune system process GO:0002684 17 0.028
mitotic metaphase plate congression GO:0007080 1 0.028
intra s dna damage checkpoint GO:0031573 1 0.027
cell cycle g1 s phase transition GO:0044843 1 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
protein localization GO:0008104 40 0.027
gland development GO:0048732 143 0.027
regulation of developmental process GO:0050793 247 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.027
Yeast
nucleoside phosphate biosynthetic process GO:1901293 21 0.027
cell cycle process GO:0022402 53 0.027
Yeast Fly
stem cell proliferation GO:0072089 4 0.027
behavior GO:0007610 74 0.027
sister chromatid cohesion GO:0007062 2 0.027
gliogenesis GO:0042063 45 0.027
hepaticobiliary system development GO:0061008 98 0.027
regulation of cellular protein metabolic process GO:0032268 52 0.026
cellular macromolecular complex assembly GO:0034622 24 0.026
Yeast
somatic cell dna recombination GO:0016444 1 0.026
regulation of neurogenesis GO:0050767 87 0.026
regulation of response to stimulus GO:0048583 269 0.026
signal transduction GO:0007165 455 0.026
positive regulation of immune effector process GO:0002699 3 0.026
regulation of protein import into nucleus GO:0042306 2 0.026
axonogenesis GO:0007409 152 0.026
pronuclear migration GO:0035046 1 0.026
head development GO:0060322 303 0.025
mitotic sister chromatid segregation GO:0000070 6 0.025
peptidyl serine phosphorylation GO:0018105 1 0.025
regulation of cell activation GO:0050865 1 0.025
response to oxygen containing compound GO:1901700 55 0.025
nucleoside monophosphate catabolic process GO:0009125 4 0.025
Yeast
regulation of protein catabolic process GO:0042176 1 0.024
apoptotic signaling pathway GO:0097190 23 0.024
cell motility GO:0048870 244 0.024
nucleic acid phosphodiester bond hydrolysis GO:0090305 6 0.024
gene silencing GO:0016458 4 0.024
Yeast
anatomical structure homeostasis GO:0060249 36 0.024
segment specification GO:0007379 12 0.024
vesicle mediated transport GO:0016192 22 0.024
specification of symmetry GO:0009799 204 0.024
myofibril assembly GO:0030239 48 0.024
negative regulation of histone modification GO:0031057 1 0.024
regulation of dna recombination GO:0000018 2 0.024
regulation of protein metabolic process GO:0051246 56 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
lateral inhibition GO:0046331 1 0.023
regulation of dna metabolic process GO:0051052 11 0.023
Yeast
meiotic spindle organization GO:0000212 1 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.023
Yeast
negative regulation of signal transduction GO:0009968 94 0.022
negative regulation of transcription dna templated GO:0045892 45 0.022
Yeast
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.022
Yeast
heart process GO:0003015 71 0.022
regulation of molecular function GO:0065009 70 0.022
macromolecule methylation GO:0043414 19 0.022
negative regulation of protein kinase activity GO:0006469 4 0.022
regulation of stem cell proliferation GO:0072091 2 0.022
cognition GO:0050890 1 0.022
microtubule based process GO:0007017 60 0.022
histone phosphorylation GO:0016572 2 0.022
regeneration GO:0031099 91 0.022
double strand break repair GO:0006302 3 0.021
Yeast
negative regulation of cell division GO:0051782 4 0.021
antimicrobial humoral response GO:0019730 2 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
mitotic spindle organization GO:0007052 5 0.021
production of molecular mediator of immune response GO:0002440 2 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.020
rna processing GO:0006396 25 0.020
histone methylation GO:0016571 13 0.020
positive regulation of cellular process GO:0048522 201 0.020
Yeast
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
positive regulation of chromosome organization GO:2001252 1 0.020
maintenance of location GO:0051235 4 0.020
reproductive process GO:0022414 40 0.020
positive regulation of cellular protein metabolic process GO:0032270 22 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
cilium morphogenesis GO:0060271 85 0.019
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.019
positive regulation of cell activation GO:0050867 1 0.019
cytokinesis GO:0000910 3 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
embryonic digestive tract morphogenesis GO:0048557 3 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
Yeast
positive regulation of apoptotic process GO:0043065 29 0.019
protein secretion GO:0009306 1 0.019
inner ear receptor cell fate commitment GO:0060120 4 0.019
protein targeting to nucleus GO:0044744 3 0.018
regulation of cell cycle phase transition GO:1901987 8 0.018
heterocycle catabolic process GO:0046700 15 0.018
Yeast
phagocytosis GO:0006909 3 0.018
embryonic heart tube morphogenesis GO:0003143 108 0.018
synapsis GO:0007129 1 0.018
determination of heart left right asymmetry GO:0061371 117 0.017
axon development GO:0061564 166 0.017
cellular response to oxygen containing compound GO:1901701 20 0.017
oxoacid metabolic process GO:0043436 31 0.017
positive regulation of striated muscle tissue development GO:0045844 1 0.017
negative regulation of developmental process GO:0051093 65 0.017
cellular component disassembly GO:0022411 1 0.017
neuron fate specification GO:0048665 20 0.017
localization of cell GO:0051674 244 0.017
response to organic cyclic compound GO:0014070 51 0.017
regulation of biological quality GO:0065008 263 0.017
liver development GO:0001889 96 0.016
mitotic nuclear division GO:0007067 18 0.016
cellular response to organic cyclic compound GO:0071407 38 0.016
rna localization GO:0006403 4 0.016
purine containing compound metabolic process GO:0072521 29 0.016
Yeast
brain development GO:0007420 293 0.016
regulation of cardiac muscle tissue development GO:0055024 1 0.016
heart looping GO:0001947 94 0.016
negative regulation of signaling GO:0023057 96 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
regulation of glial cell differentiation GO:0045685 4 0.016
regulation of cell communication GO:0010646 232 0.016
positive regulation of molecular function GO:0044093 33 0.016
cellular ketone metabolic process GO:0042180 11 0.016
internal protein amino acid acetylation GO:0006475 2 0.015
positive regulation of hydrolase activity GO:0051345 13 0.015
dna methylation GO:0006306 8 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
epithelial cell morphogenesis GO:0003382 2 0.015
protein import into nucleus GO:0006606 3 0.015
segmentation GO:0035282 97 0.015
cilium organization GO:0044782 71 0.015
sensory organ morphogenesis GO:0090596 200 0.015
regulation of nervous system development GO:0051960 90 0.015
heart contraction GO:0060047 71 0.015
pyrimidine containing compound biosynthetic process GO:0072528 2 0.015
positive regulation of programmed cell death GO:0043068 29 0.015
multicellular organismal homeostasis GO:0048871 29 0.015
response to uv GO:0009411 3 0.015
regulation of cell development GO:0060284 100 0.015
circulatory system process GO:0003013 87 0.015
cell cycle phase transition GO:0044770 9 0.015
positive regulation of gene expression GO:0010628 71 0.014
Yeast
positive regulation of cell division GO:0051781 2 0.014
positive regulation of catabolic process GO:0009896 4 0.014
regulation of epithelial to mesenchymal transition GO:0010717 3 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
reflex GO:0060004 2 0.014
immunoglobulin mediated immune response GO:0016064 3 0.014
positive regulation of transport GO:0051050 2 0.014
catabolic process GO:0009056 32 0.014
Yeast
striated muscle tissue development GO:0014706 110 0.014
neuron projection morphogenesis GO:0048812 161 0.014
positive regulation of endopeptidase activity GO:0010950 10 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
determination of bilateral symmetry GO:0009855 204 0.014
peptidyl amino acid modification GO:0018193 16 0.014
chromosome organization involved in meiosis GO:0070192 1 0.014
protein methylation GO:0006479 13 0.014
single organism intracellular transport GO:1902582 25 0.014
regulation of nuclear division GO:0051783 9 0.014
regulation of chromosome segregation GO:0051983 1 0.013
dna modification GO:0006304 8 0.013
regulation of cellular component movement GO:0051270 55 0.013
cellular response to external stimulus GO:0071496 2 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
Yeast
regulation of immune system process GO:0002682 34 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
protein acylation GO:0043543 3 0.013
negative regulation of nervous system development GO:0051961 22 0.013
positive regulation of striated muscle cell differentiation GO:0051155 1 0.013
water soluble vitamin metabolic process GO:0006767 1 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
positive regulation of cell death GO:0010942 29 0.012
positive regulation of glial cell differentiation GO:0045687 1 0.012
cardiac muscle cell differentiation GO:0055007 30 0.012
positive regulation of histone modification GO:0031058 1 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
cell aging GO:0007569 2 0.012
sister chromatid segregation GO:0000819 6 0.012
germ cell development GO:0007281 22 0.012
neural retina development GO:0003407 49 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
negative regulation of neutrophil chemotaxis GO:0090024 3 0.012
regulation of tissue remodeling GO:0034103 2 0.012
regulation of peptidase activity GO:0052547 23 0.012
histone h3 k9 methylation GO:0051567 5 0.012
cell death in response to oxidative stress GO:0036473 2 0.012

mcm5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
large intestine cancer DOID:5672 0 0.054
gastrointestinal system cancer DOID:3119 0 0.054
intestinal cancer DOID:10155 0 0.054
cancer DOID:162 0 0.054
disease of cellular proliferation DOID:14566 0 0.054
organ system cancer DOID:0050686 0 0.054
disease of mental health DOID:150 0 0.036
developmental disorder of mental health DOID:0060037 0 0.036
colorectal cancer DOID:9256 0 0.017
bone development disease DOID:0080006 0 0.013
bone disease DOID:0080001 0 0.013
disease of anatomical entity DOID:7 0 0.013
dysostosis DOID:1934 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
nervous system disease DOID:863 0 0.012