Danio rerio

0 known processes

tsku

tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)

(Aliases: wu:fd51d02,fd51d02,zgc:56201)

tsku biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of response to stimulus GO:0048583 269 0.197
Mouse
determination of left right symmetry GO:0007368 179 0.185
embryonic organ morphogenesis GO:0048562 274 0.092
regulation of stem cell differentiation GO:2000736 4 0.072
connective tissue development GO:0061448 99 0.071
regulation of epithelial cell proliferation GO:0050678 3 0.071
fat soluble vitamin metabolic process GO:0006775 4 0.060
heart development GO:0007507 313 0.060
determination of bilateral symmetry GO:0009855 204 0.059
stem cell maintenance GO:0019827 4 0.058
embryonic heart tube morphogenesis GO:0003143 108 0.056
skeletal system development GO:0001501 181 0.055
multicellular organismal macromolecule metabolic process GO:0044259 2 0.055
eye development GO:0001654 277 0.051
Mouse
regulation of developmental process GO:0050793 247 0.049
sensory organ morphogenesis GO:0090596 200 0.048
Mouse
ear development GO:0043583 127 0.047
death GO:0016265 121 0.046
carboxylic acid metabolic process GO:0019752 22 0.045
maintenance of location GO:0051235 4 0.044
regulation of myotube differentiation GO:0010830 2 0.043
regulation of reproductive process GO:2000241 4 0.039
tissue remodeling GO:0048771 4 0.039
lipid storage GO:0019915 1 0.038
regulation of synapse organization GO:0050807 3 0.038
regulation of multicellular organismal process GO:0051239 277 0.037
regulation of cell activation GO:0050865 1 0.036
multicellular organism growth GO:0035264 4 0.036
larval development GO:0002164 2 0.034
sensory organ development GO:0007423 393 0.033
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.032
fin development GO:0033333 77 0.031
lateral inhibition GO:0046331 1 0.030
regulation of signal transduction GO:0009966 225 0.029
Mouse
specification of symmetry GO:0009799 204 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
multicellular organismal response to stress GO:0033555 2 0.029
skeletal system morphogenesis GO:0048705 102 0.029
embryonic organ development GO:0048568 381 0.029
growth GO:0040007 174 0.029
response to nutrient GO:0007584 3 0.028
embryonic limb morphogenesis GO:0030326 2 0.028
cell morphogenesis GO:0000902 289 0.027
Mouse
embryonic heart tube development GO:0035050 133 0.026
organic acid metabolic process GO:0006082 31 0.026
regulation of skeletal muscle tissue development GO:0048641 4 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
organic substance biosynthetic process GO:1901576 289 0.026
regulation of mesenchymal cell proliferation GO:0010464 1 0.025
single organism localization GO:1902578 225 0.025
single organism organelle organization GO:1902589 199 0.024
synaptic growth at neuromuscular junction GO:0051124 2 0.024
response to monosaccharide GO:0034284 3 0.024
collagen metabolic process GO:0032963 2 0.024
cellular carbohydrate metabolic process GO:0044262 4 0.024
determination of heart left right asymmetry GO:0061371 117 0.024
regulation of tube size GO:0035150 2 0.023
cellular component assembly involved in morphogenesis GO:0010927 107 0.023
response to external stimulus GO:0009605 264 0.023
apoptotic process GO:0006915 116 0.023
regulation of blood vessel size GO:0050880 2 0.023
regulation of synapse assembly GO:0051963 3 0.022
response to glucose GO:0009749 3 0.022
alpha amino acid metabolic process GO:1901605 3 0.022
response to hexose GO:0009746 3 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.022
neuron differentiation GO:0030182 353 0.021
Mouse
heterocycle metabolic process GO:0046483 290 0.021
response to corticosteroid GO:0031960 1 0.021
sensory perception of chemical stimulus GO:0007606 3 0.021
response to carbohydrate GO:0009743 3 0.021
positive regulation of cellular process GO:0048522 201 0.021
cell death GO:0008219 121 0.020
ear morphogenesis GO:0042471 64 0.020
oxoacid metabolic process GO:0043436 31 0.020
phagocytosis GO:0006909 3 0.020
inner ear morphogenesis GO:0042472 63 0.020
regionalization GO:0003002 274 0.020
cell cell signaling involved in cell fate commitment GO:0045168 12 0.019
positive regulation of synapse assembly GO:0051965 1 0.019
cell projection morphogenesis GO:0048858 244 0.019
Mouse
positive regulation of carbohydrate metabolic process GO:0045913 1 0.018
eye morphogenesis GO:0048592 144 0.018
Mouse
programmed cell death GO:0012501 119 0.018
nephron development GO:0072006 31 0.018
cellular protein catabolic process GO:0044257 4 0.018
response to chemical GO:0042221 320 0.018
fat soluble vitamin biosynthetic process GO:0042362 2 0.017
regulation of microtubule cytoskeleton organization GO:0070507 3 0.017
regulation of cell death GO:0010941 103 0.017
negative regulation of muscle cell differentiation GO:0051148 1 0.017
bone development GO:0060348 14 0.017
camera type eye development GO:0043010 222 0.017
Mouse
cellular biosynthetic process GO:0044249 286 0.017
establishment of blood brain barrier GO:0060856 2 0.017
regulation of primary metabolic process GO:0080090 311 0.017
compound eye development GO:0048749 2 0.017
isoprenoid metabolic process GO:0006720 15 0.017
digestive system development GO:0055123 289 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
secondary metabolic process GO:0019748 3 0.016
embryonic eye morphogenesis GO:0048048 30 0.016
retinoid metabolic process GO:0001523 15 0.016
appendage morphogenesis GO:0035107 56 0.016
peptide metabolic process GO:0006518 1 0.016
response to glucocorticoid GO:0051384 1 0.016
fin morphogenesis GO:0033334 53 0.016
negative regulation of bmp signaling pathway GO:0030514 13 0.016
tube closure GO:0060606 1 0.015
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.015
regulation of establishment of planar polarity GO:0090175 4 0.015
membrane invagination GO:0010324 1 0.015
embryonic skeletal system morphogenesis GO:0048704 93 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
Mouse
hormone secretion GO:0046879 2 0.015
negative regulation of stem cell differentiation GO:2000737 2 0.015
appendage development GO:0048736 80 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
neuron projection morphogenesis GO:0048812 161 0.015
Mouse
intracellular signal transduction GO:0035556 85 0.015
aging GO:0007568 2 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
cellular amino acid biosynthetic process GO:0008652 2 0.014
small molecule metabolic process GO:0044281 77 0.014
heart looping GO:0001947 94 0.014
cellular aldehyde metabolic process GO:0006081 4 0.014
behavior GO:0007610 74 0.014
regulation of biological quality GO:0065008 263 0.014
central nervous system development GO:0007417 387 0.014
Mouse
gland development GO:0048732 143 0.014
pectoral fin development GO:0033339 50 0.014
endoderm formation GO:0001706 29 0.014
positive regulation of cell activation GO:0050867 1 0.014
vitamin a metabolic process GO:0006776 1 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
collagen biosynthetic process GO:0032964 2 0.013
zymogen activation GO:0031638 3 0.013
cellular amine metabolic process GO:0044106 2 0.013
response to stress GO:0006950 263 0.013
muscle organ development GO:0007517 101 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
mononuclear cell proliferation GO:0032943 1 0.013
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.013
regulation of programmed cell death GO:0043067 101 0.013
multi organism process GO:0051704 134 0.013
cellular response to external stimulus GO:0071496 2 0.013
specification of organ axis polarity GO:0010084 2 0.013
striated muscle tissue development GO:0014706 110 0.013
positive regulation of biological process GO:0048518 253 0.013
tube morphogenesis GO:0035239 349 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
regulation of cellular metabolic process GO:0031323 320 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
cartilage development GO:0051216 96 0.012
bone remodeling GO:0046849 2 0.012
cellular component biogenesis GO:0044085 178 0.012
multicellular organismal metabolic process GO:0044236 2 0.012
regulation of chondrocyte differentiation GO:0032330 1 0.012
bmp signaling pathway GO:0030509 52 0.012
kidney development GO:0001822 92 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
pronephros development GO:0048793 69 0.012
organelle organization GO:0006996 227 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
pyrimidine containing compound metabolic process GO:0072527 3 0.012
heart morphogenesis GO:0003007 156 0.012
adult behavior GO:0030534 2 0.012
regulation of biomineral tissue development GO:0070167 2 0.012
striated muscle cell differentiation GO:0051146 129 0.012
macromolecule localization GO:0033036 54 0.011
spermatid development GO:0007286 2 0.011
rna metabolic process GO:0016070 219 0.011
cardiac muscle tissue development GO:0048738 48 0.011
apoptotic signaling pathway GO:0097190 23 0.011
locomotion GO:0040011 313 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
mesenchymal cell proliferation GO:0010463 1 0.011
transcription dna templated GO:0006351 181 0.011
cellular amide metabolic process GO:0043603 4 0.011
protein metabolic process GO:0019538 183 0.011
cellular response to starvation GO:0009267 1 0.011
terpenoid metabolic process GO:0006721 15 0.011
response to vitamin GO:0033273 3 0.011
lens fiber cell morphogenesis GO:0070309 3 0.011
regulation of hormone secretion GO:0046883 2 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
regulation of calcium ion transport GO:0051924 2 0.011
positive regulation of catabolic process GO:0009896 4 0.011
single organism metabolic process GO:0044710 217 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
morphogenesis of an epithelial fold GO:0060571 1 0.011
regulation of cellular component organization GO:0051128 86 0.011
localization of cell GO:0051674 244 0.011
cardiac muscle cell differentiation GO:0055007 30 0.011
type b pancreatic cell development GO:0003323 4 0.011
cell cycle arrest GO:0007050 1 0.011
regulation of signaling GO:0023051 235 0.011
Mouse
homeostatic process GO:0042592 142 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
growth plate cartilage development GO:0003417 2 0.010
biosynthetic process GO:0009058 294 0.010
regulation of protein catabolic process GO:0042176 1 0.010
regulation of muscle organ development GO:0048634 9 0.010
embryonic skeletal joint development GO:0072498 3 0.010
proximal distal pattern formation GO:0009954 1 0.010
negative regulation of muscle tissue development GO:1901862 2 0.010
establishment of localization GO:0051234 244 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.010
chondrocyte development GO:0002063 4 0.010
developmental growth GO:0048589 166 0.010
chordate embryonic development GO:0043009 271 0.010
mesendoderm development GO:0048382 10 0.010
cell part morphogenesis GO:0032990 246 0.010
Mouse
centrosome organization GO:0051297 1 0.010
negative regulation of rna metabolic process GO:0051253 48 0.010

tsku disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.018
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018
inherited metabolic disorder DOID:655 0 0.015
disease of metabolism DOID:0014667 0 0.015
bone development disease DOID:0080006 0 0.015
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014