Danio rerio

0 known processes

ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

(Aliases: wu:fb33h05,zgc:92209)

ndufs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 271 0.618
Worm
cellular respiration GO:0045333 3 0.542
Human
carboxylic acid catabolic process GO:0046395 3 0.496
locomotion GO:0040011 313 0.356
atp synthesis coupled electron transport GO:0042773 1 0.342
electron transport chain GO:0022900 2 0.323
aging GO:0007568 2 0.319
Worm
organic acid catabolic process GO:0016054 3 0.251
lipid catabolic process GO:0016042 4 0.226
response to drug GO:0042493 3 0.215
respiratory electron transport chain GO:0022904 2 0.195
fatty acid beta oxidation GO:0006635 1 0.179
small molecule metabolic process GO:0044281 77 0.168
Human
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.159
nucleoside monophosphate catabolic process GO:0009125 4 0.156
atp catabolic process GO:0006200 4 0.156
larval development GO:0002164 2 0.128
Worm
nucleobase containing compound metabolic process GO:0006139 274 0.110
Human
mitochondrial electron transport nadh to ubiquinone GO:0006120 1 0.107
mitochondrion morphogenesis GO:0070584 2 0.103
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.103
organonitrogen compound metabolic process GO:1901564 74 0.100
Human
single organism metabolic process GO:0044710 217 0.097
Human
establishment of localization GO:0051234 244 0.096
ribonucleoside monophosphate catabolic process GO:0009158 4 0.090
purine ribonucleoside monophosphate metabolic process GO:0009167 5 0.084
Human
monocarboxylic acid catabolic process GO:0072329 3 0.083
maintenance of location GO:0051235 4 0.077
fatty acid catabolic process GO:0009062 1 0.070
organic cyclic compound metabolic process GO:1901360 301 0.065
Human
purine nucleoside monophosphate catabolic process GO:0009128 4 0.063
lipid oxidation GO:0034440 1 0.062
lipid storage GO:0019915 1 0.062
single organism organelle organization GO:1902589 199 0.060
phagocytosis GO:0006909 3 0.060
regulation of protein complex assembly GO:0043254 3 0.060
ribonucleotide metabolic process GO:0009259 27 0.059
Human
response to stress GO:0006950 263 0.059
cell motility GO:0048870 244 0.057
cellular lipid catabolic process GO:0044242 3 0.056
small molecule catabolic process GO:0044282 3 0.055
cell part morphogenesis GO:0032990 246 0.055
regulation of endothelial cell proliferation GO:0001936 1 0.054
oxidative phosphorylation GO:0006119 1 0.053
transport GO:0006810 220 0.053
heterocycle metabolic process GO:0046483 290 0.051
Human
oxidation reduction process GO:0055114 41 0.047
Human
alpha amino acid metabolic process GO:1901605 3 0.046
negative regulation of catabolic process GO:0009895 3 0.044
lipid metabolic process GO:0006629 52 0.044
cell migration GO:0016477 237 0.043
ion transport GO:0006811 114 0.040
mitochondrion organization GO:0007005 4 0.040
Human
muscle cell differentiation GO:0042692 139 0.040
fatty acid oxidation GO:0019395 1 0.038
oxoacid metabolic process GO:0043436 31 0.037
regulation of protein catabolic process GO:0042176 1 0.036
cellular component assembly GO:0022607 170 0.036
establishment of protein localization to organelle GO:0072594 4 0.035
muscle structure development GO:0061061 196 0.035
organelle organization GO:0006996 227 0.034
Human
purine containing compound metabolic process GO:0072521 29 0.034
Human
actin filament based process GO:0030029 64 0.034
cellular aromatic compound metabolic process GO:0006725 295 0.034
Human
cellular macromolecule metabolic process GO:0044260 391 0.033
cellular protein catabolic process GO:0044257 4 0.032
cellular component morphogenesis GO:0032989 336 0.032
carboxylic acid metabolic process GO:0019752 22 0.032
cellular nitrogen compound metabolic process GO:0034641 290 0.029
Human
organic acid metabolic process GO:0006082 31 0.028
response to corticosteroid GO:0031960 1 0.028
regulation of establishment of protein localization GO:0070201 4 0.027
oocyte anterior posterior axis specification GO:0007314 4 0.026
protein modification process GO:0036211 100 0.026
cytoskeleton organization GO:0007010 96 0.025
system process GO:0003008 185 0.025
single organism transport GO:0044765 206 0.025
response to chemical GO:0042221 320 0.025
reproduction GO:0000003 40 0.024
positive regulation of transport GO:0051050 2 0.023
striated muscle cell differentiation GO:0051146 129 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
response to glucocorticoid GO:0051384 1 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
dicarboxylic acid metabolic process GO:0043648 1 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.023
localization of cell GO:0051674 244 0.023
multi organism process GO:0051704 134 0.023
protein import GO:0017038 3 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
purine nucleoside monophosphate metabolic process GO:0009126 5 0.022
Human
spermatid differentiation GO:0048515 2 0.022
negative regulation of biological process GO:0048519 304 0.022
phosphorus metabolic process GO:0006793 109 0.022
Human
estrogen metabolic process GO:0008210 2 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
digestive tract development GO:0048565 265 0.022
macromolecular complex subunit organization GO:0043933 74 0.022
cytokinesis GO:0000910 3 0.022
gtp metabolic process GO:0046039 4 0.021
nucleotide metabolic process GO:0009117 28 0.021
Human
positive regulation of apoptotic signaling pathway GO:2001235 1 0.021
multicellular organism growth GO:0035264 4 0.021
negative regulation of kinase activity GO:0033673 4 0.021
regulation of protein transport GO:0051223 3 0.021
metal ion transport GO:0030001 58 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
protein complex subunit organization GO:0071822 46 0.020
protein polymerization GO:0051258 4 0.020
cation transport GO:0006812 81 0.020
brain development GO:0007420 293 0.020
regulation of cell communication GO:0010646 232 0.019
protein metabolic process GO:0019538 183 0.019
cellular catabolic process GO:0044248 27 0.019
positive regulation of secretion GO:0051047 1 0.019
cellular response to decreased oxygen levels GO:0036294 1 0.019
cellular carbohydrate metabolic process GO:0044262 4 0.019
regulation of binding GO:0051098 3 0.019
neurotransmitter transport GO:0006836 2 0.019
nitrogen compound metabolic process GO:0006807 319 0.019
Human
organophosphate metabolic process GO:0019637 37 0.018
Human
phosphate containing compound metabolic process GO:0006796 108 0.018
Human
nucleobase containing small molecule metabolic process GO:0055086 32 0.018
Human
positive regulation of stem cell proliferation GO:2000648 1 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
transmembrane transport GO:0055085 120 0.018
single organism localization GO:1902578 225 0.017
cellular macromolecular complex assembly GO:0034622 24 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
behavior GO:0007610 74 0.017
nucleoside metabolic process GO:0009116 11 0.017
Human
gastrulation GO:0007369 208 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
purine ribonucleoside metabolic process GO:0046128 10 0.017
Human
cellular component movement GO:0006928 335 0.017
cellular protein complex assembly GO:0043623 19 0.017
ribose phosphate metabolic process GO:0019693 27 0.017
Human
angiogenesis GO:0001525 158 0.016
striated muscle cell development GO:0055002 108 0.016
regulation of reproductive process GO:2000241 4 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
carbohydrate derivative metabolic process GO:1901135 61 0.016
Human
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
digestive system development GO:0055123 289 0.016
positive regulation of catabolic process GO:0009896 4 0.016
purine ribonucleotide metabolic process GO:0009150 27 0.016
Human
signal transduction GO:0007165 455 0.016
organic substance catabolic process GO:1901575 28 0.016
amine metabolic process GO:0009308 2 0.016
morphogenesis of an epithelium GO:0002009 333 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
membrane invagination GO:0010324 1 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
membrane fusion GO:0061025 2 0.015
regulation of biological quality GO:0065008 263 0.015
Human
guanosine containing compound catabolic process GO:1901069 2 0.015
protein localization to nucleus GO:0034504 3 0.014
coenzyme biosynthetic process GO:0009108 2 0.014
macromolecular complex assembly GO:0065003 35 0.014
response to external stimulus GO:0009605 264 0.014
response to nutrient GO:0007584 3 0.014
regulation of signal transduction GO:0009966 225 0.014
protein homooligomerization GO:0051260 3 0.014
translational initiation GO:0006413 3 0.014
nucleoside phosphate metabolic process GO:0006753 28 0.014
Human
cellular amino acid metabolic process GO:0006520 7 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
neuromuscular synaptic transmission GO:0007274 2 0.014
pole plasm assembly GO:0007315 4 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
gtp catabolic process GO:0006184 2 0.014
regulation of metal ion transport GO:0010959 4 0.014
mesenchymal cell proliferation GO:0010463 1 0.013
spermatid development GO:0007286 2 0.013
primary neural tube formation GO:0014020 1 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
generation of precursor metabolites and energy GO:0006091 5 0.013
Human
response to organic substance GO:0010033 153 0.013
transcription dna templated GO:0006351 181 0.013
protein complex biogenesis GO:0070271 30 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of developmental process GO:0050793 247 0.013
head development GO:0060322 303 0.013
regulation of mitochondrion organization GO:0010821 1 0.013
sensory organ development GO:0007423 393 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
regulation of calcium ion transport GO:0051924 2 0.013
stem cell maintenance GO:0019827 4 0.013
cellular transition metal ion homeostasis GO:0046916 3 0.013
positive regulation of biological process GO:0048518 253 0.013
negative regulation of cellular process GO:0048523 283 0.013
stem cell proliferation GO:0072089 4 0.012
eye development GO:0001654 277 0.012
muscle cell development GO:0055001 115 0.012
cellular protein modification process GO:0006464 100 0.012
phosphorylation GO:0016310 69 0.012
digestive tract morphogenesis GO:0048546 231 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
monocarboxylic acid biosynthetic process GO:0072330 12 0.012
catabolic process GO:0009056 32 0.012
cellular response to hypoxia GO:0071456 1 0.012
negative regulation of reproductive process GO:2000242 3 0.012
single fertilization GO:0007338 3 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
cellular component disassembly GO:0022411 1 0.012
apoptotic process GO:0006915 116 0.012
Human
multi organism reproductive process GO:0044703 36 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
chordate embryonic development GO:0043009 271 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
regulation of gtpase activity GO:0043087 2 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
regulation of cellular component organization GO:0051128 86 0.011
nucleoside monophosphate metabolic process GO:0009123 6 0.011
Human
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
cell death GO:0008219 121 0.011
Human
cellular nitrogen compound catabolic process GO:0044270 15 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 9 0.011
Human
negative regulation of cellular catabolic process GO:0031330 3 0.011
protein modification by small protein removal GO:0070646 1 0.011
regulation of fatty acid metabolic process GO:0019217 1 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
regulation of oocyte development GO:0060281 3 0.011
cellular amino acid biosynthetic process GO:0008652 2 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
cellular amine metabolic process GO:0044106 2 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
striated muscle tissue development GO:0014706 110 0.010
regulation of signaling GO:0023051 235 0.010
macromolecule modification GO:0043412 111 0.010
microtubule based process GO:0007017 60 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010

ndufs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
leigh disease DOID:3652 0 0.160
disease of metabolism DOID:0014667 0 0.160
mitochondrial metabolism disease DOID:700 0 0.160
inherited metabolic disorder DOID:655 0 0.160
cancer DOID:162 0 0.038
disease of cellular proliferation DOID:14566 0 0.038
organ system cancer DOID:0050686 0 0.038
endocrine gland cancer DOID:170 0 0.027
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.018
bone disease DOID:0080001 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016