Danio rerio

0 known processes

sncga

synuclein, gamma a

(Aliases: MGC123342,zgc:123342,im:6900770,zgc:110133)

sncga biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.197
monoamine transport GO:0015844 1 0.133
Mouse
sensory organ development GO:0007423 393 0.105
neuron neuron synaptic transmission GO:0007270 1 0.100
cellular macromolecule metabolic process GO:0044260 391 0.097
nitrogen compound metabolic process GO:0006807 319 0.080
nucleic acid metabolic process GO:0090304 244 0.075
signal transduction GO:0007165 455 0.074
digestive system development GO:0055123 289 0.070
regulation of multicellular organismal process GO:0051239 277 0.070
regulation of macromolecule metabolic process GO:0060255 317 0.066
digestive tract development GO:0048565 265 0.064
cellular aromatic compound metabolic process GO:0006725 295 0.064
nucleobase containing compound metabolic process GO:0006139 274 0.063
regulation of metabolic process GO:0019222 359 0.059
aging GO:0007568 2 0.058
cognition GO:0050890 1 0.058
cell migration GO:0016477 237 0.055
regulation of primary metabolic process GO:0080090 311 0.054
camera type eye development GO:0043010 222 0.052
larval development GO:0002164 2 0.048
transport GO:0006810 220 0.047
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.045
transmembrane transport GO:0055085 120 0.045
eye development GO:0001654 277 0.043
ion transport GO:0006811 114 0.043
Mouse
determination of left right symmetry GO:0007368 179 0.042
behavior GO:0007610 74 0.042
Mouse
adult behavior GO:0030534 2 0.041
Mouse
regulation of gene expression GO:0010468 265 0.040
single organism transport GO:0044765 206 0.040
Mouse
negative regulation of cellular process GO:0048523 283 0.040
regulation of muscle contraction GO:0006937 3 0.039
regulation of biological quality GO:0065008 263 0.039
Mouse
cellular biosynthetic process GO:0044249 286 0.039
positive regulation of transport GO:0051050 2 0.038
regulation of nucleotide catabolic process GO:0030811 2 0.038
embryonic organ morphogenesis GO:0048562 274 0.037
digestive tract morphogenesis GO:0048546 231 0.037
cation transport GO:0006812 81 0.036
Mouse
establishment of localization GO:0051234 244 0.036
Mouse
transcription dna templated GO:0006351 181 0.036
response to chemical GO:0042221 320 0.036
gtp catabolic process GO:0006184 2 0.036
synaptic transmission glycinergic GO:0060012 1 0.035
heart development GO:0007507 313 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
gland development GO:0048732 143 0.035
organelle fusion GO:0048284 3 0.035
heterocycle metabolic process GO:0046483 290 0.035
nucleocytoplasmic transport GO:0006913 4 0.034
i kappab kinase nf kappab signaling GO:0007249 4 0.033
negative regulation of biological process GO:0048519 304 0.033
small molecule metabolic process GO:0044281 77 0.033
negative regulation of signal transduction GO:0009968 94 0.033
liver development GO:0001889 96 0.032
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.032
neuron differentiation GO:0030182 353 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
heterocycle biosynthetic process GO:0018130 215 0.032
guanosine containing compound catabolic process GO:1901069 2 0.032
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
regulation of multicellular organismal development GO:2000026 223 0.031
regulation of rna metabolic process GO:0051252 224 0.031
cell migration involved in gastrulation GO:0042074 79 0.031
cellular component movement GO:0006928 335 0.031
regulation of gtp catabolic process GO:0033124 2 0.030
cell morphogenesis GO:0000902 289 0.030
regulation of signal transduction GO:0009966 225 0.030
ear development GO:0043583 127 0.030
regionalization GO:0003002 274 0.030
cellular nitrogen compound metabolic process GO:0034641 290 0.029
cellular response to nutrient levels GO:0031669 2 0.029
cell surface receptor signaling pathway GO:0007166 325 0.029
regulation of cell differentiation GO:0045595 142 0.029
developmental growth GO:0048589 166 0.029
specification of symmetry GO:0009799 204 0.028
cell part morphogenesis GO:0032990 246 0.028
single organism localization GO:1902578 225 0.028
Mouse
small gtpase mediated signal transduction GO:0007264 8 0.028
regulation of blood vessel size GO:0050880 2 0.028
guanosine containing compound metabolic process GO:1901068 4 0.027
nuclear transport GO:0051169 4 0.027
system process GO:0003008 185 0.027
regulation of tube size GO:0035150 2 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.027
localization of cell GO:0051674 244 0.027
sensory organ morphogenesis GO:0090596 200 0.026
lipid storage GO:0019915 1 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.025
regulation of rho protein signal transduction GO:0035023 2 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
smooth muscle contraction GO:0006939 2 0.025
somite development GO:0061053 96 0.025
protein import into nucleus GO:0006606 3 0.025
regulation of protein transport GO:0051223 3 0.025
gtp metabolic process GO:0046039 4 0.025
calcium ion import GO:0070509 4 0.025
regulation of signaling GO:0023051 235 0.024
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.024
tube morphogenesis GO:0035239 349 0.024
locomotion GO:0040011 313 0.024
regulation of cellular biosynthetic process GO:0031326 245 0.024
response to xenobiotic stimulus GO:0009410 45 0.023
regulation of protein catabolic process GO:0042176 1 0.023
positive regulation of biological process GO:0048518 253 0.023
eye morphogenesis GO:0048592 144 0.023
positive regulation of catabolic process GO:0009896 4 0.023
response to stress GO:0006950 263 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
organic substance biosynthetic process GO:1901576 289 0.023
oxoacid metabolic process GO:0043436 31 0.023
pigmentation GO:0043473 85 0.023
ion transmembrane transport GO:0034220 91 0.023
eye photoreceptor cell differentiation GO:0001754 45 0.023
amine metabolic process GO:0009308 2 0.023
myeloid cell differentiation GO:0030099 86 0.023
stem cell maintenance GO:0019827 4 0.022
somitogenesis GO:0001756 87 0.022
peptidyl serine phosphorylation GO:0018105 1 0.022
immune system development GO:0002520 191 0.022
blood vessel development GO:0001568 246 0.022
peptidyl serine modification GO:0018209 2 0.022
gastrulation GO:0007369 208 0.022
developmental growth involved in morphogenesis GO:0060560 86 0.022
maintenance of location GO:0051235 4 0.022
regulation of cytokine production GO:0001817 3 0.022
gastrulation with mouth forming second GO:0001702 44 0.022
phosphate containing compound metabolic process GO:0006796 108 0.021
retina morphogenesis in camera type eye GO:0060042 79 0.021
response to nutrient GO:0007584 3 0.021
positive regulation of secretion GO:0051047 1 0.021
homeostatic process GO:0042592 142 0.021
protein metabolic process GO:0019538 183 0.021
mitochondrion organization GO:0007005 4 0.021
cell cycle g1 s phase transition GO:0044843 1 0.021
notochord development GO:0030903 54 0.021
embryonic limb morphogenesis GO:0030326 2 0.020
brain development GO:0007420 293 0.020
cell fate commitment GO:0045165 99 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
hemopoiesis GO:0030097 183 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
hepaticobiliary system development GO:0061008 98 0.020
neurological system process GO:0050877 62 0.020
multicellular organism growth GO:0035264 4 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
regulation of neurogenesis GO:0050767 87 0.020
cell motility GO:0048870 244 0.020
chordate embryonic development GO:0043009 271 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
regulation of blood pressure GO:0008217 1 0.019
organic acid metabolic process GO:0006082 31 0.019
rna biosynthetic process GO:0032774 181 0.019
cellular response to external stimulus GO:0071496 2 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
gene expression GO:0010467 252 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
determination of heart left right asymmetry GO:0061371 117 0.019
response to vitamin GO:0033273 3 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
determination of bilateral symmetry GO:0009855 204 0.019
cell projection organization GO:0030030 284 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
cellular component morphogenesis GO:0032989 336 0.018
regulation of cell development GO:0060284 100 0.018
exocytosis GO:0006887 1 0.018
intracellular signal transduction GO:0035556 85 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
membrane hyperpolarization GO:0060081 1 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
regulation of cell morphogenesis GO:0022604 42 0.018
regulation of gtpase activity GO:0043087 2 0.018
axon development GO:0061564 166 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.018
immune system process GO:0002376 241 0.018
regulation of apoptotic process GO:0042981 98 0.017
negative regulation of metabolic process GO:0009892 86 0.017
positive regulation of metabolic process GO:0009893 108 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
regulation of binding GO:0051098 3 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
response to drug GO:0042493 3 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
regulation of synapse organization GO:0050807 3 0.017
regulation of transporter activity GO:0032409 2 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
regulation of molecular function GO:0065009 70 0.017
regulation of rna biosynthetic process GO:2001141 213 0.016
regulation of protein targeting GO:1903533 2 0.016
cellular amine metabolic process GO:0044106 2 0.016
homeostasis of number of cells GO:0048872 62 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
negative regulation of mapk cascade GO:0043409 4 0.016
synaptic vesicle localization GO:0097479 1 0.016
central nervous system development GO:0007417 387 0.016
cation transmembrane transport GO:0098655 65 0.016
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
regulation of neuron differentiation GO:0045664 56 0.016
regulation of cell communication GO:0010646 232 0.016
Mouse
regulation of developmental process GO:0050793 247 0.016
negative regulation of kinase activity GO:0033673 4 0.016
ras protein signal transduction GO:0007265 7 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
sensory system development GO:0048880 76 0.015
fertilization GO:0009566 3 0.015
taxis GO:0042330 109 0.015
chemosensory behavior GO:0007635 1 0.015
regulation of neuron projection development GO:0010975 40 0.015
chemical homeostasis GO:0048878 49 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
neurotransmitter secretion GO:0007269 2 0.015
Mouse
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
inner ear morphogenesis GO:0042472 63 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
regulation of chemotaxis GO:0050920 18 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
regulation of membrane potential GO:0042391 23 0.015
neurotransmitter transport GO:0006836 2 0.015
Mouse
establishment of endothelial barrier GO:0061028 3 0.015
rho protein signal transduction GO:0007266 5 0.015
lateral line development GO:0048882 66 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
locomotory behavior GO:0007626 34 0.015
Mouse
cellular response to chemical stimulus GO:0070887 157 0.015
phagocytosis GO:0006909 3 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
muscle hypertrophy GO:0014896 2 0.014
convergent extension GO:0060026 118 0.014
negative regulation of cell communication GO:0010648 96 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
regulation of inhibitory postsynaptic membrane potential GO:0060080 1 0.014
regulation of locomotion GO:0040012 55 0.014
regulation of transcription dna templated GO:0006355 213 0.014
regulation of system process GO:0044057 40 0.014
organelle localization GO:0051640 49 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
cell growth GO:0016049 57 0.014
positive regulation of rho protein signal transduction GO:0035025 0 0.014
cell projection morphogenesis GO:0048858 244 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
cellular localization GO:0051641 97 0.014
Mouse
dorsal ventral pattern formation GO:0009953 125 0.014
regulation of cell shape GO:0008360 1 0.014
superoxide metabolic process GO:0006801 2 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
hormone secretion GO:0046879 2 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
phagocytosis engulfment GO:0006911 1 0.014
negative regulation of catabolic process GO:0009895 3 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
neural retina development GO:0003407 49 0.014
lateral line system development GO:0048925 76 0.014
regulation of response to stimulus GO:0048583 269 0.014
proteasomal protein catabolic process GO:0010498 2 0.013
positive regulation of blood circulation GO:1903524 2 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
nucleic acid templated transcription GO:0097659 181 0.013
camera type eye morphogenesis GO:0048593 108 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
growth GO:0040007 174 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.013
regulation of programmed cell death GO:0043067 101 0.013
single fertilization GO:0007338 3 0.013
regulation of wound healing GO:0061041 2 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
hatching gland development GO:0048785 3 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
cellular response to oxygen levels GO:0071453 1 0.013
negative regulation of signaling GO:0023057 96 0.013
cell death GO:0008219 121 0.013
connective tissue development GO:0061448 99 0.013
macromolecule localization GO:0033036 54 0.013
Mouse
positive regulation of cell adhesion GO:0045785 1 0.013
nucleobase containing small molecule metabolic process GO:0055086 32 0.013
cellular response to xenobiotic stimulus GO:0071466 35 0.013
response to carbohydrate GO:0009743 3 0.013
cellular component disassembly GO:0022411 1 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
establishment of localization in cell GO:0051649 77 0.013
Mouse
ion homeostasis GO:0050801 41 0.013
head development GO:0060322 303 0.013
regulation of response to external stimulus GO:0032101 31 0.012
regulation of ras gtpase activity GO:0032318 2 0.012
somatic muscle development GO:0007525 4 0.012
germ line stem cell maintenance GO:0030718 2 0.012
germ line stem cell division GO:0042078 1 0.012
appendage morphogenesis GO:0035107 56 0.012
regulation of muscle hypertrophy GO:0014743 2 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
cell projection assembly GO:0030031 64 0.012
erythrocyte homeostasis GO:0034101 55 0.012
positive regulation of cell cycle GO:0045787 3 0.012
regulation of bone remodeling GO:0046850 2 0.012
cellular protein catabolic process GO:0044257 4 0.012
regulation of reproductive process GO:2000241 4 0.012
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.012
regulation of protein binding GO:0043393 3 0.012
protein targeting to nucleus GO:0044744 3 0.012
positive regulation of cytokine production GO:0001819 2 0.012
regulation of cell activation GO:0050865 1 0.012
endocrine process GO:0050886 2 0.012
regulation of dendrite development GO:0050773 3 0.012
positive regulation of immune effector process GO:0002699 3 0.012
small molecule catabolic process GO:0044282 3 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
regulation of calcium ion transport GO:0051924 2 0.012
leukocyte proliferation GO:0070661 1 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
epiboly GO:0090504 41 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.011
single organism metabolic process GO:0044710 217 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
axon ensheathment in central nervous system GO:0032291 2 0.011
cellular protein modification process GO:0006464 100 0.011
primitive erythrocyte differentiation GO:0060319 5 0.011
cell substrate adhesion GO:0031589 4 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
protein secretion GO:0009306 1 0.011
Mouse
cranial nerve development GO:0021545 42 0.011
protein stabilization GO:0050821 2 0.011
response to external stimulus GO:0009605 264 0.011
mitotic recombination GO:0006312 2 0.011
erythrocyte differentiation GO:0030218 54 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.011
regulation of postsynaptic membrane potential GO:0060078 1 0.011
regulation of dna recombination GO:0000018 2 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
stem cell proliferation GO:0072089 4 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.011
negative regulation of defense response GO:0031348 2 0.011
sprouting angiogenesis GO:0002040 53 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
muscle system process GO:0003012 20 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
programmed cell death GO:0012501 119 0.011
response to monosaccharide GO:0034284 3 0.011
heart morphogenesis GO:0003007 156 0.011
regulation of metal ion transport GO:0010959 4 0.011
neuron development GO:0048666 262 0.010
otic vesicle development GO:0071599 42 0.010
positive regulation of cellular component biogenesis GO:0044089 3 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
regulation of biosynthetic process GO:0009889 250 0.010
apoptotic process GO:0006915 116 0.010
b cell activation GO:0042113 2 0.010
response to wounding GO:0009611 116 0.010
wound healing GO:0042060 90 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
alcohol biosynthetic process GO:0046165 2 0.010
divalent inorganic cation homeostasis GO:0072507 22 0.010
glucose homeostasis GO:0042593 1 0.010
positive regulation of ras protein signal transduction GO:0046579 1 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
organelle organization GO:0006996 227 0.010
reactive oxygen species biosynthetic process GO:1903409 1 0.010
protein localization to plasma membrane GO:0072659 1 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
membrane invagination GO:0010324 1 0.010
positive regulation of cellular process GO:0048522 201 0.010

sncga disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
nervous system disease DOID:863 0 0.020
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.013
retinal disease DOID:5679 0 0.010
retinal degeneration DOID:8466 0 0.010