Danio rerio

10 known processes

cx52.6

connexin 52.6

cx52.6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular process GO:0048522 201 0.427
response to stress GO:0006950 263 0.277
Zebrafish
embryonic organ development GO:0048568 381 0.256
Zebrafish
immune system process GO:0002376 241 0.219
Zebrafish
signal transduction GO:0007165 455 0.210
regulation of primary metabolic process GO:0080090 311 0.205
aromatic compound biosynthetic process GO:0019438 217 0.193
response to chemical GO:0042221 320 0.181
cell projection organization GO:0030030 284 0.176
positive regulation of biological process GO:0048518 253 0.174
brain development GO:0007420 293 0.173
skeletal system development GO:0001501 181 0.173
Zebrafish
regulation of metabolic process GO:0019222 359 0.164
response to external stimulus GO:0009605 264 0.162
single organism metabolic process GO:0044710 217 0.158
cognition GO:0050890 1 0.158
retina development in camera type eye GO:0060041 146 0.152
homeostatic process GO:0042592 142 0.149
organic cyclic compound metabolic process GO:1901360 301 0.149
heterocycle metabolic process GO:0046483 290 0.148
cellular macromolecule metabolic process GO:0044260 391 0.148
head development GO:0060322 303 0.143
organic cyclic compound biosynthetic process GO:1901362 223 0.137
negative regulation of biological process GO:0048519 304 0.136
single organism organelle organization GO:1902589 199 0.130
Zebrafish
regulation of response to stimulus GO:0048583 269 0.112
ribonucleotide biosynthetic process GO:0009260 20 0.112
ion transmembrane transport GO:0034220 91 0.111
Zebrafish
camera type eye development GO:0043010 222 0.111
ion transport GO:0006811 114 0.110
Zebrafish
negative regulation of cellular process GO:0048523 283 0.109
cellular biosynthetic process GO:0044249 286 0.106
aging GO:0007568 2 0.105
generation of neurons GO:0048699 385 0.103
biosynthetic process GO:0009058 294 0.100
organic substance biosynthetic process GO:1901576 289 0.100
eye development GO:0001654 277 0.100
regulation of lyase activity GO:0051339 12 0.098
embryo development ending in birth or egg hatching GO:0009792 271 0.097
Zebrafish
gene expression GO:0010467 252 0.097
taxis GO:0042330 109 0.097
cellular aromatic compound metabolic process GO:0006725 295 0.095
neurotransmitter transport GO:0006836 2 0.095
angiogenesis GO:0001525 158 0.092
response to light stimulus GO:0009416 46 0.089
muscle cell differentiation GO:0042692 139 0.088
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.087
locomotion GO:0040011 313 0.086
regulation of cellular metabolic process GO:0031323 320 0.084
blood vessel morphogenesis GO:0048514 216 0.083
sensory organ development GO:0007423 393 0.082
Zebrafish
g protein coupled receptor signaling pathway GO:0007186 74 0.080
rna metabolic process GO:0016070 219 0.079
phosphorus metabolic process GO:0006793 109 0.078
nucleic acid metabolic process GO:0090304 244 0.078
regulation of nitrogen compound metabolic process GO:0051171 251 0.077
regulation of biological quality GO:0065008 263 0.075
establishment of localization in cell GO:0051649 77 0.074
nucleobase containing compound biosynthetic process GO:0034654 205 0.071
sensory organ morphogenesis GO:0090596 200 0.069
regulation of biosynthetic process GO:0009889 250 0.066
transcription dna templated GO:0006351 181 0.065
single organism transport GO:0044765 206 0.064
regulation of gene expression GO:0010468 265 0.063
neuron development GO:0048666 262 0.062
cellular component morphogenesis GO:0032989 336 0.062
Zebrafish
neuron differentiation GO:0030182 353 0.062
cellular macromolecule biosynthetic process GO:0034645 224 0.061
regulation of nucleic acid templated transcription GO:1903506 213 0.061
purine containing compound metabolic process GO:0072521 29 0.059
cellular response to radiation GO:0071478 4 0.059
regulation of cell development GO:0060284 100 0.057
localization of cell GO:0051674 244 0.057
central nervous system development GO:0007417 387 0.057
kupffer s vesicle development GO:0070121 50 0.055
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.054
cellular component movement GO:0006928 335 0.053
death GO:0016265 121 0.052
cell part morphogenesis GO:0032990 246 0.051
nucleobase containing compound metabolic process GO:0006139 274 0.051
phosphate containing compound metabolic process GO:0006796 108 0.050
regulation of rna biosynthetic process GO:2001141 213 0.050
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 5 0.050
cellular protein metabolic process GO:0044267 129 0.049
stem cell proliferation GO:0072089 4 0.049
vasculature development GO:0001944 278 0.047
blood vessel development GO:0001568 246 0.046
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.043
negative regulation of response to stimulus GO:0048585 104 0.042
forebrain development GO:0030900 96 0.041
regulation of transcription dna templated GO:0006355 213 0.040
photoreceptor cell differentiation GO:0046530 55 0.039
transport GO:0006810 220 0.038
eye morphogenesis GO:0048592 144 0.038
cyclic nucleotide metabolic process GO:0009187 18 0.038
rna biosynthetic process GO:0032774 181 0.038
embryonic skeletal joint development GO:0072498 3 0.037
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.037
regulation of signaling GO:0023051 235 0.035
negative regulation of innate immune response GO:0045824 2 0.035
response to uv GO:0009411 3 0.035
heterocycle biosynthetic process GO:0018130 215 0.035
neural crest cell differentiation GO:0014033 72 0.035
macromolecule biosynthetic process GO:0009059 227 0.035
cellular response to unfolded protein GO:0034620 2 0.034
regulation of circadian rhythm GO:0042752 4 0.034
cellular nitrogen compound metabolic process GO:0034641 290 0.033
regulation of localization GO:0032879 104 0.033
Zebrafish
fin development GO:0033333 77 0.033
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.033
maintenance of location GO:0051235 4 0.033
negative regulation of protein kinase activity GO:0006469 4 0.032
chemical homeostasis GO:0048878 49 0.032
response to wounding GO:0009611 116 0.032
Zebrafish
system process GO:0003008 185 0.032
Zebrafish
multicellular organismal response to stress GO:0033555 2 0.031
metal ion homeostasis GO:0055065 26 0.031
locomotor rhythm GO:0045475 3 0.030
wound healing GO:0042060 90 0.030
Zebrafish
nucleoside phosphate metabolic process GO:0006753 28 0.030
purine ribonucleotide biosynthetic process GO:0009152 20 0.030
regulation of cell communication GO:0010646 232 0.030
regulation of transmembrane transport GO:0034762 18 0.030
Zebrafish
embryonic skeletal system development GO:0048706 97 0.029
Zebrafish
nucleobase containing small molecule metabolic process GO:0055086 32 0.029
phototransduction GO:0007602 2 0.029
regulation of multicellular organismal process GO:0051239 277 0.029
positive regulation of transport GO:0051050 2 0.029
regulation of sequestering of calcium ion GO:0051282 4 0.028
regulation of rna metabolic process GO:0051252 224 0.028
negative regulation of signaling GO:0023057 96 0.028
detection of external stimulus GO:0009581 24 0.027
regulation of cyclase activity GO:0031279 12 0.027
lipid storage GO:0019915 1 0.027
organonitrogen compound metabolic process GO:1901564 74 0.027
neuron projection development GO:0031175 180 0.027
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 5 0.027
regulation of molecular function GO:0065009 70 0.027
response to metal ion GO:0010038 34 0.026
epithelial cell differentiation GO:0030855 116 0.026
neural crest cell development GO:0014032 62 0.026
endoplasmic reticulum unfolded protein response GO:0030968 2 0.025
detection of visible light GO:0009584 12 0.025
positive regulation of multicellular organismal process GO:0051240 52 0.025
sensory perception GO:0007600 39 0.025
Zebrafish
larval development GO:0002164 2 0.025
small molecule metabolic process GO:0044281 77 0.024
sequestering of metal ion GO:0051238 3 0.024
response to radiation GO:0009314 51 0.024
transmembrane transport GO:0055085 120 0.024
axonogenesis GO:0007409 152 0.024
cellular component assembly GO:0022607 170 0.024
Zebrafish
embryonic skeletal system morphogenesis GO:0048704 93 0.024
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.023
sequestering of calcium ion GO:0051208 3 0.023
negative regulation of kinase activity GO:0033673 4 0.023
cellular amine metabolic process GO:0044106 2 0.023
positive regulation of somitomeric trunk muscle development GO:0014709 1 0.023
purine nucleotide metabolic process GO:0006163 27 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
cellular localization GO:0051641 97 0.023
nucleic acid templated transcription GO:0097659 181 0.023
response to corticosteroid GO:0031960 1 0.022
fertilization GO:0009566 3 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.022
cell morphogenesis GO:0000902 289 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
ribose phosphate biosynthetic process GO:0046390 20 0.022
response to abiotic stimulus GO:0009628 122 0.022
positive regulation of alcohol biosynthetic process GO:1902932 1 0.022
internal protein amino acid acetylation GO:0006475 2 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
negative regulation of metabolic process GO:0009892 86 0.021
pigmentation GO:0043473 85 0.021
Zebrafish
organophosphate metabolic process GO:0019637 37 0.021
embryonic camera type eye development GO:0031076 29 0.021
organophosphate biosynthetic process GO:0090407 23 0.021
mechanosensory behavior GO:0007638 2 0.021
determination of bilateral symmetry GO:0009855 204 0.021
mesenchymal cell differentiation GO:0048762 87 0.021
photoreceptor cell outer segment organization GO:0035845 9 0.020
hormone secretion GO:0046879 2 0.020
cytoskeleton organization GO:0007010 96 0.020
Zebrafish
carbohydrate derivative metabolic process GO:1901135 61 0.020
neuron projection morphogenesis GO:0048812 161 0.020
detection of light stimulus GO:0009583 12 0.020
sensory perception of chemical stimulus GO:0007606 3 0.020
cation transmembrane transport GO:0098655 65 0.019
cellular ketone metabolic process GO:0042180 11 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
positive regulation of catabolic process GO:0009896 4 0.019
calcium ion dependent exocytosis GO:0017156 1 0.019
er nucleus signaling pathway GO:0006984 2 0.019
mesenchyme development GO:0060485 127 0.019
chordate embryonic development GO:0043009 271 0.019
Zebrafish
response to unfolded protein GO:0006986 2 0.019
cell motility GO:0048870 244 0.019
organelle organization GO:0006996 227 0.019
Zebrafish
intracellular signal transduction GO:0035556 85 0.019
regulation of locomotion GO:0040012 55 0.019
gland development GO:0048732 143 0.019
regulation of signal transduction GO:0009966 225 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
adult behavior GO:0030534 2 0.018
developmental growth GO:0048589 166 0.018
Zebrafish
regulation of phosphorus metabolic process GO:0051174 43 0.018
ribonucleotide metabolic process GO:0009259 27 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.017
cyclic nucleotide biosynthetic process GO:0009190 18 0.017
skeletal muscle tissue development GO:0007519 67 0.017
appendage morphogenesis GO:0035107 56 0.017
Zebrafish
cation homeostasis GO:0055080 33 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
tissue regeneration GO:0042246 74 0.017
Zebrafish
organonitrogen compound biosynthetic process GO:1901566 47 0.017
regulation of nervous system development GO:0051960 90 0.017
protein acylation GO:0043543 3 0.016
regulation of hormone secretion GO:0046883 2 0.016
skeletal system morphogenesis GO:0048705 102 0.016
Zebrafish
protein acetylation GO:0006473 2 0.016
negative regulation of hormone secretion GO:0046888 2 0.016
positive regulation of stem cell proliferation GO:2000648 1 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
negative regulation of mitosis GO:0045839 3 0.016
single organism behavior GO:0044708 24 0.016
hypochord development GO:0055016 3 0.016
regulation of ion transmembrane transport GO:0034765 18 0.016
Zebrafish
endocrine system development GO:0035270 65 0.016
monoamine transport GO:0015844 1 0.016
negative regulation of developmental process GO:0051093 65 0.016
regeneration GO:0031099 91 0.016
Zebrafish
peptide transport GO:0015833 1 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.015
regulation of ion transport GO:0043269 22 0.015
Zebrafish
meiotic nuclear division GO:0007126 4 0.015
chemosensory behavior GO:0007635 1 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
gtp metabolic process GO:0046039 4 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
regulation of cell activation GO:0050865 1 0.015
regulation of circadian sleep wake cycle GO:0042749 1 0.015
regulation of calcium ion dependent exocytosis GO:0017158 1 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
striated muscle cell differentiation GO:0051146 129 0.015
Zebrafish
cellular protein catabolic process GO:0044257 4 0.015
single organism localization GO:1902578 225 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
exocytosis GO:0006887 1 0.015
regulation of receptor activity GO:0010469 2 0.015
regulation of catalytic activity GO:0050790 55 0.014
cellular response to nutrient levels GO:0031669 2 0.014
regulation of neuron differentiation GO:0045664 56 0.014
neurotransmitter secretion GO:0007269 2 0.014
circadian regulation of gene expression GO:0032922 8 0.014
axon development GO:0061564 166 0.014
cell migration GO:0016477 237 0.014
cell cell recognition GO:0009988 1 0.014
establishment of localization GO:0051234 244 0.014
digestive tract development GO:0048565 265 0.014
detection of abiotic stimulus GO:0009582 24 0.014
cell death GO:0008219 121 0.014
ion homeostasis GO:0050801 41 0.014
mitochondrion organization GO:0007005 4 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
stem cell maintenance GO:0019827 4 0.014
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
blood circulation GO:0008015 87 0.014
muscle tissue development GO:0060537 110 0.014
Zebrafish
cyclic purine nucleotide metabolic process GO:0052652 18 0.014
purine containing compound biosynthetic process GO:0072522 20 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.013
negative regulation of signal transduction GO:0009968 94 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
transmission of nerve impulse GO:0019226 19 0.013
regulation of transport GO:0051049 45 0.013
Zebrafish
response to food GO:0032094 1 0.013
macromolecule modification GO:0043412 111 0.013
digestive tract morphogenesis GO:0048546 231 0.013
growth GO:0040007 174 0.013
Zebrafish
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
detection of stimulus GO:0051606 29 0.013
gtp catabolic process GO:0006184 2 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
digestive system development GO:0055123 289 0.013
regulation of transporter activity GO:0032409 2 0.013
regulation of developmental process GO:0050793 247 0.013
stem cell differentiation GO:0048863 117 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.012
behavior GO:0007610 74 0.012
negative regulation of nuclear division GO:0051784 3 0.012
neurological system process GO:0050877 62 0.012
Zebrafish
chemotaxis GO:0006935 104 0.012
muscle cell development GO:0055001 115 0.012
Zebrafish
regulation of cell differentiation GO:0045595 142 0.012
regulation of camp biosynthetic process GO:0030817 9 0.012
alcohol biosynthetic process GO:0046165 2 0.012
organic substance transport GO:0071702 58 0.012
regulation of reproductive process GO:2000241 4 0.012
regulation of protein metabolic process GO:0051246 56 0.012
regulation of transferase activity GO:0051338 16 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
response to organic substance GO:0010033 153 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
diencephalon development GO:0021536 58 0.012
organic acid metabolic process GO:0006082 31 0.012
embryonic eye morphogenesis GO:0048048 30 0.012
locomotory behavior GO:0007626 34 0.012
response to topologically incorrect protein GO:0035966 2 0.012
rhodopsin mediated signaling pathway GO:0016056 1 0.011
establishment of cell polarity GO:0030010 18 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
cell cycle checkpoint GO:0000075 7 0.011
regionalization GO:0003002 274 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
negative regulation of secretion GO:0051048 2 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
negative regulation of defense response GO:0031348 2 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
multicellular organismal signaling GO:0035637 22 0.011
embryonic skeletal joint morphogenesis GO:0060272 3 0.011
Zebrafish
negative regulation of catalytic activity GO:0043086 21 0.011
organelle assembly GO:0070925 110 0.011
Zebrafish
negative regulation of secretion by cell GO:1903531 2 0.011
regulation of response to external stimulus GO:0032101 31 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
negative regulation of feeding behavior GO:2000252 2 0.011
cellular response to light stimulus GO:0071482 4 0.011
regulation of cell death GO:0010941 103 0.011
regulation of cellular component movement GO:0051270 55 0.010
regulation of nucleotide biosynthetic process GO:0030808 15 0.010
positive regulation of nucleic acid templated transcription GO:1903508 57 0.010
myofibril assembly GO:0030239 48 0.010
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.010
mesenchymal cell development GO:0014031 78 0.010
ubiquitin dependent protein catabolic process GO:0006511 3 0.010
skeletal muscle fiber development GO:0048741 35 0.010
negative regulation of cyclase activity GO:0031280 6 0.010
immune response GO:0006955 28 0.010

cx52.6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.053
disease of anatomical entity DOID:7 0 0.024
inherited metabolic disorder DOID:655 0 0.010