Danio rerio

9 known processes

sumo1

SMT3 suppressor of mif two 3 homolog 1 (yeast)

(Aliases: zgc:85634,wu:fd12c02,zgc:65934,wu:fb74c02,hm:zeh0670)

sumo1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell part morphogenesis GO:0032990 246 0.341
positive regulation of cellular process GO:0048522 201 0.320
Human Mouse
protein desumoylation GO:0016926 1 0.313
neuron projection development GO:0031175 180 0.291
cellular respiration GO:0045333 3 0.290
modification dependent macromolecule catabolic process GO:0043632 3 0.264
Human
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.254
cellular component movement GO:0006928 335 0.252
Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.241
regulation of nucleic acid templated transcription GO:1903506 213 0.239
Human Mouse Worm
protein targeting to nucleus GO:0044744 3 0.237
mitotic cell cycle embryonic GO:0045448 2 0.220
cell projection organization GO:0030030 284 0.215
establishment of localization GO:0051234 244 0.209
Mouse
localization of cell GO:0051674 244 0.196
nucleobase containing compound metabolic process GO:0006139 274 0.193
Human Mouse Worm
single organism nuclear import GO:1902593 3 0.189
cell migration GO:0016477 237 0.185
lipid homeostasis GO:0055088 3 0.168
transcription dna templated GO:0006351 181 0.162
Human Mouse Worm
nuclear transport GO:0051169 4 0.153
cellular protein catabolic process GO:0044257 4 0.151
Human
protein localization to nucleus GO:0034504 3 0.151
Mouse
regulation of primary metabolic process GO:0080090 311 0.149
Human Mouse Worm
regulation of cellular metabolic process GO:0031323 320 0.145
Human Mouse Worm
modification dependent protein catabolic process GO:0019941 3 0.144
Human
protein sumoylation GO:0016925 2 0.143
Human Mouse
gene expression GO:0010467 252 0.138
Human Mouse Worm
cell motility GO:0048870 244 0.136
extrinsic apoptotic signaling pathway GO:0097191 3 0.135
protein metabolic process GO:0019538 183 0.130
Human Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.127
Human Mouse Worm
neuron development GO:0048666 262 0.127
positive regulation of biological process GO:0048518 253 0.125
Human Mouse
neuron projection morphogenesis GO:0048812 161 0.124
single organism transport GO:0044765 206 0.122
Mouse
morphogenesis of an epithelium GO:0002009 333 0.122
regulation of signaling GO:0023051 235 0.122
protein import into nucleus GO:0006606 3 0.121
central nervous system neuron differentiation GO:0021953 74 0.119
regulation of metabolic process GO:0019222 359 0.118
Human Mouse Worm
nucleocytoplasmic transport GO:0006913 4 0.113
positive regulation of metabolic process GO:0009893 108 0.111
Human Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.110
central nervous system development GO:0007417 387 0.109
positive regulation of map kinase activity GO:0043406 3 0.105
ubiquitin dependent protein catabolic process GO:0006511 3 0.104
Human
protein import GO:0017038 3 0.097
energy derivation by oxidation of organic compounds GO:0015980 5 0.097
anterior posterior pattern specification GO:0009952 152 0.097
central nervous system neuron axonogenesis GO:0021955 18 0.096
establishment of protein localization to organelle GO:0072594 4 0.096
small gtpase mediated signal transduction GO:0007264 8 0.095
regulation of cellular biosynthetic process GO:0031326 245 0.088
Human Mouse Worm
regulation of cell communication GO:0010646 232 0.087
generation of neurons GO:0048699 385 0.087
cellular macromolecule metabolic process GO:0044260 391 0.086
Human Mouse Worm
nuclear import GO:0051170 3 0.086
cellular response to organic substance GO:0071310 105 0.086
cellular response to chemical stimulus GO:0070887 157 0.085
regionalization GO:0003002 274 0.084
eye development GO:0001654 277 0.083
central nervous system projection neuron axonogenesis GO:0021952 15 0.083
axon development GO:0061564 166 0.082
cell morphogenesis GO:0000902 289 0.080
regulation of protein ubiquitination GO:0031396 3 0.079
cell projection morphogenesis GO:0048858 244 0.079
microtubule based process GO:0007017 60 0.076
mitotic cell cycle GO:0000278 64 0.076
multi organism process GO:0051704 134 0.075
protein polyubiquitination GO:0000209 4 0.075
regulation of cell death GO:0010941 103 0.073
rna metabolic process GO:0016070 219 0.073
Human Mouse Worm
positive regulation of transport GO:0051050 2 0.071
Mouse
ameboidal type cell migration GO:0001667 143 0.070
regulation of rna biosynthetic process GO:2001141 213 0.070
Human Mouse Worm
cell cycle GO:0007049 93 0.069
enzyme linked receptor protein signaling pathway GO:0007167 106 0.067
protein modification process GO:0036211 100 0.066
Human Mouse
sympathetic nervous system development GO:0048485 3 0.066
heart development GO:0007507 313 0.065
cellular aromatic compound metabolic process GO:0006725 295 0.065
Human Mouse Worm
peptide transport GO:0015833 1 0.064
single organism organelle organization GO:1902589 199 0.064
Worm
positive regulation of cellular metabolic process GO:0031325 94 0.063
Human Mouse
regulation of apoptotic process GO:0042981 98 0.061
transport GO:0006810 220 0.061
Mouse
central nervous system neuron development GO:0021954 29 0.061
regulation of biosynthetic process GO:0009889 250 0.061
Human Mouse Worm
organic cyclic compound metabolic process GO:1901360 301 0.060
Human Mouse Worm
regulation of signal transduction GO:0009966 225 0.059
embryonic limb morphogenesis GO:0030326 2 0.058
organelle organization GO:0006996 227 0.057
Mouse Worm
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.056
signal transduction GO:0007165 455 0.056
aging GO:0007568 2 0.055
mitotic dna integrity checkpoint GO:0044774 4 0.055
cellular carbohydrate metabolic process GO:0044262 4 0.054
response to chemical GO:0042221 320 0.054
response to uv GO:0009411 3 0.054
regulation of binding GO:0051098 3 0.054
Human
sensory organ development GO:0007423 393 0.054
death GO:0016265 121 0.054
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.053
Human
regulation of phosphate metabolic process GO:0019220 43 0.053
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.053
Human Mouse Worm
ras protein signal transduction GO:0007265 7 0.052
cellular protein metabolic process GO:0044267 129 0.052
Human Mouse
single organism localization GO:1902578 225 0.052
Mouse
regulation of meiotic cell cycle GO:0051445 1 0.052
positive regulation of cell cycle GO:0045787 3 0.051
embryonic organ development GO:0048568 381 0.051
programmed cell death GO:0012501 119 0.051
stem cell differentiation GO:0048863 117 0.050
cellular macromolecule biosynthetic process GO:0034645 224 0.049
Human Mouse Worm
response to organic substance GO:0010033 153 0.048
positive regulation of signaling GO:0023056 56 0.047
epidermal cell fate specification GO:0009957 4 0.047
nucleobase containing compound biosynthetic process GO:0034654 205 0.047
Human Mouse Worm
mitotic dna damage checkpoint GO:0044773 4 0.046
neural crest cell migration GO:0001755 42 0.046
intracellular signal transduction GO:0035556 85 0.046
neuron differentiation GO:0030182 353 0.045
nitrogen compound metabolic process GO:0006807 319 0.045
Human Mouse Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.045
Human Mouse Worm
positive regulation of protein complex assembly GO:0031334 2 0.045
Human
stem cell development GO:0048864 82 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.044
Human
neural crest cell development GO:0014032 62 0.044
positive regulation of cellular protein metabolic process GO:0032270 22 0.043
Human
cellular protein modification process GO:0006464 100 0.043
Human Mouse
proteasomal protein catabolic process GO:0010498 2 0.043
Human
response to external stimulus GO:0009605 264 0.043
apoptotic process GO:0006915 116 0.042
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.042
Human Worm
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.042
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.041
Human Mouse Worm
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.040
protein modification by small protein removal GO:0070646 1 0.040
embryonic organ morphogenesis GO:0048562 274 0.040
meiotic nuclear division GO:0007126 4 0.040
phagocytosis GO:0006909 3 0.039
response to stress GO:0006950 263 0.039
positive regulation of signal transduction GO:0009967 56 0.038
response to other organism GO:0051707 97 0.038
response to endogenous stimulus GO:0009719 83 0.038
regulation of programmed cell death GO:0043067 101 0.038
cellular localization GO:0051641 97 0.038
Mouse Worm
positive regulation of cellular catabolic process GO:0031331 3 0.037
Human Mouse
mesenchyme development GO:0060485 127 0.037
forebrain cell migration GO:0021885 1 0.037
cellular response to nutrient levels GO:0031669 2 0.036
cell surface receptor signaling pathway GO:0007166 325 0.036
mitotic cell cycle process GO:1903047 48 0.036
gastrulation GO:0007369 208 0.036
positive regulation of ras protein signal transduction GO:0046579 1 0.036
protein acylation GO:0043543 3 0.035
mesenchymal cell development GO:0014031 78 0.034
nucleic acid templated transcription GO:0097659 181 0.034
Human Mouse Worm
positive regulation of cellular biosynthetic process GO:0031328 68 0.034
cell cycle g1 s phase transition GO:0044843 1 0.033
recombinational repair GO:0000725 1 0.033
cellular response to endogenous stimulus GO:0071495 68 0.032
ear development GO:0043583 127 0.032
digestive tract morphogenesis GO:0048546 231 0.032
camera type eye development GO:0043010 222 0.031
heterocycle biosynthetic process GO:0018130 215 0.031
Human Mouse Worm
digestive system development GO:0055123 289 0.031
establishment of localization in cell GO:0051649 77 0.030
chordate embryonic development GO:0043009 271 0.030
negative regulation of cellular process GO:0048523 283 0.030
Human Worm
organic acid metabolic process GO:0006082 31 0.029
macromolecule modification GO:0043412 111 0.029
Human Mouse
regulation of response to stimulus GO:0048583 269 0.029
nucleic acid metabolic process GO:0090304 244 0.028
Human Mouse Worm
macromolecular complex subunit organization GO:0043933 74 0.028
Human
positive regulation of secretion GO:0051047 1 0.027
positive regulation of cell death GO:0010942 29 0.027
embryo development ending in birth or egg hatching GO:0009792 271 0.027
Worm
regulation of gene expression GO:0010468 265 0.027
Human Mouse Worm
negative regulation of programmed cell death GO:0043069 58 0.027
head development GO:0060322 303 0.027
skeletal muscle organ development GO:0060538 78 0.026
locomotion GO:0040011 313 0.026
cellular response to stress GO:0033554 62 0.026
regulation of cell differentiation GO:0045595 142 0.026
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.026
heart morphogenesis GO:0003007 156 0.026
carboxylic acid metabolic process GO:0019752 22 0.025
regulation of cell proliferation GO:0042127 37 0.025
retina development in camera type eye GO:0060041 146 0.025
cellular nitrogen compound metabolic process GO:0034641 290 0.025
Human Mouse Worm
oxidation reduction process GO:0055114 41 0.025
cytokinetic process GO:0032506 2 0.025
regulation of cellular protein catabolic process GO:1903362 1 0.025
Human
larval development GO:0002164 2 0.025
Worm
striated muscle tissue development GO:0014706 110 0.025
transcription from rna polymerase ii promoter GO:0006366 80 0.025
Worm
double strand break repair via homologous recombination GO:0000724 1 0.025
muscle tissue development GO:0060537 110 0.024
vascular endothelial growth factor signaling pathway GO:0038084 3 0.024
post embryonic morphogenesis GO:0009886 4 0.024
cellular component biogenesis GO:0044085 178 0.023
Human
apoptotic signaling pathway GO:0097190 23 0.023
cytokinesis GO:0000910 3 0.022
cellular response to external stimulus GO:0071496 2 0.022
biosynthetic process GO:0009058 294 0.022
Human Mouse Worm
regulation of carbohydrate metabolic process GO:0006109 4 0.022
regulation of reproductive process GO:2000241 4 0.021
midbrain development GO:0030901 28 0.021
cellular component morphogenesis GO:0032989 336 0.021
vesicle mediated transport GO:0016192 22 0.021
axonogenesis GO:0007409 152 0.021
regulation of wound healing GO:0061041 2 0.021
somatic muscle development GO:0007525 4 0.020
positive regulation of apoptotic signaling pathway GO:2001235 1 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
chemotaxis GO:0006935 104 0.020
positive regulation of protein metabolic process GO:0051247 23 0.019
Human
chromatin modification GO:0016568 21 0.019
cell cycle process GO:0022402 53 0.019
regulation of localization GO:0032879 104 0.019
Mouse
glucose homeostasis GO:0042593 1 0.019
pancreas development GO:0031016 84 0.019
nuclear division GO:0000280 23 0.019
lipid storage GO:0019915 1 0.018
neural crest cell differentiation GO:0014033 72 0.018
growth GO:0040007 174 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
Human Mouse Worm
oxoacid metabolic process GO:0043436 31 0.018
ribosomal small subunit biogenesis GO:0042274 2 0.018
brain development GO:0007420 293 0.017
negative regulation of cell death GO:0060548 60 0.017
ribosome biogenesis GO:0042254 9 0.017
chromosome organization GO:0051276 31 0.017
Worm
maintenance of location GO:0051235 4 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
Human Mouse Worm
single organism metabolic process GO:0044710 217 0.017
Mouse
response to growth factor GO:0070848 39 0.017
negative regulation of catabolic process GO:0009895 3 0.017
neurotransmitter secretion GO:0007269 2 0.017
regulation of multicellular organismal development GO:2000026 223 0.016
Worm
neuron migration GO:0001764 22 0.016
adult behavior GO:0030534 2 0.016
negative regulation of biosynthetic process GO:0009890 55 0.016
Human Worm
cilium assembly GO:0042384 58 0.016
regulation of transcription dna templated GO:0006355 213 0.016
Human Mouse Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.016
Human Mouse Worm
positive regulation of catabolic process GO:0009896 4 0.016
Human Mouse
positive regulation of multi organism process GO:0043902 3 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
sensory neuron axon guidance GO:0097374 3 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
Mouse Worm
translational initiation GO:0006413 3 0.015
response to radiation GO:0009314 51 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
sympathetic ganglion development GO:0061549 2 0.015
muscle organ development GO:0007517 101 0.015
positive regulation of myeloid cell differentiation GO:0045639 2 0.015
brain morphogenesis GO:0048854 18 0.015
generation of precursor metabolites and energy GO:0006091 5 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.015
cellular response to starvation GO:0009267 1 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
meiotic cell cycle process GO:1903046 3 0.014
regulation of molecular function GO:0065009 70 0.014
Human Mouse
convergent extension GO:0060026 118 0.014
positive regulation of cell communication GO:0010647 56 0.014
cellular response to growth factor stimulus GO:0071363 39 0.014
epidermis morphogenesis GO:0048730 4 0.014
camera type eye morphogenesis GO:0048593 108 0.014
regulation of protein modification process GO:0031399 29 0.014
sequestering of metal ion GO:0051238 3 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
appendage morphogenesis GO:0035107 56 0.014
regulation of protein catabolic process GO:0042176 1 0.014
Human
digestive tract development GO:0048565 265 0.013
mitotic cytokinesis GO:0000281 3 0.013
post embryonic organ development GO:0048569 4 0.013
Worm
sensory system development GO:0048880 76 0.013
eye morphogenesis GO:0048592 144 0.013
single organism membrane fusion GO:0044801 2 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
cellular protein localization GO:0034613 20 0.013
Mouse Worm
histone modification GO:0016570 20 0.013
amine metabolic process GO:0009308 2 0.013
regulation of axonogenesis GO:0050770 32 0.013
protein acetylation GO:0006473 2 0.012
positive regulation of molecular function GO:0044093 33 0.012
Mouse
cellular response to light stimulus GO:0071482 4 0.012
regulation of hormone secretion GO:0046883 2 0.012
cell death GO:0008219 121 0.012
regeneration GO:0031099 91 0.012
carbohydrate homeostasis GO:0033500 1 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
Human Mouse Worm
reproduction GO:0000003 40 0.012
Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of cell cycle GO:0051726 52 0.012
regulation of neurogenesis GO:0050767 87 0.012
mitotic spindle organization GO:0007052 5 0.012
mitotic g2 dna damage checkpoint GO:0007095 3 0.012
cilium morphogenesis GO:0060271 85 0.012
cellular biosynthetic process GO:0044249 286 0.012
Human Mouse Worm
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
regulation of nervous system development GO:0051960 90 0.012
regulation of chromosome segregation GO:0051983 1 0.012
regulation of developmental process GO:0050793 247 0.011
Worm
organic substance transport GO:0071702 58 0.011
regulation of autophagy GO:0010506 3 0.011
multicellular organism reproduction GO:0032504 35 0.011
positive regulation of wound healing GO:0090303 1 0.011
endocrine hormone secretion GO:0060986 2 0.011
protein dephosphorylation GO:0006470 3 0.011
immune system development GO:0002520 191 0.011
dna biosynthetic process GO:0071897 3 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.011
neural tube patterning GO:0021532 33 0.011
protein k48 linked ubiquitination GO:0070936 1 0.011
myotube differentiation GO:0014902 45 0.011
negative regulation of histone modification GO:0031057 1 0.011
urogenital system development GO:0001655 97 0.011
proteolysis GO:0006508 38 0.011
Human
regulation of cell activation GO:0050865 1 0.011
regulation of embryonic development GO:0045995 47 0.011
cranial ganglion development GO:0061550 3 0.011
stem cell maintenance GO:0019827 4 0.011
cellular response to radiation GO:0071478 4 0.010
hormone transport GO:0009914 2 0.010
defense response GO:0006952 47 0.010
microtubule cytoskeleton organization GO:0000226 33 0.010
fatty acid transport GO:0015908 1 0.010
positive regulation of apoptotic process GO:0043065 29 0.010
protein modification by small protein conjugation or removal GO:0070647 14 0.010
Human Mouse
acylglycerol homeostasis GO:0055090 2 0.010
regulation of dendrite development GO:0050773 3 0.010
regulation of postsynaptic membrane potential GO:0060078 1 0.010
response to light stimulus GO:0009416 46 0.010
muscle structure development GO:0061061 196 0.010
cellular macromolecule localization GO:0070727 21 0.010
Mouse Worm
peripheral nervous system development GO:0007422 55 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.010
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.010
Human Mouse Worm

sumo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.011