Danio rerio

0 known processes

pkm2b

pyruvate kinase, muscle, b

(Aliases: zgc:92037)

pkm2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.128
regulation of cellular metabolic process GO:0031323 320 0.061
aging GO:0007568 2 0.059
cellular nitrogen compound biosynthetic process GO:0044271 218 0.057
Rat
regulation of metabolic process GO:0019222 359 0.057
heterocycle biosynthetic process GO:0018130 215 0.056
Rat
maintenance of location GO:0051235 4 0.055
cellular macromolecule metabolic process GO:0044260 391 0.055
regulation of biological quality GO:0065008 263 0.055
regulation of response to stimulus GO:0048583 269 0.052
regulation of multicellular organismal process GO:0051239 277 0.051
response to chemical GO:0042221 320 0.049
Rat
cellular nitrogen compound metabolic process GO:0034641 290 0.045
Rat
nucleobase containing compound metabolic process GO:0006139 274 0.045
Rat
organic cyclic compound metabolic process GO:1901360 301 0.044
Rat
signal transduction GO:0007165 455 0.043
multicellular organism growth GO:0035264 4 0.043
generation of neurons GO:0048699 385 0.042
regulation of gene expression GO:0010468 265 0.041
neuron neuron synaptic transmission GO:0007270 1 0.040
embryonic organ development GO:0048568 381 0.040
response to drug GO:0042493 3 0.039
positive regulation of transport GO:0051050 2 0.038
regulation of developmental process GO:0050793 247 0.038
cell surface receptor signaling pathway GO:0007166 325 0.037
nitrogen compound metabolic process GO:0006807 319 0.037
Rat
gene expression GO:0010467 252 0.037
regulation of macromolecule metabolic process GO:0060255 317 0.037
cell part morphogenesis GO:0032990 246 0.037
positive regulation of cell cycle GO:0045787 3 0.036
biosynthetic process GO:0009058 294 0.036
Rat
organic cyclic compound biosynthetic process GO:1901362 223 0.036
Rat
locomotion GO:0040011 313 0.035
single organism localization GO:1902578 225 0.035
phagocytosis GO:0006909 3 0.035
regulation of protein transport GO:0051223 3 0.035
heterocycle metabolic process GO:0046483 290 0.035
Rat
regulation of multicellular organismal development GO:2000026 223 0.034
homeostatic process GO:0042592 142 0.034
cellular biosynthetic process GO:0044249 286 0.034
Rat
regulation of multicellular organism growth GO:0040014 4 0.033
organic substance biosynthetic process GO:1901576 289 0.033
Rat
immune system process GO:0002376 241 0.033
cognition GO:0050890 1 0.032
negative regulation of biological process GO:0048519 304 0.032
sensory organ development GO:0007423 393 0.032
regulation of primary metabolic process GO:0080090 311 0.032
transport GO:0006810 220 0.032
embryonic organ morphogenesis GO:0048562 274 0.031
negative regulation of cellular process GO:0048523 283 0.031
cellular response to external stimulus GO:0071496 2 0.031
response to stress GO:0006950 263 0.031
Rat
regulation of nitrogen compound metabolic process GO:0051171 251 0.030
nucleic acid metabolic process GO:0090304 244 0.030
regulation of cell communication GO:0010646 232 0.030
lipid storage GO:0019915 1 0.030
nuclear transport GO:0051169 4 0.030
cellular protein catabolic process GO:0044257 4 0.029
adult behavior GO:0030534 2 0.029
system process GO:0003008 185 0.029
response to carbohydrate GO:0009743 3 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.028
heart development GO:0007507 313 0.028
cell substrate adhesion GO:0031589 4 0.028
response to external stimulus GO:0009605 264 0.027
Rat
nucleobase containing compound biosynthetic process GO:0034654 205 0.027
Rat
neuron differentiation GO:0030182 353 0.027
cell projection morphogenesis GO:0048858 244 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
cellular amine metabolic process GO:0044106 2 0.026
single organism transport GO:0044765 206 0.026
cellular response to nutrient levels GO:0031669 2 0.026
positive regulation of cellular process GO:0048522 201 0.026
positive regulation of biological process GO:0048518 253 0.025
cellular component morphogenesis GO:0032989 336 0.025
regulation of biosynthetic process GO:0009889 250 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
mitochondrion organization GO:0007005 4 0.025
regulation of synaptic plasticity GO:0048167 1 0.025
embryo development ending in birth or egg hatching GO:0009792 271 0.025
regulation of signaling GO:0023051 235 0.025
cell projection organization GO:0030030 284 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
protein metabolic process GO:0019538 183 0.024
cytokinesis GO:0000910 3 0.024
establishment of localization GO:0051234 244 0.024
regulation of mrna processing GO:0050684 3 0.024
regulation of signal transduction GO:0009966 225 0.024
regulation of cytoplasmic transport GO:1903649 4 0.023
regulation of intracellular protein transport GO:0033157 3 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
regulation of dendrite development GO:0050773 3 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.023
cellular component biogenesis GO:0044085 178 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
Rat
macromolecule biosynthetic process GO:0009059 227 0.023
positive regulation of catabolic process GO:0009896 4 0.023
tube morphogenesis GO:0035239 349 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
regulation of protein complex assembly GO:0043254 3 0.023
cellular response to chemical stimulus GO:0070887 157 0.023
regulation of metal ion transport GO:0010959 4 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
organelle organization GO:0006996 227 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
autophagy GO:0006914 4 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
synaptic transmission cholinergic GO:0007271 4 0.022
protein polymerization GO:0051258 4 0.022
cellular protein metabolic process GO:0044267 129 0.022
neuron development GO:0048666 262 0.021
localization of cell GO:0051674 244 0.021
regulation of cell death GO:0010941 103 0.021
cell motility GO:0048870 244 0.021
amine metabolic process GO:0009308 2 0.021
response to organic substance GO:0010033 153 0.021
Rat
blood circulation GO:0008015 87 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
Yeast Rat
axonogenesis GO:0007409 152 0.021
regulation of tube size GO:0035150 2 0.021
muscle structure development GO:0061061 196 0.021
striated muscle tissue development GO:0014706 110 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
sequestering of metal ion GO:0051238 3 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
organic acid metabolic process GO:0006082 31 0.021
Yeast Rat
phosphate containing compound metabolic process GO:0006796 108 0.020
Yeast Rat
directional locomotion GO:0033058 1 0.020
camera type eye development GO:0043010 222 0.020
gtp metabolic process GO:0046039 4 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
sequestering of calcium ion GO:0051208 3 0.020
regulation of muscle contraction GO:0006937 3 0.020
blood vessel development GO:0001568 246 0.020
developmental growth GO:0048589 166 0.020
Rat
regulation of synapse organization GO:0050807 3 0.020
cellular ketone metabolic process GO:0042180 11 0.020
i kappab kinase nf kappab signaling GO:0007249 4 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
small molecule metabolic process GO:0044281 77 0.020
Yeast Rat
cellular component movement GO:0006928 335 0.020
transcription dna templated GO:0006351 181 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
rna metabolic process GO:0016070 219 0.020
synaptic vesicle transport GO:0048489 1 0.020
ion transport GO:0006811 114 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
protein localization to nucleus GO:0034504 3 0.020
regulation of cell development GO:0060284 100 0.020
growth GO:0040007 174 0.020
Rat
cell migration GO:0016477 237 0.020
sensory organ morphogenesis GO:0090596 200 0.019
cell morphogenesis GO:0000902 289 0.019
neurotransmitter secretion GO:0007269 2 0.019
muscle organ development GO:0007517 101 0.019
protein targeting to nucleus GO:0044744 3 0.019
digestive tract development GO:0048565 265 0.019
nucleic acid templated transcription GO:0097659 181 0.019
neuron projection development GO:0031175 180 0.019
regulation of sequestering of calcium ion GO:0051282 4 0.019
regulation of binding GO:0051098 3 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
neurotransmitter transport GO:0006836 2 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
Rat
rna biosynthetic process GO:0032774 181 0.019
exocytosis GO:0006887 1 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
single organism nuclear import GO:1902593 3 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
death GO:0016265 121 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
regulation of cytokine production GO:0001817 3 0.018
oxoacid metabolic process GO:0043436 31 0.018
Yeast Rat
blood vessel morphogenesis GO:0048514 216 0.018
cell death GO:0008219 121 0.018
neuron projection morphogenesis GO:0048812 161 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
response to monosaccharide GO:0034284 3 0.018
circulatory system process GO:0003013 87 0.018
regulation of reproductive process GO:2000241 4 0.018
single organism metabolic process GO:0044710 217 0.018
Yeast Rat
digestive tract morphogenesis GO:0048546 231 0.018
nuclear import GO:0051170 3 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
digestive system development GO:0055123 289 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
stem cell proliferation GO:0072089 4 0.017
cellular component assembly GO:0022607 170 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
negative regulation of kinase activity GO:0033673 4 0.017
gtp catabolic process GO:0006184 2 0.017
protein acylation GO:0043543 3 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
protein import GO:0017038 3 0.017
protein import into nucleus GO:0006606 3 0.017
regulation of cell substrate adhesion GO:0010810 1 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
muscle cell development GO:0055001 115 0.017
programmed cell death GO:0012501 119 0.017
regulation of protein catabolic process GO:0042176 1 0.017
regulation of autophagy GO:0010506 3 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
response to endogenous stimulus GO:0009719 83 0.017
Rat
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
multi organism process GO:0051704 134 0.017
apoptotic process GO:0006915 116 0.017
regulation of cell activation GO:0050865 1 0.017
response to hexose GO:0009746 3 0.017
vasculature development GO:0001944 278 0.017
regulation of apoptotic process GO:0042981 98 0.016
regulation of cell shape GO:0008360 1 0.016
regulation of dendrite morphogenesis GO:0048814 3 0.016
connective tissue development GO:0061448 99 0.016
angiogenesis GO:0001525 158 0.016
phosphorus metabolic process GO:0006793 109 0.016
Yeast Rat
regulation of protein targeting GO:1903533 2 0.016
secondary metabolic process GO:0019748 3 0.016
central nervous system development GO:0007417 387 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
regulation of blood vessel size GO:0050880 2 0.016
regulation of rna metabolic process GO:0051252 224 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
retina development in camera type eye GO:0060041 146 0.016
tissue remodeling GO:0048771 4 0.016
behavior GO:0007610 74 0.016
single organism organelle organization GO:1902589 199 0.016
meiotic cell cycle process GO:1903046 3 0.016
ion transmembrane transport GO:0034220 91 0.016
axon development GO:0061564 166 0.016
peptide metabolic process GO:0006518 1 0.016
protein localization to plasma membrane GO:0072659 1 0.016
heart contraction GO:0060047 71 0.015
organelle fusion GO:0048284 3 0.015
carbohydrate homeostasis GO:0033500 1 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
synaptic vesicle localization GO:0097479 1 0.015
striated muscle cell development GO:0055002 108 0.015
wound healing GO:0042060 90 0.015
Rat
regulation of programmed cell death GO:0043067 101 0.015
meiotic nuclear division GO:0007126 4 0.015
determination of left right symmetry GO:0007368 179 0.015
gastrulation GO:0007369 208 0.015
peptide transport GO:0015833 1 0.015
rna localization GO:0006403 4 0.015
regionalization GO:0003002 274 0.015
gland development GO:0048732 143 0.015
Rat
eye development GO:0001654 277 0.015
superoxide metabolic process GO:0006801 2 0.015
muscle cell differentiation GO:0042692 139 0.015
protein acetylation GO:0006473 2 0.015
cellular response to organic substance GO:0071310 105 0.014
determination of bilateral symmetry GO:0009855 204 0.014
mitochondrial transport GO:0006839 2 0.014
regulation of skeletal muscle tissue development GO:0048641 4 0.014
muscle tissue development GO:0060537 110 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
cellular response to oxygen levels GO:0071453 1 0.014
response to corticosteroid GO:0031960 1 0.014
chordate embryonic development GO:0043009 271 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
adherens junction organization GO:0034332 4 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
cellular response to starvation GO:0009267 1 0.014
nuclear export GO:0051168 1 0.014
heart process GO:0003015 71 0.014
specification of symmetry GO:0009799 204 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
regulation of calcium ion transport GO:0051924 2 0.014
organelle assembly GO:0070925 110 0.014
regulation of cell differentiation GO:0045595 142 0.014
b cell activation GO:0042113 2 0.014
peptidyl serine modification GO:0018209 2 0.014
cellular localization GO:0051641 97 0.014
positive regulation of blood circulation GO:1903524 2 0.014
protein dephosphorylation GO:0006470 3 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
negative regulation of catabolic process GO:0009895 3 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
cellular protein modification process GO:0006464 100 0.014
cell matrix adhesion GO:0007160 4 0.014
glucose homeostasis GO:0042593 1 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
membrane fusion GO:0061025 2 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
regulation of neurogenesis GO:0050767 87 0.013
head development GO:0060322 303 0.013
hepaticobiliary system development GO:0061008 98 0.013
Rat
organonitrogen compound metabolic process GO:1901564 74 0.013
Rat
response to glucocorticoid GO:0051384 1 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
regulation of neuron differentiation GO:0045664 56 0.013
regulation of blood pressure GO:0008217 1 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
response to glucose GO:0009749 3 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
regulation of localization GO:0032879 104 0.013
stem cell maintenance GO:0019827 4 0.013
cartilage development GO:0051216 96 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
macromolecule modification GO:0043412 111 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
phagocytosis engulfment GO:0006911 1 0.013
neuroblast proliferation GO:0007405 2 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
skeletal muscle tissue development GO:0007519 67 0.013
cellular component disassembly GO:0022411 1 0.013
response to alkaloid GO:0043279 2 0.013
cytoskeleton organization GO:0007010 96 0.013
positive regulation of cytokine production GO:0001819 2 0.013
negative regulation of defense response GO:0031348 2 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
response to amino acid GO:0043200 2 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
sensory system development GO:0048880 76 0.012
regulation of transcription dna templated GO:0006355 213 0.012
negative regulation of signaling GO:0023057 96 0.012
intracellular signal transduction GO:0035556 85 0.012
ear development GO:0043583 127 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
striated muscle cell differentiation GO:0051146 129 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
lateral line system development GO:0048925 76 0.012
regulation of synapse assembly GO:0051963 3 0.012
response to wounding GO:0009611 116 0.012
Rat
dna templated transcription elongation GO:0006354 3 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
cellular amide metabolic process GO:0043603 4 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
antimicrobial humoral response GO:0019730 2 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
regulation of cellular component organization GO:0051128 86 0.012
response to external biotic stimulus GO:0043207 97 0.012
cation homeostasis GO:0055080 33 0.012
regulation of inflammatory response GO:0050727 2 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
cell cycle arrest GO:0007050 1 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
negative regulation of metabolic process GO:0009892 86 0.012
response to hydrogen peroxide GO:0042542 3 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
actin filament based movement GO:0030048 1 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
regulation of jak stat cascade GO:0046425 3 0.012
response to other organism GO:0051707 97 0.012
response to uv GO:0009411 3 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
fin morphogenesis GO:0033334 53 0.012
transmembrane transport GO:0055085 120 0.012
skeletal system development GO:0001501 181 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
ventricular cardiac muscle tissue development GO:0003229 3 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
regulation of protein polymerization GO:0032271 2 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
spermatid development GO:0007286 2 0.011
membrane invagination GO:0010324 1 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
female sex differentiation GO:0046660 4 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
protein modification process GO:0036211 100 0.011
g protein coupled receptor signaling pathway GO:0007186 74 0.011
negative regulation of cell death GO:0060548 60 0.011
chemosensory behavior GO:0007635 1 0.011
chemical homeostasis GO:0048878 49 0.011
regulation of nervous system development GO:0051960 90 0.011
ion homeostasis GO:0050801 41 0.011
negative regulation of cytokine production GO:0001818 1 0.011
macromolecular complex disassembly GO:0032984 1 0.011
mesenchyme development GO:0060485 127 0.011
reactive oxygen species metabolic process GO:0072593 6 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
regulation of protein binding GO:0043393 3 0.011
cilium morphogenesis GO:0060271 85 0.011
positive regulation of cell activation GO:0050867 1 0.011
leukocyte proliferation GO:0070661 1 0.011
post embryonic morphogenesis GO:0009886 4 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
protein secretion GO:0009306 1 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
ameboidal type cell migration GO:0001667 143 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
protein complex disassembly GO:0043241 1 0.011
stem cell division GO:0017145 1 0.011
fin development GO:0033333 77 0.011
protein stabilization GO:0050821 2 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
tissue regeneration GO:0042246 74 0.011
Rat
regulation of myotube differentiation GO:0010830 2 0.011
negative regulation of cell communication GO:0010648 96 0.011
nuclear migration GO:0007097 3 0.011
positive regulation of secretion GO:0051047 1 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
hemopoiesis GO:0030097 183 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
female gonad development GO:0008585 4 0.010
cellular response to hypoxia GO:0071456 1 0.010
taxis GO:0042330 109 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
positive regulation of jnk cascade GO:0046330 3 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
notochord development GO:0030903 54 0.010
small molecule catabolic process GO:0044282 3 0.010

pkm2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.105
nervous system disease DOID:863 0 0.023
musculoskeletal system disease DOID:17 0 0.021
immune system disease DOID:2914 0 0.017
muscular disease DOID:0080000 0 0.015
muscle tissue disease DOID:66 0 0.015
disease of metabolism DOID:0014667 0 0.014
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
cardiovascular system disease DOID:1287 0 0.010