Danio rerio

0 known processes

nsmce4a

non-SMC element 4 homolog A (S. cerevisiae)

(Aliases: zgc:109897,MGC109897)

nsmce4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.097
regulation of multicellular organism growth GO:0040014 4 0.081
multicellular organism growth GO:0035264 4 0.057
aging GO:0007568 2 0.057
nitrogen compound metabolic process GO:0006807 319 0.054
negative regulation of biological process GO:0048519 304 0.053
cellular biosynthetic process GO:0044249 286 0.050
stem cell proliferation GO:0072089 4 0.050
regulation of metabolic process GO:0019222 359 0.047
regulation of cellular metabolic process GO:0031323 320 0.044
aromatic compound biosynthetic process GO:0019438 217 0.043
protein acetylation GO:0006473 2 0.043
cellular aromatic compound metabolic process GO:0006725 295 0.043
negative regulation of cellular process GO:0048523 283 0.042
organic cyclic compound metabolic process GO:1901360 301 0.042
vasculature development GO:0001944 278 0.041
heterocycle metabolic process GO:0046483 290 0.041
leukocyte proliferation GO:0070661 1 0.040
establishment of protein localization to organelle GO:0072594 4 0.040
signal transduction GO:0007165 455 0.040
brain development GO:0007420 293 0.039
organic substance biosynthetic process GO:1901576 289 0.039
cell surface receptor signaling pathway GO:0007166 325 0.039
morphogenesis of an epithelium GO:0002009 333 0.038
cellular nitrogen compound biosynthetic process GO:0044271 218 0.037
biosynthetic process GO:0009058 294 0.036
gene expression GO:0010467 252 0.036
maintenance of location GO:0051235 4 0.035
cellular macromolecule metabolic process GO:0044260 391 0.035
nucleocytoplasmic transport GO:0006913 4 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.034
nuclear transport GO:0051169 4 0.034
central nervous system development GO:0007417 387 0.033
lipid storage GO:0019915 1 0.033
heart development GO:0007507 313 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.032
regulation of primary metabolic process GO:0080090 311 0.032
regulation of multicellular organismal process GO:0051239 277 0.032
tissue remodeling GO:0048771 4 0.032
meiotic nuclear division GO:0007126 4 0.032
protein acylation GO:0043543 3 0.032
protein metabolic process GO:0019538 183 0.031
response to stress GO:0006950 263 0.031
Human
specification of symmetry GO:0009799 204 0.031
regulation of macromolecule metabolic process GO:0060255 317 0.031
establishment of localization GO:0051234 244 0.031
heterocycle biosynthetic process GO:0018130 215 0.030
regulation of cytokine production GO:0001817 3 0.030
head development GO:0060322 303 0.030
cellular respiration GO:0045333 3 0.030
determination of bilateral symmetry GO:0009855 204 0.030
immune system process GO:0002376 241 0.030
chordate embryonic development GO:0043009 271 0.029
embryo development ending in birth or egg hatching GO:0009792 271 0.029
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.029
regulation of biosynthetic process GO:0009889 250 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
nucleic acid metabolic process GO:0090304 244 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.029
regulation of cytoplasmic transport GO:1903649 4 0.029
cellular component movement GO:0006928 335 0.028
regulation of cellular biosynthetic process GO:0031326 245 0.028
regulation of stem cell proliferation GO:0072091 2 0.028
response to chemical GO:0042221 320 0.027
regulation of developmental process GO:0050793 247 0.027
cell part morphogenesis GO:0032990 246 0.027
mononuclear cell proliferation GO:0032943 1 0.027
embryonic organ development GO:0048568 381 0.027
organic acid catabolic process GO:0016054 3 0.027
determination of left right symmetry GO:0007368 179 0.027
positive regulation of transport GO:0051050 2 0.027
regulation of intracellular protein transport GO:0033157 3 0.027
skeletal system development GO:0001501 181 0.027
single organism nuclear import GO:1902593 3 0.026
digestive tract development GO:0048565 265 0.026
localization of cell GO:0051674 244 0.025
macromolecule biosynthetic process GO:0009059 227 0.025
small molecule catabolic process GO:0044282 3 0.025
tube morphogenesis GO:0035239 349 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
regulation of rna biosynthetic process GO:2001141 213 0.024
rna biosynthetic process GO:0032774 181 0.024
regulation of dna replication GO:0006275 3 0.024
regulation of gene expression GO:0010468 265 0.024
b cell activation GO:0042113 2 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.023
negative regulation of sequestering of calcium ion GO:0051283 4 0.023
sensory organ development GO:0007423 393 0.023
lymphocyte proliferation GO:0046651 1 0.023
response to drug GO:0042493 3 0.023
protein import GO:0017038 3 0.023
neurotransmitter transport GO:0006836 2 0.023
embryonic organ morphogenesis GO:0048562 274 0.023
blood vessel development GO:0001568 246 0.022
regulation of protein transport GO:0051223 3 0.022
nucleic acid templated transcription GO:0097659 181 0.022
organelle organization GO:0006996 227 0.022
regulation of cell activation GO:0050865 1 0.022
sensory organ morphogenesis GO:0090596 200 0.022
regulation of neural precursor cell proliferation GO:2000177 3 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
organic acid metabolic process GO:0006082 31 0.022
positive regulation of biological process GO:0048518 253 0.022
Human
regionalization GO:0003002 274 0.022
neuron differentiation GO:0030182 353 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
protein localization to nucleus GO:0034504 3 0.021
mitochondrion organization GO:0007005 4 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
phagocytosis GO:0006909 3 0.021
sequestering of calcium ion GO:0051208 3 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
protein import into nucleus GO:0006606 3 0.021
lipid catabolic process GO:0016042 4 0.021
locomotion GO:0040011 313 0.021
eye morphogenesis GO:0048592 144 0.020
regulation of rna metabolic process GO:0051252 224 0.020
digestive system development GO:0055123 289 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
rna metabolic process GO:0016070 219 0.020
single organism localization GO:1902578 225 0.020
cell projection morphogenesis GO:0048858 244 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
regulation of protein localization to nucleus GO:1900180 2 0.020
positive regulation of catabolic process GO:0009896 4 0.020
amine metabolic process GO:0009308 2 0.020
protein targeting to nucleus GO:0044744 3 0.019
cellular response to nutrient levels GO:0031669 2 0.019
regulation of cell differentiation GO:0045595 142 0.019
carboxylic acid catabolic process GO:0046395 3 0.019
cellular protein catabolic process GO:0044257 4 0.019
cell substrate adhesion GO:0031589 4 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
blood vessel morphogenesis GO:0048514 216 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
single organism organelle organization GO:1902589 199 0.019
growth GO:0040007 174 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
stem cell maintenance GO:0019827 4 0.019
single organism metabolic process GO:0044710 217 0.019
positive regulation of cytokine production GO:0001819 2 0.019
positive regulation of cellular process GO:0048522 201 0.018
Human
carboxylic acid metabolic process GO:0019752 22 0.018
cellular response to external stimulus GO:0071496 2 0.018
regulation of cell communication GO:0010646 232 0.018
anterior posterior pattern specification GO:0009952 152 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
regulation of sequestering of calcium ion GO:0051282 4 0.018
regulation of protein complex assembly GO:0043254 3 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
ear development GO:0043583 127 0.018
oxoacid metabolic process GO:0043436 31 0.018
meiotic cell cycle process GO:1903046 3 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
cellular amine metabolic process GO:0044106 2 0.018
nuclear export GO:0051168 1 0.018
regulation of binding GO:0051098 3 0.018
cellular component disassembly GO:0022411 1 0.018
regulation of protein catabolic process GO:0042176 1 0.018
regulation of neurotransmitter transport GO:0051588 1 0.018
oxidative phosphorylation GO:0006119 1 0.018
lateral inhibition GO:0046331 1 0.018
sequestering of metal ion GO:0051238 3 0.018
regulation of signaling GO:0023051 235 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
camera type eye development GO:0043010 222 0.018
proteasomal protein catabolic process GO:0010498 2 0.017
cell projection organization GO:0030030 284 0.017
cellular component morphogenesis GO:0032989 336 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
regulation of response to stimulus GO:0048583 269 0.017
Human
neuron projection development GO:0031175 180 0.017
regulation of protein targeting GO:1903533 2 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
negative regulation of gene expression GO:0010629 65 0.017
eye development GO:0001654 277 0.017
developmental growth GO:0048589 166 0.017
regulation of signal transduction GO:0009966 225 0.017
nuclear import GO:0051170 3 0.017
neurotransmitter secretion GO:0007269 2 0.017
regulation of mrna processing GO:0050684 3 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
negative regulation of kinase activity GO:0033673 4 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
muscle structure development GO:0061061 196 0.017
cell migration GO:0016477 237 0.016
peptidyl serine modification GO:0018209 2 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
positive regulation of cell activation GO:0050867 1 0.016
cognition GO:0050890 1 0.016
regulation of cell shape GO:0008360 1 0.016
cell morphogenesis GO:0000902 289 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
embryonic heart tube development GO:0035050 133 0.016
regulation of stem cell differentiation GO:2000736 4 0.016
embryonic skeletal system development GO:0048706 97 0.016
single organism transport GO:0044765 206 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
regulation of transmembrane transporter activity GO:0022898 2 0.016
regulation of inflammatory response GO:0050727 2 0.016
transmembrane transport GO:0055085 120 0.016
negative regulation of metabolic process GO:0009892 86 0.016
positive regulation of cell cycle GO:0045787 3 0.016
positive regulation of translation GO:0045727 1 0.016
renal tubule morphogenesis GO:0061333 1 0.015
cell motility GO:0048870 244 0.015
transport GO:0006810 220 0.015
regulation of neurotransmitter secretion GO:0046928 1 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
neuroblast proliferation GO:0007405 2 0.015
transcription dna templated GO:0006351 181 0.015
rna localization GO:0006403 4 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
regulation of biological quality GO:0065008 263 0.015
negative regulation of neural precursor cell proliferation GO:2000178 1 0.015
double strand break repair GO:0006302 3 0.015
protein dephosphorylation GO:0006470 3 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
hemopoiesis GO:0030097 183 0.015
skeletal system morphogenesis GO:0048705 102 0.014
inner ear development GO:0048839 126 0.014
cytosolic calcium ion transport GO:0060401 3 0.014
mitochondrial transport GO:0006839 2 0.014
regulation of transcription dna templated GO:0006355 213 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
calcium ion transport into cytosol GO:0060402 3 0.014
regulation of metal ion transport GO:0010959 4 0.014
response to external stimulus GO:0009605 264 0.014
response to organic substance GO:0010033 153 0.014
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.014
regulation of response to biotic stimulus GO:0002831 2 0.014
cellular response to organic substance GO:0071310 105 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
cellular response to oxygen levels GO:0071453 1 0.014
neuron development GO:0048666 262 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
negative regulation of defense response GO:0031348 2 0.014
intra s dna damage checkpoint GO:0031573 1 0.014
angiogenesis GO:0001525 158 0.014
macromolecular complex disassembly GO:0032984 1 0.014
camera type eye morphogenesis GO:0048593 108 0.014
immune system development GO:0002520 191 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
protein stabilization GO:0050821 2 0.014
generation of neurons GO:0048699 385 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
negative regulation of catabolic process GO:0009895 3 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
gtp catabolic process GO:0006184 2 0.014
urogenital system development GO:0001655 97 0.014
retina development in camera type eye GO:0060041 146 0.014
regulation of myotube differentiation GO:0010830 2 0.014
muscle cell migration GO:0014812 4 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
cellular response to starvation GO:0009267 1 0.013
homeostatic process GO:0042592 142 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
regulation of cell death GO:0010941 103 0.013
cellular protein metabolic process GO:0044267 129 0.013
regulation of protein binding GO:0043393 3 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
cellular component assembly GO:0022607 170 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
system process GO:0003008 185 0.013
regulation of reproductive process GO:2000241 4 0.013
rna export from nucleus GO:0006405 1 0.013
positive regulation of immune effector process GO:0002699 3 0.013
regulation of calcium ion transport GO:0051924 2 0.013
axon development GO:0061564 166 0.013
dna templated transcription elongation GO:0006354 3 0.013
negative regulation of cytokine production GO:0001818 1 0.013
response to uv GO:0009411 3 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
regulation of synapse assembly GO:0051963 3 0.013
sister chromatid cohesion GO:0007062 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
compound eye development GO:0048749 2 0.013
muscle tissue development GO:0060537 110 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
negative regulation of signaling GO:0023057 96 0.013
heart looping GO:0001947 94 0.013
nucleobase containing compound transport GO:0015931 2 0.013
positive regulation of protein complex assembly GO:0031334 2 0.012
negative regulation of multicellular organismal process GO:0051241 69 0.012
cell matrix adhesion GO:0007160 4 0.012
alpha amino acid metabolic process GO:1901605 3 0.012
chemosensory behavior GO:0007635 1 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of synapse organization GO:0050807 3 0.012
female sex differentiation GO:0046660 4 0.012
cellular lipid catabolic process GO:0044242 3 0.012
multi organism process GO:0051704 134 0.012
gastrulation GO:0007369 208 0.012
germ line stem cell maintenance GO:0030718 2 0.012
appendage development GO:0048736 80 0.012
response to wounding GO:0009611 116 0.012
single fertilization GO:0007338 3 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
digestive tract morphogenesis GO:0048546 231 0.012
protein localization to plasma membrane GO:0072659 1 0.012
protein polymerization GO:0051258 4 0.012
post embryonic organ development GO:0048569 4 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
cellular ketone metabolic process GO:0042180 11 0.012
organelle fusion GO:0048284 3 0.012
small molecule metabolic process GO:0044281 77 0.012
response to hexose GO:0009746 3 0.012
multicellular organismal signaling GO:0035637 22 0.012
embryonic skeletal system morphogenesis GO:0048704 93 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
response to alkaloid GO:0043279 2 0.012
multi organism cellular process GO:0044764 2 0.012
regulation of rho protein signal transduction GO:0035023 2 0.012
protein complex disassembly GO:0043241 1 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
positive regulation of endothelial cell migration GO:0010595 2 0.012
mesenchyme development GO:0060485 127 0.012
positive regulation of striated muscle tissue development GO:0045844 1 0.012
regulation of blood vessel size GO:0050880 2 0.012
segmentation GO:0035282 97 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
calcium mediated signaling GO:0019722 2 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
death GO:0016265 121 0.012
synaptic transmission cholinergic GO:0007271 4 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
membrane fusion GO:0061025 2 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
cellular response to light stimulus GO:0071482 4 0.011
membrane invagination GO:0010324 1 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
axonogenesis GO:0007409 152 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
Human
pectoral fin development GO:0033339 50 0.011
positive regulation of secretion GO:0051047 1 0.011
adherens junction organization GO:0034332 4 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
macromolecule modification GO:0043412 111 0.011
gtp metabolic process GO:0046039 4 0.011
pigmentation GO:0043473 85 0.011
protein modification process GO:0036211 100 0.011
alcohol biosynthetic process GO:0046165 2 0.011
response to nutrient GO:0007584 3 0.011
mesenchymal cell proliferation GO:0010463 1 0.011
cellular protein modification process GO:0006464 100 0.011
response to corticosteroid GO:0031960 1 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
stem cell division GO:0017145 1 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
positive regulation of cell substrate adhesion GO:0010811 1 0.011
regulation of tube size GO:0035150 2 0.011
antimicrobial humoral response GO:0019730 2 0.011
nephron epithelium morphogenesis GO:0072088 1 0.011
single organism membrane fusion GO:0044801 2 0.011
peptide transport GO:0015833 1 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
rhombomere 5 development GO:0021571 4 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
bone remodeling GO:0046849 2 0.011
negative regulation of signal transduction GO:0009968 94 0.011
regulation of blood pressure GO:0008217 1 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
heart morphogenesis GO:0003007 156 0.011
response to external biotic stimulus GO:0043207 97 0.011
phagocytosis engulfment GO:0006911 1 0.010
regulation of apoptotic process GO:0042981 98 0.010
cell aging GO:0007569 2 0.010
wound healing GO:0042060 90 0.010
regulation of programmed cell death GO:0043067 101 0.010
nephron morphogenesis GO:0072028 2 0.010
regulation of cell development GO:0060284 100 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
muscle organ development GO:0007517 101 0.010
zymogen activation GO:0031638 3 0.010
regeneration GO:0031099 91 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
negative regulation of multi organism process GO:0043901 3 0.010
response to carbohydrate GO:0009743 3 0.010
regulation of transporter activity GO:0032409 2 0.010
regulation of organelle assembly GO:1902115 4 0.010
b cell mediated immunity GO:0019724 3 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
pancreas development GO:0031016 84 0.010
rna transport GO:0050658 2 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
meiosis i GO:0007127 1 0.010
response to amino acid GO:0043200 2 0.010
interspecies interaction between organisms GO:0044419 4 0.010
nephron tubule morphogenesis GO:0072078 1 0.010

nsmce4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024
nervous system disease DOID:863 0 0.017
immune system disease DOID:2914 0 0.014
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011
sensory system disease DOID:0050155 0 0.011