Danio rerio

24 known processes

pknox1.1

pbx/knotted 1 homeobox 1.1

(Aliases: fc13f10,MGC66244,wu:fc13f10,prep1.1,prep1)

pknox1.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular process GO:0048523 283 0.188
larval development GO:0002164 2 0.164
regulation of multicellular organism growth GO:0040014 4 0.116
cell surface receptor signaling pathway GO:0007166 325 0.112
negative regulation of biological process GO:0048519 304 0.106
intrinsic apoptotic signaling pathway GO:0097193 20 0.098
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.093
cellular protein catabolic process GO:0044257 4 0.093
muscle cell development GO:0055001 115 0.091
response to stress GO:0006950 263 0.084
adult behavior GO:0030534 2 0.072
signal transduction GO:0007165 455 0.071
programmed cell death GO:0012501 119 0.071
multi organism process GO:0051704 134 0.070
extrinsic apoptotic signaling pathway GO:0097191 3 0.066
muscle fiber development GO:0048747 52 0.064
mitotic g2 m transition checkpoint GO:0044818 3 0.061
proteasomal protein catabolic process GO:0010498 2 0.056
regulation of phosphorus metabolic process GO:0051174 43 0.056
striated muscle cell differentiation GO:0051146 129 0.054
mitotic dna integrity checkpoint GO:0044774 4 0.053
regulation of macromolecule metabolic process GO:0060255 317 0.051
maintenance of location GO:0051235 4 0.051
regulation of response to stimulus GO:0048583 269 0.047
mitotic g2 dna damage checkpoint GO:0007095 3 0.046
blood circulation GO:0008015 87 0.045
mitotic cell cycle embryonic GO:0045448 2 0.044
regulation of nitrogen compound metabolic process GO:0051171 251 0.044
aging GO:0007568 2 0.044
heterocycle biosynthetic process GO:0018130 215 0.044
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.043
lipid storage GO:0019915 1 0.039
apoptotic signaling pathway GO:0097190 23 0.038
regulation of signal transduction GO:0009966 225 0.038
regulation of cellular metabolic process GO:0031323 320 0.037
g2 dna damage checkpoint GO:0031572 3 0.037
single organism organelle organization GO:1902589 199 0.036
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.035
chordate embryonic development GO:0043009 271 0.034
central nervous system development GO:0007417 387 0.034
digestive system development GO:0055123 289 0.034
cell migration GO:0016477 237 0.034
gastrulation GO:0007369 208 0.033
brain development GO:0007420 293 0.032
cellular macromolecule metabolic process GO:0044260 391 0.032
single organism metabolic process GO:0044710 217 0.032
regulation of cell communication GO:0010646 232 0.032
carbohydrate derivative biosynthetic process GO:1901137 43 0.031
organic acid metabolic process GO:0006082 31 0.030
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.029
organelle organization GO:0006996 227 0.028
ubiquitin dependent protein catabolic process GO:0006511 3 0.028
intracellular signal transduction GO:0035556 85 0.027
meiotic nuclear division GO:0007126 4 0.027
response to chemical GO:0042221 320 0.027
cellular component movement GO:0006928 335 0.026
transcription from rna polymerase ii promoter GO:0006366 80 0.026
positive regulation of biological process GO:0048518 253 0.026
membrane invagination GO:0010324 1 0.025
cell death GO:0008219 121 0.025
response to abiotic stimulus GO:0009628 122 0.025
regulation of cell shape GO:0008360 1 0.025
organic cyclic compound biosynthetic process GO:1901362 223 0.025
generation of neurons GO:0048699 385 0.025
regulation of rna biosynthetic process GO:2001141 213 0.024
heart contraction GO:0060047 71 0.024
organic substance biosynthetic process GO:1901576 289 0.024
meiotic cell cycle process GO:1903046 3 0.024
phosphorus metabolic process GO:0006793 109 0.023
nuclear import GO:0051170 3 0.023
cell cycle GO:0007049 93 0.022
hatching GO:0035188 4 0.022
protein stabilization GO:0050821 2 0.022
multicellular organismal reproductive process GO:0048609 35 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
digestive tract morphogenesis GO:0048546 231 0.022
establishment of localization GO:0051234 244 0.022
regulation of biological quality GO:0065008 263 0.021
compound eye development GO:0048749 2 0.021
multicellular organism growth GO:0035264 4 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
regionalization GO:0003002 274 0.020
heart process GO:0003015 71 0.020
neurological system process GO:0050877 62 0.020
phagocytosis GO:0006909 3 0.019
regulation of protein transport GO:0051223 3 0.019
regulation of synapse organization GO:0050807 3 0.019
regulation of cellular component organization GO:0051128 86 0.019
pronuclear migration GO:0035046 1 0.019
regulation of cell death GO:0010941 103 0.019
cell motility GO:0048870 244 0.018
digestive tract development GO:0048565 265 0.018
striated muscle cell development GO:0055002 108 0.018
circulatory system process GO:0003013 87 0.018
single organism transport GO:0044765 206 0.017
negative regulation of programmed cell death GO:0043069 58 0.017
regulation of primary metabolic process GO:0080090 311 0.017
regulation of metabolic process GO:0019222 359 0.017
regulation of signaling GO:0023051 235 0.017
regulation of gene expression GO:0010468 265 0.017
transcription dna templated GO:0006351 181 0.017
cellular component disassembly GO:0022411 1 0.017
biosynthetic process GO:0009058 294 0.017
rna metabolic process GO:0016070 219 0.017
internal protein amino acid acetylation GO:0006475 2 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
response to other organism GO:0051707 97 0.016
anterior posterior pattern specification GO:0009952 152 0.016
cell maturation GO:0048469 23 0.016
regulation of organelle assembly GO:1902115 4 0.016
organism emergence from protective structure GO:0071684 4 0.016
heart development GO:0007507 313 0.015
neuron remodeling GO:0016322 1 0.015
response to uv GO:0009411 3 0.015
cellular biosynthetic process GO:0044249 286 0.015
small molecule metabolic process GO:0044281 77 0.015
mitotic cell cycle GO:0000278 64 0.015
centrosome organization GO:0051297 1 0.015
single organism biosynthetic process GO:0044711 71 0.014
regulation of developmental process GO:0050793 247 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
b cell activation GO:0042113 2 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
regulation of protein catabolic process GO:0042176 1 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
mitotic dna damage checkpoint GO:0044773 4 0.014
nitrogen compound metabolic process GO:0006807 319 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
positive regulation of catabolic process GO:0009896 4 0.014
chromosome organization GO:0051276 31 0.014
developmental programmed cell death GO:0010623 4 0.013
mitotic cell cycle process GO:1903047 48 0.013
single organism localization GO:1902578 225 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
neuron differentiation GO:0030182 353 0.013
nuclear transport GO:0051169 4 0.013
protein import into nucleus GO:0006606 3 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
cell death in response to oxidative stress GO:0036473 2 0.013
muscle organ development GO:0007517 101 0.012
regulation of organelle organization GO:0033043 29 0.012
mitochondrion organization GO:0007005 4 0.012
cell proliferation GO:0008283 80 0.012
microtubule organizing center organization GO:0031023 1 0.012
regulation of programmed cell death GO:0043067 101 0.012
small molecule catabolic process GO:0044282 3 0.012
gene expression GO:0010467 252 0.012
ras protein signal transduction GO:0007265 7 0.012
regulation of transcription dna templated GO:0006355 213 0.012
macromolecule modification GO:0043412 111 0.012
lateral inhibition GO:0046331 1 0.012
nucleic acid metabolic process GO:0090304 244 0.012
protein metabolic process GO:0019538 183 0.012
regulation of membrane potential GO:0042391 23 0.012
phagocytosis engulfment GO:0006911 1 0.011
muscle structure development GO:0061061 196 0.011
skeletal muscle fiber development GO:0048741 35 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
tube morphogenesis GO:0035239 349 0.011
response to bacterium GO:0009617 58 0.011
multi organism reproductive process GO:0044703 36 0.011
g protein coupled receptor signaling pathway GO:0007186 74 0.011
cellular response to stress GO:0033554 62 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
nucleic acid templated transcription GO:0097659 181 0.011
wnt signaling pathway GO:0016055 80 0.011
protein homooligomerization GO:0051260 3 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
actin cytoskeleton organization GO:0030036 63 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
negative regulation of metabolic process GO:0009892 86 0.010
protein targeting to nucleus GO:0044744 3 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
negative regulation of protein kinase activity GO:0006469 4 0.010
glucose import GO:0046323 2 0.010
asymmetric protein localization GO:0008105 6 0.010
oxoacid metabolic process GO:0043436 31 0.010
protein polyubiquitination GO:0000209 4 0.010

pknox1.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
nervous system disease DOID:863 0 0.014
immune system disease DOID:2914 0 0.010