Danio rerio

26 known processes

pknox1.2

pbx/knotted 1 homeobox 1.2

(Aliases: knotted,pbx,prep1.2)

pknox1.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
taxis GO:0042330 109 0.693
locomotion GO:0040011 313 0.574
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.564
larval development GO:0002164 2 0.527
cellular component morphogenesis GO:0032989 336 0.522
chemotaxis GO:0006935 104 0.520
cellular macromolecule metabolic process GO:0044260 391 0.500
Zebrafish Mouse
organic cyclic compound metabolic process GO:1901360 301 0.497
Zebrafish Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.462
Zebrafish Mouse
central nervous system development GO:0007417 387 0.445
Zebrafish
eye development GO:0001654 277 0.419
Zebrafish Mouse
neuron projection morphogenesis GO:0048812 161 0.416
multicellular organism growth GO:0035264 4 0.414
response to stress GO:0006950 263 0.411
Zebrafish
cell migration GO:0016477 237 0.405
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.398
Zebrafish Mouse
regulation of multicellular organism growth GO:0040014 4 0.382
regulation of synapse organization GO:0050807 3 0.375
negative regulation of biological process GO:0048519 304 0.365
response to organic substance GO:0010033 153 0.362
Zebrafish
embryonic organ development GO:0048568 381 0.345
Zebrafish
positive regulation of biological process GO:0048518 253 0.344
Zebrafish Mouse
head development GO:0060322 303 0.331
Zebrafish
negative regulation of cellular process GO:0048523 283 0.325
response to chemical GO:0042221 320 0.318
Zebrafish
stem cell proliferation GO:0072089 4 0.317
Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.308
Zebrafish Mouse
inner ear development GO:0048839 126 0.307
neuron differentiation GO:0030182 353 0.304
axon guidance GO:0007411 86 0.294
neuron development GO:0048666 262 0.291
regulation of nitrogen compound metabolic process GO:0051171 251 0.290
Zebrafish Mouse
cell projection organization GO:0030030 284 0.286
regulation of signal transduction GO:0009966 225 0.286
Zebrafish
generation of neurons GO:0048699 385 0.281
axon development GO:0061564 166 0.275
response to external stimulus GO:0009605 264 0.271
regulation of multicellular organismal process GO:0051239 277 0.269
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.265
Zebrafish Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.262
Zebrafish Mouse
cellular biosynthetic process GO:0044249 286 0.260
Zebrafish Mouse
gene expression GO:0010467 252 0.247
Zebrafish Mouse
cell projection morphogenesis GO:0048858 244 0.243
growth GO:0040007 174 0.242
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.240
Zebrafish Mouse
signal transduction GO:0007165 455 0.234
single organism organelle organization GO:1902589 199 0.232
positive regulation of cellular biosynthetic process GO:0031328 68 0.229
Zebrafish Mouse
negative regulation of response to stimulus GO:0048585 104 0.227
embryonic organ morphogenesis GO:0048562 274 0.225
Zebrafish
regulation of response to stimulus GO:0048583 269 0.224
Zebrafish
establishment of localization GO:0051234 244 0.220
cellular component biogenesis GO:0044085 178 0.217
cell part morphogenesis GO:0032990 246 0.214
regulation of nervous system development GO:0051960 90 0.213
cellular nitrogen compound metabolic process GO:0034641 290 0.212
Zebrafish Mouse
morphogenesis of an epithelium GO:0002009 333 0.200
Zebrafish
regulation of cell differentiation GO:0045595 142 0.194
regulation of axonogenesis GO:0050770 32 0.194
biosynthetic process GO:0009058 294 0.193
Zebrafish Mouse
cellular component movement GO:0006928 335 0.189
Zebrafish
regulation of response to stress GO:0080134 36 0.186
nucleic acid metabolic process GO:0090304 244 0.186
Zebrafish Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.182
regulation of macromolecule metabolic process GO:0060255 317 0.182
Zebrafish Mouse
axonogenesis GO:0007409 152 0.180
response to wounding GO:0009611 116 0.179
Zebrafish
muscle structure development GO:0061061 196 0.176
regulation of dna replication GO:0006275 3 0.173
regulation of nucleic acid templated transcription GO:1903506 213 0.171
Zebrafish Mouse
response to biotic stimulus GO:0009607 97 0.170
homeostatic process GO:0042592 142 0.168
Zebrafish Mouse
regulation of primary metabolic process GO:0080090 311 0.167
Zebrafish Mouse
cell motility GO:0048870 244 0.167
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.163
Zebrafish Mouse
negative regulation of cell communication GO:0010648 96 0.157
phosphate containing compound metabolic process GO:0006796 108 0.154
brain development GO:0007420 293 0.154
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.154
Zebrafish Mouse
chromosome organization GO:0051276 31 0.152
ear development GO:0043583 127 0.149
immune effector process GO:0002252 23 0.145
regulation of biosynthetic process GO:0009889 250 0.145
Zebrafish Mouse
positive regulation of transport GO:0051050 2 0.144
peptidyl serine phosphorylation GO:0018105 1 0.141
neuron projection development GO:0031175 180 0.140
system process GO:0003008 185 0.139
positive regulation of macromolecule metabolic process GO:0010604 93 0.139
Zebrafish Mouse
neurological system process GO:0050877 62 0.138
cellular component assembly GO:0022607 170 0.138
regulation of neurogenesis GO:0050767 87 0.138
regulation of developmental process GO:0050793 247 0.137
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.136
multi organism process GO:0051704 134 0.134
organophosphate metabolic process GO:0019637 37 0.134
apoptotic process GO:0006915 116 0.132
developmental growth GO:0048589 166 0.131
Zebrafish
cell cycle process GO:0022402 53 0.131
Zebrafish
regulation of response to external stimulus GO:0032101 31 0.130
regulation of cell size GO:0008361 29 0.123
hindbrain development GO:0030902 91 0.123
Zebrafish
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.119
tube morphogenesis GO:0035239 349 0.118
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.117
Zebrafish Mouse
dendrite development GO:0016358 9 0.117
regulation of wound healing GO:0061041 2 0.117
regulation of multicellular organismal development GO:2000026 223 0.116
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.113
Zebrafish Mouse
heterocycle biosynthetic process GO:0018130 215 0.110
Zebrafish Mouse
cell morphogenesis GO:0000902 289 0.110
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.109
behavior GO:0007610 74 0.109
positive regulation of cellular process GO:0048522 201 0.109
Zebrafish Mouse
localization of cell GO:0051674 244 0.108
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.107
Zebrafish Mouse
aromatic compound biosynthetic process GO:0019438 217 0.107
Zebrafish Mouse
regulation of postsynaptic membrane potential GO:0060078 1 0.102
cognition GO:0050890 1 0.101
transport GO:0006810 220 0.101
response to bacterium GO:0009617 58 0.101
single organism transport GO:0044765 206 0.100
regulation of cell morphogenesis GO:0022604 42 0.100
regulation of metabolic process GO:0019222 359 0.099
Zebrafish Mouse
immune response GO:0006955 28 0.098
regulation of biological quality GO:0065008 263 0.098
Zebrafish Mouse
exocytosis GO:0006887 1 0.098
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.096
Zebrafish Mouse
cell cycle GO:0007049 93 0.096
Zebrafish
phagocytosis GO:0006909 3 0.094
convergent extension GO:0060026 118 0.093
cellular response to chemical stimulus GO:0070887 157 0.091
Zebrafish
ion transmembrane transport GO:0034220 91 0.091
membrane fusion GO:0061025 2 0.089
neuromuscular synaptic transmission GO:0007274 2 0.088
cytokinesis GO:0000910 3 0.086
neuron projection guidance GO:0097485 86 0.086
purine containing compound metabolic process GO:0072521 29 0.086
intracellular signal transduction GO:0035556 85 0.085
immune system process GO:0002376 241 0.084
Zebrafish Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.083
Zebrafish Mouse
organelle organization GO:0006996 227 0.082
negative regulation of signaling GO:0023057 96 0.081
negative regulation of signal transduction GO:0009968 94 0.081
stem cell maintenance GO:0019827 4 0.081
regulation of synapse assembly GO:0051963 3 0.080
positive regulation of catabolic process GO:0009896 4 0.080
actin filament polymerization GO:0030041 2 0.080
female sex differentiation GO:0046660 4 0.080
response to alkaloid GO:0043279 2 0.079
synapse organization GO:0050808 21 0.079
regulation of cell cycle GO:0051726 52 0.079
organic cyclic compound biosynthetic process GO:1901362 223 0.079
Zebrafish Mouse
cellular protein metabolic process GO:0044267 129 0.079
meiotic nuclear division GO:0007126 4 0.078
cell proliferation GO:0008283 80 0.074
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.074
Zebrafish Mouse
convergent extension involved in gastrulation GO:0060027 71 0.074
negative regulation of gene expression GO:0010629 65 0.073
mitotic cell cycle process GO:1903047 48 0.071
Zebrafish
regulation of anatomical structure size GO:0090066 33 0.069
macromolecule modification GO:0043412 111 0.069
cell death GO:0008219 121 0.069
heterocycle metabolic process GO:0046483 290 0.068
Zebrafish Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.068
Zebrafish
protein targeting to nucleus GO:0044744 3 0.068
positive regulation of metabolic process GO:0009893 108 0.067
Zebrafish Mouse
positive regulation of rna metabolic process GO:0051254 59 0.067
Zebrafish Mouse
establishment of protein localization to organelle GO:0072594 4 0.067
myotube differentiation GO:0014902 45 0.067
heart morphogenesis GO:0003007 156 0.067
Zebrafish
spermatid development GO:0007286 2 0.066
maintenance of location GO:0051235 4 0.066
regulation of cellular component organization GO:0051128 86 0.066
epithelial tube morphogenesis GO:0060562 148 0.065
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.065
Zebrafish Mouse
regulation of cell shape GO:0008360 1 0.065
peptidyl serine modification GO:0018209 2 0.065
negative regulation of developmental process GO:0051093 65 0.064
positive regulation of cellular component movement GO:0051272 11 0.064
regulation of cell communication GO:0010646 232 0.064
Zebrafish
negative regulation of protein kinase b signaling GO:0051898 2 0.064
digestive system development GO:0055123 289 0.064
Zebrafish
defense response GO:0006952 47 0.064
cellular nitrogen compound biosynthetic process GO:0044271 218 0.063
Zebrafish Mouse
regulation of signaling GO:0023051 235 0.063
Zebrafish
multicellular organism reproduction GO:0032504 35 0.063
protein metabolic process GO:0019538 183 0.062
regulation of protein polymerization GO:0032271 2 0.062
guanosine containing compound catabolic process GO:1901069 2 0.061
somatic muscle development GO:0007525 4 0.061
regulation of metal ion transport GO:0010959 4 0.061
ear morphogenesis GO:0042471 64 0.060
rna metabolic process GO:0016070 219 0.059
Zebrafish Mouse
multi organism reproductive process GO:0044703 36 0.059
macromolecule biosynthetic process GO:0009059 227 0.057
Zebrafish Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.056
regulation of neuron differentiation GO:0045664 56 0.056
guanosine containing compound metabolic process GO:1901068 4 0.056
cellular localization GO:0051641 97 0.056
single organism localization GO:1902578 225 0.056
cellular response to stress GO:0033554 62 0.056
lateral inhibition GO:0046331 1 0.056
organonitrogen compound metabolic process GO:1901564 74 0.056
phosphorus metabolic process GO:0006793 109 0.055
chordate embryonic development GO:0043009 271 0.055
cell surface receptor signaling pathway GO:0007166 325 0.055
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.055
Zebrafish
regulation of intracellular signal transduction GO:1902531 57 0.055
heart contraction GO:0060047 71 0.055
regulation of apoptotic process GO:0042981 98 0.055
regulation of localization GO:0032879 104 0.054
wound healing GO:0042060 90 0.054
Zebrafish
death GO:0016265 121 0.054
response to oxygen containing compound GO:1901700 55 0.054
synapse assembly GO:0007416 9 0.053
adult behavior GO:0030534 2 0.053
ion transport GO:0006811 114 0.053
muscle tissue development GO:0060537 110 0.053
regulation of synaptic plasticity GO:0048167 1 0.053
transcription dna templated GO:0006351 181 0.053
Zebrafish Mouse
gtp metabolic process GO:0046039 4 0.052
response to other organism GO:0051707 97 0.052
organelle fusion GO:0048284 3 0.052
retina morphogenesis in camera type eye GO:0060042 79 0.051
Zebrafish
cellular macromolecular complex assembly GO:0034622 24 0.051
metencephalon development GO:0022037 27 0.051
regulation of molecular function GO:0065009 70 0.051
regulation of protein transport GO:0051223 3 0.051
aging GO:0007568 2 0.051
muscle cell differentiation GO:0042692 139 0.051
macromolecular complex subunit organization GO:0043933 74 0.051
regulation of organelle organization GO:0033043 29 0.051
germ cell development GO:0007281 22 0.050
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.049
Zebrafish Mouse
negative regulation of cellular component organization GO:0051129 16 0.048
cell proliferation in forebrain GO:0021846 3 0.048
protein modification process GO:0036211 100 0.048
regulation of transcription dna templated GO:0006355 213 0.047
Zebrafish Mouse
nucleocytoplasmic transport GO:0006913 4 0.047
regulation of cell death GO:0010941 103 0.046
organelle localization GO:0051640 49 0.046
regulation of histone methylation GO:0031060 3 0.046
gamete generation GO:0007276 33 0.046
multicellular organismal reproductive process GO:0048609 35 0.045
regulation of chemotaxis GO:0050920 18 0.045
regulation of gene expression GO:0010468 265 0.045
Zebrafish Mouse
negative regulation of metabolic process GO:0009892 86 0.045
regulation of catalytic activity GO:0050790 55 0.044
sensory organ development GO:0007423 393 0.044
Zebrafish Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.044
cell growth GO:0016049 57 0.044
single organism metabolic process GO:0044710 217 0.044
regulation of dna templated transcription in response to stress GO:0043620 0 0.044
mitotic cell cycle GO:0000278 64 0.044
Zebrafish
regulation of protein complex assembly GO:0043254 3 0.043
single organism nuclear import GO:1902593 3 0.043
regulation of growth GO:0040008 42 0.043
positive regulation of cellular component biogenesis GO:0044089 3 0.043
negative regulation of macromolecule metabolic process GO:0010605 76 0.043
phosphorylation GO:0016310 69 0.042
regulation of cell cycle process GO:0010564 20 0.042
small gtpase mediated signal transduction GO:0007264 8 0.042
positive regulation of nucleic acid templated transcription GO:1903508 57 0.042
Zebrafish Mouse
protein import into nucleus GO:0006606 3 0.041
positive regulation of cellular catabolic process GO:0031331 3 0.041
innate immune response GO:0045087 13 0.041
histone modification GO:0016570 20 0.041
striated muscle tissue development GO:0014706 110 0.041
heart development GO:0007507 313 0.041
Zebrafish
cellular response to organic substance GO:0071310 105 0.040
Zebrafish
regulation of response to nutrient levels GO:0032107 1 0.040
developmental process involved in reproduction GO:0003006 27 0.040
regulation of establishment of protein localization GO:0070201 4 0.039
digestive tract morphogenesis GO:0048546 231 0.039
hemopoiesis GO:0030097 183 0.039
Zebrafish Mouse
actin polymerization or depolymerization GO:0008154 2 0.039
positive regulation of gene expression GO:0010628 71 0.039
Zebrafish Mouse
melanin metabolic process GO:0006582 2 0.039
anterior posterior pattern specification GO:0009952 152 0.039
Zebrafish
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.039
Zebrafish Mouse
positive regulation of protein metabolic process GO:0051247 23 0.038
embryonic skeletal system development GO:0048706 97 0.038
Zebrafish
digestive tract development GO:0048565 265 0.038
single organism cellular localization GO:1902580 46 0.038
pectoral fin morphogenesis GO:0035138 29 0.037
regulation of programmed cell death GO:0043067 101 0.037
protein polymerization GO:0051258 4 0.036
vasculature development GO:0001944 278 0.036
Zebrafish Mouse
cellular amine metabolic process GO:0044106 2 0.036
meiotic cell cycle process GO:1903046 3 0.036
regulation of protein localization to nucleus GO:1900180 2 0.036
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.036
cellular response to external stimulus GO:0071496 2 0.036
protein heterooligomerization GO:0051291 1 0.035
intracellular transport GO:0046907 32 0.035
regulation of macromolecule biosynthetic process GO:0010556 225 0.035
Zebrafish Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.034
Zebrafish Mouse
stem cell division GO:0017145 1 0.034
metal ion transport GO:0030001 58 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.034
gastrulation GO:0007369 208 0.034
protein localization to plasma membrane GO:0072659 1 0.034
mediolateral intercalation GO:0060031 3 0.034
regulation of cytokine production GO:0001817 3 0.034
macromolecular complex assembly GO:0065003 35 0.034
rho protein signal transduction GO:0007266 5 0.033
embryonic heart tube development GO:0035050 133 0.033
Zebrafish
dna metabolic process GO:0006259 27 0.033
spermatid differentiation GO:0048515 2 0.033
cell cell signaling GO:0007267 52 0.033
primary neural tube formation GO:0014020 1 0.032
single organism membrane fusion GO:0044801 2 0.032
signal transduction by phosphorylation GO:0023014 18 0.032
mesenchymal cell proliferation GO:0010463 1 0.032
response to uv GO:0009411 3 0.032
positive regulation of multicellular organismal process GO:0051240 52 0.032
Zebrafish
cellular ketone metabolic process GO:0042180 11 0.032
small molecule metabolic process GO:0044281 77 0.032
cation transport GO:0006812 81 0.032
sexual reproduction GO:0019953 36 0.032
startle response GO:0001964 4 0.031
ras protein signal transduction GO:0007265 7 0.031
regulation of carbohydrate metabolic process GO:0006109 4 0.031
regulation of protein metabolic process GO:0051246 56 0.031
single organism biosynthetic process GO:0044711 71 0.031
reproductive process GO:0022414 40 0.031
transcription from rna polymerase ii promoter GO:0006366 80 0.031
Zebrafish Mouse
spindle localization GO:0051653 12 0.031
cell migration involved in heart formation GO:0060974 10 0.031
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.030
neuroblast proliferation GO:0007405 2 0.030
tube closure GO:0060606 1 0.030
protein localization to nucleus GO:0034504 3 0.030
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.030
cellular carbohydrate metabolic process GO:0044262 4 0.030
regulation of establishment of planar polarity GO:0090175 4 0.030
regulation of stem cell differentiation GO:2000736 4 0.030
mitotic nuclear division GO:0007067 18 0.030
rna biosynthetic process GO:0032774 181 0.030
Zebrafish Mouse
sensory organ morphogenesis GO:0090596 200 0.030
Zebrafish
response to growth factor GO:0070848 39 0.029
Zebrafish
positive regulation of cell division GO:0051781 2 0.029
immune system development GO:0002520 191 0.029
Zebrafish Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.029
dendrite morphogenesis GO:0048813 5 0.029
macromolecule localization GO:0033036 54 0.029
regulation of dna metabolic process GO:0051052 11 0.028
establishment of organelle localization GO:0051656 45 0.028
regulation of cytoplasmic transport GO:1903649 4 0.028
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.028
homeostasis of number of cells GO:0048872 62 0.028
Zebrafish Mouse
developmental cell growth GO:0048588 52 0.028
negative regulation of kinase activity GO:0033673 4 0.028
protein import GO:0017038 3 0.028
regulation of cell migration GO:0030334 40 0.028
negative regulation of chromosome organization GO:2001251 1 0.028
cellular macromolecule localization GO:0070727 21 0.028
regulation of inflammatory response GO:0050727 2 0.027
ribonucleotide metabolic process GO:0009259 27 0.027
purine ribonucleotide metabolic process GO:0009150 27 0.027
positive regulation of programmed cell death GO:0043068 29 0.027
establishment of localization in cell GO:0051649 77 0.027
otic vesicle development GO:0071599 42 0.027
protein localization GO:0008104 40 0.027
pectoral fin development GO:0033339 50 0.027
regulation of intracellular protein transport GO:0033157 3 0.027
regulation of cell projection assembly GO:0060491 4 0.027
angioblast cell migration GO:0035476 9 0.027
Zebrafish
regulation of myotube differentiation GO:0010830 2 0.027
ribose phosphate metabolic process GO:0019693 27 0.027
spinal cord anterior posterior patterning GO:0021512 1 0.026
regulation of membrane potential GO:0042391 23 0.026
nephron morphogenesis GO:0072028 2 0.026
embryonic limb morphogenesis GO:0030326 2 0.026
myeloid cell differentiation GO:0030099 86 0.026
Zebrafish Mouse
negative regulation of protein kinase activity GO:0006469 4 0.026
negative regulation of mapk cascade GO:0043409 4 0.026
positive regulation of protein complex assembly GO:0031334 2 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.025
negative regulation of multicellular organismal process GO:0051241 69 0.025
cellular response to growth factor stimulus GO:0071363 39 0.025
Zebrafish
cellular response to endogenous stimulus GO:0071495 68 0.025
Zebrafish
b cell activation GO:0042113 2 0.025
cellular protein complex assembly GO:0043623 19 0.025
cytoskeleton organization GO:0007010 96 0.025
positive regulation of cell cycle GO:0045787 3 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
regulation of cell proliferation GO:0042127 37 0.025
Zebrafish
regulation of cellular component movement GO:0051270 55 0.025
nephron tubule morphogenesis GO:0072078 1 0.025
hepaticobiliary system development GO:0061008 98 0.025
negative regulation of transcription dna templated GO:0045892 45 0.025
regulation of cell projection organization GO:0031344 44 0.025
negative regulation of synapse assembly GO:0051964 2 0.025
cell fate commitment GO:0045165 99 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.025
Zebrafish Mouse
action potential GO:0001508 19 0.025
cellular protein modification process GO:0006464 100 0.025
response to external biotic stimulus GO:0043207 97 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
determination of left right symmetry GO:0007368 179 0.024
Zebrafish
regulation of cellular protein metabolic process GO:0032268 52 0.024
reproduction GO:0000003 40 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.024
nuclear division GO:0000280 23 0.024
internal protein amino acid acetylation GO:0006475 2 0.024
regulation of axon extension GO:0030516 24 0.024
programmed cell death GO:0012501 119 0.024
regulation of mitotic cell cycle GO:0007346 25 0.024
oxoacid metabolic process GO:0043436 31 0.024
positive regulation of apoptotic signaling pathway GO:2001235 1 0.024
negative regulation of cellular metabolic process GO:0031324 77 0.024
lamellipodium assembly GO:0030032 1 0.023
regulation of response to biotic stimulus GO:0002831 2 0.023
insulin like growth factor receptor signaling pathway GO:0048009 4 0.023
fatty acid oxidation GO:0019395 1 0.023
cardiac cell fate commitment GO:0060911 1 0.023
nuclear import GO:0051170 3 0.023
hard palate development GO:0060022 4 0.023
regulation of cellular component size GO:0032535 30 0.023
development of primary female sexual characteristics GO:0046545 4 0.023
cellular response to dna damage stimulus GO:0006974 24 0.023
negative regulation of rna biosynthetic process GO:1902679 45 0.023
embryonic digestive tract morphogenesis GO:0048557 3 0.023
negative regulation of defense response GO:0031348 2 0.023
wnt signaling pathway GO:0016055 80 0.023
regulation of gtp catabolic process GO:0033124 2 0.023
response to light stimulus GO:0009416 46 0.023
cation transmembrane transport GO:0098655 65 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.023
cell cycle g1 s phase transition GO:0044843 1 0.023
Zebrafish
lamellipodium organization GO:0097581 1 0.023
regulation of transporter activity GO:0032409 2 0.023
autophagy GO:0006914 4 0.022
nucleobase containing small molecule metabolic process GO:0055086 32 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.022
synaptic vesicle localization GO:0097479 1 0.022
positive regulation of molecular function GO:0044093 33 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
b cell differentiation GO:0030183 1 0.022
organic substance catabolic process GO:1901575 28 0.022
protein acetylation GO:0006473 2 0.022
cellular response to molecule of bacterial origin GO:0071219 3 0.022
regulation of phosphorus metabolic process GO:0051174 43 0.022
vesicle mediated transport GO:0016192 22 0.022
skin development GO:0043588 54 0.022
regulation of developmental growth GO:0048638 38 0.022
female gonad development GO:0008585 4 0.022
regulation of skeletal muscle tissue development GO:0048641 4 0.021
positive regulation of dna metabolic process GO:0051054 1 0.021
regulation of bone remodeling GO:0046850 2 0.021
nucleotide metabolic process GO:0009117 28 0.021
determination of heart left right asymmetry GO:0061371 117 0.021
Zebrafish
phosphatidylinositol mediated signaling GO:0048015 2 0.021
negative regulation of immune response GO:0050777 2 0.021
positive regulation of secretion by cell GO:1903532 1 0.021
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.021
g1 s transition of mitotic cell cycle GO:0000082 1 0.021
Zebrafish
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
regulation of mrna processing GO:0050684 3 0.021
regulation of wnt signaling pathway GO:0030111 53 0.021
segmentation GO:0035282 97 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.020
organic cyclic compound catabolic process GO:1901361 15 0.020
meiotic chromosome segregation GO:0045132 3 0.020
regulation of cell development GO:0060284 100 0.020
i kappab kinase nf kappab signaling GO:0007249 4 0.020
otic vesicle morphogenesis GO:0071600 34 0.020
response to abiotic stimulus GO:0009628 122 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
gland development GO:0048732 143 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
cartilage condensation GO:0001502 3 0.020
forebrain cell migration GO:0021885 1 0.019
amine metabolic process GO:0009308 2 0.019
determination of bilateral symmetry GO:0009855 204 0.019
Zebrafish
actin cytoskeleton organization GO:0030036 63 0.019
single organism reproductive process GO:0044702 40 0.019
regulation of locomotion GO:0040012 55 0.019
cellular response to nutrient levels GO:0031669 2 0.019
neuron projection extension GO:1990138 45 0.019
lymphocyte proliferation GO:0046651 1 0.019
neurotransmitter transport GO:0006836 2 0.019
organelle fission GO:0048285 23 0.019

pknox1.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.123
myopathy DOID:423 0 0.099
muscular disease DOID:0080000 0 0.099
musculoskeletal system disease DOID:17 0 0.099
muscle tissue disease DOID:66 0 0.099
disease of metabolism DOID:0014667 0 0.031
inherited metabolic disorder DOID:655 0 0.031
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.029
nervous system disease DOID:863 0 0.029