Danio rerio

0 known processes

tagap

T-cell activation GTPase activating protein

(Aliases: si:ch211-122h15.1,zgc:92103)

tagap biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.075
aging GO:0007568 2 0.069
cognition GO:0050890 1 0.054
amine metabolic process GO:0009308 2 0.050
cellular amine metabolic process GO:0044106 2 0.045
regulation of cellular amine metabolic process GO:0033238 0 0.044
regulation of cell shape GO:0008360 1 0.040
generation of neurons GO:0048699 385 0.039
establishment of protein localization to organelle GO:0072594 4 0.039
regulation of primary metabolic process GO:0080090 311 0.039
cellular ketone metabolic process GO:0042180 11 0.038
positive regulation of cell cycle GO:0045787 3 0.037
signal transduction GO:0007165 455 0.035
phagocytosis GO:0006909 3 0.035
positive regulation of transport GO:0051050 2 0.035
regulation of metabolic process GO:0019222 359 0.034
regulation of multicellular organism growth GO:0040014 4 0.034
regulation of macromolecule biosynthetic process GO:0010556 225 0.033
cellular amino acid metabolic process GO:0006520 7 0.033
multicellular organism growth GO:0035264 4 0.033
regulation of cellular ketone metabolic process GO:0010565 7 0.032
negative regulation of biological process GO:0048519 304 0.032
single organism metabolic process GO:0044710 217 0.031
chemosensory behavior GO:0007635 1 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.031
carboxylic acid metabolic process GO:0019752 22 0.031
negative regulation of protein kinase activity GO:0006469 4 0.031
negative regulation of kinase activity GO:0033673 4 0.030
purine nucleoside monophosphate catabolic process GO:0009128 4 0.030
neuron differentiation GO:0030182 353 0.030
organic acid metabolic process GO:0006082 31 0.030
negative regulation of protein phosphorylation GO:0001933 4 0.030
maintenance of location GO:0051235 4 0.030
regulation of synapse organization GO:0050807 3 0.030
cellular biosynthetic process GO:0044249 286 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
adult behavior GO:0030534 2 0.029
synaptic growth at neuromuscular junction GO:0051124 2 0.029
exocytosis GO:0006887 1 0.029
regulation of protein complex assembly GO:0043254 3 0.029
regulation of cellular metabolic process GO:0031323 320 0.029
regulation of developmental process GO:0050793 247 0.029
biosynthetic process GO:0009058 294 0.028
modification dependent protein catabolic process GO:0019941 3 0.028
negative regulation of cellular process GO:0048523 283 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
neuron development GO:0048666 262 0.028
cellular nitrogen compound metabolic process GO:0034641 290 0.028
oxoacid metabolic process GO:0043436 31 0.028
cellular component morphogenesis GO:0032989 336 0.028
regulation of macromolecule metabolic process GO:0060255 317 0.027
nuclear transport GO:0051169 4 0.027
modification dependent macromolecule catabolic process GO:0043632 3 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
morphogenesis of an epithelium GO:0002009 333 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
cellular macromolecule metabolic process GO:0044260 391 0.027
cellular protein catabolic process GO:0044257 4 0.027
regulation of synaptic plasticity GO:0048167 1 0.027
cell projection organization GO:0030030 284 0.027
organic substance biosynthetic process GO:1901576 289 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
autophagy GO:0006914 4 0.026
regulation of biological quality GO:0065008 263 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.025
protein import GO:0017038 3 0.025
response to drug GO:0042493 3 0.025
cellular response to external stimulus GO:0071496 2 0.024
response to chemical GO:0042221 320 0.024
atp catabolic process GO:0006200 4 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
positive regulation of protein complex assembly GO:0031334 2 0.023
gtp catabolic process GO:0006184 2 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
regulation of mrna processing GO:0050684 3 0.023
cell part morphogenesis GO:0032990 246 0.023
small molecule metabolic process GO:0044281 77 0.023
protein acetylation GO:0006473 2 0.023
protein import into nucleus GO:0006606 3 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
cell projection morphogenesis GO:0048858 244 0.023
protein localization to nucleus GO:0034504 3 0.023
positive regulation of catabolic process GO:0009896 4 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.022
regulation of cytokine production GO:0001817 3 0.022
regulation of gene expression GO:0010468 265 0.022
regulation of biosynthetic process GO:0009889 250 0.022
protein localization to plasma membrane GO:0072659 1 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
sensory organ development GO:0007423 393 0.022
organelle fusion GO:0048284 3 0.022
regulation of autophagy GO:0010506 3 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
spermatid development GO:0007286 2 0.022
gtp metabolic process GO:0046039 4 0.022
regulation of metal ion transport GO:0010959 4 0.022
protein dephosphorylation GO:0006470 3 0.022
negative regulation of catabolic process GO:0009895 3 0.021
organelle organization GO:0006996 227 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.021
regulation of sequestering of calcium ion GO:0051282 4 0.021
regionalization GO:0003002 274 0.021
cytokinesis GO:0000910 3 0.021
neuron neuron synaptic transmission GO:0007270 1 0.021
regulation of signal transduction GO:0009966 225 0.021
regulation of reactive oxygen species metabolic process GO:2000377 2 0.021
stem cell proliferation GO:0072089 4 0.021
nuclear import GO:0051170 3 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
regulation of cell communication GO:0010646 232 0.021
cellular component disassembly GO:0022411 1 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
response to external stimulus GO:0009605 264 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
response to carbohydrate GO:0009743 3 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
meiotic nuclear division GO:0007126 4 0.020
single organism nuclear import GO:1902593 3 0.020
regulation of mrna splicing via spliceosome GO:0048024 3 0.020
sequestering of metal ion GO:0051238 3 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
macromolecular complex disassembly GO:0032984 1 0.020
synaptic vesicle transport GO:0048489 1 0.020
transcription dna templated GO:0006351 181 0.020
regulation of signaling GO:0023051 235 0.019
positive regulation of biological process GO:0048518 253 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
lipid storage GO:0019915 1 0.019
regulation of binding GO:0051098 3 0.019
positive regulation of cytoskeleton organization GO:0051495 3 0.019
protein metabolic process GO:0019538 183 0.019
single organism membrane fusion GO:0044801 2 0.019
mitochondrion organization GO:0007005 4 0.019
membrane fusion GO:0061025 2 0.019
response to stress GO:0006950 263 0.019
rna biosynthetic process GO:0032774 181 0.019
leukocyte proliferation GO:0070661 1 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.019
regulation of response to stimulus GO:0048583 269 0.019
cell morphogenesis GO:0000902 289 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
regulation of cell activation GO:0050865 1 0.018
rna localization GO:0006403 4 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
tube morphogenesis GO:0035239 349 0.018
negative regulation of cellular catabolic process GO:0031330 3 0.018
regulation of protein transport GO:0051223 3 0.018
homeostatic process GO:0042592 142 0.018
b cell activation GO:0042113 2 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
cellular response to nutrient levels GO:0031669 2 0.018
sequestering of calcium ion GO:0051208 3 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
regulation of erk1 and erk2 cascade GO:0070372 4 0.018
negative regulation of cytokine production GO:0001818 1 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
nucleic acid templated transcription GO:0097659 181 0.017
immune system process GO:0002376 241 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
actin polymerization or depolymerization GO:0008154 2 0.017
response to biotic stimulus GO:0009607 97 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
protein targeting to nucleus GO:0044744 3 0.017
tissue remodeling GO:0048771 4 0.017
protein acylation GO:0043543 3 0.017
negative regulation of signal transduction GO:0009968 94 0.017
meiotic cell cycle process GO:1903046 3 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
cellular response to starvation GO:0009267 1 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
response to corticosteroid GO:0031960 1 0.017
positive regulation of cellular process GO:0048522 201 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
protein complex disassembly GO:0043241 1 0.017
neuron projection development GO:0031175 180 0.017
system process GO:0003008 185 0.016
anterior posterior pattern specification GO:0009952 152 0.016
neuron projection morphogenesis GO:0048812 161 0.016
rna metabolic process GO:0016070 219 0.016
protein stabilization GO:0050821 2 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
nucleic acid metabolic process GO:0090304 244 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
endosomal transport GO:0016197 2 0.016
apoptotic process GO:0006915 116 0.016
regulation of cell differentiation GO:0045595 142 0.016
heart development GO:0007507 313 0.016
regulation of synapse assembly GO:0051963 3 0.016
regulation of intracellular protein transport GO:0033157 3 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
synaptic vesicle localization GO:0097479 1 0.015
cellular component movement GO:0006928 335 0.015
single organism organelle organization GO:1902589 199 0.015
establishment of localization GO:0051234 244 0.015
central nervous system development GO:0007417 387 0.015
axon development GO:0061564 166 0.015
protein secretion GO:0009306 1 0.015
regulation of protein catabolic process GO:0042176 1 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
regulation of rna metabolic process GO:0051252 224 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
cellular protein metabolic process GO:0044267 129 0.015
regulation of dendrite development GO:0050773 3 0.015
regulation of receptor activity GO:0010469 2 0.015
regulation of dna replication GO:0006275 3 0.015
digestive tract development GO:0048565 265 0.015
negative regulation of cell communication GO:0010648 96 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
multi organism process GO:0051704 134 0.015
axonogenesis GO:0007409 152 0.015
positive regulation of secretion GO:0051047 1 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
sensory organ morphogenesis GO:0090596 200 0.015
cellular response to extracellular stimulus GO:0031668 2 0.014
positive regulation of metabolic process GO:0009893 108 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
positive regulation of cell activation GO:0050867 1 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
striated muscle tissue development GO:0014706 110 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
positive regulation of cytokine production GO:0001819 2 0.014
negative regulation of mitosis GO:0045839 3 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
cellular response to oxygen levels GO:0071453 1 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
peptidyl serine modification GO:0018209 2 0.014
maternal determination of anterior posterior axis embryo GO:0008358 4 0.014
regulation of calcium ion transport GO:0051924 2 0.014
protein polyubiquitination GO:0000209 4 0.014
cytosolic calcium ion transport GO:0060401 3 0.014
multicellular organismal metabolic process GO:0044236 2 0.014
negative regulation of sequestering of calcium ion GO:0051283 4 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
gene expression GO:0010467 252 0.014
convergent extension GO:0060026 118 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
calcium ion transport into cytosol GO:0060402 3 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
gastrulation GO:0007369 208 0.014
heterocycle metabolic process GO:0046483 290 0.014
embryonic organ development GO:0048568 381 0.014
cell substrate adhesion GO:0031589 4 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
stem cell maintenance GO:0019827 4 0.014
regulation of reproductive process GO:2000241 4 0.014
mitotic dna damage checkpoint GO:0044773 4 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
regulation of protein complex disassembly GO:0043244 1 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
neurotransmitter transport GO:0006836 2 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
spermatid differentiation GO:0048515 2 0.013
cell death GO:0008219 121 0.013
muscle structure development GO:0061061 196 0.013
regulation of muscle contraction GO:0006937 3 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
intracellular mrna localization GO:0008298 1 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
single fertilization GO:0007338 3 0.013
response to uv GO:0009411 3 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
head development GO:0060322 303 0.013
growth GO:0040007 174 0.013
locomotion GO:0040011 313 0.013
brain development GO:0007420 293 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
digestive system development GO:0055123 289 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
actin filament polymerization GO:0030041 2 0.013
release of sequestered calcium ion into cytosol GO:0051209 3 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
mononuclear cell proliferation GO:0032943 1 0.013
regulation of gtpase activity GO:0043087 2 0.013
regulation of exocytosis GO:0017157 1 0.013
lymphocyte proliferation GO:0046651 1 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
negative regulation of metabolic process GO:0009892 86 0.013
mitochondrial transport GO:0006839 2 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
neurotransmitter secretion GO:0007269 2 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
single organism localization GO:1902578 225 0.013
chordate embryonic development GO:0043009 271 0.013
cortical actin cytoskeleton organization GO:0030866 1 0.012
negative regulation of signaling GO:0023057 96 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
developmental growth GO:0048589 166 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
ameboidal type cell migration GO:0001667 143 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
regulation of wound healing GO:0061041 2 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
intracellular signal transduction GO:0035556 85 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of jun kinase activity GO:0043506 3 0.012
developmental programmed cell death GO:0010623 4 0.012
regulation of oocyte development GO:0060281 3 0.012
positive regulation of translation GO:0045727 1 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
carbohydrate homeostasis GO:0033500 1 0.012
stem cell division GO:0017145 1 0.012
cilium morphogenesis GO:0060271 85 0.012
nuclear export GO:0051168 1 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
cytoplasm organization GO:0007028 4 0.012
secondary metabolic process GO:0019748 3 0.012
phagocytosis engulfment GO:0006911 1 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
regulation of jak stat cascade GO:0046425 3 0.012
response to glucocorticoid GO:0051384 1 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
protein heterooligomerization GO:0051291 1 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
regulation of organ growth GO:0046620 3 0.012
neuroblast proliferation GO:0007405 2 0.012
striated muscle cell development GO:0055002 108 0.012
compound eye development GO:0048749 2 0.012
protein targeting to membrane GO:0006612 1 0.012
fertilization GO:0009566 3 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
superoxide metabolic process GO:0006801 2 0.012
regulation of protein targeting GO:1903533 2 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
muscle cell development GO:0055001 115 0.012
response to hexose GO:0009746 3 0.012
lateral inhibition GO:0046331 1 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
adherens junction organization GO:0034332 4 0.011
membrane invagination GO:0010324 1 0.011
response to hydrogen peroxide GO:0042542 3 0.011
cell cycle arrest GO:0007050 1 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
blood vessel development GO:0001568 246 0.011
protein depolymerization GO:0051261 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
activation of mapk activity GO:0000187 3 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
cellular response to radiation GO:0071478 4 0.011
cell migration GO:0016477 237 0.011
cellular response to light stimulus GO:0071482 4 0.011
macromolecule modification GO:0043412 111 0.011
response to monosaccharide GO:0034284 3 0.011
regulation of chromosome segregation GO:0051983 1 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
cellular respiration GO:0045333 3 0.011
alternative mrna splicing via spliceosome GO:0000380 1 0.011
mitotic cytokinesis GO:0000281 3 0.011
programmed cell death GO:0012501 119 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
organic acid catabolic process GO:0016054 3 0.011
negative regulation of nuclear division GO:0051784 3 0.011
cellular protein modification process GO:0006464 100 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
single organism transport GO:0044765 206 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
response to organic substance GO:0010033 153 0.011
behavior GO:0007610 74 0.011
cellular response to hypoxia GO:0071456 1 0.011
regulation of transporter activity GO:0032409 2 0.011
golgi vesicle transport GO:0048193 3 0.011
cellular amide metabolic process GO:0043603 4 0.011
rna 3 end processing GO:0031123 2 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
tube closure GO:0060606 1 0.010
single organism biosynthetic process GO:0044711 71 0.010
transport GO:0006810 220 0.010
regulation of protein polymerization GO:0032271 2 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
centrosome cycle GO:0007098 1 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
primary neural tube formation GO:0014020 1 0.010
cellular protein complex disassembly GO:0043624 1 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
organism emergence from protective structure GO:0071684 4 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
glucose homeostasis GO:0042593 1 0.010
response to unfolded protein GO:0006986 2 0.010
digestive tract morphogenesis GO:0048546 231 0.010
regulation of cellular component organization GO:0051128 86 0.010
pole plasm assembly GO:0007315 4 0.010
somatic stem cell maintenance GO:0035019 1 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010

tagap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.023
immune system disease DOID:2914 0 0.018
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.015
disease of metabolism DOID:0014667 0 0.014
musculoskeletal system disease DOID:17 0 0.014
inherited metabolic disorder DOID:655 0 0.010
sensory system disease DOID:0050155 0 0.010