Danio rerio

43 known processes

fshr

follicle stimulating hormone receptor

(Aliases: GTHR-I,zfGTHR-I)

fshr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cyclic nucleotide biosynthetic process GO:0009190 18 0.409
ion transport GO:0006811 114 0.366
regulation of hormone secretion GO:0046883 2 0.302
purine nucleotide biosynthetic process GO:0006164 20 0.295
nucleotide biosynthetic process GO:0009165 21 0.277
organic cyclic compound metabolic process GO:1901360 301 0.242
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.236
Mouse
long chain fatty acid transport GO:0015909 1 0.222
morphogenesis of an epithelium GO:0002009 333 0.219
establishment of localization GO:0051234 244 0.216
Rat
female sex differentiation GO:0046660 4 0.208
single organism localization GO:1902578 225 0.195
Rat
cellular response to antibiotic GO:0071236 1 0.188
response to corticosteroid GO:0031960 1 0.144
organic cyclic compound biosynthetic process GO:1901362 223 0.140
regulation of metal ion transport GO:0010959 4 0.139
ovarian follicle development GO:0001541 2 0.138
transport GO:0006810 220 0.135
Rat
ribonucleotide biosynthetic process GO:0009260 20 0.129
signal transduction GO:0007165 455 0.129
regulation of rna metabolic process GO:0051252 224 0.128
cation transport GO:0006812 81 0.118
hormone mediated signaling pathway GO:0009755 9 0.112
regulation of localization GO:0032879 104 0.110
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.107
hormone secretion GO:0046879 2 0.106
positive regulation of camp biosynthetic process GO:0030819 2 0.101
alcohol biosynthetic process GO:0046165 2 0.100
regulation of transport GO:0051049 45 0.097
cell cell signaling GO:0007267 52 0.097
Mouse
cation homeostasis GO:0055080 33 0.096
cyclic nucleotide metabolic process GO:0009187 18 0.095
regulation of primary metabolic process GO:0080090 311 0.094
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.093
Mouse
transcription dna templated GO:0006351 181 0.093
digestive tract development GO:0048565 265 0.092
organic substance biosynthetic process GO:1901576 289 0.091
establishment of localization in cell GO:0051649 77 0.088
response to organic cyclic compound GO:0014070 51 0.088
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 5 0.087
Mouse Rat
ubiquitin dependent protein catabolic process GO:0006511 3 0.086
hormone biosynthetic process GO:0042446 3 0.085
single organism transport GO:0044765 206 0.085
Rat
response to organic substance GO:0010033 153 0.082
regulation of biological quality GO:0065008 263 0.081
Mouse
head development GO:0060322 303 0.080
cellular protein catabolic process GO:0044257 4 0.080
single organism metabolic process GO:0044710 217 0.077
Mouse
maintenance of location GO:0051235 4 0.076
meiotic chromosome segregation GO:0045132 3 0.075
oocyte maturation GO:0001556 4 0.071
regulation of response to stimulus GO:0048583 269 0.071
Mouse
female gonad development GO:0008585 4 0.070
system process GO:0003008 185 0.070
Mouse
regulation of cytoplasmic transport GO:1903649 4 0.070
nucleobase containing compound metabolic process GO:0006139 274 0.069
Mouse
rna metabolic process GO:0016070 219 0.068
regulation of signaling GO:0023051 235 0.068
Mouse
ribose phosphate biosynthetic process GO:0046390 20 0.068
carbohydrate derivative metabolic process GO:1901135 61 0.067
negative regulation of secretion GO:0051048 2 0.067
heterocycle biosynthetic process GO:0018130 215 0.066
regulation of cyclase activity GO:0031279 12 0.065
modification dependent protein catabolic process GO:0019941 3 0.064
regulation of sodium ion transport GO:0002028 2 0.063
positive regulation of transport GO:0051050 2 0.062
regulation of metabolic process GO:0019222 359 0.061
Mouse
purine nucleotide metabolic process GO:0006163 27 0.059
lysosomal transport GO:0007041 2 0.059
fatty acid transport GO:0015908 1 0.057
single organism biosynthetic process GO:0044711 71 0.057
digestive system development GO:0055123 289 0.056
positive regulation of camp metabolic process GO:0030816 2 0.055
cognition GO:0050890 1 0.054
neurological system process GO:0050877 62 0.054
positive regulation of cellular biosynthetic process GO:0031328 68 0.054
response to glucocorticoid GO:0051384 1 0.054
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.054
regulation of signal transduction GO:0009966 225 0.054
Mouse
positive regulation of signal transduction GO:0009967 56 0.053
Mouse
regionalization GO:0003002 274 0.053
protein targeting to vacuole GO:0006623 1 0.053
male gamete generation GO:0048232 7 0.052
Mouse
regulation of nucleotide biosynthetic process GO:0030808 15 0.052
modification dependent macromolecule catabolic process GO:0043632 3 0.051
biosynthetic process GO:0009058 294 0.051
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.050
sensory organ development GO:0007423 393 0.050
sequestering of metal ion GO:0051238 3 0.049
meiotic cell cycle process GO:1903046 3 0.049
regulation of reproductive process GO:2000241 4 0.049
meiotic nuclear division GO:0007126 4 0.049
tube morphogenesis GO:0035239 349 0.049
inositol phosphate metabolic process GO:0043647 1 0.048
proteasomal protein catabolic process GO:0010498 2 0.046
negative regulation of hormone secretion GO:0046888 2 0.046
rhythmic process GO:0048511 21 0.046
regulation of cell communication GO:0010646 232 0.045
Mouse
purine ribonucleotide biosynthetic process GO:0009152 20 0.045
purine containing compound biosynthetic process GO:0072522 20 0.045
defense response GO:0006952 47 0.045
Worm
hormone transport GO:0009914 2 0.045
chromosome organization involved in meiosis GO:0070192 1 0.044
nucleotide metabolic process GO:0009117 28 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.044
metal ion transport GO:0030001 58 0.043
cellular response to toxic substance GO:0097237 1 0.042
nucleic acid metabolic process GO:0090304 244 0.042
Mouse
positive regulation of transcription dna templated GO:0045893 57 0.040
regulation of lyase activity GO:0051339 12 0.040
cyclic purine nucleotide metabolic process GO:0052652 18 0.039
multicellular organism growth GO:0035264 4 0.039
regulation of hormone levels GO:0010817 21 0.039
Mouse
camp metabolic process GO:0046058 11 0.039
cell cycle g1 s phase transition GO:0044843 1 0.039
nephron tubule morphogenesis GO:0072078 1 0.038
regulation of gene expression GO:0010468 265 0.038
cell surface receptor signaling pathway GO:0007166 325 0.038
eye development GO:0001654 277 0.038
regulation of biosynthetic process GO:0009889 250 0.037
negative regulation of feeding behavior GO:2000252 2 0.037
determination of heart left right asymmetry GO:0061371 117 0.037
small molecule biosynthetic process GO:0044283 16 0.037
central nervous system development GO:0007417 387 0.037
aromatic compound biosynthetic process GO:0019438 217 0.037
response to chemical GO:0042221 320 0.036
negative regulation of secretion by cell GO:1903531 2 0.036
cellular response to hormone stimulus GO:0032870 39 0.036
regulation of transcription dna templated GO:0006355 213 0.036
cellular biosynthetic process GO:0044249 286 0.036
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.036
epithelial tube morphogenesis GO:0060562 148 0.036
reproductive process GO:0022414 40 0.036
regulation of camp metabolic process GO:0030814 9 0.035
digestive tract morphogenesis GO:0048546 231 0.035
spemann organizer formation at the embryonic shield GO:0060063 2 0.035
response to antibiotic GO:0046677 1 0.034
meiosis i GO:0007127 1 0.034
regulation of system process GO:0044057 40 0.034
g protein coupled receptor signaling pathway GO:0007186 74 0.034
nitrogen compound metabolic process GO:0006807 319 0.034
Mouse
cellular response to organic cyclic compound GO:0071407 38 0.034
regulation of camp biosynthetic process GO:0030817 9 0.034
adrenal gland development GO:0030325 10 0.033
reproduction GO:0000003 40 0.033
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
Mouse
myotube cell development GO:0014904 35 0.032
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.032
cellular response to endogenous stimulus GO:0071495 68 0.031
regulation of chromosome segregation GO:0051983 1 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
glucocorticoid metabolic process GO:0008211 2 0.030
polyol metabolic process GO:0019751 1 0.030
cellular response to organic substance GO:0071310 105 0.029
pathway restricted smad protein phosphorylation GO:0060389 1 0.029
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.029
calcium ion transport into cytosol GO:0060402 3 0.029
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.029
organonitrogen compound biosynthetic process GO:1901566 47 0.029
heterocycle metabolic process GO:0046483 290 0.029
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
multi organism process GO:0051704 134 0.029
Mouse
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.029
regulation of multicellular organismal process GO:0051239 277 0.028
Mouse
gene expression GO:0010467 252 0.028
regulation of sequestering of calcium ion GO:0051282 4 0.028
signal transduction in absence of ligand GO:0038034 1 0.028
extrinsic apoptotic signaling pathway GO:0097191 3 0.028
response to xenobiotic stimulus GO:0009410 45 0.027
growth GO:0040007 174 0.027
positive regulation of biosynthetic process GO:0009891 68 0.027
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.027
organophosphate biosynthetic process GO:0090407 23 0.027
developmental growth GO:0048589 166 0.027
monovalent inorganic cation transport GO:0015672 42 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
Mouse
lipid storage GO:0019915 1 0.026
regulation of ion transport GO:0043269 22 0.026
negative regulation of cellular catabolic process GO:0031330 3 0.026
immune system process GO:0002376 241 0.026
Mouse
nucleoside phosphate biosynthetic process GO:1901293 21 0.026
skeletal system development GO:0001501 181 0.025
protein metabolic process GO:0019538 183 0.025
Mouse
adult behavior GO:0030534 2 0.025
negative regulation of biological process GO:0048519 304 0.025
Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.025
larval development GO:0002164 2 0.025
opioid receptor signaling pathway GO:0038003 3 0.024
negative regulation of multicellular organismal process GO:0051241 69 0.024
Mouse
striated muscle cell development GO:0055002 108 0.024
hormone metabolic process GO:0042445 19 0.023
Mouse
regulation of multicellular organism growth GO:0040014 4 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
Mouse
connective tissue development GO:0061448 99 0.023
homeostatic process GO:0042592 142 0.023
Mouse
negative regulation of nuclear division GO:0051784 3 0.023
developmental process involved in reproduction GO:0003006 27 0.023
spermatogenesis GO:0007283 7 0.022
Mouse
epiboly GO:0090504 41 0.022
negative regulation of oocyte development GO:0060283 2 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
Mouse
nucleic acid templated transcription GO:0097659 181 0.022
regulation of phosphorus metabolic process GO:0051174 43 0.022
Mouse
camera type eye development GO:0043010 222 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
brain development GO:0007420 293 0.022
response to hormone GO:0009725 48 0.022
multicellular organismal reproductive process GO:0048609 35 0.022
cellular localization GO:0051641 97 0.021
peptide transport GO:0015833 1 0.021
secondary metabolic process GO:0019748 3 0.021
positive regulation of cell communication GO:0010647 56 0.021
Mouse
regulation of blood pressure GO:0008217 1 0.021
Mouse
single organism reproductive process GO:0044702 40 0.021
aging GO:0007568 2 0.021
macromolecule biosynthetic process GO:0009059 227 0.020
positive regulation of blood circulation GO:1903524 2 0.020
response to drug GO:0042493 3 0.020
response to ketone GO:1901654 1 0.020
gastrulation GO:0007369 208 0.020
male meiosis GO:0007140 2 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
response to alkaloid GO:0043279 2 0.020
positive regulation of cell division GO:0051781 2 0.020
carbohydrate biosynthetic process GO:0016051 1 0.019
embryonic heart tube development GO:0035050 133 0.019
positive regulation of rna metabolic process GO:0051254 59 0.019
single organism organelle organization GO:1902589 199 0.019
Mouse
intracellular signal transduction GO:0035556 85 0.019
Mouse
positive regulation of metabolic process GO:0009893 108 0.019
cellular lipid catabolic process GO:0044242 3 0.019
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 5 0.019
Mouse Rat
proteolysis GO:0006508 38 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.018
female meiosis chromosome segregation GO:0016321 1 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
nuclear transport GO:0051169 4 0.018
cell proliferation GO:0008283 80 0.018
Mouse
camp biosynthetic process GO:0006171 11 0.018
small molecule metabolic process GO:0044281 77 0.018
cellular nitrogen compound metabolic process GO:0034641 290 0.018
Mouse
cytokinesis GO:0000910 3 0.018
behavior GO:0007610 74 0.017
Mouse
c21 steroid hormone metabolic process GO:0008207 1 0.017
determination of ventral identity GO:0048264 21 0.017
cellular response to estradiol stimulus GO:0071392 1 0.017
spermatid development GO:0007286 2 0.017
Mouse
cytosolic calcium ion transport GO:0060401 3 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
forebrain development GO:0030900 96 0.017
muscle fiber development GO:0048747 52 0.017
specification of symmetry GO:0009799 204 0.016
positive regulation of cell cycle GO:0045787 3 0.016
positive regulation of stem cell proliferation GO:2000648 1 0.016
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.016
Mouse
regulation of camp mediated signaling GO:0043949 1 0.016
cellular protein metabolic process GO:0044267 129 0.016
Mouse
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
positive regulation of neural precursor cell proliferation GO:2000179 1 0.015
release of sequestered calcium ion into cytosol GO:0051209 3 0.015
ovulation cycle process GO:0022602 2 0.015
gastrulation with mouth forming second GO:0001702 44 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
regulation of bmp signaling pathway GO:0030510 39 0.015
organelle organization GO:0006996 227 0.015
Mouse
multicellular organism reproduction GO:0032504 35 0.015
sodium ion transport GO:0006814 24 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
nephron morphogenesis GO:0072028 2 0.015
retina development in camera type eye GO:0060041 146 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
heart looping GO:0001947 94 0.014
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
cell death GO:0008219 121 0.014
regulation of embryonic development GO:0045995 47 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
regulation of carbohydrate biosynthetic process GO:0043255 1 0.014
regulation of oocyte development GO:0060281 3 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
chondrocyte intercalation involved in growth plate cartilage morphogenesis GO:0003428 1 0.014
positive regulation of myeloid cell differentiation GO:0045639 2 0.014
limbic system development GO:0021761 16 0.014
regulation of molecular function GO:0065009 70 0.013
regulation of apoptotic process GO:0042981 98 0.013
apoptotic process GO:0006915 116 0.013
regulation of cell death GO:0010941 103 0.013
positive regulation of signaling GO:0023056 56 0.013
Mouse
nucleobase containing small molecule metabolic process GO:0055086 32 0.013
nephron epithelium morphogenesis GO:0072088 1 0.013
ovulation cycle GO:0042698 2 0.013
urogenital system development GO:0001655 97 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.013
segmentation GO:0035282 97 0.013
mesoderm development GO:0007498 88 0.013
regulation of calcium ion transport GO:0051924 2 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.013
eye morphogenesis GO:0048592 144 0.013
determination of bilateral symmetry GO:0009855 204 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
erythrocyte differentiation GO:0030218 54 0.013
regulation of cell fate commitment GO:0010453 22 0.013
carbohydrate derivative biosynthetic process GO:1901137 43 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
cell cycle arrest GO:0007050 1 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
gland development GO:0048732 143 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
odontogenesis of dentin containing tooth GO:0042475 1 0.012
cardiogenic plate morphogenesis GO:0003142 1 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
negative regulation of mitosis GO:0045839 3 0.012
stem cell division GO:0017145 1 0.012
regulation of transporter activity GO:0032409 2 0.012
regulation of circadian rhythm GO:0042752 4 0.012
regulation of programmed cell death GO:0043067 101 0.012
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
calcium ion homeostasis GO:0055074 19 0.012
regulation of purine nucleotide metabolic process GO:1900542 17 0.012
regulation of protein targeting GO:1903533 2 0.012
lipid biosynthetic process GO:0008610 22 0.012
embryonic skeletal system development GO:0048706 97 0.012
ribonucleotide metabolic process GO:0009259 27 0.011
epithelial cell differentiation GO:0030855 116 0.011
Mouse
macromolecule modification GO:0043412 111 0.011
Mouse
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.011
negative regulation of catabolic process GO:0009895 3 0.011
regulation of receptor mediated endocytosis GO:0048259 4 0.011
meiosis ii GO:0007135 1 0.011
energy homeostasis GO:0097009 3 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
skeletal system morphogenesis GO:0048705 102 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
tissue regeneration GO:0042246 74 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
renal tubule morphogenesis GO:0061333 1 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
Mouse
regulation of growth rate GO:0040009 1 0.010
regulation of sodium ion transmembrane transport GO:1902305 1 0.010
lateral line development GO:0048882 66 0.010
cardiac conduction system development GO:0003161 1 0.010
response to nutrient GO:0007584 3 0.010
endocardium formation GO:0060214 1 0.010
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.010
cellular response to growth factor stimulus GO:0071363 39 0.010
vacuolar transport GO:0007034 2 0.010
heart morphogenesis GO:0003007 156 0.010

fshr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.147
lipid metabolism disorder DOID:3146 0 0.061
inherited metabolic disorder DOID:655 0 0.061
disease of anatomical entity DOID:7 0 0.016
Human
bone disease DOID:0080001 0 0.012
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
bone development disease DOID:0080006 0 0.011