Danio rerio

0 known processes

cx35.4

connexin 35.4

(Aliases: gjb3,zgc:112004,wu:fb02c04)

cx35.4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.071
organelle organization GO:0006996 227 0.066
Zebrafish
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.060
cellular component movement GO:0006928 335 0.059
alpha amino acid metabolic process GO:1901605 3 0.058
sensory system development GO:0048880 76 0.056
establishment of endothelial barrier GO:0061028 3 0.050
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.050
regulation of biological quality GO:0065008 263 0.049
regulation of sodium ion transport GO:0002028 2 0.049
cellular macromolecule metabolic process GO:0044260 391 0.044
morphogenesis of an epithelial sheet GO:0002011 49 0.040
membrane fusion GO:0061025 2 0.039
response to chemical GO:0042221 320 0.036
regulation of localization GO:0032879 104 0.036
Zebrafish
single organism membrane fusion GO:0044801 2 0.035
tube morphogenesis GO:0035239 349 0.034
gastrulation GO:0007369 208 0.034
lateral line system development GO:0048925 76 0.034
single organism organelle organization GO:1902589 199 0.033
Zebrafish
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.032
single fertilization GO:0007338 3 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
regulation of cytokine production GO:0001817 3 0.030
organic acid metabolic process GO:0006082 31 0.029
phagocytosis GO:0006909 3 0.029
digestive tract morphogenesis GO:0048546 231 0.028
epiboly GO:0090504 41 0.027
regulation of multicellular organismal process GO:0051239 277 0.026
regulation of protein transport GO:0051223 3 0.026
macromolecule biosynthetic process GO:0009059 227 0.026
g protein coupled receptor signaling pathway GO:0007186 74 0.026
stem cell maintenance GO:0019827 4 0.026
oxoacid metabolic process GO:0043436 31 0.026
negative regulation of cellular process GO:0048523 283 0.025
single organism localization GO:1902578 225 0.025
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.025
response to stress GO:0006950 263 0.024
Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.024
positive regulation of dna templated transcription elongation GO:0032786 1 0.024
regulation of metal ion transport GO:0010959 4 0.024
morphogenesis of an epithelium GO:0002009 333 0.023
positive regulation of transport GO:0051050 2 0.023
single organism metabolic process GO:0044710 217 0.023
positive regulation of cell cycle GO:0045787 3 0.022
actin filament based movement GO:0030048 1 0.022
cell morphogenesis GO:0000902 289 0.022
nitrogen compound metabolic process GO:0006807 319 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
desmosome organization GO:0002934 3 0.021
digestive tract development GO:0048565 265 0.021
organic acid catabolic process GO:0016054 3 0.021
aging GO:0007568 2 0.021
response to organic substance GO:0010033 153 0.021
meiotic nuclear division GO:0007126 4 0.020
brain development GO:0007420 293 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
regulation of protein complex assembly GO:0043254 3 0.019
system process GO:0003008 185 0.019
Zebrafish
cellular protein metabolic process GO:0044267 129 0.019
neuromast development GO:0048884 46 0.019
cellular response to starvation GO:0009267 1 0.018
protein metabolic process GO:0019538 183 0.018
fatty acid oxidation GO:0019395 1 0.018
cellular component biogenesis GO:0044085 178 0.018
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.017
regulation of cellular component organization GO:0051128 86 0.017
regulation of inflammatory response GO:0050727 2 0.017
rna biosynthetic process GO:0032774 181 0.017
dna templated transcription elongation GO:0006354 3 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.017
protein localization to plasma membrane GO:0072659 1 0.016
digestive system development GO:0055123 289 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
nuclear transport GO:0051169 4 0.016
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
regulation of biosynthetic process GO:0009889 250 0.016
regulation of muscle contraction GO:0006937 3 0.015
regulation of reproductive process GO:2000241 4 0.015
epidermis development GO:0008544 48 0.015
regulation of dna templated transcription in response to stress GO:0043620 0 0.015
determination of bilateral symmetry GO:0009855 204 0.015
rna metabolic process GO:0016070 219 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
Zebrafish
cell projection organization GO:0030030 284 0.015
regulation of primary metabolic process GO:0080090 311 0.015
response to wounding GO:0009611 116 0.015
Zebrafish
lipid catabolic process GO:0016042 4 0.015
positive regulation of cellular process GO:0048522 201 0.015
cytoskeleton organization GO:0007010 96 0.014
Zebrafish
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.014
transmission of nerve impulse GO:0019226 19 0.014
action potential GO:0001508 19 0.014
response to corticosteroid GO:0031960 1 0.014
rna localization GO:0006403 4 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
gastrulation with mouth forming second GO:0001702 44 0.014
nucleic acid metabolic process GO:0090304 244 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.014
regulation of cell activation GO:0050865 1 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
transport GO:0006810 220 0.013
Zebrafish
growth GO:0040007 174 0.013
Zebrafish
biosynthetic process GO:0009058 294 0.013
negative regulation of defense response GO:0031348 2 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
regulation of cellular component movement GO:0051270 55 0.013
response to organic cyclic compound GO:0014070 51 0.013
negative regulation of biological process GO:0048519 304 0.012
meiotic cell cycle process GO:1903046 3 0.012
regulation of locomotion GO:0040012 55 0.012
cellular protein modification process GO:0006464 100 0.012
regulation of macromolecule metabolic process GO:0060255 317 0.012
multicellular organismal signaling GO:0035637 22 0.012
immune system process GO:0002376 241 0.012
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
locomotion GO:0040011 313 0.012
regulation of circadian rhythm GO:0042752 4 0.012
membrane invagination GO:0010324 1 0.012
developmental growth GO:0048589 166 0.012
Zebrafish
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
negative regulation of cytokine production GO:0001818 1 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.011
specification of symmetry GO:0009799 204 0.011
neuroblast differentiation GO:0014016 1 0.011
peptide metabolic process GO:0006518 1 0.011
autophagy GO:0006914 4 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
anion transport GO:0006820 38 0.011
myeloid cell homeostasis GO:0002262 56 0.011
macromolecule localization GO:0033036 54 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
cell motility GO:0048870 244 0.011
negative regulation of rna splicing GO:0033119 1 0.011
cellular biosynthetic process GO:0044249 286 0.011
protein complex localization GO:0031503 1 0.011
zymogen activation GO:0031638 3 0.011
programmed cell death GO:0012501 119 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
maintenance of location GO:0051235 4 0.011
apical junction assembly GO:0043297 1 0.010
multicellular organism growth GO:0035264 4 0.010
regulation of programmed cell death GO:0043067 101 0.010
keratinocyte differentiation GO:0030216 0 0.010
nucleobase containing compound metabolic process GO:0006139 274 0.010
regulation of membrane potential GO:0042391 23 0.010
immune system development GO:0002520 191 0.010
Zebrafish
positive regulation of secretion GO:0051047 1 0.010
cellular macromolecule biosynthetic process GO:0034645 224 0.010
cellular amino acid metabolic process GO:0006520 7 0.010
larval development GO:0002164 2 0.010
negative regulation of gene expression GO:0010629 65 0.010
cellular component morphogenesis GO:0032989 336 0.010
Zebrafish
homeostatic process GO:0042592 142 0.010
mitochondrial transport GO:0006839 2 0.010

cx35.4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.014
muscular disease DOID:0080000 0 0.014
heart disease DOID:114 0 0.014
cardiomyopathy DOID:0050700 0 0.014
disease of anatomical entity DOID:7 0 0.014
cardiovascular system disease DOID:1287 0 0.014
musculoskeletal system disease DOID:17 0 0.014
muscle tissue disease DOID:66 0 0.014