Danio rerio

57 known processes

kcnh1

potassium voltage-gated channel, subfamily H (eag-related), member 1

kcnh1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transmembrane transport GO:0034762 18 0.399
chordate embryonic development GO:0043009 271 0.348
segmentation GO:0035282 97 0.270
regulation of ion transmembrane transport GO:0034765 18 0.252
response to transition metal nanoparticle GO:1990267 28 0.211
cation transmembrane transport GO:0098655 65 0.171
somite development GO:0061053 96 0.165
inorganic ion transmembrane transport GO:0098660 57 0.160
metal ion transport GO:0030001 58 0.151
single organism transport GO:0044765 206 0.147
cellular potassium ion transport GO:0071804 10 0.143
cation transport GO:0006812 81 0.138
inorganic cation transmembrane transport GO:0098662 50 0.120
cellular macromolecule metabolic process GO:0044260 391 0.117
embryo development ending in birth or egg hatching GO:0009792 271 0.104
regulation of localization GO:0032879 104 0.100
generation of neurons GO:0048699 385 0.097
monovalent inorganic cation transport GO:0015672 42 0.094
signal transduction GO:0007165 455 0.087
regionalization GO:0003002 274 0.083
transmembrane transport GO:0055085 120 0.076
blood vessel development GO:0001568 246 0.074
nitrogen compound metabolic process GO:0006807 319 0.070
morphogenesis of an epithelium GO:0002009 333 0.068
heterocycle biosynthetic process GO:0018130 215 0.067
hindbrain morphogenesis GO:0021575 22 0.064
cellular nitrogen compound metabolic process GO:0034641 290 0.063
central nervous system development GO:0007417 387 0.062
cellular macromolecule biosynthetic process GO:0034645 224 0.061
cellular response to dsrna GO:0071359 1 0.059
vasculature development GO:0001944 278 0.058
regulation of metabolic process GO:0019222 359 0.057
positive regulation of transport GO:0051050 2 0.056
gene expression GO:0010467 252 0.054
nucleic acid metabolic process GO:0090304 244 0.054
response to external stimulus GO:0009605 264 0.052
hindbrain development GO:0030902 91 0.052
protein localization to nucleus GO:0034504 3 0.051
autophagy GO:0006914 4 0.051
maintenance of location GO:0051235 4 0.051
rna metabolic process GO:0016070 219 0.050
regulation of wound healing GO:0061041 2 0.048
potassium ion transport GO:0006813 10 0.047
head development GO:0060322 303 0.047
cellular component morphogenesis GO:0032989 336 0.046
chemosensory behavior GO:0007635 1 0.043
organic cyclic compound metabolic process GO:1901360 301 0.043
tube morphogenesis GO:0035239 349 0.042
striated muscle tissue development GO:0014706 110 0.041
aging GO:0007568 2 0.040
regulation of protein transport GO:0051223 3 0.039
amine metabolic process GO:0009308 2 0.039
nucleobase containing compound metabolic process GO:0006139 274 0.039
cellular nitrogen compound biosynthetic process GO:0044271 218 0.039
determination of bilateral symmetry GO:0009855 204 0.039
cognition GO:0050890 1 0.039
establishment of localization GO:0051234 244 0.038
heterocycle metabolic process GO:0046483 290 0.037
biosynthetic process GO:0009058 294 0.037
organic substance biosynthetic process GO:1901576 289 0.036
negative regulation of biological process GO:0048519 304 0.036
specification of symmetry GO:0009799 204 0.036
transport GO:0006810 220 0.036
single organism localization GO:1902578 225 0.036
sequestering of metal ion GO:0051238 3 0.035
response to stress GO:0006950 263 0.033
determination of heart left right asymmetry GO:0061371 117 0.033
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.033
cellular amine metabolic process GO:0044106 2 0.032
sensory organ development GO:0007423 393 0.032
regulation of cellular metabolic process GO:0031323 320 0.031
digestive tract morphogenesis GO:0048546 231 0.031
g protein coupled receptor signaling pathway GO:0007186 74 0.030
regulation of response to stimulus GO:0048583 269 0.030
anterior posterior pattern specification GO:0009952 152 0.030
regulation of macromolecule metabolic process GO:0060255 317 0.030
determination of left right symmetry GO:0007368 179 0.030
sprouting angiogenesis GO:0002040 53 0.030
aromatic compound biosynthetic process GO:0019438 217 0.030
heart looping GO:0001947 94 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.029
larval development GO:0002164 2 0.029
cellular aromatic compound metabolic process GO:0006725 295 0.029
eye development GO:0001654 277 0.029
gtp metabolic process GO:0046039 4 0.028
single organism metabolic process GO:0044710 217 0.028
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
muscle organ development GO:0007517 101 0.028
response to vitamin GO:0033273 3 0.028
meiotic nuclear division GO:0007126 4 0.028
regulation of mrna splicing via spliceosome GO:0048024 3 0.028
nucleocytoplasmic transport GO:0006913 4 0.027
regulation of transcription dna templated GO:0006355 213 0.027
homeostatic process GO:0042592 142 0.027
cellular biosynthetic process GO:0044249 286 0.026
heart development GO:0007507 313 0.026
germ line stem cell maintenance GO:0030718 2 0.026
system process GO:0003008 185 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
regulation of cell communication GO:0010646 232 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
lipid storage GO:0019915 1 0.026
adult behavior GO:0030534 2 0.026
modification dependent protein catabolic process GO:0019941 3 0.026
regulation of biological quality GO:0065008 263 0.026
neural retina development GO:0003407 49 0.026
rna biosynthetic process GO:0032774 181 0.025
regulation of metal ion transport GO:0010959 4 0.025
b cell differentiation GO:0030183 1 0.025
muscle structure development GO:0061061 196 0.025
sensory system development GO:0048880 76 0.025
response to chemical GO:0042221 320 0.025
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.025
epithelial tube morphogenesis GO:0060562 148 0.025
microtubule organizing center organization GO:0031023 1 0.025
regulation of cytoplasmic transport GO:1903649 4 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
ameboidal type cell migration GO:0001667 143 0.024
locomotion GO:0040011 313 0.024
reactive oxygen species biosynthetic process GO:1903409 1 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
cell morphogenesis GO:0000902 289 0.024
response to nutrient GO:0007584 3 0.024
regulation of sodium ion transport GO:0002028 2 0.024
retina development in camera type eye GO:0060041 146 0.024
negative regulation of protein kinase activity GO:0006469 4 0.024
gtp catabolic process GO:0006184 2 0.024
zinc ion transmembrane transport GO:0071577 1 0.023
behavior GO:0007610 74 0.023
nucleic acid templated transcription GO:0097659 181 0.023
cellular component biogenesis GO:0044085 178 0.023
regulation of reactive oxygen species metabolic process GO:2000377 2 0.023
cellular component movement GO:0006928 335 0.023
multicellular organism growth GO:0035264 4 0.023
zinc ion transport GO:0006829 2 0.023
nuclear transport GO:0051169 4 0.023
skeletal muscle organ development GO:0060538 78 0.022
regulation of calcium ion transport GO:0051924 2 0.022
regulation of gene expression GO:0010468 265 0.022
cell surface receptor signaling pathway GO:0007166 325 0.022
negative regulation of kinase activity GO:0033673 4 0.022
regulation of primary metabolic process GO:0080090 311 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
nitric oxide metabolic process GO:0046209 2 0.022
nitric oxide biosynthetic process GO:0006809 2 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.021
blood vessel morphogenesis GO:0048514 216 0.021
stem cell maintenance GO:0019827 4 0.021
regulation of reproductive process GO:2000241 4 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
endosomal transport GO:0016197 2 0.021
camera type eye development GO:0043010 222 0.021
ion transmembrane transport GO:0034220 91 0.021
ion transport GO:0006811 114 0.021
potassium ion transmembrane transport GO:0071805 10 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
embryonic heart tube development GO:0035050 133 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
digestive system development GO:0055123 289 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
transcription dna templated GO:0006351 181 0.020
cell projection organization GO:0030030 284 0.020
positive regulation of myeloid cell differentiation GO:0045639 2 0.020
positive regulation of wound healing GO:0090303 1 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
regulation of autophagy GO:0010506 3 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
stem cell division GO:0017145 1 0.020
negative regulation of cellular process GO:0048523 283 0.019
regulation of rna metabolic process GO:0051252 224 0.019
stem cell proliferation GO:0072089 4 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
nuclear import GO:0051170 3 0.019
urogenital system development GO:0001655 97 0.019
heart morphogenesis GO:0003007 156 0.019
regulation of protein binding GO:0043393 3 0.019
angiogenesis GO:0001525 158 0.019
ovulation cycle process GO:0022602 2 0.019
adherens junction organization GO:0034332 4 0.018
mitochondrion organization GO:0007005 4 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
wound healing GO:0042060 90 0.018
neuron development GO:0048666 262 0.018
negative regulation of translation GO:0017148 1 0.018
protein metabolic process GO:0019538 183 0.018
regulation of transporter activity GO:0032409 2 0.018
regulation of signal transduction GO:0009966 225 0.018
muscle tissue development GO:0060537 110 0.018
cell motility GO:0048870 244 0.018
lipid catabolic process GO:0016042 4 0.018
ribosomal small subunit biogenesis GO:0042274 2 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.017
ovulation cycle GO:0042698 2 0.017
centrosome cycle GO:0007098 1 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
mesenchyme development GO:0060485 127 0.016
negative regulation of gene expression GO:0010629 65 0.016
cell part morphogenesis GO:0032990 246 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
peptide transport GO:0015833 1 0.016
cellular response to external stimulus GO:0071496 2 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
phagocytosis GO:0006909 3 0.016
tissue migration GO:0090130 37 0.016
mechanosensory behavior GO:0007638 2 0.016
negative regulation of protein transport GO:0051224 3 0.016
rna localization GO:0006403 4 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
photoreceptor cell differentiation GO:0046530 55 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
positive regulation of epithelial cell migration GO:0010634 2 0.016
positive regulation of signal transduction GO:0009967 56 0.016
pancreas development GO:0031016 84 0.016
cranial nerve development GO:0021545 42 0.015
regulation of blood vessel size GO:0050880 2 0.015
female sex differentiation GO:0046660 4 0.015
protein import GO:0017038 3 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
lipid homeostasis GO:0055088 3 0.015
embryonic organ development GO:0048568 381 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.015
regulation of signaling GO:0023051 235 0.015
retina morphogenesis in camera type eye GO:0060042 79 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
retina layer formation GO:0010842 24 0.015
rna processing GO:0006396 25 0.015
regulation of blood coagulation GO:0030193 1 0.015
regulation of protein targeting GO:1903533 2 0.015
regulation of mrna processing GO:0050684 3 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
periodic partitioning GO:0007365 1 0.015
regulation of organelle assembly GO:1902115 4 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
positive regulation of biological process GO:0048518 253 0.014
regulation of endothelial cell proliferation GO:0001936 1 0.014
cellular component assembly GO:0022607 170 0.014
striated muscle cell differentiation GO:0051146 129 0.014
regulation of protein complex assembly GO:0043254 3 0.014
regulation of neurological system process GO:0031644 2 0.014
positive regulation of inflammatory response GO:0050729 1 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
translational initiation GO:0006413 3 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
skeletal muscle tissue development GO:0007519 67 0.014
somitogenesis GO:0001756 87 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
response to organic substance GO:0010033 153 0.013
neuron differentiation GO:0030182 353 0.013
camera type eye morphogenesis GO:0048593 108 0.013
regulation of translational initiation GO:0006446 1 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
cellular ketone metabolic process GO:0042180 11 0.013
neurological system process GO:0050877 62 0.013
protein targeting to nucleus GO:0044744 3 0.013
glucose homeostasis GO:0042593 1 0.013
digestive tract development GO:0048565 265 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of gtpase activity GO:0043087 2 0.013
cellular transition metal ion homeostasis GO:0046916 3 0.013
gastrulation GO:0007369 208 0.013
meiotic cell cycle process GO:1903046 3 0.013
negative regulation of protein complex assembly GO:0031333 1 0.012
striated muscle cell development GO:0055002 108 0.012
cell migration involved in gastrulation GO:0042074 79 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
cellular response to starvation GO:0009267 1 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
membrane fusion GO:0061025 2 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
b cell activation GO:0042113 2 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
response to cold GO:0009409 4 0.012
peptidyl serine modification GO:0018209 2 0.012
adherens junction assembly GO:0034333 1 0.012
positive regulation of cell cycle GO:0045787 3 0.012
cell substrate adhesion GO:0031589 4 0.012
ovarian follicle development GO:0001541 2 0.012
synapsis GO:0007129 1 0.012
cell volume homeostasis GO:0006884 1 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
kidney development GO:0001822 92 0.012
mrna cleavage involved in gene silencing by mirna GO:0035279 1 0.012
regulation of cell activation GO:0050865 1 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
protein homooligomerization GO:0051260 3 0.011
intracellular signal transduction GO:0035556 85 0.011
regulation of binding GO:0051098 3 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
protein modification process GO:0036211 100 0.011
sensory perception of pain GO:0019233 1 0.011
small molecule metabolic process GO:0044281 77 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
eye morphogenesis GO:0048592 144 0.011
smooth muscle contraction GO:0006939 2 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
p38mapk cascade GO:0038066 1 0.011
defense response to bacterium GO:0042742 22 0.011
cell migration GO:0016477 237 0.011
notochord development GO:0030903 54 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
secondary metabolic process GO:0019748 3 0.011
cell projection morphogenesis GO:0048858 244 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
female gonad development GO:0008585 4 0.011
regulation of cell motility GO:2000145 46 0.011
sensory organ morphogenesis GO:0090596 200 0.011
heart contraction GO:0060047 71 0.011
dna catabolic process GO:0006308 1 0.011
regulation of tube size GO:0035150 2 0.011
spermatid development GO:0007286 2 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
negative regulation of mrna metabolic process GO:1903312 3 0.011
regulation of developmental process GO:0050793 247 0.011
catecholamine metabolic process GO:0006584 2 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
macromolecule modification GO:0043412 111 0.011
hemopoiesis GO:0030097 183 0.011
cellular protein metabolic process GO:0044267 129 0.010
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.010
erk1 and erk2 cascade GO:0070371 4 0.010
cellular protein modification process GO:0006464 100 0.010
regulation of synapse assembly GO:0051963 3 0.010
thermosensory behavior GO:0040040 1 0.010
modification dependent macromolecule catabolic process GO:0043632 3 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
regulation of cell projection assembly GO:0060491 4 0.010
centrosome duplication GO:0051298 1 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
protein polymerization GO:0051258 4 0.010
positive regulation of secretion GO:0051047 1 0.010
cilium organization GO:0044782 71 0.010
muscle cell development GO:0055001 115 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
regulation of intracellular ph GO:0051453 1 0.010

kcnh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.110
immune system disease DOID:2914 0 0.086
bone marrow disease DOID:4961 0 0.086
hematopoietic system disease DOID:74 0 0.086
anemia DOID:2355 0 0.034
aplastic anemia DOID:12449 0 0.023
congenital hypoplastic anemia DOID:1342 0 0.022
fanconi s anemia DOID:13636 0 0.022
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
nervous system disease DOID:863 0 0.018
eye disease DOID:5614 0 0.018
organ system cancer DOID:0050686 0 0.018
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.013