Danio rerio

0 known processes

lrrc3

leucine rich repeat containing 3

(Aliases: si:dkey-253a1.3,sc:d0333)

lrrc3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.135
cell projection morphogenesis GO:0048858 244 0.063
positive regulation of transport GO:0051050 2 0.060
head development GO:0060322 303 0.054
phagocytosis GO:0006909 3 0.049
single organism localization GO:1902578 225 0.047
aging GO:0007568 2 0.047
brain development GO:0007420 293 0.047
organic substance biosynthetic process GO:1901576 289 0.047
aromatic compound biosynthetic process GO:0019438 217 0.047
cellular component morphogenesis GO:0032989 336 0.046
cellular nitrogen compound metabolic process GO:0034641 290 0.046
nitrogen compound metabolic process GO:0006807 319 0.045
neurotransmitter transport GO:0006836 2 0.045
transport GO:0006810 220 0.042
cellular biosynthetic process GO:0044249 286 0.041
regulation of metabolic process GO:0019222 359 0.040
heart development GO:0007507 313 0.040
establishment of localization GO:0051234 244 0.040
rna metabolic process GO:0016070 219 0.038
regulation of response to stimulus GO:0048583 269 0.038
regulation of circadian rhythm GO:0042752 4 0.038
neuron development GO:0048666 262 0.037
regulation of multicellular organism growth GO:0040014 4 0.037
organic cyclic compound biosynthetic process GO:1901362 223 0.037
cell part morphogenesis GO:0032990 246 0.037
organic cyclic compound metabolic process GO:1901360 301 0.036
embryonic organ development GO:0048568 381 0.035
central nervous system development GO:0007417 387 0.035
generation of neurons GO:0048699 385 0.035
biosynthetic process GO:0009058 294 0.034
nuclear transport GO:0051169 4 0.034
regulation of cellular amine metabolic process GO:0033238 0 0.034
heterocycle metabolic process GO:0046483 290 0.034
nucleobase containing compound biosynthetic process GO:0034654 205 0.034
regulation of cellular biosynthetic process GO:0031326 245 0.033
response to chemical GO:0042221 320 0.033
heterocycle biosynthetic process GO:0018130 215 0.032
adult behavior GO:0030534 2 0.032
establishment of protein localization to organelle GO:0072594 4 0.032
cellular nitrogen compound biosynthetic process GO:0044271 218 0.032
gene expression GO:0010467 252 0.031
regulation of nitrogen compound metabolic process GO:0051171 251 0.031
rna biosynthetic process GO:0032774 181 0.031
regulation of primary metabolic process GO:0080090 311 0.031
positive regulation of biological process GO:0048518 253 0.031
sensory organ development GO:0007423 393 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.030
neuron differentiation GO:0030182 353 0.030
protein localization to nucleus GO:0034504 3 0.030
signal transduction GO:0007165 455 0.029
cell projection organization GO:0030030 284 0.029
cellular macromolecule biosynthetic process GO:0034645 224 0.029
nucleocytoplasmic transport GO:0006913 4 0.029
amine metabolic process GO:0009308 2 0.029
regulation of macromolecule biosynthetic process GO:0010556 225 0.029
regulation of gene expression GO:0010468 265 0.029
multicellular organism growth GO:0035264 4 0.028
cellular amine metabolic process GO:0044106 2 0.028
single organism transport GO:0044765 206 0.028
regulation of meiotic cell cycle GO:0051445 1 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.028
regulation of multicellular organismal process GO:0051239 277 0.028
regulation of rna biosynthetic process GO:2001141 213 0.028
cell migration GO:0016477 237 0.027
response to external stimulus GO:0009605 264 0.027
chemosensory behavior GO:0007635 1 0.027
regulation of transcription dna templated GO:0006355 213 0.027
meiotic nuclear division GO:0007126 4 0.027
lipid catabolic process GO:0016042 4 0.027
neuron neuron synaptic transmission GO:0007270 1 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
cell morphogenesis GO:0000902 289 0.026
cellular ketone metabolic process GO:0042180 11 0.026
cell surface receptor signaling pathway GO:0007166 325 0.026
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
immune system process GO:0002376 241 0.026
camera type eye development GO:0043010 222 0.026
determination of bilateral symmetry GO:0009855 204 0.026
cognition GO:0050890 1 0.026
organic acid metabolic process GO:0006082 31 0.025
stem cell proliferation GO:0072089 4 0.025
maintenance of location GO:0051235 4 0.025
organelle organization GO:0006996 227 0.025
sleep GO:0030431 1 0.025
determination of left right symmetry GO:0007368 179 0.025
positive regulation of cellular process GO:0048522 201 0.025
positive regulation of secretion by cell GO:1903532 1 0.024
regulation of signal transduction GO:0009966 225 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.024
locomotion GO:0040011 313 0.024
regulation of rna metabolic process GO:0051252 224 0.024
female sex differentiation GO:0046660 4 0.024
neurotransmitter secretion GO:0007269 2 0.024
phagocytosis engulfment GO:0006911 1 0.024
regulation of synapse organization GO:0050807 3 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
gtp catabolic process GO:0006184 2 0.023
axon development GO:0061564 166 0.023
regulation of reproductive process GO:2000241 4 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
vasculature development GO:0001944 278 0.023
oxoacid metabolic process GO:0043436 31 0.023
transcription dna templated GO:0006351 181 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
regulation of biosynthetic process GO:0009889 250 0.023
cell motility GO:0048870 244 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
regulation of protein transport GO:0051223 3 0.023
cellular component movement GO:0006928 335 0.022
regulation of blood pressure GO:0008217 1 0.022
organelle assembly GO:0070925 110 0.022
single organism nuclear import GO:1902593 3 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
nucleic acid templated transcription GO:0097659 181 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
protein import GO:0017038 3 0.022
cellular amide metabolic process GO:0043603 4 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
system process GO:0003008 185 0.022
neuron projection morphogenesis GO:0048812 161 0.022
protein targeting to nucleus GO:0044744 3 0.022
regulation of biological quality GO:0065008 263 0.021
negative regulation of biological process GO:0048519 304 0.021
transmembrane transport GO:0055085 120 0.021
positive regulation of cell cycle GO:0045787 3 0.021
positive regulation of immune effector process GO:0002699 3 0.021
response to stress GO:0006950 263 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
nucleic acid metabolic process GO:0090304 244 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.021
cell morphogenesis involved in differentiation GO:0000904 195 0.021
single organism metabolic process GO:0044710 217 0.021
regulation of synapse assembly GO:0051963 3 0.021
gtp metabolic process GO:0046039 4 0.021
protein import into nucleus GO:0006606 3 0.021
regulation of metal ion transport GO:0010959 4 0.021
cellular protein metabolic process GO:0044267 129 0.021
cellular localization GO:0051641 97 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.020
cellular component biogenesis GO:0044085 178 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
nuclear import GO:0051170 3 0.020
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
morphogenesis of an epithelium GO:0002009 333 0.020
blood vessel development GO:0001568 246 0.020
axonogenesis GO:0007409 152 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
stem cell maintenance GO:0019827 4 0.020
positive regulation of catabolic process GO:0009896 4 0.020
cellular component assembly involved in morphogenesis GO:0010927 107 0.020
specification of symmetry GO:0009799 204 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.020
multicellular organismal response to stress GO:0033555 2 0.019
regulation of blood vessel size GO:0050880 2 0.019
regulation of cytokine production GO:0001817 3 0.019
tube morphogenesis GO:0035239 349 0.019
cilium morphogenesis GO:0060271 85 0.019
single organism organelle organization GO:1902589 199 0.019
regulation of protein import into nucleus GO:0042306 2 0.019
positive regulation of secretion GO:0051047 1 0.019
eye development GO:0001654 277 0.019
sensory perception of chemical stimulus GO:0007606 3 0.019
regulation of transporter activity GO:0032409 2 0.019
regulation of neurotransmitter secretion GO:0046928 1 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
regulation of signaling GO:0023051 235 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
synaptic vesicle localization GO:0097479 1 0.019
protein acetylation GO:0006473 2 0.019
lipid storage GO:0019915 1 0.019
regulation of mrna processing GO:0050684 3 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
pancreas development GO:0031016 84 0.018
membrane invagination GO:0010324 1 0.018
negative regulation of signal transduction GO:0009968 94 0.018
digestive tract development GO:0048565 265 0.018
protein metabolic process GO:0019538 183 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
establishment of localization in cell GO:0051649 77 0.018
response to organic substance GO:0010033 153 0.018
regulation of transmembrane transporter activity GO:0022898 2 0.018
ion transmembrane transport GO:0034220 91 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.018
regulation of cell activation GO:0050865 1 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
regulation of ion transmembrane transporter activity GO:0032412 2 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
organelle localization GO:0051640 49 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
spermatid differentiation GO:0048515 2 0.017
digestive system development GO:0055123 289 0.017
regulation of cell communication GO:0010646 232 0.017
cellular response to external stimulus GO:0071496 2 0.017
hemopoiesis GO:0030097 183 0.017
hormone secretion GO:0046879 2 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
regulation of developmental process GO:0050793 247 0.017
regulation of tube size GO:0035150 2 0.017
hormone transport GO:0009914 2 0.017
cilium organization GO:0044782 71 0.017
response to food GO:0032094 1 0.017
endocrine system development GO:0035270 65 0.017
peptide transport GO:0015833 1 0.017
response to hexose GO:0009746 3 0.017
synaptic vesicle transport GO:0048489 1 0.017
mononuclear cell proliferation GO:0032943 1 0.017
amino acid transport GO:0006865 2 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
exocytosis GO:0006887 1 0.016
action potential GO:0001508 19 0.016
peptidyl serine modification GO:0018209 2 0.016
regionalization GO:0003002 274 0.016
neuroblast proliferation GO:0007405 2 0.016
secondary metabolic process GO:0019748 3 0.016
central nervous system neuron differentiation GO:0021953 74 0.016
sensory organ morphogenesis GO:0090596 200 0.016
fertilization GO:0009566 3 0.016
retina development in camera type eye GO:0060041 146 0.016
muscle structure development GO:0061061 196 0.016
response to monosaccharide GO:0034284 3 0.016
regulation of cell shape GO:0008360 1 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of response to biotic stimulus GO:0002831 2 0.016
macromolecular complex disassembly GO:0032984 1 0.016
establishment of synaptic vesicle localization GO:0097480 1 0.016
small molecule metabolic process GO:0044281 77 0.016
lymphocyte proliferation GO:0046651 1 0.016
regulation of striated muscle contraction GO:0006942 2 0.016
localization of cell GO:0051674 244 0.016
regulation of neurotransmitter transport GO:0051588 1 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
small molecule catabolic process GO:0044282 3 0.015
interspecies interaction between organisms GO:0044419 4 0.015
glucose homeostasis GO:0042593 1 0.015
regulation of inflammatory response GO:0050727 2 0.015
protein acylation GO:0043543 3 0.015
female gonad development GO:0008585 4 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
negative regulation of kinase activity GO:0033673 4 0.015
response to drug GO:0042493 3 0.015
cell differentiation in spinal cord GO:0021515 40 0.015
regulation of protein complex assembly GO:0043254 3 0.015
cellular response to nutrient levels GO:0031669 2 0.015
regulation of hormone secretion GO:0046883 2 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
protein complex disassembly GO:0043241 1 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
circadian sleep wake cycle sleep GO:0050802 1 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
positive regulation of cell activation GO:0050867 1 0.015
negative regulation of cellular process GO:0048523 283 0.015
positive regulation of metabolic process GO:0009893 108 0.015
cellular component disassembly GO:0022411 1 0.014
leukocyte proliferation GO:0070661 1 0.014
spinal cord development GO:0021510 46 0.014
cell substrate adhesion GO:0031589 4 0.014
spermatid development GO:0007286 2 0.014
cation transmembrane transport GO:0098655 65 0.014
startle response GO:0001964 4 0.014
neurological system process GO:0050877 62 0.014
cellular component assembly GO:0022607 170 0.014
actin filament based movement GO:0030048 1 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
response to carbohydrate GO:0009743 3 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
digestive tract morphogenesis GO:0048546 231 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
fin development GO:0033333 77 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
neuron projection development GO:0031175 180 0.014
response to alkaloid GO:0043279 2 0.014
homeostatic process GO:0042592 142 0.014
negative regulation of cell communication GO:0010648 96 0.014
carbohydrate homeostasis GO:0033500 1 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
blood vessel morphogenesis GO:0048514 216 0.013
compound eye development GO:0048749 2 0.013
negative regulation of protein transport GO:0051224 3 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
chemotaxis GO:0006935 104 0.013
regulation of glial cell differentiation GO:0045685 4 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
establishment of organelle localization GO:0051656 45 0.013
negative regulation of gliogenesis GO:0014014 1 0.013
cytokinesis GO:0000910 3 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
chordate embryonic development GO:0043009 271 0.013
anterior posterior pattern specification GO:0009952 152 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
glial cell migration GO:0008347 3 0.013
inorganic ion transmembrane transport GO:0098660 57 0.013
regulation of circadian sleep wake cycle GO:0042749 1 0.013
eye morphogenesis GO:0048592 144 0.013
endocrine pancreas development GO:0031018 27 0.013
alternative mrna splicing via spliceosome GO:0000380 1 0.013
circadian sleep wake cycle process GO:0022410 2 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
striated muscle cell differentiation GO:0051146 129 0.013
golgi vesicle transport GO:0048193 3 0.013
nuclear export GO:0051168 1 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
taxis GO:0042330 109 0.013
response to amphetamine GO:0001975 1 0.013
multi organism cellular process GO:0044764 2 0.013
gastrulation GO:0007369 208 0.012
macromolecule modification GO:0043412 111 0.012
cellular response to starvation GO:0009267 1 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
cell matrix adhesion GO:0007160 4 0.012
organic substance transport GO:0071702 58 0.012
immune system development GO:0002520 191 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
axon guidance GO:0007411 86 0.012
regulation of cell differentiation GO:0045595 142 0.012
ion transport GO:0006811 114 0.012
dicarboxylic acid transport GO:0006835 1 0.012
positive regulation of cytokine production GO:0001819 2 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
growth GO:0040007 174 0.012
dopamine metabolic process GO:0042417 2 0.012
angiogenesis GO:0001525 158 0.012
multi organism process GO:0051704 134 0.012
single fertilization GO:0007338 3 0.012
atp catabolic process GO:0006200 4 0.012
sequestering of metal ion GO:0051238 3 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
regulation of protein targeting GO:1903533 2 0.012
response to glucose GO:0009749 3 0.012
synaptic vesicle endocytosis GO:0048488 1 0.012
ventral spinal cord development GO:0021517 35 0.012
regulation of gtpase activity GO:0043087 2 0.012
protein secretion GO:0009306 1 0.012
antimicrobial humoral response GO:0019730 2 0.012
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
response to amine GO:0014075 1 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
rna localization GO:0006403 4 0.012
axon ensheathment in central nervous system GO:0032291 2 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
cellular response to organic substance GO:0071310 105 0.012
muscle cell differentiation GO:0042692 139 0.012
protein stabilization GO:0050821 2 0.012
cilium assembly GO:0042384 58 0.011
circadian sleep wake cycle GO:0042745 2 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
hatching GO:0035188 4 0.011
meiotic cell cycle process GO:1903046 3 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
heart looping GO:0001947 94 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
membrane fusion GO:0061025 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
transmission of nerve impulse GO:0019226 19 0.011
sensory system development GO:0048880 76 0.011
somite development GO:0061053 96 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
embryonic skeletal system development GO:0048706 97 0.011
ear development GO:0043583 127 0.011
epithelial cell differentiation GO:0030855 116 0.011
regulation of calcium ion transport GO:0051924 2 0.011
lateral line system development GO:0048925 76 0.011
regulation of myotube differentiation GO:0010830 2 0.011
muscle cell development GO:0055001 115 0.011
embryonic heart tube development GO:0035050 133 0.011
locomotor rhythm GO:0045475 3 0.011
myofibril assembly GO:0030239 48 0.011
regulation of cellular component organization GO:0051128 86 0.011
spindle assembly GO:0051225 2 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
inner ear development GO:0048839 126 0.011
striated muscle tissue development GO:0014706 110 0.011
response to hydrogen peroxide GO:0042542 3 0.011
mitochondrion organization GO:0007005 4 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
regulation of exocytosis GO:0017157 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
cytoskeleton organization GO:0007010 96 0.011
protein homooligomerization GO:0051260 3 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
regulation of dendrite development GO:0050773 3 0.010
immunoglobulin mediated immune response GO:0016064 3 0.010
cellular lipid catabolic process GO:0044242 3 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
negative regulation of secretion GO:0051048 2 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010
apoptotic process GO:0006915 116 0.010
cytoplasm organization GO:0007028 4 0.010
liver development GO:0001889 96 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
b cell activation GO:0042113 2 0.010
protein polymerization GO:0051258 4 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
thermosensory behavior GO:0040040 1 0.010
protein localization to plasma membrane GO:0072659 1 0.010
regulation of membrane potential GO:0042391 23 0.010
peptide metabolic process GO:0006518 1 0.010
somatic muscle development GO:0007525 4 0.010
regulation of protein polymerization GO:0032271 2 0.010
positive regulation of gene expression GO:0010628 71 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
autophagy GO:0006914 4 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
regulation of muscle contraction GO:0006937 3 0.010

lrrc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
musculoskeletal system disease DOID:17 0 0.014
nervous system disease DOID:863 0 0.013
disease of metabolism DOID:0014667 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
cardiovascular system disease DOID:1287 0 0.012