Danio rerio

0 known processes

nenf

neuron derived neurotrophic factor

(Aliases: zgc:152703,wu:fa11a04,wu:fb73f07,sp2,zgc:112953,MGC152703,MGC112953)

nenf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 181 0.080
aging GO:0007568 2 0.076
nucleic acid templated transcription GO:0097659 181 0.047
peptide transport GO:0015833 1 0.047
regulation of rna biosynthetic process GO:2001141 213 0.046
regulation of nucleic acid templated transcription GO:1903506 213 0.044
cellular response to lipopolysaccharide GO:0071222 3 0.042
regulation of rna metabolic process GO:0051252 224 0.042
positive regulation of catabolic process GO:0009896 4 0.041
rna metabolic process GO:0016070 219 0.041
maintenance of location GO:0051235 4 0.039
macromolecule biosynthetic process GO:0009059 227 0.038
regulation of multicellular organismal process GO:0051239 277 0.038
brain development GO:0007420 293 0.037
cell projection organization GO:0030030 284 0.037
regulation of cytokine production GO:0001817 3 0.037
regulation of macromolecule biosynthetic process GO:0010556 225 0.036
single organism transport GO:0044765 206 0.035
nucleobase containing compound metabolic process GO:0006139 274 0.035
cellular response to molecule of bacterial origin GO:0071219 3 0.035
response to chemical GO:0042221 320 0.034
organic cyclic compound biosynthetic process GO:1901362 223 0.034
cellular response to nutrient levels GO:0031669 2 0.034
regulation of response to stimulus GO:0048583 269 0.033
Mouse
cellular component morphogenesis GO:0032989 336 0.033
embryonic organ development GO:0048568 381 0.033
hormone transport GO:0009914 2 0.033
single organism localization GO:1902578 225 0.032
establishment of synaptic vesicle localization GO:0097480 1 0.032
positive regulation of cellular catabolic process GO:0031331 3 0.032
negative regulation of protein localization to nucleus GO:1900181 2 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
regulation of signaling GO:0023051 235 0.031
Mouse
larval development GO:0002164 2 0.031
hormone secretion GO:0046879 2 0.031
regulation of protein complex assembly GO:0043254 3 0.030
lipid storage GO:0019915 1 0.030
defense response GO:0006952 47 0.030
cell morphogenesis GO:0000902 289 0.029
localization of cell GO:0051674 244 0.029
cell projection morphogenesis GO:0048858 244 0.029
gtp metabolic process GO:0046039 4 0.029
guanosine containing compound metabolic process GO:1901068 4 0.028
cilium morphogenesis GO:0060271 85 0.028
regulation of transcription dna templated GO:0006355 213 0.027
negative regulation of cellular process GO:0048523 283 0.027
regulation of binding GO:0051098 3 0.027
organic substance biosynthetic process GO:1901576 289 0.027
heterocycle metabolic process GO:0046483 290 0.027
single organism metabolic process GO:0044710 217 0.027
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
immune system process GO:0002376 241 0.027
regulation of protein transport GO:0051223 3 0.026
cellular macromolecule metabolic process GO:0044260 391 0.026
cellular nitrogen compound biosynthetic process GO:0044271 218 0.026
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.026
cellular response to external stimulus GO:0071496 2 0.026
protein targeting to nucleus GO:0044744 3 0.026
biosynthetic process GO:0009058 294 0.025
rna biosynthetic process GO:0032774 181 0.025
response to nutrient GO:0007584 3 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
protein import into nucleus GO:0006606 3 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.024
vacuolar transport GO:0007034 2 0.024
protein import GO:0017038 3 0.024
response to organic substance GO:0010033 153 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
cellular component assembly involved in morphogenesis GO:0010927 107 0.023
regulation of gtpase activity GO:0043087 2 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
single organism nuclear import GO:1902593 3 0.023
regulation of protein catabolic process GO:0042176 1 0.023
nucleic acid metabolic process GO:0090304 244 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
regulation of protein import into nucleus GO:0042306 2 0.023
negative regulation of biological process GO:0048519 304 0.023
head development GO:0060322 303 0.023
nuclear import GO:0051170 3 0.022
positive regulation of reproductive process GO:2000243 2 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
regulation of protein targeting GO:1903533 2 0.022
endosomal transport GO:0016197 2 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
regulation of protein localization to nucleus GO:1900180 2 0.022
internal protein amino acid acetylation GO:0006475 2 0.022
sequestering of calcium ion GO:0051208 3 0.022
regulation of gtp catabolic process GO:0033124 2 0.022
exocytosis GO:0006887 1 0.022
cellular response to starvation GO:0009267 1 0.022
synaptic vesicle transport GO:0048489 1 0.021
establishment of localization GO:0051234 244 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
negative regulation of protein transport GO:0051224 3 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
positive regulation of cellular process GO:0048522 201 0.021
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.021
regulation of signal transduction GO:0009966 225 0.020
Mouse
organelle fusion GO:0048284 3 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
cellular biosynthetic process GO:0044249 286 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
protein localization to nucleus GO:0034504 3 0.020
positive regulation of secretion by cell GO:1903532 1 0.020
cellular component assembly GO:0022607 170 0.019
regulation of cellular metabolic process GO:0031323 320 0.019
Mouse
secondary metabolic process GO:0019748 3 0.019
developmental growth involved in morphogenesis GO:0060560 86 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
organic acid metabolic process GO:0006082 31 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
regulation of localization GO:0032879 104 0.019
cellular localization GO:0051641 97 0.019
regulation of synaptic vesicle transport GO:1902803 1 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
cellular amide metabolic process GO:0043603 4 0.019
positive regulation of transport GO:0051050 2 0.019
cellular response to biotic stimulus GO:0071216 3 0.019
regulation of nucleotide catabolic process GO:0030811 2 0.018
striated muscle cell differentiation GO:0051146 129 0.018
neurotransmitter transport GO:0006836 2 0.018
locomotion GO:0040011 313 0.018
calcium ion transport into cytosol GO:0060402 3 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
negative regulation of cytoplasmic transport GO:1903650 2 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
lytic vacuole organization GO:0080171 1 0.017
regulation of biosynthetic process GO:0009889 250 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
response to xenobiotic stimulus GO:0009410 45 0.017
regulation of intracellular ph GO:0051453 1 0.017
regulation of blood pressure GO:0008217 1 0.017
regulation of primary metabolic process GO:0080090 311 0.017
positive regulation of camp biosynthetic process GO:0030819 2 0.017
response to drug GO:0042493 3 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
regulation of hormone secretion GO:0046883 2 0.016
mitochondrion organization GO:0007005 4 0.016
nuclear transport GO:0051169 4 0.016
transport GO:0006810 220 0.016
sensory perception of chemical stimulus GO:0007606 3 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
cellular response to lipid GO:0071396 39 0.016
viral process GO:0016032 1 0.016
sequestering of metal ion GO:0051238 3 0.016
regulation of blood vessel size GO:0050880 2 0.016
membrane fusion GO:0061025 2 0.016
positive regulation of gtpase activity GO:0043547 1 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
innate immune response GO:0045087 13 0.015
negative regulation of nuclear division GO:0051784 3 0.015
gtp catabolic process GO:0006184 2 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
interspecies interaction between organisms GO:0044419 4 0.015
response to topologically incorrect protein GO:0035966 2 0.015
determination of bilateral symmetry GO:0009855 204 0.015
positive regulation of synapse assembly GO:0051965 1 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.014
tissue remodeling GO:0048771 4 0.014
positive regulation of secretion GO:0051047 1 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
cortical actin cytoskeleton organization GO:0030866 1 0.014
lysosomal transport GO:0007041 2 0.014
synaptic vesicle localization GO:0097479 1 0.014
cellular component biogenesis GO:0044085 178 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
cellular protein catabolic process GO:0044257 4 0.014
cytosolic calcium ion transport GO:0060401 3 0.014
oxoacid metabolic process GO:0043436 31 0.014
regulation of transporter activity GO:0032409 2 0.014
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
generation of neurons GO:0048699 385 0.014
cellular amine metabolic process GO:0044106 2 0.014
neuron differentiation GO:0030182 353 0.014
regulation of cell shape GO:0008360 1 0.014
negative regulation of defense response GO:0031348 2 0.014
spindle assembly involved in mitosis GO:0090307 1 0.014
developmental growth GO:0048589 166 0.014
cellular ketone metabolic process GO:0042180 11 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
atp catabolic process GO:0006200 4 0.014
striated muscle cell development GO:0055002 108 0.014
neuromuscular synaptic transmission GO:0007274 2 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
immune response GO:0006955 28 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
regulation of cellular ph GO:0030641 1 0.013
positive regulation of gene expression GO:0010628 71 0.013
synaptic vesicle endocytosis GO:0048488 1 0.013
response to corticosteroid GO:0031960 1 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
membrane invagination GO:0010324 1 0.013
regulation of reproductive process GO:2000241 4 0.013
response to external stimulus GO:0009605 264 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
axonogenesis GO:0007409 152 0.013
regulation of sequestering of calcium ion GO:0051282 4 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
cell matrix adhesion GO:0007160 4 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
primary neural tube formation GO:0014020 1 0.013
cell part morphogenesis GO:0032990 246 0.013
chordate embryonic development GO:0043009 271 0.013
neuroblast proliferation GO:0007405 2 0.013
negative regulation of protein import into nucleus GO:0042308 2 0.013
negative regulation of cell communication GO:0010648 96 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
superoxide metabolic process GO:0006801 2 0.013
amine metabolic process GO:0009308 2 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
system process GO:0003008 185 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.012
protein polymerization GO:0051258 4 0.012
oocyte maturation GO:0001556 4 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
response to stress GO:0006950 263 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
phagocytosis GO:0006909 3 0.012
muscle cell development GO:0055001 115 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
regulation of sodium ion transport GO:0002028 2 0.012
regulation of gene expression GO:0010468 265 0.012
positive regulation of multi organism process GO:0043902 3 0.012
regulation of metabolic process GO:0019222 359 0.012
Mouse
central nervous system development GO:0007417 387 0.012
interaction with host GO:0051701 4 0.012
regulation of cell activation GO:0050865 1 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.011
muscle cell differentiation GO:0042692 139 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
cilium assembly GO:0042384 58 0.011
regulation of cellular response to oxidative stress GO:1900407 2 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
positive regulation of oocyte development GO:0060282 1 0.011
rna localization GO:0006403 4 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
cilium organization GO:0044782 71 0.011
negative regulation of secretion GO:0051048 2 0.011
skeletal system morphogenesis GO:0048705 102 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
endocrine process GO:0050886 2 0.011
regulation of tube size GO:0035150 2 0.011
response to hydrogen peroxide GO:0042542 3 0.011
nuclear export GO:0051168 1 0.011
protein localization to plasma membrane GO:0072659 1 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
signal transduction GO:0007165 455 0.011
Mouse
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
response to wounding GO:0009611 116 0.011
negative regulation of cytokine production GO:0001818 1 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
axon development GO:0061564 166 0.011
phagocytosis engulfment GO:0006911 1 0.011
b cell activation GO:0042113 2 0.011
macromolecule modification GO:0043412 111 0.011
cytoplasm organization GO:0007028 4 0.011
regulation of jun kinase activity GO:0043506 3 0.011
lipid catabolic process GO:0016042 4 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
renal tubule morphogenesis GO:0061333 1 0.011
response to unfolded protein GO:0006986 2 0.010
single organism membrane fusion GO:0044801 2 0.010
nephron epithelium morphogenesis GO:0072088 1 0.010
regulation of ph GO:0006885 3 0.010
mitotic cytokinesis GO:0000281 3 0.010
reflex GO:0060004 2 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
regulation of endothelial cell differentiation GO:0045601 3 0.010
skeletal system development GO:0001501 181 0.010
actin filament polymerization GO:0030041 2 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
embryonic skeletal system development GO:0048706 97 0.010
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.010
protein polyubiquitination GO:0000209 4 0.010
regulation of developmental process GO:0050793 247 0.010
embryonic cranial skeleton morphogenesis GO:0048701 90 0.010
cellular component disassembly GO:0022411 1 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.010
receptor recycling GO:0001881 4 0.010
regulation of cell communication GO:0010646 232 0.010
Mouse
meiotic nuclear division GO:0007126 4 0.010
stem cell division GO:0017145 1 0.010
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
retina development in camera type eye GO:0060041 146 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
positive regulation of neuron death GO:1901216 1 0.010

nenf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.018
immune system disease DOID:2914 0 0.016
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
inherited metabolic disorder DOID:655 0 0.012