Danio rerio

0 known processes

eng1a

engrailed 1a

(Aliases: zgc:100771,en1,eng1,en-1,ENG-1)

eng1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
chemotaxis GO:0006935 104 0.888
Fly
apoptotic process involved in development GO:1902742 2 0.857
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.811
Fly
regionalization GO:0003002 274 0.752
Zebrafish Mouse Fly
larval development GO:0002164 2 0.731
midbrain development GO:0030901 28 0.697
Zebrafish Mouse
heart development GO:0007507 313 0.696
tube morphogenesis GO:0035239 349 0.583
apoptotic process involved in morphogenesis GO:0060561 2 0.553
Zebrafish
central nervous system projection neuron axonogenesis GO:0021952 15 0.499
Fly
cell migration GO:0016477 237 0.486
single organism organelle organization GO:1902589 199 0.476
appendage development GO:0048736 80 0.464
Mouse Fly
neural tube patterning GO:0021532 33 0.459
Zebrafish Mouse
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.448
Zebrafish
locomotion GO:0040011 313 0.440
Worm Fly
mesoderm morphogenesis GO:0048332 51 0.435
nitrogen compound metabolic process GO:0006807 319 0.431
Mouse Worm Fly
cellular response to growth factor stimulus GO:0071363 39 0.422
epithelial tube morphogenesis GO:0060562 148 0.396
single organism membrane fusion GO:0044801 2 0.381
Worm
response to growth factor GO:0070848 39 0.374
heart morphogenesis GO:0003007 156 0.361
axon development GO:0061564 166 0.346
Fly
heterocycle metabolic process GO:0046483 290 0.345
Mouse Worm Fly
central nervous system development GO:0007417 387 0.345
Zebrafish Mouse Fly
embryonic pectoral fin morphogenesis GO:0035118 24 0.343
axon guidance GO:0007411 86 0.329
Fly
connective tissue development GO:0061448 99 0.316
immune system process GO:0002376 241 0.312
cellular component morphogenesis GO:0032989 336 0.308
Fly
midbrain hindbrain boundary development GO:0030917 23 0.303
Zebrafish Mouse
cell motility GO:0048870 244 0.299
olfactory lobe development GO:0021988 4 0.297
forebrain development GO:0030900 96 0.290
Fly
negative regulation of cellular process GO:0048523 283 0.288
Worm Fly
embryonic limb morphogenesis GO:0030326 2 0.280
Mouse
nucleic acid metabolic process GO:0090304 244 0.264
Mouse Worm Fly
patterning of blood vessels GO:0001569 15 0.260
regulation of anatomical structure morphogenesis GO:0022603 130 0.260
nephron tubule morphogenesis GO:0072078 1 0.259
cellular component movement GO:0006928 335 0.253
Fly
sensory system development GO:0048880 76 0.247
regulation of cellular response to growth factor stimulus GO:0090287 35 0.243
forebrain cell migration GO:0021885 1 0.237
outflow tract morphogenesis GO:0003151 1 0.233
cell morphogenesis involved in differentiation GO:0000904 195 0.227
Fly
cellular macromolecule metabolic process GO:0044260 391 0.226
Mouse Worm Fly
response to chemical GO:0042221 320 0.211
Fly
head development GO:0060322 303 0.210
Zebrafish Mouse Fly
cellular biosynthetic process GO:0044249 286 0.210
Mouse Worm Fly
regulation of axonogenesis GO:0050770 32 0.210
mesoderm development GO:0007498 88 0.208
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.201
rostrocaudal neural tube patterning GO:0021903 29 0.199
Zebrafish Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.198
Mouse Worm Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.198
localization of cell GO:0051674 244 0.191
morphogenesis of an epithelium GO:0002009 333 0.190
stem cell differentiation GO:0048863 117 0.190
Fly
digestive system development GO:0055123 289 0.188
cellular nitrogen compound metabolic process GO:0034641 290 0.188
Mouse Worm Fly
hindbrain formation GO:0021576 3 0.187
cerebellum formation GO:0021588 2 0.186
regulation of nitrogen compound metabolic process GO:0051171 251 0.183
Mouse Worm Fly
rna biosynthetic process GO:0032774 181 0.180
Mouse Worm Fly
neuron projection morphogenesis GO:0048812 161 0.179
Fly
neuron development GO:0048666 262 0.177
Mouse Fly
cell proliferation GO:0008283 80 0.176
skeletal muscle thin filament assembly GO:0030240 4 0.176
regulation of macromolecule metabolic process GO:0060255 317 0.174
Mouse Worm Fly
glial cell migration GO:0008347 3 0.174
cell projection morphogenesis GO:0048858 244 0.173
Fly
cell migration involved in gastrulation GO:0042074 79 0.167
cellular response to organic substance GO:0071310 105 0.165
generation of neurons GO:0048699 385 0.164
Zebrafish Mouse Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.162
Worm Fly
digestive tract development GO:0048565 265 0.158
mesoderm formation GO:0001707 43 0.154
mesenchyme development GO:0060485 127 0.150
regulation of axon guidance GO:1902667 8 0.149
regulation of epithelial cell proliferation GO:0050678 3 0.149
central nervous system neuron axonogenesis GO:0021955 18 0.148
Fly
neuron differentiation GO:0030182 353 0.145
Zebrafish Mouse Fly
skeletal system morphogenesis GO:0048705 102 0.144
striated muscle cell differentiation GO:0051146 129 0.143
regulation of cellular component size GO:0032535 30 0.140
endocardial cushion formation GO:0003272 2 0.139
regulation of cell fate commitment GO:0010453 22 0.133
organic cyclic compound metabolic process GO:1901360 301 0.133
Mouse Worm Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.132
Mouse Worm Fly
artery development GO:0060840 22 0.131
developmental programmed cell death GO:0010623 4 0.130
Zebrafish
cell fate commitment GO:0045165 99 0.127
Zebrafish Worm Fly
taxis GO:0042330 109 0.126
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.126
Zebrafish Mouse Worm
motor neuron axon guidance GO:0008045 23 0.125
ameboidal type cell migration GO:0001667 143 0.122
branching morphogenesis of an epithelial tube GO:0048754 15 0.119
regulation of binding GO:0051098 3 0.117
cell part morphogenesis GO:0032990 246 0.115
Fly
pigmentation GO:0043473 85 0.112
Mouse
regulation of neuron differentiation GO:0045664 56 0.111
regulation of heart growth GO:0060420 2 0.107
axonogenesis GO:0007409 152 0.106
Fly
regulation of cellular component organization GO:0051128 86 0.103
morphogenesis of a branching epithelium GO:0061138 16 0.102
axon extension GO:0048675 45 0.101
nucleobase containing compound metabolic process GO:0006139 274 0.101
Mouse Worm Fly
specification of symmetry GO:0009799 204 0.100
cell fate specification GO:0001708 68 0.099
Zebrafish Worm
programmed cell death GO:0012501 119 0.098
Zebrafish
morphogenesis of a branching structure GO:0001763 21 0.097
cell projection organization GO:0030030 284 0.096
Fly
nitric oxide mediated signal transduction GO:0007263 2 0.096
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.092
cartilage development GO:0051216 96 0.092
regulation of response to stimulus GO:0048583 269 0.092
muscle organ development GO:0007517 101 0.089
regulation of gene expression GO:0010468 265 0.088
Mouse Worm Fly
regulation of cell shape GO:0008360 1 0.088
epithelial tube formation GO:0072175 19 0.087
posterior lateral line system development GO:0048915 46 0.087
muscle cell development GO:0055001 115 0.086
blood vessel morphogenesis GO:0048514 216 0.086
nephron morphogenesis GO:0072028 2 0.086
anterior posterior pattern specification GO:0009952 152 0.085
Zebrafish Mouse Fly
gene expression GO:0010467 252 0.085
Mouse Worm Fly
hair cell differentiation GO:0035315 32 0.085
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.085
Mouse Worm Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.085
olfactory bulb development GO:0021772 4 0.085
axis elongation GO:0003401 31 0.085
gastrulation GO:0007369 208 0.084
muscle structure development GO:0061061 196 0.084
angiogenesis GO:0001525 158 0.083
ectodermal placode development GO:0071696 37 0.083
cellular macromolecule biosynthetic process GO:0034645 224 0.082
Mouse Worm Fly
blood vessel development GO:0001568 246 0.082
formation of primary germ layer GO:0001704 62 0.081
lateral line development GO:0048882 66 0.081
regulation of cellular biosynthetic process GO:0031326 245 0.081
Mouse Worm Fly
response to stress GO:0006950 263 0.080
Fly
rna metabolic process GO:0016070 219 0.080
Mouse Worm Fly
negative regulation of biological process GO:0048519 304 0.079
Worm Fly
behavior GO:0007610 74 0.079
cardiac chamber development GO:0003205 19 0.079
neuron fate determination GO:0048664 2 0.079
negative regulation of metabolic process GO:0009892 86 0.075
Worm Fly
skeletal myofibril assembly GO:0014866 7 0.075
vasculature development GO:0001944 278 0.075
somitogenesis GO:0001756 87 0.074
skeletal system development GO:0001501 181 0.074
skin development GO:0043588 54 0.072
Worm
multicellular organism growth GO:0035264 4 0.072
Mouse
epithelial cell differentiation GO:0030855 116 0.071
Worm
reactive oxygen species metabolic process GO:0072593 6 0.071
digestive tract morphogenesis GO:0048546 231 0.071
regulation of chemotaxis GO:0050920 18 0.070
regulation of nucleic acid templated transcription GO:1903506 213 0.070
Mouse Worm Fly
mesodermal cell migration GO:0008078 12 0.069
aromatic compound biosynthetic process GO:0019438 217 0.069
Mouse Worm Fly
regulation of cellular metabolic process GO:0031323 320 0.069
Mouse Worm Fly
cellular response to endogenous stimulus GO:0071495 68 0.069
embryonic heart tube development GO:0035050 133 0.069
telencephalon development GO:0021537 14 0.068
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.067
Mouse Worm Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.066
Mouse Worm Fly
neuroblast differentiation GO:0014016 1 0.066
Fly
skeletal muscle organ development GO:0060538 78 0.066
nucleobase containing compound biosynthetic process GO:0034654 205 0.065
Mouse Worm Fly
regulation of protein complex assembly GO:0043254 3 0.064
cellular protein complex assembly GO:0043623 19 0.064
positive regulation of endothelial cell migration GO:0010595 2 0.064
negative regulation of rna metabolic process GO:0051253 48 0.064
Worm Fly
cardiac muscle cell differentiation GO:0055007 30 0.064
venous blood vessel morphogenesis GO:0048845 3 0.063
cell morphogenesis GO:0000902 289 0.063
Fly
nephron epithelium morphogenesis GO:0072088 1 0.063
negative regulation of chemotaxis GO:0050922 4 0.063
ectodermal placode morphogenesis GO:0071697 32 0.062
regulation of primary metabolic process GO:0080090 311 0.062
Mouse Worm Fly
regulation of protein binding GO:0043393 3 0.061
regulation of metabolic process GO:0019222 359 0.061
Mouse Worm Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.060
Worm Fly
neuron projection guidance GO:0097485 86 0.060
Fly
positive regulation of epithelial cell migration GO:0010634 2 0.060
brain development GO:0007420 293 0.059
Zebrafish Mouse Fly
epidermis development GO:0008544 48 0.059
Worm
renal system development GO:0072001 94 0.059
response to fibroblast growth factor GO:0071774 22 0.058
regulation of developmental process GO:0050793 247 0.056
hemopoiesis GO:0030097 183 0.056
neuron projection development GO:0031175 180 0.055
Fly
determination of left right symmetry GO:0007368 179 0.055
post embryonic organ development GO:0048569 4 0.055
Fly
nucleoside monophosphate catabolic process GO:0009125 4 0.055
otic placode formation GO:0043049 23 0.054
regulation of cell communication GO:0010646 232 0.054
odontogenesis of dentin containing tooth GO:0042475 1 0.053
positive regulation of striated muscle tissue development GO:0045844 1 0.053
negative regulation of transcription dna templated GO:0045892 45 0.053
Worm Fly
membrane fusion GO:0061025 2 0.053
Worm
embryonic appendage morphogenesis GO:0035113 30 0.052
Mouse
dorsal ventral pattern formation GO:0009953 125 0.052
Mouse
otic vesicle development GO:0071599 42 0.052
regulation of cell fate specification GO:0042659 20 0.052
embryonic organ development GO:0048568 381 0.051
developmental growth GO:0048589 166 0.050
specification of organ identity GO:0010092 2 0.050
bmp signaling pathway GO:0030509 52 0.050
pronephric glomerulus development GO:0039021 13 0.050
peripheral nervous system development GO:0007422 55 0.050
pectoral fin development GO:0033339 50 0.050
negative regulation of striated muscle tissue development GO:0045843 2 0.049
convergent extension involved in gastrulation GO:0060027 71 0.049
response to organic substance GO:0010033 153 0.049
tissue migration GO:0090130 37 0.049
primary neural tube formation GO:0014020 1 0.049
axon extension involved in axon guidance GO:0048846 10 0.048
venous blood vessel development GO:0060841 9 0.048
regulation of rna biosynthetic process GO:2001141 213 0.048
Mouse Worm Fly
formation of anatomical boundary GO:0048859 14 0.048
Worm
regulation of cell differentiation GO:0045595 142 0.047
neuron projection extension GO:1990138 45 0.047
vestibular receptor cell development GO:0060118 3 0.046
pectoral fin morphogenesis GO:0035138 29 0.046
skeletal muscle tissue development GO:0007519 67 0.046
regulation of axon extension GO:0030516 24 0.046
regulation of cell development GO:0060284 100 0.045
positive regulation of muscle tissue development GO:1901863 1 0.045
regulation of photoreceptor cell differentiation GO:0046532 2 0.044
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.044
somite specification GO:0001757 12 0.044
neural tube formation GO:0001841 16 0.043
maintenance of location GO:0051235 4 0.043
regulation of organ growth GO:0046620 3 0.043
regulation of extent of cell growth GO:0061387 29 0.042
rhombomere 6 development GO:0021572 4 0.042
muscle cell differentiation GO:0042692 139 0.042
striated muscle cell development GO:0055002 108 0.042
regulation of anatomical structure size GO:0090066 33 0.042
somatic muscle development GO:0007525 4 0.041
regulation of biological quality GO:0065008 263 0.041
positive regulation of cell adhesion GO:0045785 1 0.041
heart looping GO:0001947 94 0.041
death GO:0016265 121 0.041
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.041
Mouse Worm Fly
embryonic organ morphogenesis GO:0048562 274 0.040
regulation of rna metabolic process GO:0051252 224 0.040
Mouse Worm Fly
embryonic viscerocranium morphogenesis GO:0048703 52 0.040
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.039
anterior commissure morphogenesis GO:0021960 3 0.039
Fly
epithelium migration GO:0090132 25 0.038
cardiocyte differentiation GO:0035051 44 0.038
regulation of signal transduction GO:0009966 225 0.038
stem cell development GO:0048864 82 0.038
response to wounding GO:0009611 116 0.038
regulation of cardiac muscle tissue development GO:0055024 1 0.038
epidermal cell differentiation GO:0009913 36 0.038
Worm
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.038
aging GO:0007568 2 0.037
appendage morphogenesis GO:0035107 56 0.037
Mouse Fly
transcription dna templated GO:0006351 181 0.037
Mouse Worm Fly
lipid storage GO:0019915 1 0.037
embryonic cranial skeleton morphogenesis GO:0048701 90 0.037
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.037
organ formation GO:0048645 17 0.037
regulation of multicellular organismal process GO:0051239 277 0.036
posterior lateral line development GO:0048916 38 0.036
epidermal cell fate specification GO:0009957 4 0.036
Worm
ectodermal placode formation GO:0060788 26 0.036
kidney development GO:0001822 92 0.036
kidney epithelium development GO:0072073 23 0.036
cellular component assembly involved in morphogenesis GO:0010927 107 0.036
otic vesicle formation GO:0030916 27 0.035
negative regulation of response to stimulus GO:0048585 104 0.035
exocrine system development GO:0035272 28 0.035
regulation of organelle organization GO:0033043 29 0.035
regulation of biosynthetic process GO:0009889 250 0.034
Mouse Worm Fly
cellular aromatic compound metabolic process GO:0006725 295 0.034
Mouse Worm Fly
embryonic epithelial tube formation GO:0001838 17 0.034
gland development GO:0048732 143 0.034
multicellular organism reproduction GO:0032504 35 0.033
positive regulation of muscle organ development GO:0048636 1 0.033
lipid homeostasis GO:0055088 3 0.033
protein complex assembly GO:0006461 30 0.033
homeostatic process GO:0042592 142 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
Mouse Worm Fly
biosynthetic process GO:0009058 294 0.033
Mouse Worm Fly
nephron tubule epithelial cell differentiation GO:0072160 1 0.033
cellular response to chemical stimulus GO:0070887 157 0.032
regulation of multicellular organismal development GO:2000026 223 0.032
actin filament polymerization GO:0030041 2 0.032
central nervous system neuron differentiation GO:0021953 74 0.032
Fly
posterior lateral line neuromast primordium migration GO:0048920 12 0.032
primitive hemopoiesis GO:0060215 27 0.031
lateral line system development GO:0048925 76 0.031
axonal fasciculation GO:0007413 11 0.031
lymphoid lineage cell migration into thymus GO:0097535 4 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.031
Worm Fly
response to external stimulus GO:0009605 264 0.031
Fly
cardiac muscle fiber development GO:0048739 3 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.030
neuromast primordium migration GO:0048883 12 0.030
renal tubule morphogenesis GO:0061333 1 0.030
negative regulation of map kinase activity GO:0043407 2 0.029
apoptotic process GO:0006915 116 0.029
Zebrafish
mitochondrion organization GO:0007005 4 0.029
regulation of locomotion GO:0040012 55 0.028
locus ceruleus development GO:0021703 3 0.028
cardiac muscle tissue development GO:0048738 48 0.028
aorta development GO:0035904 4 0.028
multi organism reproductive process GO:0044703 36 0.028
positive regulation of gene expression GO:0010628 71 0.028
Mouse Worm Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.028
regulation of signaling GO:0023051 235 0.028
neural plate development GO:0001840 10 0.027
taste bud formation GO:0061195 3 0.027
neuron fate specification GO:0048665 20 0.027
gamete generation GO:0007276 33 0.027
spinal cord association neuron differentiation GO:0021527 1 0.027
embryonic camera type eye formation GO:0060900 10 0.027
mesenchyme morphogenesis GO:0072132 5 0.027
negative regulation of signal transduction GO:0009968 94 0.027
hematopoietic or lymphoid organ development GO:0048534 191 0.027
regulation of angiogenesis GO:0045765 26 0.027
muscle tissue development GO:0060537 110 0.027
multicellular organismal reproductive process GO:0048609 35 0.027
regulation of axon extension involved in axon guidance GO:0048841 6 0.027
ribonucleoside monophosphate catabolic process GO:0009158 4 0.027
pharyngeal muscle development GO:0043282 4 0.026
determination of bilateral symmetry GO:0009855 204 0.026
periodic partitioning GO:0007365 1 0.026
cellular component assembly GO:0022607 170 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
immune system development GO:0002520 191 0.026
neuroblast fate determination GO:0007400 1 0.026
Fly
negative regulation of signaling GO:0023057 96 0.026
growth GO:0040007 174 0.026
Mouse
mechanosensory lateral line system development GO:0048881 49 0.026
vestibular receptor cell differentiation GO:0060114 3 0.026
positive regulation of cellular process GO:0048522 201 0.025
Mouse Worm Fly
positive regulation of locomotion GO:0040017 14 0.025
tissue remodeling GO:0048771 4 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
Mouse Worm Fly
myofibril assembly GO:0030239 48 0.025
embryonic heart tube morphogenesis GO:0003143 108 0.025
regulation of behavior GO:0050795 24 0.025
purine nucleoside monophosphate catabolic process GO:0009128 4 0.025
regulation of endothelial cell proliferation GO:0001936 1 0.025
retina development in camera type eye GO:0060041 146 0.025
negative regulation of developmental process GO:0051093 65 0.025
hindbrain morphogenesis GO:0021575 22 0.025
endothelial cell fate commitment GO:0060839 3 0.025
organic substance biosynthetic process GO:1901576 289 0.025
Mouse Worm Fly
cardiac cell fate commitment GO:0060911 1 0.024
fin morphogenesis GO:0033334 53 0.024
positive regulation of developmental process GO:0051094 50 0.024
developmental growth involved in morphogenesis GO:0060560 86 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
positive regulation of biosynthetic process GO:0009891 68 0.024
Mouse Worm Fly
neuron fate commitment GO:0048663 26 0.024
Zebrafish
negative regulation of muscle tissue development GO:1901862 2 0.024
striated muscle tissue development GO:0014706 110 0.024
endocardial cushion morphogenesis GO:0003203 3 0.024
negative regulation of rna biosynthetic process GO:1902679 45 0.024
Worm Fly
axonal defasciculation GO:0007414 2 0.023
organelle organization GO:0006996 227 0.023
cerebellar granule cell differentiation GO:0021707 3 0.023
response to hexose GO:0009746 3 0.023
chemical homeostasis GO:0048878 49 0.023
morphogenesis of embryonic epithelium GO:0016331 30 0.023
limbic system development GO:0021761 16 0.023
cerebellar granular layer morphogenesis GO:0021683 3 0.023
inner ear development GO:0048839 126 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
positive regulation of cellular biosynthetic process GO:0031328 68 0.023
Mouse Worm Fly
olfactory bulb axon guidance GO:0071678 3 0.022
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.022
eye morphogenesis GO:0048592 144 0.022
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.022
diencephalon development GO:0021536 58 0.022
cellular response to estrogen stimulus GO:0071391 24 0.022
rhombomere 5 development GO:0021571 4 0.022
negative regulation of apoptotic process GO:0043066 55 0.022
epithelial cell differentiation involved in kidney development GO:0035850 13 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.021
Mouse Worm Fly
positive regulation of skeletal muscle tissue development GO:0048643 1 0.021
mesodermal cell differentiation GO:0048333 21 0.021
regulation of apoptotic process GO:0042981 98 0.021
sensory organ development GO:0007423 393 0.021
lymphoid lineage cell migration GO:0097534 4 0.021
inner ear receptor cell differentiation GO:0060113 29 0.021
nephron development GO:0072006 31 0.021
dendrite guidance GO:0070983 0 0.021
regulation of system process GO:0044057 40 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
negative regulation of axon guidance GO:1902668 1 0.021
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.021
protein complex biogenesis GO:0070271 30 0.021
forebrain regionalization GO:0021871 4 0.021
carbohydrate derivative metabolic process GO:1901135 61 0.020
endocrine system development GO:0035270 65 0.020
cell division GO:0051301 20 0.020
positive regulation of wound healing GO:0090303 1 0.020
positive regulation of striated muscle cell differentiation GO:0051155 1 0.020
cerebellar granular layer formation GO:0021684 3 0.020
regulation of organelle assembly GO:1902115 4 0.020
positive regulation of rna metabolic process GO:0051254 59 0.020
Mouse Worm Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.020
central nervous system neuron development GO:0021954 29 0.020
Fly
nephron epithelium development GO:0072009 16 0.020
ear morphogenesis GO:0042471 64 0.020
cell differentiation involved in kidney development GO:0061005 13 0.020
regulation of reactive oxygen species metabolic process GO:2000377 2 0.020
endosomal transport GO:0016197 2 0.020
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.020
nephric duct development GO:0072176 13 0.020
dna templated transcription elongation GO:0006354 3 0.020
response to fungus GO:0009620 25 0.020
Fly
positive regulation of dna metabolic process GO:0051054 1 0.020
protein catabolic process GO:0030163 7 0.019
retina morphogenesis in camera type eye GO:0060042 79 0.019
cellular response to external stimulus GO:0071496 2 0.019
positive regulation of metabolic process GO:0009893 108 0.019
Mouse Worm Fly
somite development GO:0061053 96 0.019
negative regulation of programmed cell death GO:0043069 58 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
regulation of myotube differentiation GO:0010830 2 0.019
cerebellum morphogenesis GO:0021587 10 0.019
cardiac chamber morphogenesis GO:0003206 12 0.019
regulation of tissue remodeling GO:0034103 2 0.019
myeloid cell homeostasis GO:0002262 56 0.019
positive regulation of stem cell proliferation GO:2000648 1 0.019
regulation of cellular response to stress GO:0080135 20 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.019
positive regulation of transport GO:0051050 2 0.018
myeloid cell differentiation GO:0030099 86 0.018
negative regulation of gene expression GO:0010629 65 0.018
Worm Fly
embryonic eye morphogenesis GO:0048048 30 0.018
inner ear morphogenesis GO:0042472 63 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.018
Worm Fly
regulation of stem cell proliferation GO:0072091 2 0.018
leukocyte chemotaxis GO:0030595 12 0.018
regulation of cell motility GO:2000145 46 0.018
determination of heart left right asymmetry GO:0061371 117 0.018
protein polymerization GO:0051258 4 0.018
epithelial cell morphogenesis GO:0003382 2 0.018
inner ear receptor cell development GO:0060119 20 0.018
regulation of cell projection assembly GO:0060491 4 0.018
regulation of cell size GO:0008361 29 0.018
hindbrain development GO:0030902 91 0.018
Mouse
negative regulation of cell fate commitment GO:0010454 13 0.018
protein metabolic process GO:0019538 183 0.018
embryonic skeletal system development GO:0048706 97 0.018
regulation of molecular function GO:0065009 70 0.018
photoreceptor cell fate specification GO:0043704 1 0.018
actin polymerization or depolymerization GO:0008154 2 0.018
mediolateral intercalation GO:0060031 3 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
positive regulation of cellular metabolic process GO:0031325 94 0.017
Mouse Worm Fly
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.017
blood circulation GO:0008015 87 0.017
organophosphate metabolic process GO:0019637 37 0.017
cell cycle GO:0007049 93 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
lateral inhibition GO:0046331 1 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
gliogenesis GO:0042063 45 0.017
hepatocyte proliferation GO:0072574 2 0.017
negative regulation of epithelial cell proliferation GO:0050680 1 0.017
defense response GO:0006952 47 0.017
Fly
otic vesicle morphogenesis GO:0071600 34 0.017
mesenchymal cell proliferation GO:0010463 1 0.017
convergent extension GO:0060026 118 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
Mouse Worm Fly
thyroid gland development GO:0030878 12 0.016
cellular macromolecular complex assembly GO:0034622 24 0.016
negative regulation of cell communication GO:0010648 96 0.016
positive regulation of stress activated mapk cascade GO:0032874 3 0.016
membrane organization GO:0061024 21 0.016
Worm
negative regulation of multicellular organismal process GO:0051241 69 0.016
endocardial cushion development GO:0003197 6 0.016
neuroepithelial cell differentiation GO:0060563 26 0.016
kupffer s vesicle development GO:0070121 50 0.016
regulation of bone remodeling GO:0046850 2 0.016
reactive oxygen species biosynthetic process GO:1903409 1 0.016
regulation of cell death GO:0010941 103 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
Mouse Worm Fly

eng1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.099
urinary system disease DOID:18 0 0.091
musculoskeletal system disease DOID:17 0 0.039
bone disease DOID:0080001 0 0.033
connective tissue disease DOID:65 0 0.033
kidney disease DOID:557 0 0.033
bone development disease DOID:0080006 0 0.028
sensory system disease DOID:0050155 0 0.028
nervous system disease DOID:863 0 0.028