Danio rerio

31 known processes

wls

wntless homolog (Drosophila)

(Aliases: wu:fb36d04,sb:cb610,wu:fb44d10,zgc:64091,gpr117,wu:fb50c06,gpr177)

wls biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract morphogenesis GO:0048546 231 0.978
Mouse Worm
somatic stem cell maintenance GO:0035019 1 0.926
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.854
morphogenesis of an epithelium GO:0002009 333 0.794
cell morphogenesis GO:0000902 289 0.766
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.745
convergent extension involved in gastrulation GO:0060027 71 0.740
tissue homeostasis GO:0001894 25 0.720
cell surface receptor signaling pathway GO:0007166 325 0.715
Mouse Worm Fly
endocardial cushion formation GO:0003272 2 0.710
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.708
response to stress GO:0006950 263 0.666
regulation of signaling GO:0023051 235 0.645
Fly
neuron development GO:0048666 262 0.641
embryonic organ development GO:0048568 381 0.632
gastrulation GO:0007369 208 0.631
Mouse Worm
sensory organ development GO:0007423 393 0.628
single organism transport GO:0044765 206 0.617
Fly
tube morphogenesis GO:0035239 349 0.607
Mouse Worm
regulation of multicellular organismal development GO:2000026 223 0.604
inner ear morphogenesis GO:0042472 63 0.591
sensory organ morphogenesis GO:0090596 200 0.544
Fly
wnt signaling pathway GO:0016055 80 0.535
Mouse Worm Fly
response to external stimulus GO:0009605 264 0.534
cell fate specification GO:0001708 68 0.532
Worm
epithelial tube morphogenesis GO:0060562 148 0.524
kidney development GO:0001822 92 0.524
mesenchyme development GO:0060485 127 0.507
brain development GO:0007420 293 0.488
digestive tract development GO:0048565 265 0.482
Mouse Worm
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.478
regulation of biological quality GO:0065008 263 0.476
negative regulation of cell communication GO:0010648 96 0.475
endocardial cushion morphogenesis GO:0003203 3 0.461
neuron differentiation GO:0030182 353 0.458
neuron projection development GO:0031175 180 0.453
negative regulation of biological process GO:0048519 304 0.436
neuroblast proliferation GO:0007405 2 0.425
single organism localization GO:1902578 225 0.414
Worm Fly
cell projection organization GO:0030030 284 0.405
negative regulation of multicellular organismal process GO:0051241 69 0.391
cellular component morphogenesis GO:0032989 336 0.386
specification of organ identity GO:0010092 2 0.381
mesoderm development GO:0007498 88 0.377
Mouse
generation of neurons GO:0048699 385 0.365
canonical wnt signaling pathway GO:0060070 48 0.363
stem cell maintenance GO:0019827 4 0.355
protein import into nucleus GO:0006606 3 0.354
auditory receptor cell differentiation GO:0042491 15 0.349
regulation of protein import into nucleus GO:0042306 2 0.346
establishment of localization in cell GO:0051649 77 0.342
Worm Fly
larval development GO:0002164 2 0.339
Worm
regulation of cardiac muscle tissue development GO:0055024 1 0.332
regulation of wnt signaling pathway GO:0030111 53 0.331
Fly
cell fate commitment GO:0045165 99 0.331
Worm
cell morphogenesis involved in differentiation GO:0000904 195 0.329
cellular localization GO:0051641 97 0.327
Worm Fly
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.325
ossification GO:0001503 23 0.320
inner ear development GO:0048839 126 0.319
locomotion GO:0040011 313 0.318
Worm
urogenital system development GO:0001655 97 0.317
regulation of cytoplasmic transport GO:1903649 4 0.305
determination of left right symmetry GO:0007368 179 0.303
localization of cell GO:0051674 244 0.303
Worm
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.300
regulation of epithelial cell proliferation GO:0050678 3 0.295
chondrocyte development GO:0002063 4 0.287
organ formation GO:0048645 17 0.284
regulation of anatomical structure morphogenesis GO:0022603 130 0.283
heart development GO:0007507 313 0.281
regulation of protein targeting GO:1903533 2 0.279
immune system development GO:0002520 191 0.277
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.275
negative regulation of response to stimulus GO:0048585 104 0.275
stem cell division GO:0017145 1 0.272
homeostatic process GO:0042592 142 0.269
regulation of signal transduction GO:0009966 225 0.268
Fly
response to hormone GO:0009725 48 0.264
ear development GO:0043583 127 0.261
regulation of axonogenesis GO:0050770 32 0.261
optic placode formation involved in camera type eye formation GO:0046619 3 0.260
multi organism reproductive process GO:0044703 36 0.254
negative regulation of wnt signaling pathway GO:0030178 30 0.246
regulation of multicellular organismal process GO:0051239 277 0.246
cell death GO:0008219 121 0.243
erk1 and erk2 cascade GO:0070371 4 0.243
sprouting angiogenesis GO:0002040 53 0.241
inner ear receptor cell differentiation GO:0060113 29 0.241
immune system process GO:0002376 241 0.241
multi organism process GO:0051704 134 0.239
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.238
notch signaling pathway GO:0007219 35 0.237
cellular component biogenesis GO:0044085 178 0.236
direct ossification GO:0036072 3 0.235
specification of axis polarity GO:0065001 4 0.235
cellular response to external stimulus GO:0071496 2 0.231
regulation of proteolysis GO:0030162 24 0.229
neuron projection morphogenesis GO:0048812 161 0.228
regulation of oligodendrocyte differentiation GO:0048713 1 0.228
cell motility GO:0048870 244 0.220
Worm
regulation of metabolic process GO:0019222 359 0.218
regulation of embryonic development GO:0045995 47 0.211
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.209
cellular component movement GO:0006928 335 0.205
Worm
hematopoietic or lymphoid organ development GO:0048534 191 0.205
positive regulation of muscle organ development GO:0048636 1 0.204
multicellular organismal homeostasis GO:0048871 29 0.204
cell projection morphogenesis GO:0048858 244 0.202
positive regulation of transport GO:0051050 2 0.202
Fly
axonogenesis GO:0007409 152 0.202
regulation of cell development GO:0060284 100 0.200
neural tube development GO:0021915 62 0.198
stem cell proliferation GO:0072089 4 0.197
cell part morphogenesis GO:0032990 246 0.194
regulation of organ growth GO:0046620 3 0.190
chordate embryonic development GO:0043009 271 0.186
ventricular cardiac muscle tissue development GO:0003229 3 0.186
positive regulation of stem cell proliferation GO:2000648 1 0.186
nephron development GO:0072006 31 0.184
cell cell signaling GO:0007267 52 0.184
convergent extension GO:0060026 118 0.183
cardiac ventricle development GO:0003231 9 0.183
response to nutrient GO:0007584 3 0.181
regulation of protein localization to nucleus GO:1900180 2 0.181
regulation of cellular component movement GO:0051270 55 0.181
Worm
embryonic camera type eye development GO:0031076 29 0.179
germ line stem cell division GO:0042078 1 0.178
notochord development GO:0030903 54 0.175
diterpenoid biosynthetic process GO:0016102 7 0.174
regulation of developmental process GO:0050793 247 0.173
cellular macromolecule metabolic process GO:0044260 391 0.172
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.172
cellular response to dna damage stimulus GO:0006974 24 0.166
mesenchyme morphogenesis GO:0072132 5 0.165
negative regulation of cellular process GO:0048523 283 0.163
determination of bilateral symmetry GO:0009855 204 0.162
cellular response to radiation GO:0071478 4 0.162
retinoic acid metabolic process GO:0042573 9 0.159
embryonic heart tube development GO:0035050 133 0.158
negative chemotaxis GO:0050919 1 0.154
i kappab kinase nf kappab signaling GO:0007249 4 0.153
lateral inhibition GO:0046331 1 0.153
somite development GO:0061053 96 0.152
endodermal digestive tract morphogenesis GO:0061031 2 0.151
axis elongation involved in somitogenesis GO:0090245 2 0.151
multicellular organismal metabolic process GO:0044236 2 0.151
negative regulation of protein kinase b signaling GO:0051898 2 0.148
regulation of nervous system development GO:0051960 90 0.144
cell migration GO:0016477 237 0.144
Worm
regionalization GO:0003002 274 0.144
signal transduction GO:0007165 455 0.144
Mouse Worm Fly
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.143
regulation of catenin import into nucleus GO:0035412 2 0.141
single organism organelle organization GO:1902589 199 0.140
Worm
single organism biosynthetic process GO:0044711 71 0.139
mesenchymal cell development GO:0014031 78 0.138
endoderm formation GO:0001706 29 0.137
Worm
muscle structure development GO:0061061 196 0.137
regulation of heart growth GO:0060420 2 0.137
positive regulation of muscle tissue development GO:1901863 1 0.136
negative regulation of protein transport GO:0051224 3 0.136
intracellular transport GO:0046907 32 0.132
Fly
midbrain development GO:0030901 28 0.131
coagulation GO:0050817 13 0.131
morphogenesis of an epithelial fold GO:0060571 1 0.130
response to biotic stimulus GO:0009607 97 0.130
eye development GO:0001654 277 0.128
Fly
morphogenesis of a branching epithelium GO:0061138 16 0.128
regulation of cell differentiation GO:0045595 142 0.127
meiotic nuclear division GO:0007126 4 0.127
heart morphogenesis GO:0003007 156 0.125
organonitrogen compound metabolic process GO:1901564 74 0.125
regulation of chondrocyte differentiation GO:0032330 1 0.125
multicellular organismal reproductive process GO:0048609 35 0.124
immune response GO:0006955 28 0.124
mitotic cell cycle process GO:1903047 48 0.123
Worm
apical junction assembly GO:0043297 1 0.121
establishment or maintenance of cell polarity GO:0007163 29 0.120
Worm
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.119
axon development GO:0061564 166 0.118
nucleoside phosphate metabolic process GO:0006753 28 0.117
macromolecule localization GO:0033036 54 0.117
Worm Fly
regulation of erk1 and erk2 cascade GO:0070372 4 0.117
mesodermal cell migration GO:0008078 12 0.116
regulation of notch signaling pathway GO:0008593 16 0.115
respiratory system development GO:0060541 5 0.115
stem cell development GO:0048864 82 0.115
protein import GO:0017038 3 0.114
keratinocyte differentiation GO:0030216 0 0.114
mechanoreceptor differentiation GO:0042490 37 0.113
regulation of endothelial cell proliferation GO:0001936 1 0.113
regulation of stem cell differentiation GO:2000736 4 0.113
establishment of localization GO:0051234 244 0.113
Worm Fly
skeletal system development GO:0001501 181 0.113
system process GO:0003008 185 0.112
negative regulation of protein localization to nucleus GO:1900181 2 0.112
regulation of neuron differentiation GO:0045664 56 0.112
angiogenesis GO:0001525 158 0.110
establishment of protein localization to organelle GO:0072594 4 0.108
thrombocyte differentiation GO:0002574 4 0.108
death GO:0016265 121 0.108
single organism metabolic process GO:0044710 217 0.108
protein metabolic process GO:0019538 183 0.107
transport GO:0006810 220 0.107
Fly
nephron morphogenesis GO:0072028 2 0.106
establishment of cell polarity GO:0030010 18 0.106
Worm
regulation of canonical wnt signaling pathway GO:0060828 34 0.106
ectoderm development GO:0007398 9 0.105
proximal distal pattern formation GO:0009954 1 0.105
gall bladder development GO:0061010 1 0.105
organic cyclic compound biosynthetic process GO:1901362 223 0.105
mesenchymal cell proliferation GO:0010463 1 0.104
protein targeting to nucleus GO:0044744 3 0.103
cardiocyte differentiation GO:0035051 44 0.102
intramembranous ossification GO:0001957 3 0.100
epithelial cell differentiation involved in kidney development GO:0035850 13 0.100
bmp signaling pathway GO:0030509 52 0.100
developmental growth GO:0048589 166 0.098
muscle organ morphogenesis GO:0048644 8 0.097
central nervous system neuron differentiation GO:0021953 74 0.097
radial glial cell differentiation GO:0060019 2 0.097
organelle organization GO:0006996 227 0.095
Worm
fin regeneration GO:0031101 51 0.095
reciprocal meiotic recombination GO:0007131 1 0.094
negative regulation of neuron projection development GO:0010977 9 0.094
regulation of mesenchymal cell proliferation GO:0010464 1 0.094
heart formation GO:0060914 13 0.094
positive regulation of muscle cell differentiation GO:0051149 1 0.094
segment polarity determination GO:0007367 1 0.094
Fly
nuclear import GO:0051170 3 0.094
regulation of nucleocytoplasmic transport GO:0046822 2 0.092
response to external biotic stimulus GO:0043207 97 0.091
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.091
regulation of phosphorylation GO:0042325 26 0.090
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.090
cell activation GO:0001775 16 0.090
single organism reproductive process GO:0044702 40 0.090
vasculogenesis GO:0001570 41 0.089
endothelium development GO:0003158 25 0.089
meiosis i GO:0007127 1 0.089
positive regulation of histone deacetylation GO:0031065 1 0.089
phosphorus metabolic process GO:0006793 109 0.089
epithelial cell morphogenesis GO:0003382 2 0.088
cell fate commitment involved in pattern specification GO:0060581 6 0.088
positive regulation of cell cycle GO:0045787 3 0.088
neural tube patterning GO:0021532 33 0.088
gamete generation GO:0007276 33 0.087
regulation of organelle organization GO:0033043 29 0.087
Worm
positive regulation of cell proliferation GO:0008284 15 0.087
regulation of response to stimulus GO:0048583 269 0.086
Fly
protein localization GO:0008104 40 0.086
Worm Fly
hepatocyte proliferation GO:0072574 2 0.086
cognition GO:0050890 1 0.086
regulation of cellular component size GO:0032535 30 0.085
oxidation reduction process GO:0055114 41 0.084
heart looping GO:0001947 94 0.084
protein localization to nucleus GO:0034504 3 0.084
response to decreased oxygen levels GO:0036293 25 0.084
vasculature development GO:0001944 278 0.083
regulation of localization GO:0032879 104 0.082
Worm Fly
phosphorylation GO:0016310 69 0.082
phosphate containing compound metabolic process GO:0006796 108 0.082
synaptic growth at neuromuscular junction GO:0051124 2 0.081
spinal cord anterior posterior patterning GO:0021512 1 0.080
small molecule metabolic process GO:0044281 77 0.080
regulation of establishment of protein localization GO:0070201 4 0.080
Fly
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.080
heart field specification GO:0003128 1 0.080
developmental process involved in reproduction GO:0003006 27 0.080
heterocycle biosynthetic process GO:0018130 215 0.080
ear morphogenesis GO:0042471 64 0.079
regulation of cell migration GO:0030334 40 0.079
Worm
cellular component assembly GO:0022607 170 0.079
energy reserve metabolic process GO:0006112 2 0.078
oligodendrocyte differentiation GO:0048709 23 0.078
cellular aromatic compound metabolic process GO:0006725 295 0.077
regulation of anatomical structure size GO:0090066 33 0.077
positive regulation of striated muscle cell differentiation GO:0051155 1 0.077
determination of heart left right asymmetry GO:0061371 117 0.075
optic placode formation GO:0001743 4 0.074
stem cell differentiation GO:0048863 117 0.074
axis specification GO:0009798 43 0.074
Mouse
cardiac chamber development GO:0003205 19 0.074
photoreceptor cell differentiation GO:0046530 55 0.074
mesenchymal cell differentiation GO:0048762 87 0.073
biosynthetic process GO:0009058 294 0.073
behavior GO:0007610 74 0.071
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.071
regulation of cell communication GO:0010646 232 0.070
Fly
establishment of mitotic spindle orientation GO:0000132 10 0.070
Worm
single organism intracellular transport GO:1902582 25 0.070
regulation of catalytic activity GO:0050790 55 0.069
hemostasis GO:0007599 13 0.069
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.069
gliogenesis GO:0042063 45 0.069
defense response to other organism GO:0098542 33 0.068
b cell differentiation GO:0030183 1 0.068
blood vessel development GO:0001568 246 0.067
organic cyclic compound metabolic process GO:1901360 301 0.067
negative regulation of protein phosphorylation GO:0001933 4 0.067
regulation of synapse assembly GO:0051963 3 0.067
aging GO:0007568 2 0.067
negative regulation of signaling GO:0023057 96 0.066
regulation of protein transport GO:0051223 3 0.066
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.066
nephron epithelium development GO:0072009 16 0.065
negative regulation of biosynthetic process GO:0009890 55 0.065
regulation of mitotic cell cycle GO:0007346 25 0.064
Worm
regulation of transport GO:0051049 45 0.064
Fly
retinoic acid biosynthetic process GO:0002138 6 0.064
synapse assembly GO:0007416 9 0.063
cardiac cell fate commitment GO:0060911 1 0.063
digestive system development GO:0055123 289 0.063
Mouse Worm
regulation of cellular metabolic process GO:0031323 320 0.062
somitogenesis GO:0001756 87 0.062
adherens junction organization GO:0034332 4 0.061
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.061
regulation of stem cell proliferation GO:0072091 2 0.061
carboxylic acid biosynthetic process GO:0046394 12 0.060
negative regulation of chemotaxis GO:0050922 4 0.060
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.060
cell division GO:0051301 20 0.060
cardiac ventricle morphogenesis GO:0003208 7 0.059
negative regulation of programmed cell death GO:0043069 58 0.059
negative regulation of transcription dna templated GO:0045892 45 0.059
regulation of axon guidance GO:1902667 8 0.059
negative regulation of phosphate metabolic process GO:0045936 13 0.059
nephron tubule morphogenesis GO:0072078 1 0.059
negative regulation of epithelial cell proliferation GO:0050680 1 0.058
neuron projection guidance GO:0097485 86 0.058
tissue regeneration GO:0042246 74 0.057
muscle organ development GO:0007517 101 0.057
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.057
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.057
response to wounding GO:0009611 116 0.056
cellular response to extracellular stimulus GO:0031668 2 0.056
regulation of mitosis GO:0007088 9 0.056
terpenoid metabolic process GO:0006721 15 0.055
ectodermal placode formation GO:0060788 26 0.055
negative regulation of cellular metabolic process GO:0031324 77 0.055
diterpenoid metabolic process GO:0016101 15 0.055
single fertilization GO:0007338 3 0.054
ion homeostasis GO:0050801 41 0.054
negative regulation of metabolic process GO:0009892 86 0.054
regulation of molecular function GO:0065009 70 0.054
response to other organism GO:0051707 97 0.054
negative regulation of gastrulation GO:2000542 11 0.054
dorsal ventral neural tube patterning GO:0021904 1 0.053
response to fibroblast growth factor GO:0071774 22 0.052
meiotic cell cycle process GO:1903046 3 0.052
positive regulation of cell differentiation GO:0045597 30 0.052
epithelial cell differentiation GO:0030855 116 0.052
negative regulation of developmental process GO:0051093 65 0.051
regulation of neural precursor cell proliferation GO:2000177 3 0.051
endoderm development GO:0007492 49 0.051
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.051
skin development GO:0043588 54 0.051
protein secretion GO:0009306 1 0.050
Fly
negative regulation of protein import into nucleus GO:0042308 2 0.050
anatomical structure homeostasis GO:0060249 36 0.050
regulation of binding GO:0051098 3 0.050
regulation of primary metabolic process GO:0080090 311 0.050
glial cell differentiation GO:0010001 42 0.050
regulation of neuron projection development GO:0010975 40 0.049
regulation of heart morphogenesis GO:2000826 17 0.049
b cell activation GO:0042113 2 0.049
carboxylic acid metabolic process GO:0019752 22 0.049
macromolecule modification GO:0043412 111 0.048
positive regulation of cellular process GO:0048522 201 0.048
Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.048
embryonic limb morphogenesis GO:0030326 2 0.048
response to abiotic stimulus GO:0009628 122 0.047
growth GO:0040007 174 0.047
gene expression GO:0010467 252 0.047
positive regulation of immune effector process GO:0002699 3 0.047
cytosolic calcium ion transport GO:0060401 3 0.047
negative regulation of axonogenesis GO:0050771 7 0.046
positive regulation of biological process GO:0048518 253 0.046
Fly
midbrain hindbrain boundary development GO:0030917 23 0.046
regeneration GO:0031099 91 0.046
tube formation GO:0035148 25 0.046
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.046
inner ear receptor cell fate commitment GO:0060120 4 0.046
pancreas development GO:0031016 84 0.045
intracellular signal transduction GO:0035556 85 0.045
g protein coupled receptor signaling pathway GO:0007186 74 0.045
programmed cell death GO:0012501 119 0.045
positive regulation of striated muscle tissue development GO:0045844 1 0.045
positive regulation of molecular function GO:0044093 33 0.044
regulation of response to stress GO:0080134 36 0.044
blood coagulation GO:0007596 12 0.043
positive regulation of protein deacetylation GO:0090312 1 0.043
cellular response to chemical stimulus GO:0070887 157 0.043
neurological system process GO:0050877 62 0.043
cellular response to stress GO:0033554 62 0.043
cellular response to retinoic acid GO:0071300 1 0.043
anterior posterior pattern specification GO:0009952 152 0.043
endocardial cushion development GO:0003197 6 0.042
regulation of intracellular protein transport GO:0033157 3 0.042
Fly
positive regulation of chromatin modification GO:1903310 1 0.042
chronic inflammatory response GO:0002544 1 0.042
negative regulation of intracellular transport GO:0032387 3 0.041
negative regulation of protein kinase activity GO:0006469 4 0.041
regulation of cell activation GO:0050865 1 0.040
positive regulation of chromosome organization GO:2001252 1 0.040
macromolecular complex subunit organization GO:0043933 74 0.040
negative regulation of signal transduction GO:0009968 94 0.040
tissue remodeling GO:0048771 4 0.040
positive regulation of epithelial cell proliferation GO:0050679 1 0.040
lipid metabolic process GO:0006629 52 0.040
regulation of axon extension GO:0030516 24 0.040
regulation of cell motility GO:2000145 46 0.039
Worm
regulation of peptidase activity GO:0052547 23 0.039
metal ion homeostasis GO:0055065 26 0.039
pronephros development GO:0048793 69 0.039
regulation of protein modification process GO:0031399 29 0.039
regulation of axon extension involved in axon guidance GO:0048841 6 0.039
leukocyte proliferation GO:0070661 1 0.039
nuclear transport GO:0051169 4 0.038
regulation of cellular component organization GO:0051128 86 0.038
Worm
renal system process GO:0003014 14 0.038
signal transduction by p53 class mediator GO:0072331 13 0.038
gland development GO:0048732 143 0.038
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.038
connective tissue development GO:0061448 99 0.038
cellular protein modification process GO:0006464 100 0.037
type b pancreatic cell proliferation GO:0044342 1 0.037
cell cycle process GO:0022402 53 0.037
Worm
regulation of epithelial to mesenchymal transition GO:0010717 3 0.037
nucleocytoplasmic transport GO:0006913 4 0.037
fertilization GO:0009566 3 0.037
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.037
liver development GO:0001889 96 0.037
regulation of organ morphogenesis GO:2000027 35 0.037
neural plate development GO:0001840 10 0.036
heart valve morphogenesis GO:0003179 8 0.036
regulation of eye photoreceptor cell development GO:0042478 2 0.036
maintenance of location GO:0051235 4 0.036
embryonic organ morphogenesis GO:0048562 274 0.036
negative regulation of neurogenesis GO:0050768 20 0.035
epithelial cell development GO:0002064 42 0.035
regulation of transcription dna templated GO:0006355 213 0.035
positive regulation of cell division GO:0051781 2 0.035
response to oxygen levels GO:0070482 25 0.035
regulation of nucleic acid templated transcription GO:1903506 213 0.035
negative regulation of catenin import into nucleus GO:0035414 2 0.034
segmentation GO:0035282 97 0.034
Fly
cardiac chamber morphogenesis GO:0003206 12 0.034
regulation of cell death GO:0010941 103 0.034
endodermal cell differentiation GO:0035987 19 0.034
Worm
actin mediated cell contraction GO:0070252 1 0.034
regulation of kinase activity GO:0043549 15 0.034
modification of morphology or physiology of other organism GO:0035821 4 0.033
cellular component disassembly GO:0022411 1 0.033
endocrine pancreas development GO:0031018 27 0.033
nucleobase containing compound metabolic process GO:0006139 274 0.033
single organism nuclear import GO:1902593 3 0.033
regulation of cardiac muscle cell differentiation GO:2000725 1 0.032
cell junction organization GO:0034330 11 0.032
negative regulation of kinase activity GO:0033673 4 0.032
nuclear division GO:0000280 23 0.032
cell cycle g1 s phase transition GO:0044843 1 0.032
single organismal cell cell adhesion GO:0016337 29 0.032
negative regulation of cell death GO:0060548 60 0.032
response to vitamin GO:0033273 3 0.032
odontogenesis of dentin containing tooth GO:0042475 1 0.032
startle response GO:0001964 4 0.032
multicellular organismal macromolecule metabolic process GO:0044259 2 0.032
hypothalamus cell differentiation GO:0021979 4 0.032
mononuclear cell proliferation GO:0032943 1 0.031
membrane organization GO:0061024 21 0.031
positive regulation of cell activation GO:0050867 1 0.031
collagen metabolic process GO:0032963 2 0.031
negative regulation of mitotic cell cycle GO:0045930 11 0.030
cell cell signaling involved in cell fate commitment GO:0045168 12 0.030
circulatory system process GO:0003013 87 0.030
thalamus development GO:0021794 6 0.030
anterior head development GO:0097065 2 0.030
sensory system development GO:0048880 76 0.030
regulation of neurogenesis GO:0050767 87 0.030
positive regulation of hydrolase activity GO:0051345 13 0.030
tight junction assembly GO:0070830 1 0.030
cell cell junction organization GO:0045216 10 0.030
cell proliferation GO:0008283 80 0.030

wls disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
colon carcinoma DOID:1520 0 0.360
large intestine cancer DOID:5672 0 0.360
colon cancer DOID:219 0 0.360
gastrointestinal system cancer DOID:3119 0 0.360
intestinal cancer DOID:10155 0 0.360
cancer DOID:162 0 0.360
disease of cellular proliferation DOID:14566 0 0.360
organ system cancer DOID:0050686 0 0.360
colorectal cancer DOID:9256 0 0.360
disease of anatomical entity DOID:7 0 0.093
benign neoplasm DOID:0060072 0 0.035