Danio rerio

0 known processes

shbg

sex hormone binding globulin

(Aliases: zgc:123063,wu:fd55b08,MGC123063,shbgl,wu:fb66h07)

shbg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.569
cellular biosynthetic process GO:0044249 286 0.491
tube morphogenesis GO:0035239 349 0.464
cellular aromatic compound metabolic process GO:0006725 295 0.451
regulation of metabolic process GO:0019222 359 0.347
positive regulation of biological process GO:0048518 253 0.337
immune system process GO:0002376 241 0.325
macromolecule biosynthetic process GO:0009059 227 0.298
transcription from rna polymerase ii promoter GO:0006366 80 0.264
response to stress GO:0006950 263 0.261
cellular response to organic cyclic compound GO:0071407 38 0.246
defense response GO:0006952 47 0.239
biosynthetic process GO:0009058 294 0.238
regulation of response to stimulus GO:0048583 269 0.233
transcription dna templated GO:0006351 181 0.232
nucleic acid metabolic process GO:0090304 244 0.222
cellular macromolecule biosynthetic process GO:0034645 224 0.220
cellular response to chemical stimulus GO:0070887 157 0.217
rna metabolic process GO:0016070 219 0.204
organic cyclic compound biosynthetic process GO:1901362 223 0.200
regulation of biosynthetic process GO:0009889 250 0.195
establishment of protein localization to organelle GO:0072594 4 0.190
heterocycle metabolic process GO:0046483 290 0.189
gene expression GO:0010467 252 0.186
regulation of gene expression GO:0010468 265 0.181
regulation of nitrogen compound metabolic process GO:0051171 251 0.177
amine metabolic process GO:0009308 2 0.166
mycotoxin metabolic process GO:0043385 1 0.166
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.166
nitrogen compound metabolic process GO:0006807 319 0.160
nucleic acid templated transcription GO:0097659 181 0.156
hatching GO:0035188 4 0.155
organic substance biosynthetic process GO:1901576 289 0.153
cellular macromolecule metabolic process GO:0044260 391 0.153
digestive tract development GO:0048565 265 0.149
immune response GO:0006955 28 0.146
response to endogenous stimulus GO:0009719 83 0.145
negative regulation of biological process GO:0048519 304 0.145
single organism metabolic process GO:0044710 217 0.145
maintenance of location GO:0051235 4 0.143
organic cyclic compound metabolic process GO:1901360 301 0.133
regulation of wound healing GO:0061041 2 0.128
oxoacid metabolic process GO:0043436 31 0.118
regulation of rna metabolic process GO:0051252 224 0.116
small molecule metabolic process GO:0044281 77 0.114
circadian sleep wake cycle GO:0042745 2 0.113
regulation of nucleic acid templated transcription GO:1903506 213 0.112
response to nutrient GO:0007584 3 0.112
protein import GO:0017038 3 0.104
regulation of immune response GO:0050776 14 0.100
multicellular organism growth GO:0035264 4 0.099
response to drug GO:0042493 3 0.099
morphogenesis of an epithelium GO:0002009 333 0.099
protein localization to nucleus GO:0034504 3 0.098
regulation of macromolecule metabolic process GO:0060255 317 0.098
regulation of cellular metabolic process GO:0031323 320 0.096
signal transduction GO:0007165 455 0.096
regulation of immune system process GO:0002682 34 0.093
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.093
cellular response to lipid GO:0071396 39 0.093
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.091
heterocycle biosynthetic process GO:0018130 215 0.091
organic acid metabolic process GO:0006082 31 0.090
response to ketone GO:1901654 1 0.090
positive regulation of response to stimulus GO:0048584 80 0.090
regulation of macromolecule biosynthetic process GO:0010556 225 0.090
regulation of transcription dna templated GO:0006355 213 0.089
single organism biosynthetic process GO:0044711 71 0.086
hematopoietic or lymphoid organ development GO:0048534 191 0.085
carboxylic acid metabolic process GO:0019752 22 0.084
larval development GO:0002164 2 0.082
muscle tissue development GO:0060537 110 0.080
protein metabolic process GO:0019538 183 0.079
regulation of rna biosynthetic process GO:2001141 213 0.078
response to steroid hormone GO:0048545 35 0.078
response to chemical GO:0042221 320 0.078
regulation of protein transport GO:0051223 3 0.077
rna biosynthetic process GO:0032774 181 0.076
negative regulation of cellular process GO:0048523 283 0.074
regulation of cellular amine metabolic process GO:0033238 0 0.074
immune system development GO:0002520 191 0.073
cellular ketone metabolic process GO:0042180 11 0.068
cell surface receptor signaling pathway GO:0007166 325 0.068
cellular amine metabolic process GO:0044106 2 0.067
regulation of establishment of protein localization GO:0070201 4 0.067
striated muscle tissue development GO:0014706 110 0.066
regulation of protein import into nucleus GO:0042306 2 0.066
regulation of multicellular organism growth GO:0040014 4 0.066
response to abiotic stimulus GO:0009628 122 0.064
vasculature development GO:0001944 278 0.064
neuroblast proliferation GO:0007405 2 0.064
growth GO:0040007 174 0.063
cell proliferation GO:0008283 80 0.063
nuclear import GO:0051170 3 0.063
embryo development ending in birth or egg hatching GO:0009792 271 0.062
system process GO:0003008 185 0.062
protein import into nucleus GO:0006606 3 0.062
cellular protein metabolic process GO:0044267 129 0.062
response to organic substance GO:0010033 153 0.060
complement activation GO:0006956 3 0.060
cellular nitrogen compound metabolic process GO:0034641 290 0.059
blood circulation GO:0008015 87 0.058
cellular protein catabolic process GO:0044257 4 0.058
digestive system development GO:0055123 289 0.057
response to organic cyclic compound GO:0014070 51 0.057
cellular response to steroid hormone stimulus GO:0071383 31 0.057
regulation of cellular biosynthetic process GO:0031326 245 0.056
negative regulation of metabolic process GO:0009892 86 0.054
positive regulation of gene expression GO:0010628 71 0.054
regulation of nucleocytoplasmic transport GO:0046822 2 0.053
blood vessel development GO:0001568 246 0.053
glucose homeostasis GO:0042593 1 0.053
regulation of biological quality GO:0065008 263 0.052
regulation of multicellular organismal development GO:2000026 223 0.052
muscle structure development GO:0061061 196 0.051
regulation of protein localization to nucleus GO:1900180 2 0.051
dicarboxylic acid transport GO:0006835 1 0.051
sensory organ morphogenesis GO:0090596 200 0.051
response to lipid GO:0033993 60 0.050
developmental growth GO:0048589 166 0.049
regulation of circadian sleep wake cycle GO:0042749 1 0.049
death GO:0016265 121 0.048
regulation of primary metabolic process GO:0080090 311 0.048
regulation of multicellular organismal process GO:0051239 277 0.048
cellular response to organic substance GO:0071310 105 0.048
locomotion GO:0040011 313 0.047
response to external biotic stimulus GO:0043207 97 0.047
positive regulation of rna biosynthetic process GO:1902680 57 0.046
protein targeting to nucleus GO:0044744 3 0.046
ion transport GO:0006811 114 0.046
negative regulation of macromolecule metabolic process GO:0010605 76 0.045
organism emergence from protective structure GO:0071684 4 0.045
aflatoxin b1 metabolic process GO:0043390 1 0.045
positive regulation of rna metabolic process GO:0051254 59 0.044
regulation of intracellular protein transport GO:0033157 3 0.042
innate immune response GO:0045087 13 0.042
ether metabolic process GO:0018904 1 0.042
carbohydrate derivative metabolic process GO:1901135 61 0.041
protein modification process GO:0036211 100 0.041
regulation of molecular function GO:0065009 70 0.041
nuclear transport GO:0051169 4 0.041
lymphatic endothelial cell fate commitment GO:0060838 1 0.041
regulation of programmed cell death GO:0043067 101 0.040
intracellular estrogen receptor signaling pathway GO:0030520 3 0.040
angiogenesis GO:0001525 158 0.040
nucleobase containing compound metabolic process GO:0006139 274 0.039
blood coagulation fibrin clot formation GO:0072378 3 0.038
regulation of signal transduction GO:0009966 225 0.038
negative regulation of blood circulation GO:1903523 2 0.038
cell death GO:0008219 121 0.038
positive regulation of transport GO:0051050 2 0.038
oxidation reduction process GO:0055114 41 0.038
blood coagulation GO:0007596 12 0.037
programmed cell death GO:0012501 119 0.037
response to estrogen GO:0043627 27 0.037
regulation of cytokine production GO:0001817 3 0.037
regulation of apoptotic process GO:0042981 98 0.037
lymphocyte proliferation GO:0046651 1 0.037
regulation of cellular protein metabolic process GO:0032268 52 0.037
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.037
positive regulation of defense response GO:0031349 9 0.036
circadian sleep wake cycle process GO:0022410 2 0.036
phagocytosis GO:0006909 3 0.036
positive regulation of cellular amine metabolic process GO:0033240 0 0.035
negative regulation of cellular metabolic process GO:0031324 77 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.035
response to alkaloid GO:0043279 2 0.035
leukocyte proliferation GO:0070661 1 0.034
organonitrogen compound metabolic process GO:1901564 74 0.034
apoptotic process GO:0006915 116 0.033
cellular response to hormone stimulus GO:0032870 39 0.033
cognition GO:0050890 1 0.033
autophagy GO:0006914 4 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
cellular response to estrogen stimulus GO:0071391 24 0.032
positive regulation of transcription dna templated GO:0045893 57 0.031
sensory organ development GO:0007423 393 0.031
positive regulation of macromolecule metabolic process GO:0010604 93 0.031
regulation of hormone secretion GO:0046883 2 0.031
lipid storage GO:0019915 1 0.031
secondary metabolic process GO:0019748 3 0.030
response to hormone GO:0009725 48 0.030
negative regulation of gene expression GO:0010629 65 0.030
single organism nuclear import GO:1902593 3 0.030
proteolysis GO:0006508 38 0.029
heart development GO:0007507 313 0.029
cellular lipid metabolic process GO:0044255 36 0.029
response to xenobiotic stimulus GO:0009410 45 0.029
central nervous system development GO:0007417 387 0.029
mitochondrion organization GO:0007005 4 0.029
endothelial cell differentiation GO:0045446 20 0.028
lipid biosynthetic process GO:0008610 22 0.028
aflatoxin metabolic process GO:0046222 1 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.028
steroid metabolic process GO:0008202 7 0.028
stem cell proliferation GO:0072089 4 0.028
hemopoiesis GO:0030097 183 0.028
cellular carbohydrate metabolic process GO:0044262 4 0.028
cellular amino acid metabolic process GO:0006520 7 0.028
locomotor rhythm GO:0045475 3 0.027
regulation of cell death GO:0010941 103 0.027
regulation of protein targeting GO:1903533 2 0.027
homeostatic process GO:0042592 142 0.027
macromolecule modification GO:0043412 111 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.027
ear development GO:0043583 127 0.026
positive regulation of nucleic acid templated transcription GO:1903508 57 0.026
detection of chemical stimulus GO:0009593 4 0.026
steroid biosynthetic process GO:0006694 5 0.026
spermatid differentiation GO:0048515 2 0.026
production of molecular mediator of immune response GO:0002440 2 0.026
chordate embryonic development GO:0043009 271 0.025
digestive tract morphogenesis GO:0048546 231 0.025
regulation of protein metabolic process GO:0051246 56 0.025
photoreceptor cell differentiation GO:0046530 55 0.025
lipid homeostasis GO:0055088 3 0.025
single organism localization GO:1902578 225 0.025
regulation of inflammatory response GO:0050727 2 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
wound healing GO:0042060 90 0.025
oxalate transport GO:0019532 1 0.024
regulation of anatomical structure morphogenesis GO:0022603 130 0.024
positive regulation of cell communication GO:0010647 56 0.024
cellular response to external stimulus GO:0071496 2 0.024
peptidyl serine modification GO:0018209 2 0.024
modification dependent macromolecule catabolic process GO:0043632 3 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
regulation of innate immune response GO:0045088 11 0.024
fatty acid biosynthetic process GO:0006633 4 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.023
positive regulation of wound healing GO:0090303 1 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.023
response to light intensity GO:0009642 1 0.023
circadian sleep wake cycle sleep GO:0050802 1 0.023
response to other organism GO:0051707 97 0.022
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.022
cellular respiration GO:0045333 3 0.022
positive regulation of cytokine production GO:0001819 2 0.022
positive regulation of signaling GO:0023056 56 0.022
negative regulation of cell death GO:0060548 60 0.022
epithelial cell differentiation GO:0030855 116 0.022
negative regulation of apoptotic process GO:0043066 55 0.022
positive regulation of cellular process GO:0048522 201 0.021
cell motility GO:0048870 244 0.021
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.021
establishment of localization GO:0051234 244 0.021
regulation of blood coagulation GO:0030193 1 0.021
bmp signaling pathway GO:0030509 52 0.021
positive regulation of programmed cell death GO:0043068 29 0.021
hematopoietic stem cell migration GO:0035701 4 0.020
regulation of cell activation GO:0050865 1 0.020
positive regulation of molecular function GO:0044093 33 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
regulation of autophagy GO:0010506 3 0.020
regulation of response to stress GO:0080134 36 0.020
response to nitrogen compound GO:1901698 19 0.020
epithelial cell development GO:0002064 42 0.020
transport GO:0006810 220 0.020
generation of neurons GO:0048699 385 0.020
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.019
gastrulation GO:0007369 208 0.019
regulation of developmental process GO:0050793 247 0.019
b cell activation GO:0042113 2 0.019
post embryonic morphogenesis GO:0009886 4 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.019
development of primary female sexual characteristics GO:0046545 4 0.019
small molecule biosynthetic process GO:0044283 16 0.019
gland development GO:0048732 143 0.019
coagulation GO:0050817 13 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
sleep GO:0030431 1 0.019
type b pancreatic cell development GO:0003323 4 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.018
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.018
lipid catabolic process GO:0016042 4 0.018
muscle cell development GO:0055001 115 0.018
transcription from rna polymerase iii promoter GO:0006383 1 0.018
peripheral nervous system development GO:0007422 55 0.018
mononuclear cell proliferation GO:0032943 1 0.018
negative regulation of biosynthetic process GO:0009890 55 0.017
regulation of body fluid levels GO:0050878 16 0.017
localization of cell GO:0051674 244 0.017
epithelial tube morphogenesis GO:0060562 148 0.017
carbohydrate biosynthetic process GO:0016051 1 0.017
negative regulation of immune response GO:0050777 2 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
negative regulation of signaling GO:0023057 96 0.017
regionalization GO:0003002 274 0.017
cardiocyte differentiation GO:0035051 44 0.017
eye morphogenesis GO:0048592 144 0.017
positive regulation of secretion GO:0051047 1 0.017
heart process GO:0003015 71 0.017
response to wounding GO:0009611 116 0.017
macromolecule localization GO:0033036 54 0.016
muscle organ development GO:0007517 101 0.016
response to monosaccharide GO:0034284 3 0.016
immune effector process GO:0002252 23 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
regulation of reproductive process GO:2000241 4 0.016
endothelial cell fate commitment GO:0060839 3 0.016
regulation of defense response GO:0031347 14 0.016
meiotic nuclear division GO:0007126 4 0.016
neurotransmitter secretion GO:0007269 2 0.015
regulation of hemostasis GO:1900046 1 0.015
positive regulation of cell activation GO:0050867 1 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
cellular response to xenobiotic stimulus GO:0071466 35 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
regulation of protein complex assembly GO:0043254 3 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.015
cellular component biogenesis GO:0044085 178 0.015
regulation of catalytic activity GO:0050790 55 0.015
muscle cell differentiation GO:0042692 139 0.015
lymphatic endothelial cell differentiation GO:0060836 1 0.015
embryonic skeletal joint morphogenesis GO:0060272 3 0.015
carbohydrate homeostasis GO:0033500 1 0.015
response to biotic stimulus GO:0009607 97 0.015
regulation of signaling GO:0023051 235 0.015
negative regulation of defense response GO:0031348 2 0.015
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.015
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
embryonic skeletal joint development GO:0072498 3 0.014
ear morphogenesis GO:0042471 64 0.014
response to carbohydrate GO:0009743 3 0.014
cellular component morphogenesis GO:0032989 336 0.014
single organism transport GO:0044765 206 0.014
extracellular matrix organization GO:0030198 27 0.014
multi organism process GO:0051704 134 0.014
skeletal system morphogenesis GO:0048705 102 0.014
organic substance transport GO:0071702 58 0.014
cellular response to endogenous stimulus GO:0071495 68 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
cellular response to oxygen containing compound GO:1901701 20 0.013
phosphorus metabolic process GO:0006793 109 0.013
foregut morphogenesis GO:0007440 4 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
regulation of circadian rhythm GO:0042752 4 0.013
extracellular structure organization GO:0043062 27 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
single organism carbohydrate metabolic process GO:0044723 12 0.013
cellular protein modification process GO:0006464 100 0.013
regulation of dna replication GO:0006275 3 0.013
heart contraction GO:0060047 71 0.013
membrane invagination GO:0010324 1 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
liver development GO:0001889 96 0.013
activation of mapk activity GO:0000187 3 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
activation of immune response GO:0002253 9 0.012
biological adhesion GO:0022610 40 0.012
cation homeostasis GO:0055080 33 0.012
female sex differentiation GO:0046660 4 0.012
regulation of intracellular ph GO:0051453 1 0.012
nitrogen compound transport GO:0071705 23 0.012
peptide transport GO:0015833 1 0.012
leukocyte homeostasis GO:0001776 2 0.012
negative regulation of cellular biosynthetic process GO:0031327 55 0.012
muscle system process GO:0003012 20 0.012
cell substrate adhesion GO:0031589 4 0.012
circulatory system process GO:0003013 87 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
post embryonic foregut morphogenesis GO:0048618 3 0.011
regulation of protein catabolic process GO:0042176 1 0.011
acylglycerol homeostasis GO:0055090 2 0.011
regulation of cell communication GO:0010646 232 0.011
regulation of localization GO:0032879 104 0.011
tissue remodeling GO:0048771 4 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
regulation of coagulation GO:0050818 2 0.011
embryonic hemopoiesis GO:0035162 53 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
positive regulation of apoptotic process GO:0043065 29 0.011
regulation of cell development GO:0060284 100 0.011
response to amphetamine GO:0001975 1 0.011
cellular component movement GO:0006928 335 0.011
cellular response to starvation GO:0009267 1 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
eye development GO:0001654 277 0.011
response to temperature stimulus GO:0009266 15 0.011
response to bacterium GO:0009617 58 0.011
carbohydrate metabolic process GO:0005975 12 0.011
eye photoreceptor cell differentiation GO:0001754 45 0.011
positive regulation of jak stat cascade GO:0046427 2 0.010
striated muscle cell development GO:0055002 108 0.010
developmental maturation GO:0021700 34 0.010
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.010
hepaticobiliary system development GO:0061008 98 0.010
positive regulation of biosynthetic process GO:0009891 68 0.010

shbg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.280
nervous system disease DOID:863 0 0.060
immune system disease DOID:2914 0 0.029
retinal disease DOID:5679 0 0.016
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
integumentary system disease DOID:16 0 0.016
disease of cellular proliferation DOID:14566 0 0.013