Danio rerio

0 known processes

nup98

nucleoporin 98

(Aliases: MGC173990,im:7151238,zgc:113968,zgc:63593,MGC63593)

nup98 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.095
meiotic nuclear division GO:0007126 4 0.054
nuclear transport GO:0051169 4 0.052
aging GO:0007568 2 0.047
positive regulation of transport GO:0051050 2 0.045
regulation of protein catabolic process GO:0042176 1 0.044
response to drug GO:0042493 3 0.042
cellular macromolecule metabolic process GO:0044260 391 0.041
nucleocytoplasmic transport GO:0006913 4 0.040
cellular nitrogen compound metabolic process GO:0034641 290 0.040
signal transduction GO:0007165 455 0.039
regulation of gene expression GO:0010468 265 0.038
nucleic acid templated transcription GO:0097659 181 0.038
regulation of cellular metabolic process GO:0031323 320 0.038
positive regulation of cellular catabolic process GO:0031331 3 0.036
organic substance biosynthetic process GO:1901576 289 0.034
embryonic organ development GO:0048568 381 0.034
positive regulation of catabolic process GO:0009896 4 0.034
gene expression GO:0010467 252 0.033
protein import GO:0017038 3 0.033
regulation of nitrogen compound metabolic process GO:0051171 251 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.032
rna metabolic process GO:0016070 219 0.032
maintenance of location GO:0051235 4 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.031
regulation of macromolecule metabolic process GO:0060255 317 0.031
cellular macromolecule biosynthetic process GO:0034645 224 0.031
transport GO:0006810 220 0.031
heterocycle metabolic process GO:0046483 290 0.031
cellular biosynthetic process GO:0044249 286 0.030
amine metabolic process GO:0009308 2 0.030
regulation of protein transport GO:0051223 3 0.030
biosynthetic process GO:0009058 294 0.030
cellular amine metabolic process GO:0044106 2 0.030
lipid storage GO:0019915 1 0.030
establishment of localization GO:0051234 244 0.030
response to stress GO:0006950 263 0.029
locomotion GO:0040011 313 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
organic cyclic compound metabolic process GO:1901360 301 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
single organism nuclear import GO:1902593 3 0.029
regulation of metabolic process GO:0019222 359 0.029
regulation of biosynthetic process GO:0009889 250 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
positive regulation of cell cycle GO:0045787 3 0.028
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
protein localization to nucleus GO:0034504 3 0.028
cellular component disassembly GO:0022411 1 0.028
mitochondrion organization GO:0007005 4 0.028
nucleic acid metabolic process GO:0090304 244 0.028
heterocycle biosynthetic process GO:0018130 215 0.028
cellular response to external stimulus GO:0071496 2 0.028
single organism localization GO:1902578 225 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
regulation of rna metabolic process GO:0051252 224 0.027
embryonic organ morphogenesis GO:0048562 274 0.027
proteasomal protein catabolic process GO:0010498 2 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
cellular component morphogenesis GO:0032989 336 0.027
g1 s transition of mitotic cell cycle GO:0000082 1 0.027
regulation of primary metabolic process GO:0080090 311 0.027
regulation of cytokine production GO:0001817 3 0.027
cellular protein catabolic process GO:0044257 4 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
cellular component movement GO:0006928 335 0.026
phagocytosis GO:0006909 3 0.026
cellular ketone metabolic process GO:0042180 11 0.026
regulation of signal transduction GO:0009966 225 0.026
aromatic compound biosynthetic process GO:0019438 217 0.026
nucleobase containing compound metabolic process GO:0006139 274 0.026
meiotic cell cycle process GO:1903046 3 0.026
cellular nitrogen compound biosynthetic process GO:0044271 218 0.026
protein metabolic process GO:0019538 183 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
nuclear import GO:0051170 3 0.025
cellular response to nutrient levels GO:0031669 2 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.025
regulation of biological quality GO:0065008 263 0.024
regulation of binding GO:0051098 3 0.024
negative regulation of biological process GO:0048519 304 0.024
regulation of protein complex assembly GO:0043254 3 0.024
protein import into nucleus GO:0006606 3 0.024
modification dependent macromolecule catabolic process GO:0043632 3 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
regulation of cellular biosynthetic process GO:0031326 245 0.023
positive regulation of biological process GO:0048518 253 0.023
rna biosynthetic process GO:0032774 181 0.023
organelle organization GO:0006996 227 0.023
cell cycle g1 s phase transition GO:0044843 1 0.023
digestive system development GO:0055123 289 0.023
regulation of protein targeting GO:1903533 2 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
autophagy GO:0006914 4 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
single organism organelle organization GO:1902589 199 0.023
response to carbohydrate GO:0009743 3 0.023
response to external stimulus GO:0009605 264 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
single organism transport GO:0044765 206 0.023
protein targeting to nucleus GO:0044744 3 0.022
regulation of response to stimulus GO:0048583 269 0.022
regulation of mrna processing GO:0050684 3 0.022
cell part morphogenesis GO:0032990 246 0.022
transcription dna templated GO:0006351 181 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
regulation of intracellular protein transport GO:0033157 3 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
regulation of transcription dna templated GO:0006355 213 0.021
regulation of cell shape GO:0008360 1 0.021
regulation of nucleic acid templated transcription GO:1903506 213 0.021
cell projection organization GO:0030030 284 0.021
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
nuclear export GO:0051168 1 0.020
homeostatic process GO:0042592 142 0.020
protein acetylation GO:0006473 2 0.020
protein polyubiquitination GO:0000209 4 0.020
cell motility GO:0048870 244 0.020
response to chemical GO:0042221 320 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
cytokinesis GO:0000910 3 0.020
regulation of protein localization to nucleus GO:1900180 2 0.020
meiosis i GO:0007127 1 0.019
gtp metabolic process GO:0046039 4 0.019
cell migration GO:0016477 237 0.019
mitotic dna integrity checkpoint GO:0044774 4 0.019
cell morphogenesis GO:0000902 289 0.019
oxoacid metabolic process GO:0043436 31 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
localization of cell GO:0051674 244 0.019
positive regulation of cytokine production GO:0001819 2 0.019
single organism metabolic process GO:0044710 217 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
tube morphogenesis GO:0035239 349 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
cell projection morphogenesis GO:0048858 244 0.019
regulation of cell activation GO:0050865 1 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
stem cell maintenance GO:0019827 4 0.019
digestive tract morphogenesis GO:0048546 231 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
heart development GO:0007507 313 0.019
cellular protein metabolic process GO:0044267 129 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
protein polymerization GO:0051258 4 0.018
gtp catabolic process GO:0006184 2 0.018
regulation of cellular protein catabolic process GO:1903362 1 0.018
response to uv GO:0009411 3 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
positive regulation of cellular process GO:0048522 201 0.018
regulation of developmental process GO:0050793 247 0.018
generation of neurons GO:0048699 385 0.018
organic acid metabolic process GO:0006082 31 0.018
negative regulation of cellular process GO:0048523 283 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
cellular carbohydrate metabolic process GO:0044262 4 0.018
multicellular organism growth GO:0035264 4 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
immune system process GO:0002376 241 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
guanosine containing compound metabolic process GO:1901068 4 0.017
meiotic chromosome segregation GO:0045132 3 0.017
regulation of cell communication GO:0010646 232 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
central nervous system development GO:0007417 387 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
blood circulation GO:0008015 87 0.017
eye development GO:0001654 277 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
cognition GO:0050890 1 0.017
mitotic dna damage checkpoint GO:0044773 4 0.017
positive regulation of metabolic process GO:0009893 108 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
peptide transport GO:0015833 1 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
macromolecule modification GO:0043412 111 0.017
lamellipodium organization GO:0097581 1 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
protein stabilization GO:0050821 2 0.017
centrosome organization GO:0051297 1 0.017
circulatory system process GO:0003013 87 0.017
actin polymerization or depolymerization GO:0008154 2 0.016
response to monosaccharide GO:0034284 3 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
positive regulation of secretion GO:0051047 1 0.016
ameboidal type cell migration GO:0001667 143 0.016
cellular response to starvation GO:0009267 1 0.016
developmental programmed cell death GO:0010623 4 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
response to hexose GO:0009746 3 0.016
cellular component biogenesis GO:0044085 178 0.016
membrane invagination GO:0010324 1 0.016
spindle assembly GO:0051225 2 0.016
cellular protein modification process GO:0006464 100 0.016
system process GO:0003008 185 0.016
microtubule organizing center organization GO:0031023 1 0.016
head development GO:0060322 303 0.016
phosphatidylinositol mediated signaling GO:0048015 2 0.016
protein secretion GO:0009306 1 0.015
small molecule metabolic process GO:0044281 77 0.015
stem cell division GO:0017145 1 0.015
muscle structure development GO:0061061 196 0.015
gastrulation GO:0007369 208 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
adherens junction organization GO:0034332 4 0.015
cellular component assembly GO:0022607 170 0.015
response to glucose GO:0009749 3 0.015
sensory organ development GO:0007423 393 0.015
neuron differentiation GO:0030182 353 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
response to nutrient GO:0007584 3 0.015
immune system development GO:0002520 191 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
phagocytosis engulfment GO:0006911 1 0.015
protein acylation GO:0043543 3 0.015
lamellipodium assembly GO:0030032 1 0.014
negative regulation of metabolic process GO:0009892 86 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
leukocyte proliferation GO:0070661 1 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
double strand break repair GO:0006302 3 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
cellular response to light stimulus GO:0071482 4 0.014
positive regulation of cell activation GO:0050867 1 0.014
growth GO:0040007 174 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
regulation of muscle contraction GO:0006937 3 0.014
regulation of blood pressure GO:0008217 1 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
digestive tract development GO:0048565 265 0.014
regulation of response to biotic stimulus GO:0002831 2 0.014
atp catabolic process GO:0006200 4 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
neuron development GO:0048666 262 0.014
protein modification process GO:0036211 100 0.014
lipid homeostasis GO:0055088 3 0.014
stem cell proliferation GO:0072089 4 0.014
endosomal transport GO:0016197 2 0.014
regulation of gtpase activity GO:0043087 2 0.013
regulation of tube size GO:0035150 2 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
regulation of signaling GO:0023051 235 0.013
dna templated transcription elongation GO:0006354 3 0.013
regulation of protein polymerization GO:0032271 2 0.013
single fertilization GO:0007338 3 0.013
regulation of inflammatory response GO:0050727 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
intracellular signal transduction GO:0035556 85 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
response to organic substance GO:0010033 153 0.013
lateral line system development GO:0048925 76 0.013
protein complex disassembly GO:0043241 1 0.013
organelle assembly GO:0070925 110 0.013
female sex differentiation GO:0046660 4 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
heart process GO:0003015 71 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
heart contraction GO:0060047 71 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
sensory organ morphogenesis GO:0090596 200 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
regionalization GO:0003002 274 0.013
spermatid development GO:0007286 2 0.013
chemosensory behavior GO:0007635 1 0.013
membrane fusion GO:0061025 2 0.013
rna localization GO:0006403 4 0.013
alternative mrna splicing via spliceosome GO:0000380 1 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
cellular response to radiation GO:0071478 4 0.012
fertilization GO:0009566 3 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
mitotic recombination GO:0006312 2 0.012
negative regulation of defense response GO:0031348 2 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
female gonad development GO:0008585 4 0.012
regulation of synapse organization GO:0050807 3 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
macromolecular complex disassembly GO:0032984 1 0.012
neuron projection development GO:0031175 180 0.012
negative regulation of cytokine production GO:0001818 1 0.012
vasculature development GO:0001944 278 0.012
regulation of localization GO:0032879 104 0.012
startle response GO:0001964 4 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
cell death GO:0008219 121 0.012
negative regulation of signaling GO:0023057 96 0.012
peptidyl serine modification GO:0018209 2 0.012
response to corticosteroid GO:0031960 1 0.012
spermatid differentiation GO:0048515 2 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
death GO:0016265 121 0.012
cellular localization GO:0051641 97 0.012
cellular response to oxygen levels GO:0071453 1 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
programmed cell death GO:0012501 119 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
interspecies interaction between organisms GO:0044419 4 0.012
telomere organization GO:0032200 1 0.012
establishment of localization in cell GO:0051649 77 0.012
regulation of cell death GO:0010941 103 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
adult behavior GO:0030534 2 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
actin filament polymerization GO:0030041 2 0.011
cell matrix adhesion GO:0007160 4 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
negative regulation of kinase activity GO:0033673 4 0.011
negative regulation of signal transduction GO:0009968 94 0.011
negative regulation of cell communication GO:0010648 96 0.011
response to vitamin GO:0033273 3 0.011
regulation of circadian rhythm GO:0042752 4 0.011
hemopoiesis GO:0030097 183 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
blood vessel development GO:0001568 246 0.011
mononuclear cell proliferation GO:0032943 1 0.011
g2 dna damage checkpoint GO:0031572 3 0.011
regulation of wound healing GO:0061041 2 0.011
chordate embryonic development GO:0043009 271 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
muscle cell development GO:0055001 115 0.011
compound eye development GO:0048749 2 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
multi organism process GO:0051704 134 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
negative regulation of gene expression GO:0010629 65 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
response to topologically incorrect protein GO:0035966 2 0.011
regulation of organ growth GO:0046620 3 0.011
lymphocyte proliferation GO:0046651 1 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
specification of symmetry GO:0009799 204 0.011
kidney development GO:0001822 92 0.011
mitotic g2 m transition checkpoint GO:0044818 3 0.010
regulation of reproductive process GO:2000241 4 0.010
cell substrate adhesion GO:0031589 4 0.010
cellular response to organic substance GO:0071310 105 0.010
response to ketone GO:1901654 1 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
organelle fusion GO:0048284 3 0.010
nucleic acid transport GO:0050657 2 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
muscle cell differentiation GO:0042692 139 0.010
protein complex localization GO:0031503 1 0.010
carbohydrate homeostasis GO:0033500 1 0.010
regulation of cellular component movement GO:0051270 55 0.010
regulation of metal ion transport GO:0010959 4 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
myeloid cell differentiation GO:0030099 86 0.010
regulation of rho protein signal transduction GO:0035023 2 0.010
regulation of blood vessel size GO:0050880 2 0.010
secondary metabolic process GO:0019748 3 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
cytoskeleton organization GO:0007010 96 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
multi organism cellular process GO:0044764 2 0.010
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.010
protein localization to plasma membrane GO:0072659 1 0.010
mitotic cell cycle GO:0000278 64 0.010
glial cell migration GO:0008347 3 0.010
positive regulation of dna templated transcription elongation GO:0032786 1 0.010
centrosome cycle GO:0007098 1 0.010
developmental growth GO:0048589 166 0.010

nup98 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.023
musculoskeletal system disease DOID:17 0 0.018
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.016
muscular disease DOID:0080000 0 0.016
muscle tissue disease DOID:66 0 0.016
myopathy DOID:423 0 0.014
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
eye and adnexa disease DOID:1492 0 0.010
sensory system disease DOID:0050155 0 0.010