Danio rerio

0 known processes

slc1a3a

solute carrier family 1 (glial high affinity glutamate transporter), member 3a

(Aliases: zgc:77768,zgc:56661,wu:fd50b05,wu:fb98e05,slc1a3)

slc1a3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.633
heart development GO:0007507 313 0.309
growth GO:0040007 174 0.230
aging GO:0007568 2 0.223
regionalization GO:0003002 274 0.217
tube morphogenesis GO:0035239 349 0.196
biosynthetic process GO:0009058 294 0.184
Mouse
locomotion GO:0040011 313 0.170
signal transduction GO:0007165 455 0.169
organic substance biosynthetic process GO:1901576 289 0.158
Mouse
cellular component movement GO:0006928 335 0.136
chordate embryonic development GO:0043009 271 0.132
establishment of localization GO:0051234 244 0.120
Human Mouse
regulation of signaling GO:0023051 235 0.119
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.117
morphogenesis of an epithelium GO:0002009 333 0.108
regulation of biosynthetic process GO:0009889 250 0.106
intracellular signal transduction GO:0035556 85 0.102
single organism metabolic process GO:0044710 217 0.097
Mouse
regulation of multicellular organism growth GO:0040014 4 0.092
central nervous system development GO:0007417 387 0.091
cellular protein metabolic process GO:0044267 129 0.090
cellular biosynthetic process GO:0044249 286 0.088
Mouse
digestive tract morphogenesis GO:0048546 231 0.084
cellular macromolecule metabolic process GO:0044260 391 0.082
cellular ketone metabolic process GO:0042180 11 0.079
determination of left right symmetry GO:0007368 179 0.079
regulation of metabolic process GO:0019222 359 0.079
response to stress GO:0006950 263 0.079
Mouse
neuron projection development GO:0031175 180 0.077
cell projection organization GO:0030030 284 0.077
small molecule metabolic process GO:0044281 77 0.076
Mouse
heterocycle biosynthetic process GO:0018130 215 0.076
organic acid metabolic process GO:0006082 31 0.072
Mouse
protein metabolic process GO:0019538 183 0.072
gastrulation GO:0007369 208 0.071
cellular amine metabolic process GO:0044106 2 0.071
macromolecule biosynthetic process GO:0009059 227 0.068
vasculature development GO:0001944 278 0.068
regulation of cellular ketone metabolic process GO:0010565 7 0.066
eye development GO:0001654 277 0.064
response to external stimulus GO:0009605 264 0.062
Mouse
lipid storage GO:0019915 1 0.062
head development GO:0060322 303 0.061
digestive system development GO:0055123 289 0.061
regulation of response to stimulus GO:0048583 269 0.060
regulation of cell communication GO:0010646 232 0.060
Mouse
wound healing GO:0042060 90 0.059
cellular nitrogen compound biosynthetic process GO:0044271 218 0.059
macromolecule modification GO:0043412 111 0.059
synaptic growth at neuromuscular junction GO:0051124 2 0.058
cell part morphogenesis GO:0032990 246 0.058
specification of symmetry GO:0009799 204 0.058
single organism transport GO:0044765 206 0.058
Human Mouse
negative regulation of cellular process GO:0048523 283 0.058
determination of heart left right asymmetry GO:0061371 117 0.057
negative regulation of biological process GO:0048519 304 0.057
regulation of cellular metabolic process GO:0031323 320 0.057
gamete generation GO:0007276 33 0.056
amine metabolic process GO:0009308 2 0.056
protein modification process GO:0036211 100 0.056
single organism localization GO:1902578 225 0.056
Human Mouse
cellular response to external stimulus GO:0071496 2 0.054
gtp metabolic process GO:0046039 4 0.053
cellular protein modification process GO:0006464 100 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.052
regulation of cellular amine metabolic process GO:0033238 0 0.050
cell migration GO:0016477 237 0.050
adult behavior GO:0030534 2 0.050
regulation of cellular amino acid metabolic process GO:0006521 0 0.049
positive regulation of notch signaling pathway GO:0045747 3 0.049
organic cyclic compound biosynthetic process GO:1901362 223 0.048
digestive tract development GO:0048565 265 0.048
multicellular organism growth GO:0035264 4 0.047
sensory organ morphogenesis GO:0090596 200 0.047
phosphate containing compound metabolic process GO:0006796 108 0.047
response to wounding GO:0009611 116 0.046
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.046
nerve development GO:0021675 45 0.046
Mouse
astrocyte differentiation GO:0048708 1 0.046
cell cycle g1 s phase transition GO:0044843 1 0.044
oxoacid metabolic process GO:0043436 31 0.044
Mouse
determination of bilateral symmetry GO:0009855 204 0.043
neuron projection morphogenesis GO:0048812 161 0.043
phosphorus metabolic process GO:0006793 109 0.043
regulation of nitrogen compound metabolic process GO:0051171 251 0.042
developmental growth GO:0048589 166 0.042
sensory system development GO:0048880 76 0.042
regeneration GO:0031099 91 0.042
g1 s transition of mitotic cell cycle GO:0000082 1 0.042
neurological system process GO:0050877 62 0.042
Mouse
glucose homeostasis GO:0042593 1 0.042
lateral line development GO:0048882 66 0.041
cell surface receptor signaling pathway GO:0007166 325 0.041
heart morphogenesis GO:0003007 156 0.040
brain development GO:0007420 293 0.040
gene expression GO:0010467 252 0.040
positive regulation of cell cycle GO:0045787 3 0.039
cell morphogenesis GO:0000902 289 0.039
Mouse
carboxylic acid metabolic process GO:0019752 22 0.039
Mouse
response to chemical GO:0042221 320 0.038
Mouse
single organism nuclear import GO:1902593 3 0.037
glial cell migration GO:0008347 3 0.037
regulation of signal transduction GO:0009966 225 0.036
cellular component morphogenesis GO:0032989 336 0.036
Mouse
phagocytosis GO:0006909 3 0.036
embryonic organ development GO:0048568 381 0.036
regulation of carbohydrate metabolic process GO:0006109 4 0.036
nitrogen compound metabolic process GO:0006807 319 0.036
Mouse
response to organic substance GO:0010033 153 0.036
regulation of translational initiation GO:0006446 1 0.036
positive regulation of cellular amine metabolic process GO:0033240 0 0.036
response to organic cyclic compound GO:0014070 51 0.034
action potential GO:0001508 19 0.034
positive regulation of catabolic process GO:0009896 4 0.034
guanosine containing compound metabolic process GO:1901068 4 0.034
cell projection morphogenesis GO:0048858 244 0.034
neuronal action potential GO:0019228 18 0.034
cilium morphogenesis GO:0060271 85 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.033
localization of cell GO:0051674 244 0.033
regulation of wound healing GO:0061041 2 0.032
transmission of nerve impulse GO:0019226 19 0.032
sensory organ development GO:0007423 393 0.032
embryonic heart tube morphogenesis GO:0003143 108 0.032
protein import into nucleus GO:0006606 3 0.031
positive regulation of wound healing GO:0090303 1 0.031
positive regulation of nucleoside metabolic process GO:0045979 1 0.031
generation of neurons GO:0048699 385 0.031
Mouse
neuron differentiation GO:0030182 353 0.031
Mouse
blood vessel development GO:0001568 246 0.031
maintenance of location GO:0051235 4 0.031
cellular component assembly GO:0022607 170 0.030
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.030
transcription from rna polymerase iii promoter GO:0006383 1 0.030
response to nutrient GO:0007584 3 0.030
cell motility GO:0048870 244 0.030
hematopoietic or lymphoid organ development GO:0048534 191 0.030
heterocycle metabolic process GO:0046483 290 0.030
regulation of multicellular organismal process GO:0051239 277 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.030
regulation of primary metabolic process GO:0080090 311 0.030
regulation of jak stat cascade GO:0046425 3 0.030
nuclear import GO:0051170 3 0.030
cell migration involved in heart development GO:0060973 22 0.030
epithelial tube morphogenesis GO:0060562 148 0.029
cellular response to extracellular stimulus GO:0031668 2 0.029
regulation of protein transport GO:0051223 3 0.028
single organism biosynthetic process GO:0044711 71 0.028
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.028
regulation of cellular biosynthetic process GO:0031326 245 0.028
mesenchymal cell development GO:0014031 78 0.028
positive regulation of gtp catabolic process GO:0033126 1 0.028
mesenchymal cell differentiation GO:0048762 87 0.028
neurotransmitter transport GO:0006836 2 0.028
cellular amino acid metabolic process GO:0006520 7 0.028
Mouse
compound eye development GO:0048749 2 0.028
gtp catabolic process GO:0006184 2 0.028
neuromast development GO:0048884 46 0.027
leukocyte proliferation GO:0070661 1 0.027
dorsal ventral pattern formation GO:0009953 125 0.027
apoptotic process GO:0006915 116 0.027
positive regulation of cellular metabolic process GO:0031325 94 0.027
programmed cell death GO:0012501 119 0.027
neuron development GO:0048666 262 0.027
Mouse
hemopoiesis GO:0030097 183 0.027
hepaticobiliary system development GO:0061008 98 0.026
mesenchyme development GO:0060485 127 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
axonogenesis GO:0007409 152 0.026
nephron morphogenesis GO:0072028 2 0.026
pancreas development GO:0031016 84 0.025
multi organism process GO:0051704 134 0.025
transport GO:0006810 220 0.025
Human Mouse
gliogenesis GO:0042063 45 0.025
fatty acid oxidation GO:0019395 1 0.025
regulation of gtpase activity GO:0043087 2 0.025
cellular nitrogen compound metabolic process GO:0034641 290 0.024
positive regulation of transport GO:0051050 2 0.024
muscle cell differentiation GO:0042692 139 0.024
neural crest cell differentiation GO:0014033 72 0.024
positive regulation of map kinase activity GO:0043406 3 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.023
cilium assembly GO:0042384 58 0.023
gland development GO:0048732 143 0.023
camera type eye development GO:0043010 222 0.023
translational initiation GO:0006413 3 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
response to abiotic stimulus GO:0009628 122 0.023
Mouse
meiotic nuclear division GO:0007126 4 0.023
cell cycle GO:0007049 93 0.023
regulation of developmental process GO:0050793 247 0.022
negative regulation of signal transduction GO:0009968 94 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
rna biosynthetic process GO:0032774 181 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
Mouse
immune system development GO:0002520 191 0.022
regulation of fatty acid metabolic process GO:0019217 1 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
cellular response to nutrient levels GO:0031669 2 0.022
regulation of biological quality GO:0065008 263 0.022
angiogenesis GO:0001525 158 0.022
macromolecular complex assembly GO:0065003 35 0.021
neuron projection guidance GO:0097485 86 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
reproductive process GO:0022414 40 0.021
multicellular organismal signaling GO:0035637 22 0.021
cognition GO:0050890 1 0.021
regulation of membrane potential GO:0042391 23 0.020
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.020
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
cellular modified amino acid metabolic process GO:0006575 3 0.020
protein import GO:0017038 3 0.020
response to light stimulus GO:0009416 46 0.020
Mouse
regulation of nervous system development GO:0051960 90 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.020
posterior lateral line development GO:0048916 38 0.020
epithelial cell differentiation GO:0030855 116 0.020
response to endogenous stimulus GO:0009719 83 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
negative regulation of epithelial cell migration GO:0010633 1 0.020
cellular response to endogenous stimulus GO:0071495 68 0.020
mitochondrion organization GO:0007005 4 0.019
rna localization GO:0006403 4 0.019
peptidyl serine phosphorylation GO:0018105 1 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
cilium organization GO:0044782 71 0.019
cellular response to stress GO:0033554 62 0.019
lymphocyte proliferation GO:0046651 1 0.019
somite development GO:0061053 96 0.018
regulation of glial cell differentiation GO:0045685 4 0.018
regulation of response to extracellular stimulus GO:0032104 1 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
glial cell proliferation GO:0014009 4 0.018
positive regulation of jak stat cascade GO:0046427 2 0.018
lymphatic endothelial cell differentiation GO:0060836 1 0.018
negative regulation of response to stimulus GO:0048585 104 0.018
regulation of programmed cell death GO:0043067 101 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
developmental maturation GO:0021700 34 0.017
system process GO:0003008 185 0.017
Mouse
regulation of circadian rhythm GO:0042752 4 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
vesicle mediated transport GO:0016192 22 0.017
actin filament based movement GO:0030048 1 0.017
embryonic skeletal system morphogenesis GO:0048704 93 0.017
mesoderm development GO:0007498 88 0.017
tor signaling GO:0031929 7 0.017
regulation of cell activation GO:0050865 1 0.017
jak stat cascade GO:0007259 5 0.017
fin regeneration GO:0031101 51 0.017
tissue regeneration GO:0042246 74 0.017
cellular component biogenesis GO:0044085 178 0.017
carbohydrate homeostasis GO:0033500 1 0.017
regulation of protein targeting GO:1903533 2 0.017
axon development GO:0061564 166 0.017
endothelial cell fate commitment GO:0060839 3 0.016
positive regulation of response to stimulus GO:0048584 80 0.016
translation GO:0006412 5 0.016
single organism organelle organization GO:1902589 199 0.016
regulation of phosphate metabolic process GO:0019220 43 0.016
negative regulation of dna replication GO:0008156 2 0.016
cellular response to organic substance GO:0071310 105 0.016
inner ear morphogenesis GO:0042472 63 0.016
stem cell maintenance GO:0019827 4 0.016
protein phosphorylation GO:0006468 47 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
nucleic acid metabolic process GO:0090304 244 0.016
blood vessel morphogenesis GO:0048514 216 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
liver development GO:0001889 96 0.016
interspecies interaction between organisms GO:0044419 4 0.016
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
regulation of dna replication GO:0006275 3 0.015
positive regulation of gliogenesis GO:0014015 2 0.015
ameboidal type cell migration GO:0001667 143 0.015
cellular response to starvation GO:0009267 1 0.015
organ regeneration GO:0031100 1 0.015
protein targeting to nucleus GO:0044744 3 0.015
regulation of gene expression GO:0010468 265 0.015
single organism reproductive process GO:0044702 40 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
stem cell proliferation GO:0072089 4 0.015
regulation of localization GO:0032879 104 0.015
axon ensheathment GO:0008366 18 0.015
embryonic heart tube development GO:0035050 133 0.015
death GO:0016265 121 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
phosphorylation GO:0016310 69 0.015
response to metal ion GO:0010038 34 0.014
nucleic acid templated transcription GO:0097659 181 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
cranial nerve development GO:0021545 42 0.014
Mouse
eye morphogenesis GO:0048592 144 0.014
startle response GO:0001964 4 0.014
nephron tubule morphogenesis GO:0072078 1 0.014
endocytosis GO:0006897 16 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
regulation of synapse assembly GO:0051963 3 0.014
cellular localization GO:0051641 97 0.014
regulation of cytokine production GO:0001817 3 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
long chain fatty acid metabolic process GO:0001676 1 0.013
positive regulation of signaling GO:0023056 56 0.013
Mouse
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
muscle tissue development GO:0060537 110 0.013
heart looping GO:0001947 94 0.013
rna metabolic process GO:0016070 219 0.013
regulation of cell cycle GO:0051726 52 0.013
positive regulation of metabolic process GO:0009893 108 0.013
rna transport GO:0050658 2 0.013
cell death GO:0008219 121 0.013
renal tubule morphogenesis GO:0061333 1 0.013
cell fate specification GO:0001708 68 0.013
response to glucocorticoid GO:0051384 1 0.013
positive regulation of phosphorus metabolic process GO:0010562 21 0.013
response to vitamin GO:0033273 3 0.013
negative regulation of catabolic process GO:0009895 3 0.013
cell cell recognition GO:0009988 1 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
positive regulation of signal transduction GO:0009967 56 0.013
muscle structure development GO:0061061 196 0.013
negative regulation of endothelial cell migration GO:0010596 1 0.012
regulation of synapse organization GO:0050807 3 0.012
regulation of cell shape GO:0008360 1 0.012
lipid catabolic process GO:0016042 4 0.012
response to oxygen containing compound GO:1901700 55 0.012
alcohol biosynthetic process GO:0046165 2 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
immune system process GO:0002376 241 0.012
mononuclear cell proliferation GO:0032943 1 0.012
cell fate commitment GO:0045165 99 0.012
mechanosensory lateral line system development GO:0048881 49 0.012
sensory perception of mechanical stimulus GO:0050954 16 0.012
Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
striated muscle cell differentiation GO:0051146 129 0.012
regulation of cell cycle process GO:0010564 20 0.012
negative regulation of cell communication GO:0010648 96 0.012
macromolecular complex disassembly GO:0032984 1 0.012
neural crest cell development GO:0014032 62 0.012
secondary metabolic process GO:0019748 3 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
negative regulation of gliogenesis GO:0014014 1 0.012
cell projection assembly GO:0030031 64 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
behavior GO:0007610 74 0.011
Zebrafish Mouse
central nervous system neuron differentiation GO:0021953 74 0.011
positive regulation of cell communication GO:0010647 56 0.011
Mouse
somatic muscle development GO:0007525 4 0.011
regulation of phosphorus metabolic process GO:0051174 43 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
regulation of rna metabolic process GO:0051252 224 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
response to external biotic stimulus GO:0043207 97 0.011
lateral inhibition GO:0046331 1 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
embryonic skeletal system development GO:0048706 97 0.011
negative regulation of multi organism process GO:0043901 3 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
regulation of mitotic cell cycle GO:0007346 25 0.011
organelle organization GO:0006996 227 0.011
lens fiber cell development GO:0070307 3 0.011
ensheathment of neurons GO:0007272 18 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
Mouse
negative regulation of metabolic process GO:0009892 86 0.011
myelination GO:0042552 18 0.011
negative regulation of cell migration GO:0030336 17 0.011
positive regulation of cell activation GO:0050867 1 0.011
peptidyl serine modification GO:0018209 2 0.010
anterior posterior pattern specification GO:0009952 152 0.010
activation of mapk activity GO:0000187 3 0.010
melanin metabolic process GO:0006582 2 0.010
regulation of growth GO:0040008 42 0.010
autophagy GO:0006914 4 0.010
muscle cell migration GO:0014812 4 0.010
reproduction GO:0000003 40 0.010
positive regulation of catalytic activity GO:0043085 25 0.010
cell proliferation GO:0008283 80 0.010
axon guidance GO:0007411 86 0.010
negative regulation of secretion GO:0051048 2 0.010
regulation of developmental growth GO:0048638 38 0.010
stem cell development GO:0048864 82 0.010
sexual reproduction GO:0019953 36 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
leukocyte homeostasis GO:0001776 2 0.010

slc1a3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.032
disease of anatomical entity DOID:7 0 0.032
Human
musculoskeletal system disease DOID:17 0 0.014
nervous system disease DOID:863 0 0.012
Human
bone development disease DOID:0080006 0 0.012
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012