Danio rerio

17 known processes

prkcsh

protein kinase C substrate 80K-H

(Aliases: zgc:55653,MGC55653)

prkcsh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.386
cellular response to topologically incorrect protein GO:0035967 2 0.248
embryo development ending in birth or egg hatching GO:0009792 271 0.168
cellular response to unfolded protein GO:0034620 2 0.113
multicellular organism growth GO:0035264 4 0.112
response to topologically incorrect protein GO:0035966 2 0.109
aging GO:0007568 2 0.104
response to stress GO:0006950 263 0.098
signal transduction GO:0007165 455 0.093
regulation of multicellular organism growth GO:0040014 4 0.085
endoplasmic reticulum unfolded protein response GO:0030968 2 0.072
cytokinesis GO:0000910 3 0.071
purine nucleoside monophosphate catabolic process GO:0009128 4 0.068
cellular macromolecule metabolic process GO:0044260 391 0.068
ribonucleoside monophosphate catabolic process GO:0009158 4 0.063
small molecule metabolic process GO:0044281 77 0.062
growth GO:0040007 174 0.061
generation of neurons GO:0048699 385 0.061
maintenance of location GO:0051235 4 0.060
cellular response to external stimulus GO:0071496 2 0.060
er nucleus signaling pathway GO:0006984 2 0.058
embryonic organ development GO:0048568 381 0.056
macromolecule biosynthetic process GO:0009059 227 0.055
nitrogen compound metabolic process GO:0006807 319 0.054
cellular protein modification process GO:0006464 100 0.053
response to unfolded protein GO:0006986 2 0.052
organelle organization GO:0006996 227 0.051
heterocycle metabolic process GO:0046483 290 0.050
transport GO:0006810 220 0.049
locomotion GO:0040011 313 0.048
establishment of protein localization to organelle GO:0072594 4 0.048
carboxylic acid metabolic process GO:0019752 22 0.048
cellular response to nutrient levels GO:0031669 2 0.047
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.047
programmed cell death GO:0012501 119 0.047
cellular nitrogen compound metabolic process GO:0034641 290 0.045
developmental growth GO:0048589 166 0.044
cell death GO:0008219 121 0.043
single organism metabolic process GO:0044710 217 0.042
nucleobase containing compound metabolic process GO:0006139 274 0.042
nucleoside monophosphate catabolic process GO:0009125 4 0.042
aromatic compound biosynthetic process GO:0019438 217 0.042
regulation of cell shape GO:0008360 1 0.041
heterocycle biosynthetic process GO:0018130 215 0.041
regulation of cell death GO:0010941 103 0.040
regulation of biological quality GO:0065008 263 0.040
organic cyclic compound metabolic process GO:1901360 301 0.039
regulation of protein transport GO:0051223 3 0.039
oxoacid metabolic process GO:0043436 31 0.038
response to chemical GO:0042221 320 0.038
response to organic substance GO:0010033 153 0.038
positive regulation of transport GO:0051050 2 0.037
positive regulation of protein complex assembly GO:0031334 2 0.037
neuron development GO:0048666 262 0.037
organic acid metabolic process GO:0006082 31 0.036
regulation of protein complex assembly GO:0043254 3 0.036
cellular response to extracellular stimulus GO:0031668 2 0.036
organic substance biosynthetic process GO:1901576 289 0.036
cytoskeleton dependent cytokinesis GO:0061640 3 0.035
carbohydrate derivative metabolic process GO:1901135 61 0.035
nucleic acid templated transcription GO:0097659 181 0.035
sensory organ development GO:0007423 393 0.035
cellular biosynthetic process GO:0044249 286 0.034
organonitrogen compound metabolic process GO:1901564 74 0.034
positive regulation of cellular component biogenesis GO:0044089 3 0.034
regulation of protein ubiquitination GO:0031396 3 0.033
establishment of localization GO:0051234 244 0.033
lipid storage GO:0019915 1 0.033
cellular component biogenesis GO:0044085 178 0.033
homeostatic process GO:0042592 142 0.033
atp catabolic process GO:0006200 4 0.032
hepaticobiliary system development GO:0061008 98 0.032
biosynthetic process GO:0009058 294 0.032
stem cell proliferation GO:0072089 4 0.031
cellular component assembly GO:0022607 170 0.031
protein modification process GO:0036211 100 0.030
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.030
protein import GO:0017038 3 0.030
cellular response to chemical stimulus GO:0070887 157 0.030
cellular response to starvation GO:0009267 1 0.030
protein metabolic process GO:0019538 183 0.030
regulation of apoptotic process GO:0042981 98 0.029
cell morphogenesis GO:0000902 289 0.029
regionalization GO:0003002 274 0.029
regulation of nucleoside metabolic process GO:0009118 2 0.028
death GO:0016265 121 0.028
amine metabolic process GO:0009308 2 0.027
regulation of protein binding GO:0043393 3 0.027
regulation of binding GO:0051098 3 0.027
tube morphogenesis GO:0035239 349 0.027
microtubule organizing center organization GO:0031023 1 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
positive regulation of catabolic process GO:0009896 4 0.027
cellular amino acid metabolic process GO:0006520 7 0.027
cellular amine metabolic process GO:0044106 2 0.026
positive regulation of biological process GO:0048518 253 0.026
organelle fusion GO:0048284 3 0.026
single organism localization GO:1902578 225 0.026
guanosine containing compound metabolic process GO:1901068 4 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
gland development GO:0048732 143 0.025
peptidyl serine phosphorylation GO:0018105 1 0.025
regulation of protein localization to nucleus GO:1900180 2 0.025
mitochondrion organization GO:0007005 4 0.025
endosomal transport GO:0016197 2 0.025
carbohydrate derivative biosynthetic process GO:1901137 43 0.025
single organism nuclear import GO:1902593 3 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
cellular component disassembly GO:0022411 1 0.024
regulation of programmed cell death GO:0043067 101 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
regulation of cell projection assembly GO:0060491 4 0.024
apoptotic process GO:0006915 116 0.024
nuclear import GO:0051170 3 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
protein polymerization GO:0051258 4 0.023
morphogenesis of an epithelium GO:0002009 333 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.022
neuroblast proliferation GO:0007405 2 0.022
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
gtp metabolic process GO:0046039 4 0.022
cellular component morphogenesis GO:0032989 336 0.022
protein dephosphorylation GO:0006470 3 0.022
nuclear transport GO:0051169 4 0.022
digestive tract development GO:0048565 265 0.022
rna biosynthetic process GO:0032774 181 0.022
protein import into nucleus GO:0006606 3 0.021
protein localization to nucleus GO:0034504 3 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.021
protein targeting to nucleus GO:0044744 3 0.021
positive regulation of apoptotic signaling pathway GO:2001235 1 0.021
embryonic organ morphogenesis GO:0048562 274 0.021
regulation of signal transduction GO:0009966 225 0.021
cell motility GO:0048870 244 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
regulation of rna metabolic process GO:0051252 224 0.021
gtp catabolic process GO:0006184 2 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.021
response to drug GO:0042493 3 0.021
macroautophagy GO:0016236 1 0.021
cellular protein metabolic process GO:0044267 129 0.021
regulation of stem cell proliferation GO:0072091 2 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
protein n linked glycosylation GO:0006487 1 0.021
dorsal ventral pattern formation GO:0009953 125 0.021
response to abiotic stimulus GO:0009628 122 0.020
specification of symmetry GO:0009799 204 0.020
regulation of filopodium assembly GO:0051489 2 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.020
regulation of response to stimulus GO:0048583 269 0.020
spindle assembly GO:0051225 2 0.020
heart development GO:0007507 313 0.020
regulation of cell communication GO:0010646 232 0.020
cell projection organization GO:0030030 284 0.020
reproduction GO:0000003 40 0.019
macromolecule modification GO:0043412 111 0.019
autophagy GO:0006914 4 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
regulation of wound healing GO:0061041 2 0.019
epithelial tube morphogenesis GO:0060562 148 0.019
positive regulation of cell cycle GO:0045787 3 0.019
cellular ketone metabolic process GO:0042180 11 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
digestive system development GO:0055123 289 0.018
nucleotide metabolic process GO:0009117 28 0.018
membrane fusion GO:0061025 2 0.018
ear development GO:0043583 127 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
regulation of developmental process GO:0050793 247 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
glycoprotein metabolic process GO:0009100 23 0.018
negative regulation of biological process GO:0048519 304 0.018
neurotransmitter transport GO:0006836 2 0.018
cellular component movement GO:0006928 335 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.018
single organism organelle organization GO:1902589 199 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
regulation of metabolic process GO:0019222 359 0.018
regulation of protein targeting GO:1903533 2 0.018
nucleocytoplasmic transport GO:0006913 4 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
centrosome duplication GO:0051298 1 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
sensory organ morphogenesis GO:0090596 200 0.017
rna metabolic process GO:0016070 219 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
peptide metabolic process GO:0006518 1 0.017
regulation of signaling GO:0023051 235 0.017
phosphorus metabolic process GO:0006793 109 0.017
protein localization to plasma membrane GO:0072659 1 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
determination of left right symmetry GO:0007368 179 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
protein secretion GO:0009306 1 0.016
single organism biosynthetic process GO:0044711 71 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
phagocytosis GO:0006909 3 0.016
regulation of cytokine production GO:0001817 3 0.016
regulation of cell substrate adhesion GO:0010810 1 0.016
determination of bilateral symmetry GO:0009855 204 0.016
secondary metabolic process GO:0019748 3 0.016
regulation of cellular component organization GO:0051128 86 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.016
chordate embryonic development GO:0043009 271 0.016
regulation of protein catabolic process GO:0042176 1 0.016
single organism transport GO:0044765 206 0.016
regulation of gtpase activity GO:0043087 2 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.016
organic substance transport GO:0071702 58 0.016
positive regulation of cellular process GO:0048522 201 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
protein complex localization GO:0031503 1 0.016
developmental programmed cell death GO:0010623 4 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
immune system process GO:0002376 241 0.016
negative regulation of catabolic process GO:0009895 3 0.016
cellular amide metabolic process GO:0043603 4 0.015
liver development GO:0001889 96 0.015
stem cell division GO:0017145 1 0.015
cellular response to stress GO:0033554 62 0.015
nucleic acid metabolic process GO:0090304 244 0.015
transcription dna templated GO:0006351 181 0.015
regulation of cell activation GO:0050865 1 0.015
centrosome cycle GO:0007098 1 0.015
compound eye development GO:0048749 2 0.015
cell projection morphogenesis GO:0048858 244 0.015
positive regulation of secretion GO:0051047 1 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
nuclear envelope organization GO:0006998 2 0.015
negative regulation of protein transport GO:0051224 3 0.015
negative regulation of programmed cell death GO:0043069 58 0.015
response to external stimulus GO:0009605 264 0.015
centrosome organization GO:0051297 1 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
regulation of cytoplasmic transport GO:1903649 4 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
adult behavior GO:0030534 2 0.014
meiotic nuclear division GO:0007126 4 0.014
negative regulation of apoptotic process GO:0043066 55 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
regulation of transcription dna templated GO:0006355 213 0.014
spindle assembly involved in mitosis GO:0090307 1 0.014
gene expression GO:0010467 252 0.014
meiotic chromosome segregation GO:0045132 3 0.014
regulation of catalytic activity GO:0050790 55 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
localization of cell GO:0051674 244 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
neuromuscular synaptic transmission GO:0007274 2 0.014
mitotic cell cycle GO:0000278 64 0.014
mitotic cytokinesis GO:0000281 3 0.014
exocytosis GO:0006887 1 0.014
activation of mapk activity GO:0000187 3 0.014
cell substrate adhesion GO:0031589 4 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
response to hydrogen peroxide GO:0042542 3 0.014
heart morphogenesis GO:0003007 156 0.014
cell part morphogenesis GO:0032990 246 0.014
macromolecule localization GO:0033036 54 0.013
regulation of biosynthetic process GO:0009889 250 0.013
regulation of localization GO:0032879 104 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
synaptic vesicle transport GO:0048489 1 0.013
chemosensory behavior GO:0007635 1 0.013
cellular response to organic substance GO:0071310 105 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
inner ear development GO:0048839 126 0.013
leukocyte proliferation GO:0070661 1 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.013
macromolecular complex disassembly GO:0032984 1 0.013
cell migration GO:0016477 237 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
regulation of receptor activity GO:0010469 2 0.013
cell migration involved in gastrulation GO:0042074 79 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
peptide transport GO:0015833 1 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
transmembrane transport GO:0055085 120 0.013
nucleobase containing small molecule metabolic process GO:0055086 32 0.013
regulation of molecular function GO:0065009 70 0.012
single fertilization GO:0007338 3 0.012
regulation of gene expression GO:0010468 265 0.012
single organism membrane fusion GO:0044801 2 0.012
peptidyl serine modification GO:0018209 2 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
synaptic vesicle localization GO:0097479 1 0.012
synaptic vesicle recycling GO:0036465 1 0.012
apoptotic process involved in development GO:1902742 2 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
stem cell maintenance GO:0019827 4 0.012
g2 m transition of mitotic cell cycle GO:0000086 4 0.012
female sex differentiation GO:0046660 4 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
renal tubule morphogenesis GO:0061333 1 0.012
response to alkaloid GO:0043279 2 0.012
ameboidal type cell migration GO:0001667 143 0.012
neuron projection morphogenesis GO:0048812 161 0.012
nephron epithelium morphogenesis GO:0072088 1 0.012
cell substrate junction assembly GO:0007044 2 0.012
response to antibiotic GO:0046677 1 0.012
golgi vesicle transport GO:0048193 3 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
neutrophil mediated immunity GO:0002446 1 0.012
brain development GO:0007420 293 0.012
system process GO:0003008 185 0.012
regulation of reproductive process GO:2000241 4 0.012
regulation of circadian rhythm GO:0042752 4 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
meiotic cell cycle process GO:1903046 3 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
glycosylation GO:0070085 11 0.012
neuron projection development GO:0031175 180 0.011
purine ribonucleotide metabolic process GO:0009150 27 0.011
lamellipodium assembly GO:0030032 1 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
regulation of jak stat cascade GO:0046425 3 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
skeletal system development GO:0001501 181 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
lamellipodium organization GO:0097581 1 0.011
cognition GO:0050890 1 0.011
axon ensheathment in central nervous system GO:0032291 2 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
axon development GO:0061564 166 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
actin filament polymerization GO:0030041 2 0.011
hormone secretion GO:0046879 2 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
multi organism process GO:0051704 134 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
locomotor rhythm GO:0045475 3 0.011
lateral inhibition GO:0046331 1 0.011
wound healing GO:0042060 90 0.011
organelle assembly GO:0070925 110 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
chemical homeostasis GO:0048878 49 0.011
digestive tract morphogenesis GO:0048546 231 0.011
carbohydrate homeostasis GO:0033500 1 0.011
taxis GO:0042330 109 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
cellular protein catabolic process GO:0044257 4 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
positive regulation of notch signaling pathway GO:0045747 3 0.011
regulation of exocytosis GO:0017157 1 0.011
embryonic heart tube development GO:0035050 133 0.010
glycoprotein biosynthetic process GO:0009101 21 0.010
positive regulation of cell activation GO:0050867 1 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
neuron differentiation GO:0030182 353 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
central nervous system development GO:0007417 387 0.010
actin filament based movement GO:0030048 1 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
regulation of blood vessel size GO:0050880 2 0.010
cellular respiration GO:0045333 3 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
gastrulation GO:0007369 208 0.010
nephron morphogenesis GO:0072028 2 0.010
positive regulation of protein polymerization GO:0032273 2 0.010

prkcsh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.075
nervous system disease DOID:863 0 0.047
disease of metabolism DOID:0014667 0 0.024
inherited metabolic disorder DOID:655 0 0.024
cardiovascular system disease DOID:1287 0 0.012
musculoskeletal system disease DOID:17 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
myopathy DOID:423 0 0.010
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010