Danio rerio

0 known processes

dffa

DNA fragmentation factor, alpha polypeptide

(Aliases: zgc:92229)

dffa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.082
larval development GO:0002164 2 0.071
cellular biosynthetic process GO:0044249 286 0.069
regulation of macromolecule metabolic process GO:0060255 317 0.063
nucleic acid metabolic process GO:0090304 244 0.054
cellular macromolecule metabolic process GO:0044260 391 0.053
heterocycle biosynthetic process GO:0018130 215 0.047
nitrogen compound metabolic process GO:0006807 319 0.047
cellular nitrogen compound metabolic process GO:0034641 290 0.047
cellular nitrogen compound biosynthetic process GO:0044271 218 0.047
maintenance of location GO:0051235 4 0.046
aromatic compound biosynthetic process GO:0019438 217 0.045
regulation of macromolecule biosynthetic process GO:0010556 225 0.045
multicellular organism growth GO:0035264 4 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.044
positive regulation of transport GO:0051050 2 0.043
regulation of multicellular organism growth GO:0040014 4 0.043
nucleobase containing compound biosynthetic process GO:0034654 205 0.042
organic cyclic compound metabolic process GO:1901360 301 0.041
biosynthetic process GO:0009058 294 0.040
organic cyclic compound biosynthetic process GO:1901362 223 0.040
rna metabolic process GO:0016070 219 0.040
cellular macromolecule biosynthetic process GO:0034645 224 0.040
organic substance biosynthetic process GO:1901576 289 0.039
negative regulation of biological process GO:0048519 304 0.039
proteasomal protein catabolic process GO:0010498 2 0.038
heterocycle metabolic process GO:0046483 290 0.038
lipid storage GO:0019915 1 0.037
macromolecule biosynthetic process GO:0009059 227 0.037
nucleobase containing compound metabolic process GO:0006139 274 0.035
cellular protein catabolic process GO:0044257 4 0.035
transcription dna templated GO:0006351 181 0.035
nucleic acid templated transcription GO:0097659 181 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.034
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.032
regulation of protein ubiquitination GO:0031396 3 0.032
regulation of nucleic acid templated transcription GO:1903506 213 0.031
ubiquitin dependent protein catabolic process GO:0006511 3 0.031
regulation of primary metabolic process GO:0080090 311 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
gene expression GO:0010467 252 0.031
rna biosynthetic process GO:0032774 181 0.031
regulation of rna metabolic process GO:0051252 224 0.031
positive regulation of biological process GO:0048518 253 0.030
negative regulation of cellular process GO:0048523 283 0.030
synaptic growth at neuromuscular junction GO:0051124 2 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
regulation of metabolic process GO:0019222 359 0.030
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.029
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.029
nucleoside monophosphate catabolic process GO:0009125 4 0.029
negative regulation of protein phosphorylation GO:0001933 4 0.029
regulation of cellular metabolic process GO:0031323 320 0.028
positive regulation of catabolic process GO:0009896 4 0.028
response to chemical GO:0042221 320 0.028
positive regulation of cell cycle GO:0045787 3 0.027
regulation of transcription dna templated GO:0006355 213 0.027
response to drug GO:0042493 3 0.027
regulation of binding GO:0051098 3 0.027
regulation of gene expression GO:0010468 265 0.027
positive regulation of cellular catabolic process GO:0031331 3 0.026
atp catabolic process GO:0006200 4 0.026
eye development GO:0001654 277 0.026
amine metabolic process GO:0009308 2 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
organic acid metabolic process GO:0006082 31 0.026
embryonic organ development GO:0048568 381 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
regulation of biosynthetic process GO:0009889 250 0.025
sensory organ development GO:0007423 393 0.025
purine nucleoside monophosphate catabolic process GO:0009128 4 0.025
single organism metabolic process GO:0044710 217 0.025
regulation of synapse organization GO:0050807 3 0.025
central nervous system development GO:0007417 387 0.025
single organism membrane fusion GO:0044801 2 0.025
head development GO:0060322 303 0.024
stem cell maintenance GO:0019827 4 0.024
exocytosis GO:0006887 1 0.024
meiotic nuclear division GO:0007126 4 0.024
regulation of metal ion transport GO:0010959 4 0.024
modification dependent protein catabolic process GO:0019941 3 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
regulation of protein transport GO:0051223 3 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
cellular amine metabolic process GO:0044106 2 0.023
nuclear transport GO:0051169 4 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
phagocytosis GO:0006909 3 0.022
mitochondrion organization GO:0007005 4 0.022
cellular ketone metabolic process GO:0042180 11 0.022
response to stress GO:0006950 263 0.022
nuclear migration GO:0007097 3 0.022
oxoacid metabolic process GO:0043436 31 0.021
positive regulation of secretion by cell GO:1903532 1 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.021
lateral inhibition GO:0046331 1 0.021
cytokinesis GO:0000910 3 0.021
regulation of cell activation GO:0050865 1 0.021
hemopoiesis GO:0030097 183 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
small molecule metabolic process GO:0044281 77 0.021
endosomal transport GO:0016197 2 0.020
regulation of cytokine production GO:0001817 3 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
stem cell proliferation GO:0072089 4 0.020
regulation of signaling GO:0023051 235 0.020
regulation of protein catabolic process GO:0042176 1 0.020
adult behavior GO:0030534 2 0.020
regulation of biological quality GO:0065008 263 0.020
meiotic cell cycle process GO:1903046 3 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
heart development GO:0007507 313 0.020
cellular amino acid metabolic process GO:0006520 7 0.019
membrane fusion GO:0061025 2 0.019
regulation of synapse assembly GO:0051963 3 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
system process GO:0003008 185 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
protein metabolic process GO:0019538 183 0.019
signal transduction GO:0007165 455 0.019
compound eye development GO:0048749 2 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
regulation of meiotic cell cycle GO:0051445 1 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
leukocyte proliferation GO:0070661 1 0.018
embryo development ending in birth or egg hatching GO:0009792 271 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
positive regulation of map kinase activity GO:0043406 3 0.018
brain development GO:0007420 293 0.018
positive regulation of cellular process GO:0048522 201 0.018
growth GO:0040007 174 0.018
regulation of cell shape GO:0008360 1 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
gtp catabolic process GO:0006184 2 0.018
gtp metabolic process GO:0046039 4 0.018
organelle organization GO:0006996 227 0.018
immune system process GO:0002376 241 0.018
regulation of dendrite development GO:0050773 3 0.018
protein localization to nucleus GO:0034504 3 0.018
regulation of synaptic plasticity GO:0048167 1 0.017
protein import into nucleus GO:0006606 3 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
nuclear import GO:0051170 3 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.017
chordate embryonic development GO:0043009 271 0.017
female gonad development GO:0008585 4 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
regulation of circadian rhythm GO:0042752 4 0.017
tissue remodeling GO:0048771 4 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
cellular component morphogenesis GO:0032989 336 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of erk1 and erk2 cascade GO:0070372 4 0.017
regulation of developmental process GO:0050793 247 0.017
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.017
fertilization GO:0009566 3 0.017
protein targeting to nucleus GO:0044744 3 0.016
golgi vesicle transport GO:0048193 3 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
female sex differentiation GO:0046660 4 0.016
response to topologically incorrect protein GO:0035966 2 0.016
single fertilization GO:0007338 3 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
regulation of response to stimulus GO:0048583 269 0.016
neurotransmitter transport GO:0006836 2 0.016
protein import GO:0017038 3 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
positive regulation of cell activation GO:0050867 1 0.016
hormone secretion GO:0046879 2 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
regulation of cell communication GO:0010646 232 0.016
primary neural tube formation GO:0014020 1 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
mitotic dna integrity checkpoint GO:0044774 4 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
regulation of blood pressure GO:0008217 1 0.016
cellular protein metabolic process GO:0044267 129 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
protein heterooligomerization GO:0051291 1 0.015
peptide metabolic process GO:0006518 1 0.015
cell substrate adhesion GO:0031589 4 0.015
regulation of receptor activity GO:0010469 2 0.015
regulation of protein complex assembly GO:0043254 3 0.015
autophagy GO:0006914 4 0.015
stem cell division GO:0017145 1 0.015
regulation of dna replication GO:0006275 3 0.015
cell morphogenesis GO:0000902 289 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
protein localization to plasma membrane GO:0072659 1 0.015
meiosis i GO:0007127 1 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
organelle fusion GO:0048284 3 0.015
regulation of protein binding GO:0043393 3 0.015
positive regulation of secretion GO:0051047 1 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
regulation of chromosome segregation GO:0051983 1 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
cognition GO:0050890 1 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
regulation of reproductive process GO:2000241 4 0.014
regulation of organ growth GO:0046620 3 0.014
mononuclear cell proliferation GO:0032943 1 0.014
developmental growth GO:0048589 166 0.014
cellular response to oxygen levels GO:0071453 1 0.014
peptidyl serine modification GO:0018209 2 0.014
immune system development GO:0002520 191 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
somatic muscle development GO:0007525 4 0.014
regulation of hormone secretion GO:0046883 2 0.014
tube closure GO:0060606 1 0.014
cellular component movement GO:0006928 335 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
peptide transport GO:0015833 1 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
phosphorus metabolic process GO:0006793 109 0.014
meiotic chromosome segregation GO:0045132 3 0.014
death GO:0016265 121 0.014
epithelial cell differentiation GO:0030855 116 0.014
positive regulation of immune effector process GO:0002699 3 0.014
regulation of transporter activity GO:0032409 2 0.014
protein polymerization GO:0051258 4 0.014
long chain fatty acid metabolic process GO:0001676 1 0.014
regulation of response to cytokine stimulus GO:0060759 3 0.014
negative regulation of kinase activity GO:0033673 4 0.014
eye morphogenesis GO:0048592 144 0.013
muscle cell migration GO:0014812 4 0.013
developmental programmed cell death GO:0010623 4 0.013
generation of neurons GO:0048699 385 0.013
endocrine process GO:0050886 2 0.013
secondary metabolic process GO:0019748 3 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
single organism localization GO:1902578 225 0.013
negative regulation of nuclear division GO:0051784 3 0.013
negative regulation of cytokine production GO:0001818 1 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
response to vitamin GO:0033273 3 0.013
regulation of blood vessel size GO:0050880 2 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
cellular response to hypoxia GO:0071456 1 0.013
protein secretion GO:0009306 1 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.013
lysosomal transport GO:0007041 2 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
regulation of cell death GO:0010941 103 0.013
camera type eye development GO:0043010 222 0.013
protein modification process GO:0036211 100 0.013
digestive system development GO:0055123 289 0.013
negative regulation of catabolic process GO:0009895 3 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
regulation of gtpase activity GO:0043087 2 0.013
multicellular organismal response to stress GO:0033555 2 0.013
cellular modified amino acid metabolic process GO:0006575 3 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
positive regulation of cytokine production GO:0001819 2 0.013
neuron differentiation GO:0030182 353 0.013
sleep GO:0030431 1 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
multicellular organismal metabolic process GO:0044236 2 0.012
negative regulation of protein transport GO:0051224 3 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
rna localization GO:0006403 4 0.012
neurotransmitter secretion GO:0007269 2 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
lymphocyte proliferation GO:0046651 1 0.012
cellular amide metabolic process GO:0043603 4 0.012
adherens junction organization GO:0034332 4 0.012
response to unfolded protein GO:0006986 2 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
regulation of signal transduction GO:0009966 225 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
regulation of protein targeting GO:1903533 2 0.012
homeostatic process GO:0042592 142 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
single organism transport GO:0044765 206 0.012
regulation of jak stat cascade GO:0046425 3 0.012
protein k48 linked ubiquitination GO:0070936 1 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
germ line stem cell maintenance GO:0030718 2 0.012
response to organic substance GO:0010033 153 0.012
cellular protein modification process GO:0006464 100 0.012
regionalization GO:0003002 274 0.012
protein dephosphorylation GO:0006470 3 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
cell motility GO:0048870 244 0.012
establishment of localization GO:0051234 244 0.012
cell aging GO:0007569 2 0.012
macromolecule modification GO:0043412 111 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
sensory organ morphogenesis GO:0090596 200 0.012
sensory perception of pain GO:0019233 1 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
post embryonic organ development GO:0048569 4 0.012
cellular response to nutrient levels GO:0031669 2 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
response to external stimulus GO:0009605 264 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
response to corticosteroid GO:0031960 1 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
tube morphogenesis GO:0035239 349 0.012
regulation of wound healing GO:0061041 2 0.012
positive regulation of metabolic process GO:0009893 108 0.012
response to uv GO:0009411 3 0.012
response to nutrient GO:0007584 3 0.011
transport GO:0006810 220 0.011
regulation of calcium ion transport GO:0051924 2 0.011
dna templated transcription elongation GO:0006354 3 0.011
blood vessel development GO:0001568 246 0.011
intracellular signal transduction GO:0035556 85 0.011
positive regulation of cell division GO:0051781 2 0.011
response to monosaccharide GO:0034284 3 0.011
cell migration GO:0016477 237 0.011
response to hexose GO:0009746 3 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
cellular lipid catabolic process GO:0044242 3 0.011
cellular component disassembly GO:0022411 1 0.011
regulation of tube size GO:0035150 2 0.011
response to glucocorticoid GO:0051384 1 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
cortical actin cytoskeleton organization GO:0030866 1 0.011
b cell activation GO:0042113 2 0.011
heart morphogenesis GO:0003007 156 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
localization of cell GO:0051674 244 0.011
wound healing GO:0042060 90 0.011
response to other organism GO:0051707 97 0.011
negative regulation of metabolic process GO:0009892 86 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
hormone transport GO:0009914 2 0.011
chemosensory behavior GO:0007635 1 0.011
cellular response to external stimulus GO:0071496 2 0.011
regulation of epithelial to mesenchymal transition GO:0010717 3 0.011
nuclear export GO:0051168 1 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
protein stabilization GO:0050821 2 0.011
somite development GO:0061053 96 0.011
cation transport GO:0006812 81 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
membrane lipid biosynthetic process GO:0046467 2 0.010
interspecies interaction between organisms GO:0044419 4 0.010
calcium ion dependent exocytosis GO:0017156 1 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
double strand break repair GO:0006302 3 0.010
response to abiotic stimulus GO:0009628 122 0.010
protein acylation GO:0043543 3 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
recombinational repair GO:0000725 1 0.010
negative regulation of apoptotic process GO:0043066 55 0.010
negative regulation of ras protein signal transduction GO:0046580 1 0.010
embryonic limb morphogenesis GO:0030326 2 0.010
negative regulation of cell communication GO:0010648 96 0.010
ameboidal type cell migration GO:0001667 143 0.010
b cell differentiation GO:0030183 1 0.010
neuroblast proliferation GO:0007405 2 0.010
regulation of mrna processing GO:0050684 3 0.010
endoplasmic reticulum unfolded protein response GO:0030968 2 0.010
locomotion GO:0040011 313 0.010
protein homooligomerization GO:0051260 3 0.010
protein complex disassembly GO:0043241 1 0.010
fatty acid biosynthetic process GO:0006633 4 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
cell part morphogenesis GO:0032990 246 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
cellular component assembly GO:0022607 170 0.010
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.010

dffa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.034
inherited metabolic disorder DOID:655 0 0.034
disease of anatomical entity DOID:7 0 0.027
musculoskeletal system disease DOID:17 0 0.017
muscular disease DOID:0080000 0 0.014
muscle tissue disease DOID:66 0 0.014
nervous system disease DOID:863 0 0.014
myopathy DOID:423 0 0.012
immune system disease DOID:2914 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011