Danio rerio

0 known processes

kdelr2

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

(Aliases: cb768,wu:fi21a12,wu:fa11g06,zgc:63777)

kdelr2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
golgi vesicle transport GO:0048193 3 0.530
larval development GO:0002164 2 0.489
er to golgi vesicle mediated transport GO:0006888 1 0.391
cellular response to estrogen stimulus GO:0071391 24 0.300
localization within membrane GO:0051668 1 0.286
maintenance of location GO:0051235 4 0.181
regulation of response to stimulus GO:0048583 269 0.161
cellular component morphogenesis GO:0032989 336 0.161
lipid storage GO:0019915 1 0.151
aging GO:0007568 2 0.147
cellular response to steroid hormone stimulus GO:0071383 31 0.129
locomotion GO:0040011 313 0.123
establishment of localization in cell GO:0051649 77 0.109
positive regulation of transport GO:0051050 2 0.103
cellular response to topologically incorrect protein GO:0035967 2 0.098
organic substance biosynthetic process GO:1901576 289 0.095
transport GO:0006810 220 0.092
cellular macromolecule metabolic process GO:0044260 391 0.090
single organism transport GO:0044765 206 0.085
single organism localization GO:1902578 225 0.085
response to chemical GO:0042221 320 0.080
golgi organization GO:0007030 1 0.079
positive regulation of biological process GO:0048518 253 0.078
endomembrane system organization GO:0010256 13 0.078
cellular response to chemical stimulus GO:0070887 157 0.077
ossification GO:0001503 23 0.076
response to organic substance GO:0010033 153 0.073
behavior GO:0007610 74 0.070
protein metabolic process GO:0019538 183 0.069
organelle organization GO:0006996 227 0.068
cellular protein metabolic process GO:0044267 129 0.067
response to hormone GO:0009725 48 0.066
programmed cell death GO:0012501 119 0.065
response to topologically incorrect protein GO:0035966 2 0.063
cellular nitrogen compound metabolic process GO:0034641 290 0.062
cellular macromolecule biosynthetic process GO:0034645 224 0.062
embryo development ending in birth or egg hatching GO:0009792 271 0.056
cell morphogenesis GO:0000902 289 0.056
cell motility GO:0048870 244 0.055
cellular response to endogenous stimulus GO:0071495 68 0.053
cellular response to organic substance GO:0071310 105 0.053
regulation of macromolecule metabolic process GO:0060255 317 0.053
organelle localization GO:0051640 49 0.052
carbohydrate derivative metabolic process GO:1901135 61 0.051
nitrogen compound metabolic process GO:0006807 319 0.051
response to organic cyclic compound GO:0014070 51 0.050
cellular response to hormone stimulus GO:0032870 39 0.049
autophagy GO:0006914 4 0.048
regulation of cellular component organization GO:0051128 86 0.048
convergent extension GO:0060026 118 0.048
establishment of localization GO:0051234 244 0.047
hormone transport GO:0009914 2 0.047
growth GO:0040007 174 0.046
single organism cellular localization GO:1902580 46 0.046
regulation of signal transduction GO:0009966 225 0.045
regulation of multicellular organismal process GO:0051239 277 0.045
biosynthetic process GO:0009058 294 0.045
establishment of protein localization to organelle GO:0072594 4 0.044
cellular component biogenesis GO:0044085 178 0.044
positive regulation of cellular component biogenesis GO:0044089 3 0.044
phagocytosis GO:0006909 3 0.043
establishment of protein localization to plasma membrane GO:0090002 1 0.043
regulation of primary metabolic process GO:0080090 311 0.041
oxoacid metabolic process GO:0043436 31 0.041
negative regulation of cellular process GO:0048523 283 0.039
single organism membrane organization GO:0044802 20 0.038
regulation of establishment of protein localization GO:0070201 4 0.038
cell migration GO:0016477 237 0.038
single organism intracellular transport GO:1902582 25 0.037
positive regulation of cellular process GO:0048522 201 0.036
positive regulation of cellular metabolic process GO:0031325 94 0.036
regulation of metabolic process GO:0019222 359 0.035
regulation of protein binding GO:0043393 3 0.035
gtp metabolic process GO:0046039 4 0.035
establishment of vesicle localization GO:0051650 24 0.034
apoptotic process GO:0006915 116 0.034
regulation of hormone secretion GO:0046883 2 0.034
regulation of localization GO:0032879 104 0.034
regulation of nucleotide catabolic process GO:0030811 2 0.033
single organism organelle organization GO:1902589 199 0.033
cell part morphogenesis GO:0032990 246 0.033
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.033
protein localization GO:0008104 40 0.033
multicellular organismal macromolecule metabolic process GO:0044259 2 0.032
cellular component assembly GO:0022607 170 0.032
response to external biotic stimulus GO:0043207 97 0.032
single organism metabolic process GO:0044710 217 0.032
cellular localization GO:0051641 97 0.032
protein import GO:0017038 3 0.031
macromolecule biosynthetic process GO:0009059 227 0.030
guanosine containing compound catabolic process GO:1901069 2 0.030
cellular response to organic cyclic compound GO:0071407 38 0.030
nucleic acid templated transcription GO:0097659 181 0.029
regulation of cellular biosynthetic process GO:0031326 245 0.029
extrinsic apoptotic signaling pathway GO:0097191 3 0.029
sensory perception of chemical stimulus GO:0007606 3 0.029
gtp catabolic process GO:0006184 2 0.029
response to biotic stimulus GO:0009607 97 0.028
protein targeting to membrane GO:0006612 1 0.028
regulation of cellular metabolic process GO:0031323 320 0.028
macromolecule modification GO:0043412 111 0.027
response to estrogen GO:0043627 27 0.027
meiotic cell cycle process GO:1903046 3 0.027
regulation of cell communication GO:0010646 232 0.027
vesicle localization GO:0051648 27 0.027
rna localization GO:0006403 4 0.026
cellular protein modification process GO:0006464 100 0.026
positive regulation of catabolic process GO:0009896 4 0.026
regulation of protein metabolic process GO:0051246 56 0.026
amine metabolic process GO:0009308 2 0.026
regulation of biological quality GO:0065008 263 0.026
intracellular transport GO:0046907 32 0.026
positive regulation of developmental process GO:0051094 50 0.025
multicellular organism growth GO:0035264 4 0.025
regulation of binding GO:0051098 3 0.025
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.025
organic acid metabolic process GO:0006082 31 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
regulation of catalytic activity GO:0050790 55 0.024
regulation of signaling GO:0023051 235 0.024
death GO:0016265 121 0.024
central nervous system development GO:0007417 387 0.024
negative regulation of signal transduction GO:0009968 94 0.024
positive regulation of response to stimulus GO:0048584 80 0.023
cell death GO:0008219 121 0.023
vesicle organization GO:0016050 6 0.023
regulation of protein transport GO:0051223 3 0.023
peptide transport GO:0015833 1 0.023
cytokinesis GO:0000910 3 0.023
muscle structure development GO:0061061 196 0.022
regulation of metal ion transport GO:0010959 4 0.022
er nucleus signaling pathway GO:0006984 2 0.022
cell surface receptor signaling pathway GO:0007166 325 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
positive regulation of cellular biosynthetic process GO:0031328 68 0.021
cellular response to unfolded protein GO:0034620 2 0.021
regulation of transport GO:0051049 45 0.021
cell aging GO:0007569 2 0.021
regulation of stem cell differentiation GO:2000736 4 0.021
regulation of nucleoside metabolic process GO:0009118 2 0.020
protein modification process GO:0036211 100 0.020
positive regulation of secretion GO:0051047 1 0.020
regulation of organelle organization GO:0033043 29 0.020
positive regulation of apoptotic signaling pathway GO:2001235 1 0.020
intracellular mrna localization GO:0008298 1 0.019
membrane organization GO:0061024 21 0.019
response to endogenous stimulus GO:0009719 83 0.019
regulation of cell projection assembly GO:0060491 4 0.019
protein heterooligomerization GO:0051291 1 0.019
regulation of macromolecule biosynthetic process GO:0010556 225 0.019
gland development GO:0048732 143 0.019
transcription dna templated GO:0006351 181 0.019
regulation of protein complex assembly GO:0043254 3 0.019
positive regulation of metabolic process GO:0009893 108 0.019
positive regulation of secretion by cell GO:1903532 1 0.018
cell substrate junction assembly GO:0007044 2 0.018
response to lipid GO:0033993 60 0.018
cell projection assembly GO:0030031 64 0.018
nuclear import GO:0051170 3 0.018
ameboidal type cell migration GO:0001667 143 0.018
regulation of gtpase activity GO:0043087 2 0.018
apical junction assembly GO:0043297 1 0.018
organonitrogen compound metabolic process GO:1901564 74 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
protein secretion GO:0009306 1 0.017
head development GO:0060322 303 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.017
generation of neurons GO:0048699 385 0.017
lateral inhibition GO:0046331 1 0.017
regulation of cell shape GO:0008360 1 0.017
regulation of phosphorus metabolic process GO:0051174 43 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
heart development GO:0007507 313 0.017
embryonic organ development GO:0048568 381 0.017
regulation of rna metabolic process GO:0051252 224 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
cellular component movement GO:0006928 335 0.017
regulation of epithelial to mesenchymal transition GO:0010717 3 0.016
negative regulation of blood circulation GO:1903523 2 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
organic substance transport GO:0071702 58 0.016
response to unfolded protein GO:0006986 2 0.016
negative regulation of autophagy GO:0010507 1 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
response to drug GO:0042493 3 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
brain development GO:0007420 293 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
cellular ketone metabolic process GO:0042180 11 0.015
negative regulation of biological process GO:0048519 304 0.015
protein polymerization GO:0051258 4 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of cell death GO:0010941 103 0.015
regulation of cell activation GO:0050865 1 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
cytoplasmic transport GO:0016482 11 0.015
single organism reproductive process GO:0044702 40 0.015
cell projection morphogenesis GO:0048858 244 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
cellular component assembly involved in morphogenesis GO:0010927 107 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
transmembrane transport GO:0055085 120 0.015
hormone secretion GO:0046879 2 0.015
small molecule metabolic process GO:0044281 77 0.014
response to bacterium GO:0009617 58 0.014
multi organism process GO:0051704 134 0.014
developmental growth GO:0048589 166 0.014
iron ion transmembrane transport GO:0034755 3 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
positive regulation of signal transduction GO:0009967 56 0.014
regulation of cell morphogenesis GO:0022604 42 0.014
establishment of organelle localization GO:0051656 45 0.014
cellular pigmentation GO:0033059 30 0.014
negative regulation of catabolic process GO:0009895 3 0.013
regulation of locomotion GO:0040012 55 0.013
cell junction organization GO:0034330 11 0.013
macromolecule localization GO:0033036 54 0.013
establishment of protein localization to membrane GO:0090150 3 0.013
regulation of gene expression GO:0010468 265 0.013
cellular amine metabolic process GO:0044106 2 0.013
signal transduction GO:0007165 455 0.013
neurotransmitter transport GO:0006836 2 0.012
negative regulation of chemotaxis GO:0050922 4 0.012
heterocycle metabolic process GO:0046483 290 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
endothelial cell migration GO:0043542 19 0.012
negative regulation of myeloid cell differentiation GO:0045638 1 0.012
striated muscle cell differentiation GO:0051146 129 0.012
negative chemotaxis GO:0050919 1 0.012
collagen metabolic process GO:0032963 2 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
negative regulation of cell communication GO:0010648 96 0.011
protein targeting to nucleus GO:0044744 3 0.011
regulation of developmental process GO:0050793 247 0.011
positive regulation of protein metabolic process GO:0051247 23 0.011
cellular response to lipid GO:0071396 39 0.011
chemosensory behavior GO:0007635 1 0.011
regulation of biomineral tissue development GO:0070167 2 0.011
organelle assembly GO:0070925 110 0.011
cellular macromolecule localization GO:0070727 21 0.011
positive regulation of signaling GO:0023056 56 0.011
lipid biosynthetic process GO:0008610 22 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
gene expression GO:0010467 252 0.011
protein import into nucleus GO:0006606 3 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
rna metabolic process GO:0016070 219 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
viral process GO:0016032 1 0.011
stem cell maintenance GO:0019827 4 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
vesicle mediated transport GO:0016192 22 0.011
cellular biosynthetic process GO:0044249 286 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
negative regulation of signaling GO:0023057 96 0.011
positive regulation of muscle cell differentiation GO:0051149 1 0.011
reproductive process GO:0022414 40 0.011
negative regulation of locomotion GO:0040013 18 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
positive regulation of cell differentiation GO:0045597 30 0.010
response to steroid hormone GO:0048545 35 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
microtubule organizing center organization GO:0031023 1 0.010
modification dependent protein catabolic process GO:0019941 3 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
centrosome organization GO:0051297 1 0.010
localization of cell GO:0051674 244 0.010

kdelr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
muscular disease DOID:0080000 0 0.021
musculoskeletal system disease DOID:17 0 0.021
connective tissue disease DOID:65 0 0.020
osteochondrodysplasia DOID:2256 0 0.016
bone development disease DOID:0080006 0 0.016
bone disease DOID:0080001 0 0.016