Danio rerio

0 known processes

rbl2

retinoblastoma-like 2 (p130)

rbl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.050
positive regulation of transport GO:0051050 2 0.049
amino acid transport GO:0006865 2 0.039
maintenance of location GO:0051235 4 0.038
phagocytosis GO:0006909 3 0.037
lipid storage GO:0019915 1 0.036
neurotransmitter transport GO:0006836 2 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.035
multicellular organism growth GO:0035264 4 0.032
regulation of synapse organization GO:0050807 3 0.032
regulation of synapse assembly GO:0051963 3 0.030
cellular component movement GO:0006928 335 0.030
synaptic growth at neuromuscular junction GO:0051124 2 0.029
dicarboxylic acid transport GO:0006835 1 0.029
regulation of multicellular organism growth GO:0040014 4 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.027
sensory organ development GO:0007423 393 0.027
exocytosis GO:0006887 1 0.027
nucleoside monophosphate catabolic process GO:0009125 4 0.027
regulation of biological quality GO:0065008 263 0.026
endosomal transport GO:0016197 2 0.025
regulation of synaptic plasticity GO:0048167 1 0.025
neuromuscular process controlling balance GO:0050885 3 0.025
sensory perception of chemical stimulus GO:0007606 3 0.024
synaptic vesicle localization GO:0097479 1 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
cellular pigmentation GO:0033059 30 0.024
regulation of reproductive process GO:2000241 4 0.024
ribonucleoside monophosphate catabolic process GO:0009158 4 0.024
small molecule metabolic process GO:0044281 77 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.022
regulation of blood pressure GO:0008217 1 0.022
response to chemical GO:0042221 320 0.022
synaptic vesicle transport GO:0048489 1 0.022
neurotransmitter secretion GO:0007269 2 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
ubiquitin dependent protein catabolic process GO:0006511 3 0.022
adult behavior GO:0030534 2 0.022
establishment of localization GO:0051234 244 0.022
transport GO:0006810 220 0.022
single organism nuclear import GO:1902593 3 0.022
nuclear transport GO:0051169 4 0.021
membrane fusion GO:0061025 2 0.021
atp catabolic process GO:0006200 4 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.021
organic substance biosynthetic process GO:1901576 289 0.021
single organism membrane fusion GO:0044801 2 0.021
head development GO:0060322 303 0.021
regulation of epithelial cell proliferation GO:0050678 3 0.020
regulation of ion transmembrane transporter activity GO:0032412 2 0.020
establishment of synaptic vesicle localization GO:0097480 1 0.020
locomotion GO:0040011 313 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
response to drug GO:0042493 3 0.020
cell part morphogenesis GO:0032990 246 0.020
cytokinesis GO:0000910 3 0.020
neuron differentiation GO:0030182 353 0.020
regulation of circadian rhythm GO:0042752 4 0.020
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
cellular ketone metabolic process GO:0042180 11 0.020
mitochondrion organization GO:0007005 4 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
neuron development GO:0048666 262 0.019
cognition GO:0050890 1 0.019
protein targeting to nucleus GO:0044744 3 0.019
sensory organ morphogenesis GO:0090596 200 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
neuroblast proliferation GO:0007405 2 0.019
cellular protein catabolic process GO:0044257 4 0.019
regulation of tube size GO:0035150 2 0.019
aging GO:0007568 2 0.019
regulation of cytokine production GO:0001817 3 0.019
protein localization to nucleus GO:0034504 3 0.019
cell projection organization GO:0030030 284 0.019
organonitrogen compound metabolic process GO:1901564 74 0.018
regulation of mrna processing GO:0050684 3 0.018
regulation of binding GO:0051098 3 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
meiotic cell cycle process GO:1903046 3 0.018
amine metabolic process GO:0009308 2 0.018
macromolecular complex disassembly GO:0032984 1 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
sequestering of calcium ion GO:0051208 3 0.018
cellular amine metabolic process GO:0044106 2 0.018
eye development GO:0001654 277 0.018
response to carbohydrate GO:0009743 3 0.018
positive regulation of catabolic process GO:0009896 4 0.018
actin polymerization or depolymerization GO:0008154 2 0.018
regulation of metabolic process GO:0019222 359 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
modification dependent protein catabolic process GO:0019941 3 0.017
positive regulation of cell cycle GO:0045787 3 0.017
meiotic nuclear division GO:0007126 4 0.017
negative regulation of sequestering of calcium ion GO:0051283 4 0.017
gtp metabolic process GO:0046039 4 0.017
heart development GO:0007507 313 0.017
stem cell maintenance GO:0019827 4 0.017
mechanosensory behavior GO:0007638 2 0.017
spermatid differentiation GO:0048515 2 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
regulation of blood vessel size GO:0050880 2 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
negative regulation of synapse assembly GO:0051964 2 0.017
glucose homeostasis GO:0042593 1 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
central nervous system development GO:0007417 387 0.017
cell morphogenesis GO:0000902 289 0.017
single organism metabolic process GO:0044710 217 0.017
vasculature development GO:0001944 278 0.016
single organism localization GO:1902578 225 0.016
gtp catabolic process GO:0006184 2 0.016
protein complex disassembly GO:0043241 1 0.016
protein acylation GO:0043543 3 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
cellular nitrogen compound metabolic process GO:0034641 290 0.016
spermatid development GO:0007286 2 0.016
regulation of cell activation GO:0050865 1 0.016
positive regulation of secretion GO:0051047 1 0.016
regulation of gene expression GO:0010468 265 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
somatic muscle development GO:0007525 4 0.016
organelle organization GO:0006996 227 0.016
protein homooligomerization GO:0051260 3 0.016
cellular biosynthetic process GO:0044249 286 0.016
cellular component morphogenesis GO:0032989 336 0.016
regulation of neuronal synaptic plasticity GO:0048168 1 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.015
cellular macromolecule metabolic process GO:0044260 391 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
carbohydrate homeostasis GO:0033500 1 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
oxoacid metabolic process GO:0043436 31 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
autophagy GO:0006914 4 0.015
negative regulation of catabolic process GO:0009895 3 0.015
sequestering of metal ion GO:0051238 3 0.015
organic acid metabolic process GO:0006082 31 0.015
single organism transport GO:0044765 206 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
protein localization to plasma membrane GO:0072659 1 0.015
cellular component disassembly GO:0022411 1 0.015
protein import into nucleus GO:0006606 3 0.015
alcohol biosynthetic process GO:0046165 2 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
response to hydrogen peroxide GO:0042542 3 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
regulation of protein transport GO:0051223 3 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
protein acetylation GO:0006473 2 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
signal transduction GO:0007165 455 0.015
positive regulation of protein polymerization GO:0032273 2 0.015
protein import GO:0017038 3 0.015
protein polymerization GO:0051258 4 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
gene expression GO:0010467 252 0.015
regulation of protein complex assembly GO:0043254 3 0.015
nuclear import GO:0051170 3 0.015
embryonic organ development GO:0048568 381 0.015
female gonad development GO:0008585 4 0.015
regulation of metal ion transport GO:0010959 4 0.015
response to hexose GO:0009746 3 0.015
morphogenesis of an epithelium GO:0002009 333 0.014
positive regulation of notch signaling pathway GO:0045747 3 0.014
hormone transport GO:0009914 2 0.014
pigment granule localization GO:0051875 25 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
rna localization GO:0006403 4 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
protein heterooligomerization GO:0051291 1 0.014
actin filament polymerization GO:0030041 2 0.014
phagocytosis engulfment GO:0006911 1 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
post embryonic organ development GO:0048569 4 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
regulation of cell shape GO:0008360 1 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
localization of cell GO:0051674 244 0.014
compound eye development GO:0048749 2 0.014
cellular response to nutrient levels GO:0031669 2 0.014
response to topologically incorrect protein GO:0035966 2 0.014
olfactory lobe development GO:0021988 4 0.014
response to external stimulus GO:0009605 264 0.014
regulation of developmental process GO:0050793 247 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
regulation of neurotransmitter secretion GO:0046928 1 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
entrainment of circadian clock GO:0009649 2 0.014
negative regulation of biological process GO:0048519 304 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
adherens junction organization GO:0034332 4 0.014
stem cell division GO:0017145 1 0.013
stem cell proliferation GO:0072089 4 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
cellular response to external stimulus GO:0071496 2 0.013
interspecies interaction between organisms GO:0044419 4 0.013
regulation of transporter activity GO:0032409 2 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
heterocycle metabolic process GO:0046483 290 0.013
lipid catabolic process GO:0016042 4 0.013
antimicrobial humoral response GO:0019730 2 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
hormone secretion GO:0046879 2 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
regulation of biosynthetic process GO:0009889 250 0.013
regulation of sequestering of calcium ion GO:0051282 4 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
response to uv GO:0009411 3 0.013
regulation of signaling GO:0023051 235 0.013
nuclear export GO:0051168 1 0.013
positive regulation of immune effector process GO:0002699 3 0.013
camera type eye development GO:0043010 222 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of inflammatory response GO:0050727 2 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
cellular response to starvation GO:0009267 1 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
cell projection morphogenesis GO:0048858 244 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
biosynthetic process GO:0009058 294 0.012
response to alkaloid GO:0043279 2 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
response to stress GO:0006950 263 0.012
smooth muscle contraction GO:0006939 2 0.012
ion transmembrane transport GO:0034220 91 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
rna metabolic process GO:0016070 219 0.012
l amino acid transport GO:0015807 1 0.012
regulation of gtpase activity GO:0043087 2 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
fertilization GO:0009566 3 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
single fertilization GO:0007338 3 0.012
system process GO:0003008 185 0.012
chemosensory behavior GO:0007635 1 0.012
blood vessel development GO:0001568 246 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
ion transport GO:0006811 114 0.012
response to monosaccharide GO:0034284 3 0.012
peptide transport GO:0015833 1 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
transmembrane transport GO:0055085 120 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
response to amino acid GO:0043200 2 0.012
multi organism cellular process GO:0044764 2 0.012
response to glucose GO:0009749 3 0.012
brain development GO:0007420 293 0.012
protein dephosphorylation GO:0006470 3 0.011
response to antibiotic GO:0046677 1 0.011
regulation of protein polymerization GO:0032271 2 0.011
membrane invagination GO:0010324 1 0.011
axonogenesis GO:0007409 152 0.011
protein stabilization GO:0050821 2 0.011
positive regulation of biological process GO:0048518 253 0.011
vacuolar transport GO:0007034 2 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
regulation of ph GO:0006885 3 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
membrane hyperpolarization GO:0060081 1 0.011
forebrain development GO:0030900 96 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
leukocyte proliferation GO:0070661 1 0.011
actin filament based movement GO:0030048 1 0.011
single organism organelle organization GO:1902589 199 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
somatic stem cell maintenance GO:0035019 1 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
hemopoiesis GO:0030097 183 0.011
regulation of cellular ph GO:0030641 1 0.011
cytoplasm organization GO:0007028 4 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
negative regulation of reproductive process GO:2000242 3 0.011
positive regulation of epithelial cell differentiation GO:0030858 2 0.011
tube morphogenesis GO:0035239 349 0.011
pigmentation GO:0043473 85 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
tissue remodeling GO:0048771 4 0.011
retinal rod cell development GO:0046548 4 0.011
cell motility GO:0048870 244 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
cell migration GO:0016477 237 0.011
generation of neurons GO:0048699 385 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
positive regulation of reproductive process GO:2000243 2 0.011
sensory perception of smell GO:0007608 2 0.011
regulation of cell communication GO:0010646 232 0.011
b cell activation GO:0042113 2 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
superoxide metabolic process GO:0006801 2 0.010
regulation of sodium ion transport GO:0002028 2 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
regulation of primary metabolic process GO:0080090 311 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
regulation of cell projection assembly GO:0060491 4 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
golgi vesicle transport GO:0048193 3 0.010
nucleobase containing compound biosynthetic process GO:0034654 205 0.010
cellular response to light stimulus GO:0071482 4 0.010
positive regulation of cytokine production GO:0001819 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010

rbl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
nervous system disease DOID:863 0 0.029
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.015
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.012
immune system disease DOID:2914 0 0.011
cardiovascular system disease DOID:1287 0 0.011
sensory system disease DOID:0050155 0 0.010