Danio rerio

0 known processes

cldnk

claudin k

(Aliases: zgc:91878)

cldnk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nitrogen compound metabolic process GO:0051171 251 0.324
biosynthetic process GO:0009058 294 0.310
circadian sleep wake cycle process GO:0022410 2 0.276
organic substance biosynthetic process GO:1901576 289 0.271
brain development GO:0007420 293 0.250
long chain fatty acid metabolic process GO:0001676 1 0.228
oligodendrocyte differentiation GO:0048709 23 0.207
generation of neurons GO:0048699 385 0.205
central nervous system myelination GO:0022010 2 0.204
regulation of circadian rhythm GO:0042752 4 0.200
cation transmembrane transport GO:0098655 65 0.190
regulation of biosynthetic process GO:0009889 250 0.186
regulation of rna biosynthetic process GO:2001141 213 0.178
cellular biosynthetic process GO:0044249 286 0.175
heterocycle biosynthetic process GO:0018130 215 0.169
head development GO:0060322 303 0.159
larval development GO:0002164 2 0.153
circadian sleep wake cycle GO:0042745 2 0.144
startle response GO:0001964 4 0.142
nitrogen compound metabolic process GO:0006807 319 0.141
single organism metabolic process GO:0044710 217 0.141
nucleic acid templated transcription GO:0097659 181 0.140
regulation of circadian sleep wake cycle GO:0042749 1 0.139
organic cyclic compound biosynthetic process GO:1901362 223 0.139
response to alkaloid GO:0043279 2 0.133
aging GO:0007568 2 0.130
neuron differentiation GO:0030182 353 0.128
sensory system development GO:0048880 76 0.125
Zebrafish
circadian sleep wake cycle sleep GO:0050802 1 0.125
regulation of primary metabolic process GO:0080090 311 0.118
midbrain development GO:0030901 28 0.112
adult behavior GO:0030534 2 0.110
glial cell differentiation GO:0010001 42 0.110
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.108
regulation of macromolecule biosynthetic process GO:0010556 225 0.107
system process GO:0003008 185 0.105
inner ear development GO:0048839 126 0.104
regulation of multicellular organismal development GO:2000026 223 0.103
cell surface receptor signaling pathway GO:0007166 325 0.101
ear development GO:0043583 127 0.098
organic cyclic compound metabolic process GO:1901360 301 0.098
regulation of nucleic acid templated transcription GO:1903506 213 0.096
regulation of blood pressure GO:0008217 1 0.093
neuron development GO:0048666 262 0.093
tube morphogenesis GO:0035239 349 0.092
Zebrafish
regulation of gene expression GO:0010468 265 0.091
regulation of cell differentiation GO:0045595 142 0.091
rna metabolic process GO:0016070 219 0.087
aromatic compound biosynthetic process GO:0019438 217 0.086
regulation of macromolecule metabolic process GO:0060255 317 0.085
cellular component morphogenesis GO:0032989 336 0.083
digestive tract morphogenesis GO:0048546 231 0.078
Zebrafish
astrocyte differentiation GO:0048708 1 0.076
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.070
cellular aromatic compound metabolic process GO:0006725 295 0.069
cellular macromolecule biosynthetic process GO:0034645 224 0.069
reflex GO:0060004 2 0.069
gene expression GO:0010467 252 0.068
hormone transport GO:0009914 2 0.067
heterocycle metabolic process GO:0046483 290 0.067
axon ensheathment in central nervous system GO:0032291 2 0.065
establishment of localization GO:0051234 244 0.063
Zebrafish
cellular lipid metabolic process GO:0044255 36 0.063
positive regulation of catabolic process GO:0009896 4 0.062
cellular nitrogen compound metabolic process GO:0034641 290 0.062
long chain fatty acid biosynthetic process GO:0042759 1 0.062
positive regulation of cellular catabolic process GO:0031331 3 0.060
small molecule metabolic process GO:0044281 77 0.060
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.059
nucleobase containing compound biosynthetic process GO:0034654 205 0.057
rna biosynthetic process GO:0032774 181 0.057
gtp catabolic process GO:0006184 2 0.056
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.055
nucleobase containing compound metabolic process GO:0006139 274 0.055
organonitrogen compound metabolic process GO:1901564 74 0.054
transcription dna templated GO:0006351 181 0.054
inorganic cation transmembrane transport GO:0098662 50 0.053
regulation of metabolic process GO:0019222 359 0.053
heart development GO:0007507 313 0.053
lateral line development GO:0048882 66 0.052
Zebrafish
cell morphogenesis GO:0000902 289 0.051
response to chemical GO:0042221 320 0.051
amine metabolic process GO:0009308 2 0.049
positive regulation of nucleotide catabolic process GO:0030813 1 0.048
signal transduction GO:0007165 455 0.047
regulation of nucleotide biosynthetic process GO:0030808 15 0.047
regulation of developmental process GO:0050793 247 0.045
central nervous system development GO:0007417 387 0.045
tissue regeneration GO:0042246 74 0.044
positive regulation of transport GO:0051050 2 0.044
response to organic substance GO:0010033 153 0.044
transmission of nerve impulse GO:0019226 19 0.044
regulation of cellular biosynthetic process GO:0031326 245 0.043
membrane repolarization GO:0086009 2 0.042
inorganic ion transmembrane transport GO:0098660 57 0.042
ion transmembrane transport GO:0034220 91 0.042
positive regulation of gtp catabolic process GO:0033126 1 0.042
hormone secretion GO:0046879 2 0.041
regulation of multicellular organismal process GO:0051239 277 0.041
regulation of cell shape GO:0008360 1 0.040
ear morphogenesis GO:0042471 64 0.040
cellular amine metabolic process GO:0044106 2 0.040
neuromast development GO:0048884 46 0.039
Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.039
gliogenesis GO:0042063 45 0.039
regulation of oligodendrocyte differentiation GO:0048713 1 0.038
toxin metabolic process GO:0009404 1 0.038
synaptic transmission GO:0007268 35 0.038
sleep GO:0030431 1 0.036
proteasomal protein catabolic process GO:0010498 2 0.036
positive regulation of gtpase activity GO:0043547 1 0.036
response to transition metal nanoparticle GO:1990267 28 0.034
developmental maturation GO:0021700 34 0.033
regulation of biological quality GO:0065008 263 0.032
pigmentation GO:0043473 85 0.032
regulation of membrane potential GO:0042391 23 0.032
neuron projection development GO:0031175 180 0.031
circulatory system process GO:0003013 87 0.031
regulation of protein complex assembly GO:0043254 3 0.031
positive regulation of macromolecule metabolic process GO:0010604 93 0.031
cellular response to xenobiotic stimulus GO:0071466 35 0.031
exocytosis GO:0006887 1 0.031
regionalization GO:0003002 274 0.031
regulation of neurogenesis GO:0050767 87 0.031
fatty acid biosynthetic process GO:0006633 4 0.030
regulation of hormone secretion GO:0046883 2 0.030
cellular component biogenesis GO:0044085 178 0.030
positive regulation of nucleoside metabolic process GO:0045979 1 0.030
epiboly GO:0090504 41 0.030
Zebrafish
positive regulation of secretion GO:0051047 1 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.030
muscle structure development GO:0061061 196 0.029
response to drug GO:0042493 3 0.029
negative regulation of protein phosphorylation GO:0001933 4 0.029
single organism biosynthetic process GO:0044711 71 0.028
response to xenobiotic stimulus GO:0009410 45 0.028
neuronal action potential GO:0019228 18 0.028
oligodendrocyte development GO:0014003 7 0.028
ribonucleotide metabolic process GO:0009259 27 0.027
neuron projection morphogenesis GO:0048812 161 0.027
response to nicotine GO:0035094 2 0.027
regulation of glial cell differentiation GO:0045685 4 0.027
cell recognition GO:0008037 19 0.027
cellular nitrogen compound biosynthetic process GO:0044271 218 0.026
regulation of reproductive process GO:2000241 4 0.026
regulation of anatomical structure morphogenesis GO:0022603 130 0.026
response to oxygen containing compound GO:1901700 55 0.026
retina development in camera type eye GO:0060041 146 0.026
regulation of rna metabolic process GO:0051252 224 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
multicellular organismal signaling GO:0035637 22 0.025
negative regulation of blood circulation GO:1903523 2 0.025
muscle cell differentiation GO:0042692 139 0.025
maintenance of location GO:0051235 4 0.025
cellular macromolecule metabolic process GO:0044260 391 0.024
skeletal muscle tissue development GO:0007519 67 0.024
localization of cell GO:0051674 244 0.024
regulation of neurotransmitter transport GO:0051588 1 0.024
regulation of cellular component organization GO:0051128 86 0.024
positive regulation of blood circulation GO:1903524 2 0.024
carbohydrate derivative biosynthetic process GO:1901137 43 0.023
chemosensory behavior GO:0007635 1 0.023
action potential GO:0001508 19 0.023
regulation of ph GO:0006885 3 0.023
vasculature development GO:0001944 278 0.023
inositol lipid mediated signaling GO:0048017 2 0.023
glomerular visceral epithelial cell fate commitment GO:0072149 4 0.023
nucleoside phosphate metabolic process GO:0006753 28 0.023
cellular biogenic amine metabolic process GO:0006576 2 0.023
neurotransmitter transport GO:0006836 2 0.023
negative regulation of reproductive process GO:2000242 3 0.023
regulation of response to stimulus GO:0048583 269 0.022
cellular response to oxygen levels GO:0071453 1 0.022
gastrulation GO:0007369 208 0.022
Zebrafish
negative regulation of signaling GO:0023057 96 0.022
nucleotide metabolic process GO:0009117 28 0.022
regulation of cellular ph GO:0030641 1 0.022
response to food GO:0032094 1 0.022
purine ribonucleotide biosynthetic process GO:0009152 20 0.021
cell cell signaling GO:0007267 52 0.021
cell projection organization GO:0030030 284 0.021
negative regulation of cellular process GO:0048523 283 0.020
muscle cell development GO:0055001 115 0.020
axon development GO:0061564 166 0.020
cell cycle GO:0007049 93 0.020
striated muscle tissue development GO:0014706 110 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
single organism nuclear import GO:1902593 3 0.020
sodium ion transport GO:0006814 24 0.020
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.019
positive regulation of biological process GO:0048518 253 0.019
purine nucleotide metabolic process GO:0006163 27 0.019
multi organism process GO:0051704 134 0.019
posterior lateral line nerve glial cell development GO:0048941 5 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
cognition GO:0050890 1 0.019
facial nerve morphogenesis GO:0021610 1 0.019
regulation of cell morphogenesis GO:0022604 42 0.019
macromolecule biosynthetic process GO:0009059 227 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
organic acid metabolic process GO:0006082 31 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
sensory organ morphogenesis GO:0090596 200 0.018
cell part morphogenesis GO:0032990 246 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
neuron death GO:0070997 21 0.018
cytokinesis GO:0000910 3 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
regulation of cell communication GO:0010646 232 0.018
embryonic organ development GO:0048568 381 0.018
multicellular organism growth GO:0035264 4 0.018
actin filament based process GO:0030029 64 0.018
semicircular canal development GO:0060872 24 0.017
cellular ketone metabolic process GO:0042180 11 0.017
myelination GO:0042552 18 0.017
heart contraction GO:0060047 71 0.017
blood circulation GO:0008015 87 0.017
single organism localization GO:1902578 225 0.017
Zebrafish
positive regulation of lyase activity GO:0051349 6 0.017
regulation of signaling GO:0023051 235 0.017
organelle assembly GO:0070925 110 0.017
nucleic acid metabolic process GO:0090304 244 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
sensory perception GO:0007600 39 0.017
transport GO:0006810 220 0.017
Zebrafish
camera type eye development GO:0043010 222 0.016
positive regulation of cyclase activity GO:0031281 6 0.016
meiotic nuclear division GO:0007126 4 0.016
response to external stimulus GO:0009605 264 0.016
muscle organ development GO:0007517 101 0.016
organelle organization GO:0006996 227 0.016
regulation of neuronal synaptic plasticity GO:0048168 1 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
macromolecular complex disassembly GO:0032984 1 0.016
developmental growth GO:0048589 166 0.016
protein complex disassembly GO:0043241 1 0.015
carboxylic acid biosynthetic process GO:0046394 12 0.015
cellular response to organic substance GO:0071310 105 0.015
nucleoside phosphate biosynthetic process GO:1901293 21 0.015
monovalent inorganic cation transport GO:0015672 42 0.015
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.015
inner ear morphogenesis GO:0042472 63 0.015
digestive system development GO:0055123 289 0.015
Zebrafish
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
response to hormone GO:0009725 48 0.015
eye development GO:0001654 277 0.015
response to endogenous stimulus GO:0009719 83 0.015
regulation of filopodium assembly GO:0051489 2 0.015
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.015
signal transduction in absence of ligand GO:0038034 1 0.015
heart morphogenesis GO:0003007 156 0.015
embryonic viscerocranium morphogenesis GO:0048703 52 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
ph reduction GO:0045851 1 0.015
transmembrane transport GO:0055085 120 0.015
sensory organ development GO:0007423 393 0.014
Zebrafish
cellular response to unfolded protein GO:0034620 2 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
Zebrafish
regulation of localization GO:0032879 104 0.014
Zebrafish
oxoacid metabolic process GO:0043436 31 0.014
lateral line nerve glial cell morphogenesis involved in differentiation GO:0048938 5 0.014
hindbrain development GO:0030902 91 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
positive regulation of cgmp metabolic process GO:0030825 6 0.014
gtp metabolic process GO:0046039 4 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
morphogenesis of an epithelial sheet GO:0002011 49 0.014
Zebrafish
smooth muscle contraction GO:0006939 2 0.014
specification of symmetry GO:0009799 204 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
locomotion GO:0040011 313 0.014
nitrogen compound transport GO:0071705 23 0.014
regulation of cell development GO:0060284 100 0.014
monoamine transport GO:0015844 1 0.013
cytoskeleton organization GO:0007010 96 0.013
positive regulation of cell division GO:0051781 2 0.013
regulation of blood vessel size GO:0050880 2 0.013
wound healing GO:0042060 90 0.013
positive regulation of developmental process GO:0051094 50 0.013
peptide transport GO:0015833 1 0.013
actin filament polymerization GO:0030041 2 0.013
protein depolymerization GO:0051261 1 0.013
positive regulation of gene expression GO:0010628 71 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
regulation of inflammatory response GO:0050727 2 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
peripheral nervous system development GO:0007422 55 0.013
cellular protein catabolic process GO:0044257 4 0.013
skeletal muscle organ development GO:0060538 78 0.013
protein localization to nucleus GO:0034504 3 0.013
compound eye development GO:0048749 2 0.013
response to amine GO:0014075 1 0.013
negative regulation of secretion GO:0051048 2 0.013
mechanosensory lateral line system development GO:0048881 49 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.013
vesicle localization GO:0051648 27 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
regulation of tube size GO:0035150 2 0.012
response to glucose GO:0009749 3 0.012
positive regulation of cyclic nucleotide metabolic process GO:0030801 8 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
intracellular signal transduction GO:0035556 85 0.012
myelination of lateral line nerve axons GO:0048897 5 0.012
nucleotide biosynthetic process GO:0009165 21 0.012
spermatid development GO:0007286 2 0.012
cellular response to organic cyclic compound GO:0071407 38 0.012
regulation of exocytosis GO:0017157 1 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
antimicrobial humoral response GO:0019730 2 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
monocarboxylic acid biosynthetic process GO:0072330 12 0.012
cellular localization GO:0051641 97 0.012
oxidative demethylation GO:0070989 1 0.012
response to monosaccharide GO:0034284 3 0.012
response to nitrogen compound GO:1901698 19 0.012
cell migration GO:0016477 237 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
spermatid differentiation GO:0048515 2 0.011
fatty acid transport GO:0015908 1 0.011
regulation of protein polymerization GO:0032271 2 0.011
regulation of sodium ion transport GO:0002028 2 0.011
Zebrafish
protein metabolic process GO:0019538 183 0.011
otolith formation GO:0032475 2 0.011
lateral line system development GO:0048925 76 0.011
Zebrafish
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
regulation of intracellular ph GO:0051453 1 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
cellular sodium ion homeostasis GO:0006883 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
endocrine process GO:0050886 2 0.011
protein polymerization GO:0051258 4 0.011
otic vesicle development GO:0071599 42 0.011
establishment of vesicle localization GO:0051650 24 0.011
single organism organelle organization GO:1902589 199 0.011
regulation of guanylate cyclase activity GO:0031282 6 0.011
protein import GO:0017038 3 0.010
actomyosin structure organization GO:0031032 53 0.010
response to metal ion GO:0010038 34 0.010
cellular component assembly GO:0022607 170 0.010
axon ensheathment GO:0008366 18 0.010
sodium ion transmembrane transport GO:0035725 21 0.010
synaptic vesicle localization GO:0097479 1 0.010
regulation of protein catabolic process GO:0042176 1 0.010

cldnk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.019
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
cerebral degeneration DOID:1443 0 0.011
central nervous system disease DOID:331 0 0.011
brain disease DOID:936 0 0.011
leukodystrophy DOID:10579 0 0.011