Danio rerio

18 known processes

lta

lymphotoxin alpha (TNF superfamily, member 1)

(Aliases: TNF-N)

lta biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.074
larval development GO:0002164 2 0.056
positive regulation of transport GO:0051050 2 0.048
maintenance of location GO:0051235 4 0.047
phagocytosis GO:0006909 3 0.040
establishment of localization GO:0051234 244 0.036
lipid storage GO:0019915 1 0.034
response to drug GO:0042493 3 0.034
protein localization to nucleus GO:0034504 3 0.033
regulation of establishment of protein localization GO:0070201 4 0.032
regulation of multicellular organism growth GO:0040014 4 0.031
single organism localization GO:1902578 225 0.031
nucleocytoplasmic transport GO:0006913 4 0.030
multicellular organism growth GO:0035264 4 0.030
regulation of protein localization to nucleus GO:1900180 2 0.029
transport GO:0006810 220 0.029
regulation of cytokine production GO:0001817 3 0.029
nuclear transport GO:0051169 4 0.027
signal transduction GO:0007165 455 0.027
response to chemical GO:0042221 320 0.027
regulation of metabolic process GO:0019222 359 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
regulation of production of molecular mediator of immune response GO:0002700 1 0.027
regulation of blood pressure GO:0008217 1 0.026
response to external stimulus GO:0009605 264 0.026
regulation of protein transport GO:0051223 3 0.026
secondary metabolic process GO:0019748 3 0.026
cytokinesis GO:0000910 3 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.025
protein import GO:0017038 3 0.025
single organism nuclear import GO:1902593 3 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.024
sensory perception of chemical stimulus GO:0007606 3 0.024
immunoglobulin mediated immune response GO:0016064 3 0.024
amine metabolic process GO:0009308 2 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
nuclear import GO:0051170 3 0.024
immune system process GO:0002376 241 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
regulation of cell activation GO:0050865 1 0.023
chemosensory behavior GO:0007635 1 0.023
tube morphogenesis GO:0035239 349 0.023
positive regulation of cell cycle GO:0045787 3 0.023
positive regulation of immune effector process GO:0002699 3 0.023
response to carbohydrate GO:0009743 3 0.023
regulation of cytoplasmic transport GO:1903649 4 0.022
protein import into nucleus GO:0006606 3 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
positive regulation of catabolic process GO:0009896 4 0.022
regulation of biological quality GO:0065008 263 0.022
nitrogen compound metabolic process GO:0006807 319 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
cellular response to external stimulus GO:0071496 2 0.022
heterocycle metabolic process GO:0046483 290 0.022
organic substance biosynthetic process GO:1901576 289 0.022
mononuclear cell proliferation GO:0032943 1 0.022
organonitrogen compound metabolic process GO:1901564 74 0.021
gtp metabolic process GO:0046039 4 0.021
regulation of hormone secretion GO:0046883 2 0.021
regionalization GO:0003002 274 0.021
peptide transport GO:0015833 1 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
leukocyte proliferation GO:0070661 1 0.021
production of molecular mediator of immune response GO:0002440 2 0.021
organic acid metabolic process GO:0006082 31 0.021
cellular nitrogen compound metabolic process GO:0034641 290 0.021
cellular amine metabolic process GO:0044106 2 0.020
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
water transport GO:0006833 15 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
inositol lipid mediated signaling GO:0048017 2 0.020
protein targeting to nucleus GO:0044744 3 0.020
regulation of gene expression GO:0010468 265 0.020
female gonad development GO:0008585 4 0.020
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.020
response to stress GO:0006950 263 0.020
response to monosaccharide GO:0034284 3 0.020
regulation of synapse assembly GO:0051963 3 0.020
hormone secretion GO:0046879 2 0.020
stem cell maintenance GO:0019827 4 0.020
meiotic cell cycle process GO:1903046 3 0.020
regulation of metal ion transport GO:0010959 4 0.020
female sex differentiation GO:0046660 4 0.019
oxoacid metabolic process GO:0043436 31 0.019
transmembrane transport GO:0055085 120 0.019
regulation of protein targeting GO:1903533 2 0.019
regulation of protein import into nucleus GO:0042306 2 0.019
hormone transport GO:0009914 2 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
cellular ketone metabolic process GO:0042180 11 0.019
mitochondrion organization GO:0007005 4 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
biosynthetic process GO:0009058 294 0.019
gtp catabolic process GO:0006184 2 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
system process GO:0003008 185 0.019
vasculature development GO:0001944 278 0.019
positive regulation of cytokine production GO:0001819 2 0.018
positive regulation of secretion GO:0051047 1 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
growth GO:0040007 174 0.018
phosphatidylinositol mediated signaling GO:0048015 2 0.018
stem cell proliferation GO:0072089 4 0.018
response to hexose GO:0009746 3 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
gene expression GO:0010467 252 0.018
single organism metabolic process GO:0044710 217 0.018
cellular protein catabolic process GO:0044257 4 0.018
gastrulation GO:0007369 208 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
response to external biotic stimulus GO:0043207 97 0.018
protein acetylation GO:0006473 2 0.018
interspecies interaction between organisms GO:0044419 4 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
lymphocyte proliferation GO:0046651 1 0.017
response to other organism GO:0051707 97 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
negative regulation of kinase activity GO:0033673 4 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
regulation of blood vessel size GO:0050880 2 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
regulation of reproductive process GO:2000241 4 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
brain development GO:0007420 293 0.017
digestive tract development GO:0048565 265 0.017
b cell mediated immunity GO:0019724 3 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
protein acylation GO:0043543 3 0.017
protein metabolic process GO:0019538 183 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
meiotic nuclear division GO:0007126 4 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
neurotransmitter transport GO:0006836 2 0.017
central nervous system development GO:0007417 387 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
positive regulation of cell activation GO:0050867 1 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
negative regulation of cellular process GO:0048523 283 0.016
response to nutrient GO:0007584 3 0.016
regulation of tube size GO:0035150 2 0.016
regulation of protein catabolic process GO:0042176 1 0.016
negative regulation of catabolic process GO:0009895 3 0.016
specification of symmetry GO:0009799 204 0.016
response to glucose GO:0009749 3 0.016
cellular amide metabolic process GO:0043603 4 0.016
phagocytosis engulfment GO:0006911 1 0.016
regulation of inflammatory response GO:0050727 2 0.016
amino acid transport GO:0006865 2 0.016
protein heterooligomerization GO:0051291 1 0.016
regulation of circadian rhythm GO:0042752 4 0.016
small molecule metabolic process GO:0044281 77 0.016
anterior posterior pattern specification GO:0009952 152 0.016
b cell activation GO:0042113 2 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
regulation of sodium ion transport GO:0002028 2 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
regulation of primary metabolic process GO:0080090 311 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
single organism transport GO:0044765 206 0.015
endocrine process GO:0050886 2 0.015
endocrine hormone secretion GO:0060986 2 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
negative regulation of biological process GO:0048519 304 0.015
protein secretion GO:0009306 1 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
compound eye development GO:0048749 2 0.015
positive regulation of biological process GO:0048518 253 0.015
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
regulation of signaling GO:0023051 235 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
ion transmembrane transport GO:0034220 91 0.015
meiotic chromosome segregation GO:0045132 3 0.015
regulation of response to stimulus GO:0048583 269 0.015
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.015
regulation of binding GO:0051098 3 0.015
autophagy GO:0006914 4 0.015
response to corticosteroid GO:0031960 1 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
neurotransmitter secretion GO:0007269 2 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
digestive system development GO:0055123 289 0.015
positive regulation of cell killing GO:0031343 2 0.015
digestive tract morphogenesis GO:0048546 231 0.015
regulation of developmental process GO:0050793 247 0.015
response to organic substance GO:0010033 153 0.015
translational initiation GO:0006413 3 0.015
membrane invagination GO:0010324 1 0.015
xenobiotic metabolic process GO:0006805 4 0.015
rna localization GO:0006403 4 0.015
cellular response to nutrient levels GO:0031669 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
sequestering of metal ion GO:0051238 3 0.015
adherens junction organization GO:0034332 4 0.015
determination of bilateral symmetry GO:0009855 204 0.014
adult behavior GO:0030534 2 0.014
cellular component disassembly GO:0022411 1 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
protein localization to plasma membrane GO:0072659 1 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
regulation of synapse organization GO:0050807 3 0.014
cellular response to starvation GO:0009267 1 0.014
cell morphogenesis GO:0000902 289 0.014
nucleic acid templated transcription GO:0097659 181 0.014
response to biotic stimulus GO:0009607 97 0.014
positive regulation of cell division GO:0051781 2 0.013
negative regulation of protein localization to nucleus GO:1900181 2 0.013
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.013
post embryonic organ development GO:0048569 4 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
rna metabolic process GO:0016070 219 0.013
cellular biosynthetic process GO:0044249 286 0.013
heart development GO:0007507 313 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
membrane fusion GO:0061025 2 0.013
regulation of protein complex assembly GO:0043254 3 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
protein complex disassembly GO:0043241 1 0.013
cognition GO:0050890 1 0.013
neuron differentiation GO:0030182 353 0.013
small molecule catabolic process GO:0044282 3 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
embryonic organ development GO:0048568 381 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
cellular component movement GO:0006928 335 0.013
cellular component morphogenesis GO:0032989 336 0.013
single organism organelle organization GO:1902589 199 0.013
sleep GO:0030431 1 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
organelle assembly GO:0070925 110 0.013
calcium ion transport into cytosol GO:0060402 3 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
single organism membrane fusion GO:0044801 2 0.013
detection of chemical stimulus GO:0009593 4 0.013
regulation of cell communication GO:0010646 232 0.013
blood vessel morphogenesis GO:0048514 216 0.013
cytoplasm organization GO:0007028 4 0.013
sequestering of calcium ion GO:0051208 3 0.013
developmental programmed cell death GO:0010623 4 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
regulation of endocrine process GO:0044060 2 0.013
nucleic acid metabolic process GO:0090304 244 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
positive regulation of leukocyte mediated immunity GO:0002705 1 0.013
cellular response to radiation GO:0071478 4 0.013
urea transport GO:0015840 11 0.012
ion transport GO:0006811 114 0.012
spermatid differentiation GO:0048515 2 0.012
atp catabolic process GO:0006200 4 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
cell killing GO:0001906 2 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
blood vessel development GO:0001568 246 0.012
generation of neurons GO:0048699 385 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
regulation of muscle contraction GO:0006937 3 0.012
regulation of transporter activity GO:0032409 2 0.012
protein stabilization GO:0050821 2 0.012
complement activation GO:0006956 3 0.012
cell migration GO:0016477 237 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
endosomal transport GO:0016197 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
immune system development GO:0002520 191 0.012
sensory organ development GO:0007423 393 0.012
negative regulation of nuclear division GO:0051784 3 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
protein homooligomerization GO:0051260 3 0.012
positive regulation of cellular process GO:0048522 201 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
regulation of skeletal muscle fiber development GO:0048742 2 0.012
macromolecular complex disassembly GO:0032984 1 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
cellular response to light stimulus GO:0071482 4 0.012
cation transmembrane transport GO:0098655 65 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
rna biosynthetic process GO:0032774 181 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
somitogenesis GO:0001756 87 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
positive regulation of histone modification GO:0031058 1 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
lipid catabolic process GO:0016042 4 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
transcription dna templated GO:0006351 181 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
positive regulation of reproductive process GO:2000243 2 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
zymogen activation GO:0031638 3 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
regulation of ph GO:0006885 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.011
polyol transport GO:0015791 7 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
response to vitamin GO:0033273 3 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
regulation of signal transduction GO:0009966 225 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
hemopoiesis GO:0030097 183 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
regulation of autophagy GO:0010506 3 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
sensory perception of smell GO:0007608 2 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
spermatid development GO:0007286 2 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
multi organism process GO:0051704 134 0.011
intracellular mrna localization GO:0008298 1 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
cellular component biogenesis GO:0044085 178 0.011
somite development GO:0061053 96 0.011
cell projection organization GO:0030030 284 0.011
head development GO:0060322 303 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
cell substrate adhesion GO:0031589 4 0.011
response to glucocorticoid GO:0051384 1 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
determination of left right symmetry GO:0007368 179 0.011
cellular localization GO:0051641 97 0.011
regulation of dna replication GO:0006275 3 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
negative regulation of cytokine production GO:0001818 1 0.011
regulation of organelle assembly GO:1902115 4 0.011
response to bacterium GO:0009617 58 0.011
dicarboxylic acid transport GO:0006835 1 0.011
epithelial cell differentiation GO:0030855 116 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
tissue remodeling GO:0048771 4 0.011
nucleobase containing compound metabolic process GO:0006139 274 0.011
regulation of cell shape GO:0008360 1 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
actin filament polymerization GO:0030041 2 0.011
somatic stem cell maintenance GO:0035019 1 0.011
angiogenesis GO:0001525 158 0.011
negative regulation of reproductive process GO:2000242 3 0.011
response to uv GO:0009411 3 0.011
positive regulation of myeloid cell differentiation GO:0045639 2 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
glucose homeostasis GO:0042593 1 0.011
negative regulation of secretion GO:0051048 2 0.011
regulation of localization GO:0032879 104 0.011
immunoglobulin production GO:0002377 1 0.011
antimicrobial humoral response GO:0019730 2 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
peptide metabolic process GO:0006518 1 0.011
regulation of leukocyte mediated immunity GO:0002703 1 0.010
release of sequestered calcium ion into cytosol GO:0051209 3 0.010
leukocyte mediated cytotoxicity GO:0001909 1 0.010
somatic muscle development GO:0007525 4 0.010
negative regulation of defense response GO:0031348 2 0.010
fertilization GO:0009566 3 0.010
carboxylic acid catabolic process GO:0046395 3 0.010
developmental growth GO:0048589 166 0.010
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
positive regulation of leukocyte differentiation GO:1902107 1 0.010
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
ventricular cardiac muscle tissue development GO:0003229 3 0.010
regulation of rna metabolic process GO:0051252 224 0.010
segmentation GO:0035282 97 0.010
homeostatic process GO:0042592 142 0.010
inorganic anion transport GO:0015698 25 0.010
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
response to amino acid GO:0043200 2 0.010
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.010
cellular lipid catabolic process GO:0044242 3 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
locomotion GO:0040011 313 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
cellular component assembly GO:0022607 170 0.010
multi organism cellular process GO:0044764 2 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
golgi vesicle transport GO:0048193 3 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
organelle fusion GO:0048284 3 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010

lta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
musculoskeletal system disease DOID:17 0 0.020
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
cardiovascular system disease DOID:1287 0 0.011
disease of metabolism DOID:0014667 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
muscular disease DOID:0080000 0 0.011