Danio rerio

74 known processes

zeb2b

zinc finger E-box binding homeobox 2b

(Aliases: sip1b)

zeb2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chordate embryonic development GO:0043009 271 0.366
generation of neurons GO:0048699 385 0.320
cellular biosynthetic process GO:0044249 286 0.300
cellular component morphogenesis GO:0032989 336 0.242
gene expression GO:0010467 252 0.231
regulation of signal transduction GO:0009966 225 0.206
neuron differentiation GO:0030182 353 0.187
response to external stimulus GO:0009605 264 0.151
mesenchyme development GO:0060485 127 0.151
cellular macromolecule metabolic process GO:0044260 391 0.145
signal transduction GO:0007165 455 0.139
regulation of macromolecule metabolic process GO:0060255 317 0.137
axon development GO:0061564 166 0.136
regulation of multicellular organismal development GO:2000026 223 0.131
regulation of cell differentiation GO:0045595 142 0.124
neuron development GO:0048666 262 0.124
rna biosynthetic process GO:0032774 181 0.120
central nervous system development GO:0007417 387 0.116
regulation of reactive oxygen species metabolic process GO:2000377 2 0.106
organic cyclic compound biosynthetic process GO:1901362 223 0.105
regulation of nucleic acid templated transcription GO:1903506 213 0.102
sensory system development GO:0048880 76 0.100
regulation of signaling GO:0023051 235 0.097
positive regulation of cell communication GO:0010647 56 0.094
taxis GO:0042330 109 0.091
developmental growth involved in morphogenesis GO:0060560 86 0.088
morphogenesis of an epithelium GO:0002009 333 0.087
gastrulation GO:0007369 208 0.087
head development GO:0060322 303 0.086
regulation of developmental process GO:0050793 247 0.086
brain development GO:0007420 293 0.085
astrocyte differentiation GO:0048708 1 0.083
cell surface receptor signaling pathway GO:0007166 325 0.079
embryonic organ development GO:0048568 381 0.079
positive regulation of metabolic process GO:0009893 108 0.078
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.077
heart contraction GO:0060047 71 0.076
nitrogen compound metabolic process GO:0006807 319 0.074
embryo development ending in birth or egg hatching GO:0009792 271 0.073
cranial ganglion development GO:0061550 3 0.073
cellular macromolecule biosynthetic process GO:0034645 224 0.072
regulation of cellular biosynthetic process GO:0031326 245 0.071
macromolecule biosynthetic process GO:0009059 227 0.070
cellular aromatic compound metabolic process GO:0006725 295 0.070
single organism metabolic process GO:0044710 217 0.069
extrinsic apoptotic signaling pathway GO:0097191 3 0.067
aromatic compound biosynthetic process GO:0019438 217 0.067
inner ear receptor cell differentiation GO:0060113 29 0.067
cell morphogenesis involved in differentiation GO:0000904 195 0.066
nerve development GO:0021675 45 0.066
somite development GO:0061053 96 0.065
response to stress GO:0006950 263 0.064
segmentation GO:0035282 97 0.064
somitogenesis GO:0001756 87 0.063
nucleic acid templated transcription GO:0097659 181 0.062
hair cell differentiation GO:0035315 32 0.062
heterocycle metabolic process GO:0046483 290 0.061
positive regulation of rna biosynthetic process GO:1902680 57 0.060
cell projection morphogenesis GO:0048858 244 0.058
stem cell proliferation GO:0072089 4 0.056
neuron projection development GO:0031175 180 0.056
cytoskeleton organization GO:0007010 96 0.056
mesenchymal cell development GO:0014031 78 0.056
axonal defasciculation GO:0007414 2 0.055
embryonic organ morphogenesis GO:0048562 274 0.054
axonogenesis GO:0007409 152 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.052
regulation of multicellular organismal process GO:0051239 277 0.052
response to abiotic stimulus GO:0009628 122 0.051
oocyte maturation GO:0001556 4 0.051
regulation of metabolic process GO:0019222 359 0.051
negative regulation of biological process GO:0048519 304 0.050
transcription dna templated GO:0006351 181 0.049
regulation of cell communication GO:0010646 232 0.049
regulation of tube size GO:0035150 2 0.049
cranial nerve development GO:0021545 42 0.048
digestive system development GO:0055123 289 0.048
cell adhesion GO:0007155 40 0.047
stem cell development GO:0048864 82 0.047
apoptotic process GO:0006915 116 0.047
regulation of macromolecule biosynthetic process GO:0010556 225 0.047
death GO:0016265 121 0.047
cellular carbohydrate metabolic process GO:0044262 4 0.046
smooth muscle tissue development GO:0048745 1 0.046
positive regulation of multicellular organismal process GO:0051240 52 0.045
regulation of neurogenesis GO:0050767 87 0.044
sensory perception of chemical stimulus GO:0007606 3 0.044
tube morphogenesis GO:0035239 349 0.043
muscle fiber development GO:0048747 52 0.043
protein dephosphorylation GO:0006470 3 0.043
positive regulation of gene expression GO:0010628 71 0.043
response to glucose GO:0009749 3 0.042
organic substance biosynthetic process GO:1901576 289 0.042
mechanosensory lateral line system development GO:0048881 49 0.042
lateral line system development GO:0048925 76 0.041
embryonic skeletal system morphogenesis GO:0048704 93 0.041
response to corticosteroid GO:0031960 1 0.041
positive regulation of signal transduction GO:0009967 56 0.041
system process GO:0003008 185 0.041
regulation of neutrophil migration GO:1902622 6 0.041
cell part morphogenesis GO:0032990 246 0.041
biosynthetic process GO:0009058 294 0.040
positive regulation of biosynthetic process GO:0009891 68 0.040
vasculature development GO:0001944 278 0.040
pronephros development GO:0048793 69 0.039
regulation of gene expression GO:0010468 265 0.039
regulation of biosynthetic process GO:0009889 250 0.039
cellular nitrogen compound biosynthetic process GO:0044271 218 0.039
collateral sprouting in absence of injury GO:0048669 4 0.038
b cell differentiation GO:0030183 1 0.038
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.038
positive regulation of biological process GO:0048518 253 0.038
epithelial tube morphogenesis GO:0060562 148 0.038
regulation of collateral sprouting in absence of injury GO:0048696 4 0.038
female gonad development GO:0008585 4 0.037
regulation of rna biosynthetic process GO:2001141 213 0.037
regulation of programmed cell death GO:0043067 101 0.037
organic cyclic compound metabolic process GO:1901360 301 0.037
cell chemotaxis GO:0060326 17 0.036
negative regulation of cellular process GO:0048523 283 0.036
regulation of neuron migration GO:2001222 2 0.036
response to glucocorticoid GO:0051384 1 0.035
neurological system process GO:0050877 62 0.035
regulation of reproductive process GO:2000241 4 0.035
skeletal muscle tissue development GO:0007519 67 0.035
positive regulation of embryonic development GO:0040019 3 0.034
localization of cell GO:0051674 244 0.034
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.033
autonomic nervous system development GO:0048483 19 0.033
pigment cell differentiation GO:0050931 38 0.033
axon guidance GO:0007411 86 0.033
cellular response to nutrient levels GO:0031669 2 0.032
determination of heart left right asymmetry GO:0061371 117 0.032
actin filament based process GO:0030029 64 0.032
positive regulation of myeloid cell differentiation GO:0045639 2 0.031
biological adhesion GO:0022610 40 0.031
smooth muscle contraction GO:0006939 2 0.031
enteric nervous system development GO:0048484 12 0.030
regulation of nitrogen compound metabolic process GO:0051171 251 0.030
female sex differentiation GO:0046660 4 0.029
regulation of response to stimulus GO:0048583 269 0.029
peripheral nervous system neuron differentiation GO:0048934 28 0.029
response to light stimulus GO:0009416 46 0.029
regulation of cell death GO:0010941 103 0.029
regulation of rna metabolic process GO:0051252 224 0.029
regulation of neural precursor cell proliferation GO:2000177 3 0.029
amine metabolic process GO:0009308 2 0.028
muscle cell migration GO:0014812 4 0.028
transmission of nerve impulse GO:0019226 19 0.028
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.028
regulation of carbohydrate metabolic process GO:0006109 4 0.028
stem cell differentiation GO:0048863 117 0.028
cellular component assembly involved in morphogenesis GO:0010927 107 0.027
neural crest cell development GO:0014032 62 0.026
single organism biosynthetic process GO:0044711 71 0.026
mechanoreceptor differentiation GO:0042490 37 0.026
response to chemical GO:0042221 320 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
b cell activation GO:0042113 2 0.025
myofibril assembly GO:0030239 48 0.025
vasculogenesis GO:0001570 41 0.025
embryonic cranial skeleton morphogenesis GO:0048701 90 0.025
stem cell maintenance GO:0019827 4 0.025
single organism organelle organization GO:1902589 199 0.024
response to carbohydrate GO:0009743 3 0.024
cell cell adhesion involved in gastrulation GO:0070586 4 0.024
regulation of response to biotic stimulus GO:0002831 2 0.024
response to hexose GO:0009746 3 0.024
muscle cell development GO:0055001 115 0.024
cell cycle GO:0007049 93 0.023
production of molecular mediator of immune response GO:0002440 2 0.023
organelle organization GO:0006996 227 0.023
regulation of locomotion GO:0040012 55 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
cellular protein metabolic process GO:0044267 129 0.022
striated muscle tissue development GO:0014706 110 0.022
convergent extension GO:0060026 118 0.022
mitotic dna integrity checkpoint GO:0044774 4 0.022
mesenchymal cell differentiation GO:0048762 87 0.021
immune system development GO:0002520 191 0.021
phagocytosis GO:0006909 3 0.021
response to monosaccharide GO:0034284 3 0.021
regulation of heart growth GO:0060420 2 0.021
larval development GO:0002164 2 0.021
regulation of embryonic development GO:0045995 47 0.021
muscle cell differentiation GO:0042692 139 0.021
stem cell division GO:0017145 1 0.021
regulation of epithelial cell proliferation GO:0050678 3 0.021
negative regulation of multicellular organismal process GO:0051241 69 0.020
cellular response to endogenous stimulus GO:0071495 68 0.020
regulation of skeletal muscle tissue development GO:0048641 4 0.020
tissue migration GO:0090130 37 0.020
tube closure GO:0060606 1 0.020
protein modification process GO:0036211 100 0.020
response to nutrient GO:0007584 3 0.020
phosphorylation GO:0016310 69 0.020
positive regulation of catabolic process GO:0009896 4 0.020
retina development in camera type eye GO:0060041 146 0.020
mesoderm development GO:0007498 88 0.020
positive regulation of macromolecule metabolic process GO:0010604 93 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
branching morphogenesis of a nerve GO:0048755 4 0.019
programmed cell death GO:0012501 119 0.019
protein metabolic process GO:0019538 183 0.019
cellular response to external stimulus GO:0071496 2 0.019
embryonic epithelial tube formation GO:0001838 17 0.019
regulation of protein catabolic process GO:0042176 1 0.019
compound eye development GO:0048749 2 0.018
cell morphogenesis GO:0000902 289 0.018
locomotion GO:0040011 313 0.018
actomyosin structure organization GO:0031032 53 0.018
cell motility GO:0048870 244 0.018
positive regulation of cellular metabolic process GO:0031325 94 0.018
sodium ion import GO:0097369 3 0.018
neuron projection morphogenesis GO:0048812 161 0.018
embryonic skeletal joint morphogenesis GO:0060272 3 0.018
neuroblast proliferation GO:0007405 2 0.018
development of primary female sexual characteristics GO:0046545 4 0.018
chemotaxis GO:0006935 104 0.018
regulation of blood vessel size GO:0050880 2 0.018
central nervous system neuron axonogenesis GO:0021955 18 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
regulation of glial cell differentiation GO:0045685 4 0.018
centrosome cycle GO:0007098 1 0.018
cognition GO:0050890 1 0.018
cellular protein modification process GO:0006464 100 0.018
spermatid development GO:0007286 2 0.018
multicellular organismal response to stress GO:0033555 2 0.017
aging GO:0007568 2 0.017
action potential GO:0001508 19 0.017
ear morphogenesis GO:0042471 64 0.017
positive regulation of striated muscle cell differentiation GO:0051155 1 0.017
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.017
multicellular organismal signaling GO:0035637 22 0.017
rna metabolic process GO:0016070 219 0.017
negative regulation of cell differentiation GO:0045596 46 0.017
ganglion development GO:0061548 5 0.017
anterior lateral line development GO:0048899 5 0.017
ear development GO:0043583 127 0.017
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.017
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.017
negative regulation of bmp signaling pathway GO:0030514 13 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
directional locomotion GO:0033058 1 0.016
response to cold GO:0009409 4 0.016
cellular component biogenesis GO:0044085 178 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
positive regulation of neurogenesis GO:0050769 24 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
regulation of cellular extravasation GO:0002691 1 0.016
negative regulation of apoptotic process GO:0043066 55 0.016
regulation of apoptotic process GO:0042981 98 0.016
response to endogenous stimulus GO:0009719 83 0.016
cellular amide metabolic process GO:0043603 4 0.016
regulation of cell development GO:0060284 100 0.015
regulation of cardiac muscle tissue development GO:0055024 1 0.015
cellular response to starvation GO:0009267 1 0.015
heart looping GO:0001947 94 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
somatic muscle development GO:0007525 4 0.015
protein localization to nucleus GO:0034504 3 0.015
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
response to estrogen GO:0043627 27 0.014
negative regulation of reproductive process GO:2000242 3 0.014
primary neural tube formation GO:0014020 1 0.014
central nervous system neuron differentiation GO:0021953 74 0.014
neuron projection guidance GO:0097485 86 0.014
segment specification GO:0007379 12 0.014
regulation of hydrolase activity GO:0051336 28 0.014
developmental maturation GO:0021700 34 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
nuclear export GO:0051168 1 0.014
positive regulation of axon guidance GO:1902669 1 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
cell substrate adhesion GO:0031589 4 0.014
lateral line development GO:0048882 66 0.014
negative regulation of programmed cell death GO:0043069 58 0.014
long chain fatty acid biosynthetic process GO:0042759 1 0.014
muscle structure development GO:0061061 196 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.013
regulation of blood pressure GO:0008217 1 0.013
sensory organ development GO:0007423 393 0.013
nephron epithelium morphogenesis GO:0072088 1 0.013
kidney vasculature development GO:0061440 2 0.013
negative regulation of epithelial cell migration GO:0010633 1 0.013
heart process GO:0003015 71 0.013
multicellular organism reproduction GO:0032504 35 0.013
response to alcohol GO:0097305 14 0.013
rna export from nucleus GO:0006405 1 0.013
regulation of protein complex assembly GO:0043254 3 0.013
response to organic cyclic compound GO:0014070 51 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
regulation of cellular component movement GO:0051270 55 0.013
regulation of cell growth GO:0001558 29 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.013
embryonic skeletal system development GO:0048706 97 0.013
cell type specific apoptotic process GO:0097285 22 0.013
negative regulation of cell communication GO:0010648 96 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
positive regulation of response to stimulus GO:0048584 80 0.013
protein polymerization GO:0051258 4 0.013
regulation of cytokine production GO:0001817 3 0.012
nuclear transport GO:0051169 4 0.012
neural crest formation GO:0014029 14 0.012
regulation of cell migration GO:0030334 40 0.012
negative regulation of protein transport GO:0051224 3 0.012
peripheral nervous system neuron development GO:0048935 22 0.012
endothelial cell migration GO:0043542 19 0.012
developmental cell growth GO:0048588 52 0.012
neuron remodeling GO:0016322 1 0.012
collateral sprouting GO:0048668 9 0.012
facial nerve development GO:0021561 3 0.012
pigment cell development GO:0070285 3 0.012
positive regulation of neuron death GO:1901216 1 0.012
cellular response to oxygen levels GO:0071453 1 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
regulation of erythrocyte differentiation GO:0045646 2 0.012
negative regulation of metabolic process GO:0009892 86 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
response to vitamin GO:0033273 3 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
axon extension GO:0048675 45 0.012
positive regulation of cytokine production GO:0001819 2 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
spinal cord development GO:0021510 46 0.012
negative regulation of developmental process GO:0051093 65 0.011
response to inorganic substance GO:0010035 38 0.011
cellular component assembly GO:0022607 170 0.011
neuronal action potential GO:0019228 18 0.011
regulation of cell maturation GO:1903429 1 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
immune response GO:0006955 28 0.011
regulation of neuron differentiation GO:0045664 56 0.011
regulation of carbohydrate biosynthetic process GO:0043255 1 0.011
cell maturation GO:0048469 23 0.011
negative regulation of nucleic acid templated transcription GO:1903507 45 0.011
leukocyte migration GO:0050900 15 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
negative regulation of myeloid cell differentiation GO:0045638 1 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
peptide metabolic process GO:0006518 1 0.011
microtubule organizing center organization GO:0031023 1 0.011
regulation of anatomical structure size GO:0090066 33 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
post embryonic organ development GO:0048569 4 0.011
sympathetic ganglion development GO:0061549 2 0.011
cellular response to stress GO:0033554 62 0.011
negative regulation of multi organism process GO:0043901 3 0.011
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
cellular protein catabolic process GO:0044257 4 0.010
muscle organ development GO:0007517 101 0.010
cell recognition GO:0008037 19 0.010
cell growth GO:0016049 57 0.010
regulation of heart contraction GO:0008016 32 0.010
phosphorus metabolic process GO:0006793 109 0.010
actin cytoskeleton organization GO:0030036 63 0.010
cellular amine metabolic process GO:0044106 2 0.010
negative regulation of translation GO:0017148 1 0.010
negative regulation of rna metabolic process GO:0051253 48 0.010
cellular component disassembly GO:0022411 1 0.010
ovulation cycle process GO:0022602 2 0.010
cellular response to organic substance GO:0071310 105 0.010
inner ear receptor cell development GO:0060119 20 0.010
regulation of calcium ion transport GO:0051924 2 0.010
neuron neuron synaptic transmission GO:0007270 1 0.010
cell projection organization GO:0030030 284 0.010
inner ear morphogenesis GO:0042472 63 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010
digestive tract development GO:0048565 265 0.010
skeletal system development GO:0001501 181 0.010

zeb2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
sensory system disease DOID:0050155 0 0.016
organ system cancer DOID:0050686 0 0.016