Danio rerio

13 known processes

rap1a

RAP1A, member of RAS oncogene family

(Aliases: wu:fc66g06,zgc:86676)

rap1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vasculature development GO:0001944 278 0.196
positive regulation of cellular component biogenesis GO:0044089 3 0.183
system process GO:0003008 185 0.178
positive regulation of biological process GO:0048518 253 0.159
Fly
regulation of cell communication GO:0010646 232 0.147
rna localization GO:0006403 4 0.138
cellular component assembly GO:0022607 170 0.131
Fly
blood vessel development GO:0001568 246 0.111
meiotic cell cycle process GO:1903046 3 0.110
regulation of biological quality GO:0065008 263 0.106
Fly
regulation of multicellular organismal process GO:0051239 277 0.106
Fly
multicellular organism growth GO:0035264 4 0.104
nucleobase containing compound biosynthetic process GO:0034654 205 0.101
maintenance of location GO:0051235 4 0.099
regulation of cellular biosynthetic process GO:0031326 245 0.099
blood vessel morphogenesis GO:0048514 216 0.092
regulation of nucleic acid templated transcription GO:1903506 213 0.091
gene expression GO:0010467 252 0.085
nitrogen compound metabolic process GO:0006807 319 0.084
Yeast Fly
heterocycle metabolic process GO:0046483 290 0.081
Yeast Fly
neuron differentiation GO:0030182 353 0.080
regulation of multicellular organism growth GO:0040014 4 0.080
signal transduction GO:0007165 455 0.079
Fly
regulation of developmental process GO:0050793 247 0.078
Fly
regulation of response to stimulus GO:0048583 269 0.078
double strand break repair GO:0006302 3 0.077
regulation of macromolecule metabolic process GO:0060255 317 0.076
cellular aromatic compound metabolic process GO:0006725 295 0.075
Yeast Fly
organic cyclic compound metabolic process GO:1901360 301 0.074
Yeast Fly
organic substance biosynthetic process GO:1901576 289 0.074
single organism metabolic process GO:0044710 217 0.072
Yeast Fly
single organism localization GO:1902578 225 0.072
positive regulation of transport GO:0051050 2 0.071
protein metabolic process GO:0019538 183 0.071
negative regulation of cellular process GO:0048523 283 0.069
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.068
Yeast Fly
macromolecule biosynthetic process GO:0009059 227 0.063
positive regulation of dna metabolic process GO:0051054 1 0.060
regulation of multicellular organismal development GO:2000026 223 0.060
Fly
cell cycle g1 s phase transition GO:0044843 1 0.059
regulation of signaling GO:0023051 235 0.057
growth GO:0040007 174 0.057
protein polyubiquitination GO:0000209 4 0.056
biosynthetic process GO:0009058 294 0.054
larval development GO:0002164 2 0.053
meiotic nuclear division GO:0007126 4 0.053
cellular macromolecule biosynthetic process GO:0034645 224 0.052
positive regulation of chromatin modification GO:1903310 1 0.051
rna metabolic process GO:0016070 219 0.051
immune system process GO:0002376 241 0.049
Fly
stem cell proliferation GO:0072089 4 0.049
positive regulation of cell cycle GO:0045787 3 0.048
cilium assembly GO:0042384 58 0.047
regulation of meiotic cell cycle GO:0051445 1 0.046
negative regulation of cell cycle phase transition GO:1901988 5 0.045
organic substance transport GO:0071702 58 0.045
regulation of primary metabolic process GO:0080090 311 0.045
positive regulation of map kinase activity GO:0043406 3 0.044
regulation of apoptotic process GO:0042981 98 0.044
angiogenesis GO:0001525 158 0.043
nuclear transport GO:0051169 4 0.043
cellular component biogenesis GO:0044085 178 0.043
Fly
cellular component morphogenesis GO:0032989 336 0.043
Fly
epithelial cell differentiation GO:0030855 116 0.042
nucleic acid metabolic process GO:0090304 244 0.042
cell surface receptor signaling pathway GO:0007166 325 0.042
cellular biosynthetic process GO:0044249 286 0.042
response to uv GO:0009411 3 0.041
regulation of stem cell differentiation GO:2000736 4 0.041
cilium organization GO:0044782 71 0.041
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.041
generation of neurons GO:0048699 385 0.040
protein localization to nucleus GO:0034504 3 0.039
nucleic acid transport GO:0050657 2 0.039
regulation of cell death GO:0010941 103 0.038
regulation of transcription dna templated GO:0006355 213 0.038
regulation of signal transduction GO:0009966 225 0.038
regulation of cell differentiation GO:0045595 142 0.038
Fly
cellular protein modification process GO:0006464 100 0.038
response to stress GO:0006950 263 0.038
organonitrogen compound metabolic process GO:1901564 74 0.037
Yeast Fly
cell morphogenesis GO:0000902 289 0.037
Fly
regulation of catalytic activity GO:0050790 55 0.036
heart development GO:0007507 313 0.036
rna biosynthetic process GO:0032774 181 0.036
negative regulation of response to stimulus GO:0048585 104 0.035
g1 s transition of mitotic cell cycle GO:0000082 1 0.035
regulation of gene expression GO:0010468 265 0.035
digestive system development GO:0055123 289 0.035
hematopoietic or lymphoid organ development GO:0048534 191 0.035
Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.035
regulation of establishment of protein localization GO:0070201 4 0.035
positive regulation of metabolic process GO:0009893 108 0.035
regulation of cellular metabolic process GO:0031323 320 0.034
dna templated transcription elongation GO:0006354 3 0.034
cellular nitrogen compound metabolic process GO:0034641 290 0.034
Yeast Fly
regulation of reproductive process GO:2000241 4 0.034
organelle organization GO:0006996 227 0.034
embryonic digestive tract development GO:0048566 4 0.034
regulation of mitotic cell cycle GO:0007346 25 0.033
protein k63 linked ubiquitination GO:0070534 2 0.033
transport GO:0006810 220 0.032
regulation of anatomical structure morphogenesis GO:0022603 130 0.032
Fly
establishment of localization GO:0051234 244 0.031
positive regulation of apoptotic signaling pathway GO:2001235 1 0.031
regionalization GO:0003002 274 0.031
Zebrafish
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.031
regulation of embryonic development GO:0045995 47 0.031
Fly
regulation of biosynthetic process GO:0009889 250 0.030
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
heterocycle biosynthetic process GO:0018130 215 0.030
regulation of circadian rhythm GO:0042752 4 0.029
embryonic limb morphogenesis GO:0030326 2 0.029
developmental growth GO:0048589 166 0.029
stem cell differentiation GO:0048863 117 0.029
Fly
lipid storage GO:0019915 1 0.029
reproduction GO:0000003 40 0.029
cellular amine metabolic process GO:0044106 2 0.029
immune system development GO:0002520 191 0.029
Fly
aromatic compound biosynthetic process GO:0019438 217 0.028
mesenchyme development GO:0060485 127 0.028
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.028
hemopoiesis GO:0030097 183 0.028
Fly
synaptic growth at neuromuscular junction GO:0051124 2 0.028
regulation of cell development GO:0060284 100 0.028
maternal determination of anterior posterior axis embryo GO:0008358 4 0.028
regulation of protein transport GO:0051223 3 0.027
cell part morphogenesis GO:0032990 246 0.027
regulation of protein metabolic process GO:0051246 56 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.026
regulation of kinase activity GO:0043549 15 0.026
embryo development ending in birth or egg hatching GO:0009792 271 0.026
Zebrafish Fly
cellular amino acid metabolic process GO:0006520 7 0.026
positive regulation of protein complex assembly GO:0031334 2 0.026
response to chemical GO:0042221 320 0.026
ameboidal type cell migration GO:0001667 143 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
regulation of metabolic process GO:0019222 359 0.025
purine nucleoside monophosphate catabolic process GO:0009128 4 0.025
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.025
negative regulation of ras protein signal transduction GO:0046580 1 0.025
regulation of cellular component organization GO:0051128 86 0.025
Fly
dna metabolic process GO:0006259 27 0.025
protein stabilization GO:0050821 2 0.025
rna transport GO:0050658 2 0.025
macromolecule modification GO:0043412 111 0.025
regulation of mrna processing GO:0050684 3 0.024
transcription dna templated GO:0006351 181 0.024
cellular protein catabolic process GO:0044257 4 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.024
mitotic cell cycle embryonic GO:0045448 2 0.024
dna catabolic process GO:0006308 1 0.024
digestive tract development GO:0048565 265 0.024
cellular protein metabolic process GO:0044267 129 0.024
recombinational repair GO:0000725 1 0.024
organic cyclic compound biosynthetic process GO:1901362 223 0.023
positive regulation of jnk cascade GO:0046330 3 0.023
negative regulation of dna metabolic process GO:0051053 4 0.023
morphogenesis of an epithelium GO:0002009 333 0.023
Zebrafish Fly
cell projection organization GO:0030030 284 0.023
Fly
protein import into nucleus GO:0006606 3 0.023
positive regulation of multicellular organismal process GO:0051240 52 0.023
regulation of cell shape GO:0008360 1 0.023
Fly
golgi vesicle transport GO:0048193 3 0.022
regulation of histone methylation GO:0031060 3 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
protein modification process GO:0036211 100 0.022
single organism transport GO:0044765 206 0.022
regulation of neuron differentiation GO:0045664 56 0.022
regulation of tube size GO:0035150 2 0.022
eye development GO:0001654 277 0.022
Fly
regulation of intracellular protein transport GO:0033157 3 0.022
establishment of rna localization GO:0051236 3 0.021
fertilization GO:0009566 3 0.021
neuron projection development GO:0031175 180 0.021
regulation of neurogenesis GO:0050767 87 0.021
regulation of nervous system development GO:0051960 90 0.021
response to bacterium GO:0009617 58 0.021
response to wounding GO:0009611 116 0.021
energy reserve metabolic process GO:0006112 2 0.021
macromolecule localization GO:0033036 54 0.021
regulation of protein catabolic process GO:0042176 1 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
regeneration GO:0031099 91 0.021
adult behavior GO:0030534 2 0.021
positive regulation of developmental process GO:0051094 50 0.021
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.020
organic acid metabolic process GO:0006082 31 0.020
cell projection morphogenesis GO:0048858 244 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
single organism organelle organization GO:1902589 199 0.020
cell morphogenesis involved in differentiation GO:0000904 195 0.020
positive regulation of stress activated mapk cascade GO:0032874 3 0.020
regulation of dna metabolic process GO:0051052 11 0.020
mitotic dna integrity checkpoint GO:0044774 4 0.020
negative regulation of signal transduction GO:0009968 94 0.019
phagocytosis GO:0006909 3 0.019
regulation of binding GO:0051098 3 0.019
protein k48 linked ubiquitination GO:0070936 1 0.019
mitotic dna damage checkpoint GO:0044773 4 0.019
gastrulation GO:0007369 208 0.019
regulation of protein complex assembly GO:0043254 3 0.019
regulation of growth GO:0040008 42 0.019
response to external stimulus GO:0009605 264 0.018
positive regulation of chromosome organization GO:2001252 1 0.018
negative regulation of chromosome organization GO:2001251 1 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
protein complex assembly GO:0006461 30 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
regulation of axonogenesis GO:0050770 32 0.018
neuron development GO:0048666 262 0.018
nucleic acid templated transcription GO:0097659 181 0.018
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.018
lateral inhibition GO:0046331 1 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
Yeast Fly
modification dependent protein catabolic process GO:0019941 3 0.018
single fertilization GO:0007338 3 0.018
liver development GO:0001889 96 0.018
response to corticosteroid GO:0031960 1 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.017
hepaticobiliary system development GO:0061008 98 0.017
er to golgi vesicle mediated transport GO:0006888 1 0.017
nucleobase containing compound transport GO:0015931 2 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
positive regulation of histone modification GO:0031058 1 0.017
small molecule metabolic process GO:0044281 77 0.017
Yeast Fly
negative regulation of biosynthetic process GO:0009890 55 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.016
negative regulation of signaling GO:0023057 96 0.016
programmed cell death GO:0012501 119 0.016
response to biotic stimulus GO:0009607 97 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
chemosensory behavior GO:0007635 1 0.016
carbohydrate derivative metabolic process GO:1901135 61 0.016
Yeast Fly
guanosine containing compound catabolic process GO:1901069 2 0.016
Yeast Fly
nuclear pore organization GO:0006999 2 0.016
oocyte anterior posterior axis specification GO:0007314 4 0.016
gland development GO:0048732 143 0.016
regulation of dna templated transcription elongation GO:0032784 3 0.016
multicellular organism reproduction GO:0032504 35 0.016
germ line stem cell division GO:0042078 1 0.015
nuclear import GO:0051170 3 0.015
establishment of localization in cell GO:0051649 77 0.015
cell death GO:0008219 121 0.015
locomotion GO:0040011 313 0.015
Fly
macromolecular complex assembly GO:0065003 35 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
protein complex localization GO:0031503 1 0.015
spliceosomal complex assembly GO:0000245 1 0.015
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.015
negative regulation of biological process GO:0048519 304 0.015
Fly
regulation of transmembrane transporter activity GO:0022898 2 0.015
positive regulation of secretion GO:0051047 1 0.015
protein import GO:0017038 3 0.015
embryonic digestive tract morphogenesis GO:0048557 3 0.014
gtp metabolic process GO:0046039 4 0.014
Yeast Fly
regulation of cytoplasmic transport GO:1903649 4 0.014
negative regulation of neuron projection regeneration GO:0070571 4 0.014
regulation of programmed cell death GO:0043067 101 0.014
negative regulation of cellular component organization GO:0051129 16 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
single organism nuclear import GO:1902593 3 0.014
central nervous system development GO:0007417 387 0.014
taxis GO:0042330 109 0.014
oxoacid metabolic process GO:0043436 31 0.014
circulatory system process GO:0003013 87 0.014
mitotic cell cycle GO:0000278 64 0.014
positive regulation of translation GO:0045727 1 0.014
spermatid differentiation GO:0048515 2 0.014
dna biosynthetic process GO:0071897 3 0.014
phosphorylation GO:0016310 69 0.014
positive regulation of catabolic process GO:0009896 4 0.014
regulation of metal ion transport GO:0010959 4 0.013
dna templated transcription initiation GO:0006352 1 0.013
neuron projection morphogenesis GO:0048812 161 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
cell motility GO:0048870 244 0.013
Fly
small gtpase mediated signal transduction GO:0007264 8 0.013
Fly
death GO:0016265 121 0.013
reactive oxygen species biosynthetic process GO:1903409 1 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
meiosis i GO:0007127 1 0.013
regulation of cell cycle GO:0051726 52 0.013
mrna transport GO:0051028 2 0.013
positive regulation of signaling GO:0023056 56 0.013
g2 m transition of mitotic cell cycle GO:0000086 4 0.013
regulation of gene expression epigenetic GO:0040029 11 0.013
negative regulation of chromatin modification GO:1903309 1 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
negative regulation of dna replication GO:0008156 2 0.013
response to external biotic stimulus GO:0043207 97 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
cellular localization GO:0051641 97 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
aging GO:0007568 2 0.012
gtp catabolic process GO:0006184 2 0.012
Yeast Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
digestive tract morphogenesis GO:0048546 231 0.012
prevention of polyspermy GO:0060468 1 0.012
negative regulation of gene expression GO:0010629 65 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
blood circulation GO:0008015 87 0.012
regulation of response to stress GO:0080134 36 0.012
macromolecule methylation GO:0043414 19 0.012
response to drug GO:0042493 3 0.012
mitotic g2 dna damage checkpoint GO:0007095 3 0.012
regulation of synapse organization GO:0050807 3 0.012
negative regulation of cell communication GO:0010648 96 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
camera type eye development GO:0043010 222 0.012
positive regulation of cell communication GO:0010647 56 0.012
stem cell division GO:0017145 1 0.012
negative regulation of mitosis GO:0045839 3 0.012
alternative mrna splicing via spliceosome GO:0000380 1 0.012
cell proliferation GO:0008283 80 0.012
regulation of developmental growth GO:0048638 38 0.012
response to other organism GO:0051707 97 0.012
pole plasm assembly GO:0007315 4 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
transcription from rna polymerase iii promoter GO:0006383 1 0.011
protein targeting to nucleus GO:0044744 3 0.011
cellular response to external stimulus GO:0071496 2 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
alcohol biosynthetic process GO:0046165 2 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
endodermal cell fate determination GO:0007493 2 0.011
microtubule based process GO:0007017 60 0.011
sensory organ development GO:0007423 393 0.011
Fly
response to nutrient GO:0007584 3 0.011
cellular component disassembly GO:0022411 1 0.011
regulation of transporter activity GO:0032409 2 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
heart morphogenesis GO:0003007 156 0.011
spliceosomal snrnp assembly GO:0000387 2 0.011
nik nf kappab signaling GO:0038061 1 0.011
negative regulation of reproductive process GO:2000242 3 0.011
epiboly GO:0090504 41 0.011
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.011
behavior GO:0007610 74 0.011
negative regulation of nuclear division GO:0051784 3 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
regulation of synapse assembly GO:0051963 3 0.011
apoptotic process GO:0006915 116 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
negative regulation of axon regeneration GO:0048681 4 0.010
secondary metabolic process GO:0019748 3 0.010
peptidyl lysine trimethylation GO:0018023 1 0.010
convergent extension GO:0060026 118 0.010
Zebrafish
ribonucleoside monophosphate catabolic process GO:0009158 4 0.010
negative regulation of cell differentiation GO:0045596 46 0.010
Fly
dna repair GO:0006281 6 0.010
positive regulation of cellular process GO:0048522 201 0.010
Fly
amine metabolic process GO:0009308 2 0.010
regulation of dna replication GO:0006275 3 0.010
regulation of glial cell differentiation GO:0045685 4 0.010
regulation of cytokine production GO:0001817 3 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
regulation of calcium ion transport GO:0051924 2 0.010
ubiquitin dependent protein catabolic process GO:0006511 3 0.010
purine containing compound metabolic process GO:0072521 29 0.010
Yeast Fly
telomere organization GO:0032200 1 0.010
epidermis development GO:0008544 48 0.010
Worm

rap1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.011
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011