Danio rerio

0 known processes

hoxb4a

homeo box B4a

(Aliases: zf13,Z-17,ZF-13,hoxb4,HOX-B4)

hoxb4a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neuromast primordium migration GO:0048883 12 0.971
Zebrafish
skeletal system development GO:0001501 181 0.951
Mouse
central nervous system development GO:0007417 387 0.867
Zebrafish Fly
embryonic organ morphogenesis GO:0048562 274 0.795
Mouse
embryonic organ development GO:0048568 381 0.793
Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.732
Mouse
embryonic pectoral fin morphogenesis GO:0035118 24 0.732
Zebrafish
definitive hemopoiesis GO:0060216 18 0.702
Mouse
embryonic viscerocranium morphogenesis GO:0048703 52 0.691
posterior lateral line neuromast primordium migration GO:0048920 12 0.664
Zebrafish
pectoral fin development GO:0033339 50 0.654
Zebrafish
head development GO:0060322 303 0.642
Zebrafish Fly
posterior lateral line development GO:0048916 38 0.639
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.568
Human Mouse Fly
appendage morphogenesis GO:0035107 56 0.561
Zebrafish
mechanosensory lateral line system development GO:0048881 49 0.538
Zebrafish
brain development GO:0007420 293 0.538
Zebrafish Fly
lateral line system development GO:0048925 76 0.530
Zebrafish
cell migration GO:0016477 237 0.510
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.481
Human Mouse Fly
pectoral fin morphogenesis GO:0035138 29 0.467
Zebrafish
skeletal system morphogenesis GO:0048705 102 0.447
Mouse
apoptotic process involved in morphogenesis GO:0060561 2 0.445
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.439
Mouse
regionalization GO:0003002 274 0.438
Mouse Fly
regulation of gene expression GO:0010468 265 0.432
Human Mouse Fly
regulation of multicellular organismal process GO:0051239 277 0.420
cranial nerve morphogenesis GO:0021602 15 0.419
immune system process GO:0002376 241 0.377
Human Mouse
rhombomere boundary formation GO:0021654 10 0.373
cartilage development GO:0051216 96 0.372
apoptotic process involved in development GO:1902742 2 0.340
Fly
cranial nerve development GO:0021545 42 0.338
olfactory bulb development GO:0021772 4 0.338
organic cyclic compound biosynthetic process GO:1901362 223 0.336
Human Mouse Fly
chordate embryonic development GO:0043009 271 0.333
Mouse
heart development GO:0007507 313 0.333
Zebrafish
mesodermal cell fate specification GO:0007501 12 0.312
olfactory lobe development GO:0021988 4 0.312
cell fate specification GO:0001708 68 0.293
Zebrafish
regulation of developmental process GO:0050793 247 0.288
Human Fly
rna biosynthetic process GO:0032774 181 0.288
Human Mouse Fly
localization of cell GO:0051674 244 0.287
Zebrafish
regulation of cell development GO:0060284 100 0.285
Fly
fin development GO:0033333 77 0.270
Zebrafish
sensory system development GO:0048880 76 0.268
Zebrafish
fin morphogenesis GO:0033334 53 0.268
Zebrafish
digestive system development GO:0055123 289 0.259
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.243
Human Mouse Fly
embryonic skeletal system development GO:0048706 97 0.240
Mouse
locomotion GO:0040011 313 0.232
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.226
Mouse
immune system development GO:0002520 191 0.224
Human Mouse
lateral line development GO:0048882 66 0.217
Zebrafish
epithelial tube morphogenesis GO:0060562 148 0.214
positive regulation of rna biosynthetic process GO:1902680 57 0.211
Human Fly
cell migration in hindbrain GO:0021535 7 0.210
regulation of transcription dna templated GO:0006355 213 0.207
Human Mouse Fly
rna metabolic process GO:0016070 219 0.195
Human Mouse Fly
thyroid gland development GO:0030878 12 0.189
rhombomere 4 development GO:0021570 5 0.183
mesodermal cell differentiation GO:0048333 21 0.183
regulation of cell communication GO:0010646 232 0.183
signal transduction GO:0007165 455 0.176
nerve development GO:0021675 45 0.174
negative regulation of myeloid cell differentiation GO:0045638 1 0.173
death GO:0016265 121 0.171
Fly
tube morphogenesis GO:0035239 349 0.170
rhombomere development GO:0021546 19 0.164
hindbrain development GO:0030902 91 0.159
mesoderm morphogenesis GO:0048332 51 0.158
hematopoietic or lymphoid organ development GO:0048534 191 0.156
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.152
Human Mouse Fly
primitive hemopoiesis GO:0060215 27 0.148
nitrogen compound metabolic process GO:0006807 319 0.147
Human Mouse Fly
regulation of nervous system development GO:0051960 90 0.147
regulation of cell differentiation GO:0045595 142 0.145
Human Fly
erythrocyte differentiation GO:0030218 54 0.139
ectodermal placode development GO:0071696 37 0.139
regulation of mesoderm development GO:2000380 11 0.136
neuron development GO:0048666 262 0.131
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.130
Human Fly
regulation of molecular function GO:0065009 70 0.126
nucleobase containing compound metabolic process GO:0006139 274 0.126
Human Mouse Fly
olfactory placode development GO:0071698 12 0.122
sensory organ development GO:0007423 393 0.120
dendrite guidance GO:0070983 0 0.118
regulation of nitrogen compound metabolic process GO:0051171 251 0.117
Human Mouse Fly
positive regulation of gene expression GO:0010628 71 0.117
Human Fly
forebrain development GO:0030900 96 0.117
nucleobase containing compound biosynthetic process GO:0034654 205 0.117
Human Mouse Fly
cardiocyte differentiation GO:0035051 44 0.117
Zebrafish
cardiogenic plate morphogenesis GO:0003142 1 0.115
mechanoreceptor differentiation GO:0042490 37 0.115
cellular nitrogen compound metabolic process GO:0034641 290 0.112
Human Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.112
Human Mouse Fly
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.111
embryonic cranial skeleton morphogenesis GO:0048701 90 0.110
rhombomere formation GO:0021594 12 0.110
regulation of biological quality GO:0065008 263 0.109
appendage development GO:0048736 80 0.106
Zebrafish
endocrine system development GO:0035270 65 0.105
Zebrafish
stem cell proliferation GO:0072089 4 0.104
mesoderm formation GO:0001707 43 0.104
regulation of cell death GO:0010941 103 0.101
Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.099
forebrain anterior posterior pattern specification GO:0021797 3 0.099
aromatic compound biosynthetic process GO:0019438 217 0.098
Human Mouse Fly
negative regulation of response to stimulus GO:0048585 104 0.097
regulation of mesodermal cell fate specification GO:0042661 9 0.097
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.097
Human Fly
cellular aromatic compound metabolic process GO:0006725 295 0.096
Human Mouse Fly
biosynthetic process GO:0009058 294 0.096
Human Mouse Fly
primary neural tube formation GO:0014020 1 0.094
generation of neurons GO:0048699 385 0.093
regulation of metabolic process GO:0019222 359 0.093
Human Mouse Fly
taxis GO:0042330 109 0.091
regulation of photoreceptor cell differentiation GO:0046532 2 0.091
regulation of rna biosynthetic process GO:2001141 213 0.090
Human Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.089
Human Mouse Fly
axonogenesis GO:0007409 152 0.087
cellular component movement GO:0006928 335 0.085
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.085
Human Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.084
Human Mouse Fly
epidermal cell differentiation GO:0009913 36 0.083
regulation of stem cell proliferation GO:0072091 2 0.081
regulation of erythrocyte differentiation GO:0045646 2 0.081
telencephalon development GO:0021537 14 0.080
regeneration GO:0031099 91 0.080
positive regulation of rna metabolic process GO:0051254 59 0.080
Human Fly
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.080
pancreas development GO:0031016 84 0.079
Zebrafish
negative regulation of axon guidance GO:1902668 1 0.079
skin development GO:0043588 54 0.077
regulation of signaling GO:0023051 235 0.076
segmentation GO:0035282 97 0.075
Fly
posterior lateral line system development GO:0048915 46 0.075
Zebrafish
cell motility GO:0048870 244 0.074
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.074
Human Mouse Fly
embryonic appendage morphogenesis GO:0035113 30 0.074
Zebrafish
negative regulation of developmental process GO:0051093 65 0.073
transcription dna templated GO:0006351 181 0.072
Human Mouse Fly
specification of symmetry GO:0009799 204 0.072
mechanosensory behavior GO:0007638 2 0.071
regulation of cellular biosynthetic process GO:0031326 245 0.071
Human Mouse Fly
cell projection organization GO:0030030 284 0.071
regulation of apoptotic process GO:0042981 98 0.070
Fly
system process GO:0003008 185 0.070
negative regulation of angiogenesis GO:0016525 7 0.069
rhythmic process GO:0048511 21 0.069
innervation GO:0060384 3 0.068
polarized epithelial cell differentiation GO:0030859 4 0.068
single organism transport GO:0044765 206 0.068
neuron projection morphogenesis GO:0048812 161 0.068
regulation of neuron projection development GO:0010975 40 0.067
regulation of neurogenesis GO:0050767 87 0.066
neuromast development GO:0048884 46 0.065
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.064
positive regulation of nucleic acid templated transcription GO:1903508 57 0.064
Human Fly
positive regulation of metabolic process GO:0009893 108 0.064
Human Fly
peripheral nervous system neuron differentiation GO:0048934 28 0.064
positive regulation of cellular process GO:0048522 201 0.063
Human Fly
neural keel formation GO:0014025 1 0.063
regulation of binding GO:0051098 3 0.062
anatomical structure arrangement GO:0048532 2 0.062
regulation of anatomical structure morphogenesis GO:0022603 130 0.061
Fly
regulation of cellular metabolic process GO:0031323 320 0.060
Human Mouse Fly
muscle cell development GO:0055001 115 0.060
positive regulation of biological process GO:0048518 253 0.059
Human Fly
erythrocyte homeostasis GO:0034101 55 0.059
renal system development GO:0072001 94 0.059
single organism localization GO:1902578 225 0.058
negative regulation of metabolic process GO:0009892 86 0.058
Mouse Fly
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.058
Human Fly
gene expression GO:0010467 252 0.058
Human Mouse Fly
synaptic target recognition GO:0008039 1 0.057
regulation of epithelial cell proliferation GO:0050678 3 0.057
neuroblast differentiation GO:0014016 1 0.057
post anal tail morphogenesis GO:0036342 19 0.057
mesoderm development GO:0007498 88 0.057
negative regulation of cellular process GO:0048523 283 0.056
Mouse Fly
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.056
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.056
Human Mouse Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.055
Mouse Fly
neuroblast proliferation GO:0007405 2 0.054
angiogenesis GO:0001525 158 0.054
cellular macromolecule metabolic process GO:0044260 391 0.053
Human Mouse Fly
vasculature development GO:0001944 278 0.053
axonogenesis involved in innervation GO:0060385 1 0.053
heterocycle metabolic process GO:0046483 290 0.052
Human Mouse Fly
eye morphogenesis GO:0048592 144 0.052
developmental growth involved in morphogenesis GO:0060560 86 0.052
somatic stem cell maintenance GO:0035019 1 0.051
eye development GO:0001654 277 0.051
sensory neuron axon guidance GO:0097374 3 0.051
neuron differentiation GO:0030182 353 0.051
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.051
heterocycle biosynthetic process GO:0018130 215 0.051
Human Mouse Fly
myeloid cell differentiation GO:0030099 86 0.051
cytoskeleton organization GO:0007010 96 0.050
cell projection morphogenesis GO:0048858 244 0.050
cartilage morphogenesis GO:0060536 13 0.050
regulation of axonogenesis GO:0050770 32 0.050
stem cell division GO:0017145 1 0.050
Mouse
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.049
regulation of response to stimulus GO:0048583 269 0.049
response to external stimulus GO:0009605 264 0.048
formation of primary germ layer GO:0001704 62 0.048
exocrine system development GO:0035272 28 0.048
Zebrafish
cellular lipid catabolic process GO:0044242 3 0.048
phagocytosis GO:0006909 3 0.048
digestive tract morphogenesis GO:0048546 231 0.047
myotube cell development GO:0014904 35 0.047
cellular protein metabolic process GO:0044267 129 0.047
cilium assembly GO:0042384 58 0.047
adult behavior GO:0030534 2 0.047
positive regulation of programmed cell death GO:0043068 29 0.047
Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.046
Human Mouse Fly
neuroblast fate commitment GO:0014017 1 0.046
rhombomere 4 morphogenesis GO:0021661 5 0.046
neuron projection regeneration GO:0031102 16 0.046
positive regulation of epithelial cell proliferation GO:0050679 1 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.045
Human Mouse Fly
auditory receptor cell fate commitment GO:0009912 4 0.045
bone development GO:0060348 14 0.045
Mouse
anterior lateral line nerve development GO:0048909 4 0.045
neuron projection guidance GO:0097485 86 0.045
negative regulation of biosynthetic process GO:0009890 55 0.045
Mouse Fly
regulation of hydrolase activity GO:0051336 28 0.045
dorsal ventral pattern formation GO:0009953 125 0.044
facial nucleus development GO:0021754 7 0.044
positive regulation of embryonic development GO:0040019 3 0.044
regulation of biosynthetic process GO:0009889 250 0.043
Human Mouse Fly
sensory perception of pain GO:0019233 1 0.043
cell fate commitment GO:0045165 99 0.043
Zebrafish
cellular biosynthetic process GO:0044249 286 0.043
Human Mouse Fly
inner ear receptor cell differentiation GO:0060113 29 0.042
organonitrogen compound metabolic process GO:1901564 74 0.042
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.042
regulation of reproductive process GO:2000241 4 0.042
axon extension GO:0048675 45 0.042
mesodermal cell fate commitment GO:0001710 14 0.041
exocrine pancreas development GO:0031017 28 0.041
Zebrafish
hindbrain morphogenesis GO:0021575 22 0.041
regulation of circadian rhythm GO:0042752 4 0.041
negative regulation of biological process GO:0048519 304 0.041
Mouse Fly
negative regulation of cellular biosynthetic process GO:0031327 55 0.041
Mouse Fly
transport GO:0006810 220 0.041
gastrulation GO:0007369 208 0.041
forebrain cell migration GO:0021885 1 0.040
cell cell signaling GO:0007267 52 0.040
embryonic heart tube formation GO:0003144 1 0.040
negative regulation of neuron projection development GO:0010977 9 0.040
aging GO:0007568 2 0.040
regulation of organ morphogenesis GO:2000027 35 0.040
regulation of inner ear receptor cell differentiation GO:2000980 1 0.039
muscle fiber development GO:0048747 52 0.039
determination of intestine left right asymmetry GO:0071908 2 0.039
chemotaxis GO:0006935 104 0.038
axon development GO:0061564 166 0.038
regulation of stem cell differentiation GO:2000736 4 0.038
Human
larval development GO:0002164 2 0.038
regulation of wnt signaling pathway GO:0030111 53 0.038
primitive erythrocyte differentiation GO:0060319 5 0.037
establishment of localization GO:0051234 244 0.037
synaptic growth at neuromuscular junction GO:0051124 2 0.037
regulation of programmed cell death GO:0043067 101 0.037
Fly
determination of left right symmetry GO:0007368 179 0.036
regulation of gastrulation GO:0010470 24 0.036
stem cell differentiation GO:0048863 117 0.036
Human Zebrafish
positive regulation of cell differentiation GO:0045597 30 0.036
Human Fly
regulation of tube size GO:0035150 2 0.035
negative regulation of neurogenesis GO:0050768 20 0.035
cellular component biogenesis GO:0044085 178 0.035
multicellular organism growth GO:0035264 4 0.035
cell surface receptor signaling pathway GO:0007166 325 0.034
intracellular signal transduction GO:0035556 85 0.034
neuron fate determination GO:0048664 2 0.034
neuron projection extension GO:1990138 45 0.033
nucleic acid metabolic process GO:0090304 244 0.033
Human Mouse Fly
rhombomere morphogenesis GO:0021593 17 0.033
negative regulation of neuron differentiation GO:0045665 10 0.033
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.033
protein targeting to nucleus GO:0044744 3 0.033
connective tissue development GO:0061448 99 0.032
regulation of localization GO:0032879 104 0.032
apoptotic process GO:0006915 116 0.032
Fly
type b pancreatic cell development GO:0003323 4 0.032
sympathetic ganglion development GO:0061549 2 0.032
motor neuron axon guidance GO:0008045 23 0.030
axon guidance GO:0007411 86 0.030
stem cell maintenance GO:0019827 4 0.030
regulation of signal transduction GO:0009966 225 0.030
peripheral nervous system development GO:0007422 55 0.030
developmental growth GO:0048589 166 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.029
vestibular receptor cell development GO:0060118 3 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.029
Mouse Fly
single organism membrane organization GO:0044802 20 0.029
glossopharyngeal nerve development GO:0021563 1 0.029
positive regulation of neurogenesis GO:0050769 24 0.029
carboxylic acid catabolic process GO:0046395 3 0.029
cellular component assembly involved in morphogenesis GO:0010927 107 0.028
growth plate cartilage development GO:0003417 2 0.028
homeostatic process GO:0042592 142 0.028
cranial nerve formation GO:0021603 13 0.028
blood circulation GO:0008015 87 0.028
somite development GO:0061053 96 0.028
posterior lateral line neuromast development GO:0048919 20 0.027
endocrine pancreas development GO:0031018 27 0.027
Zebrafish
response to light stimulus GO:0009416 46 0.027
cellular response to organic substance GO:0071310 105 0.027
regulation of neuron differentiation GO:0045664 56 0.027
negative regulation of gene expression GO:0010629 65 0.027
Mouse Fly
olfactory bulb axon guidance GO:0071678 3 0.027
regulation of embryonic development GO:0045995 47 0.027
regulation of angiogenesis GO:0045765 26 0.027
protein localization to membrane GO:0072657 9 0.027
facial nerve morphogenesis GO:0021610 1 0.027
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.027
positive regulation of transport GO:0051050 2 0.026
auditory receptor cell fate determination GO:0042668 2 0.026
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.026
regulation of purine nucleotide catabolic process GO:0033121 2 0.026
positive regulation of cell death GO:0010942 29 0.026
Fly
regulation of synaptic plasticity GO:0048167 1 0.026
regulation of organ growth GO:0046620 3 0.026
nephron development GO:0072006 31 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
angioblast cell migration GO:0035476 9 0.025
embryonic epithelial tube formation GO:0001838 17 0.025
homeostasis of number of cells GO:0048872 62 0.025
bone morphogenesis GO:0060349 11 0.025
epithelial tube formation GO:0072175 19 0.025
response to stress GO:0006950 263 0.025
positive regulation of notch signaling pathway GO:0045747 3 0.024
epidermis development GO:0008544 48 0.024
small molecule catabolic process GO:0044282 3 0.024
myotube differentiation GO:0014902 45 0.024
regulation of mechanoreceptor differentiation GO:0045631 1 0.024
positive regulation of gastrulation GO:2000543 2 0.024
positive regulation of cell development GO:0010720 25 0.024
Fly
lipid storage GO:0019915 1 0.023
cardioblast differentiation GO:0010002 9 0.023
Zebrafish
protein metabolic process GO:0019538 183 0.023
epithelial cell morphogenesis GO:0003382 2 0.023
endochondral bone growth GO:0003416 2 0.023
inner ear receptor cell fate commitment GO:0060120 4 0.023
nuclear transport GO:0051169 4 0.022
cell morphogenesis GO:0000902 289 0.022
peptide metabolic process GO:0006518 1 0.022
cerebellar cortex formation GO:0021697 5 0.022
positive regulation of nervous system development GO:0051962 25 0.022
negative regulation of epithelial cell migration GO:0010633 1 0.021
specification of organ identity GO:0010092 2 0.021
cellular response to molecule of bacterial origin GO:0071219 3 0.021
positive regulation of transcription dna templated GO:0045893 57 0.021
Human Fly
negative regulation of rna metabolic process GO:0051253 48 0.021
Mouse Fly
wnt signaling pathway GO:0016055 80 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.021
cell part morphogenesis GO:0032990 246 0.020
circulatory system process GO:0003013 87 0.020
hemopoiesis GO:0030097 183 0.020
Human Mouse
organic substance transport GO:0071702 58 0.020
positive regulation of biosynthetic process GO:0009891 68 0.020
Human Fly
epithelial cell development GO:0002064 42 0.019
cell differentiation in hindbrain GO:0021533 5 0.019
regulation of mesenchymal cell proliferation GO:0010464 1 0.019
endodermal cell fate determination GO:0007493 2 0.019
regulation of developmental growth GO:0048638 38 0.019
single organism nuclear import GO:1902593 3 0.019
negative regulation of signal transduction GO:0009968 94 0.019
forebrain neuron development GO:0021884 7 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
inner ear development GO:0048839 126 0.019
positive regulation of reproductive process GO:2000243 2 0.019
morphogenesis of embryonic epithelium GO:0016331 30 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
protein localization to nucleus GO:0034504 3 0.019
positive regulation of mesodermal cell fate specification GO:0048337 1 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
determination of heart left right asymmetry GO:0061371 117 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
positive regulation of neuron death GO:1901216 1 0.018
stem cell fate commitment GO:0048865 1 0.018
endocardium formation GO:0060214 1 0.018
b cell activation GO:0042113 2 0.018
erythrocyte development GO:0048821 24 0.018
regulation of calcium mediated signaling GO:0050848 1 0.018
negative regulation of cell communication GO:0010648 96 0.018
regulation of receptor mediated endocytosis GO:0048259 4 0.018
macromolecule localization GO:0033036 54 0.018
muscle cell migration GO:0014812 4 0.018
response to wounding GO:0009611 116 0.018
central nervous system neuron development GO:0021954 29 0.018
regulation of vasculature development GO:1901342 33 0.018
single organism cellular localization GO:1902580 46 0.018
skeletal muscle tissue development GO:0007519 67 0.017
cell differentiation involved in kidney development GO:0061005 13 0.017
programmed cell death GO:0012501 119 0.017
Fly
auditory receptor cell fate specification GO:0042667 2 0.017
negative regulation of vasculature development GO:1901343 8 0.017
negative regulation of multicellular organismal process GO:0051241 69 0.017
retina development in camera type eye GO:0060041 146 0.017
positive regulation of neuron apoptotic process GO:0043525 1 0.017
regulation of endothelial cell differentiation GO:0045601 3 0.017
cerebellar granular layer morphogenesis GO:0021683 3 0.017
regulation of cell motility GO:2000145 46 0.017
negative regulation of signaling GO:0023057 96 0.017
embryonic heart tube development GO:0035050 133 0.017
metencephalon development GO:0022037 27 0.016
positive regulation of secretion GO:0051047 1 0.016
tissue regeneration GO:0042246 74 0.016
negative regulation of cell migration GO:0030336 17 0.016
positive regulation of endothelial cell differentiation GO:0045603 2 0.016
wound healing GO:0042060 90 0.016
neuron projection development GO:0031175 180 0.016
ectoderm development GO:0007398 9 0.016
mesenchyme development GO:0060485 127 0.016
regulation of intracellular signal transduction GO:1902531 57 0.016
negative regulation of nervous system development GO:0051961 22 0.016
regulation of synapse organization GO:0050807 3 0.016
somatic muscle development GO:0007525 4 0.016
cell proliferation GO:0008283 80 0.016
Zebrafish Mouse
negative regulation of cellular metabolic process GO:0031324 77 0.016
Mouse Fly
liver development GO:0001889 96 0.016
heart morphogenesis GO:0003007 156 0.016
synaptic vesicle transport GO:0048489 1 0.015
response to hydrogen peroxide GO:0042542 3 0.015
sensory organ morphogenesis GO:0090596 200 0.015
synaptic vesicle localization GO:0097479 1 0.015
ear development GO:0043583 127 0.015
retinoic acid metabolic process GO:0042573 9 0.015
positive regulation of epithelial cell differentiation GO:0030858 2 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.015
actomyosin structure organization GO:0031032 53 0.015
sexual reproduction GO:0019953 36 0.015
cellular component assembly GO:0022607 170 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
renal tubule morphogenesis GO:0061333 1 0.015
positive regulation of developmental process GO:0051094 50 0.015
Human Fly
establishment of synaptic vesicle localization GO:0097480 1 0.015
actin cytoskeleton organization GO:0030036 63 0.015
skeletal muscle organ development GO:0060538 78 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
positive regulation of apoptotic process GO:0043065 29 0.015
Fly
neuromast hair cell differentiation GO:0048886 12 0.014
single organism organelle organization GO:1902589 199 0.014
response to alkaloid GO:0043279 2 0.014
negative regulation of transcription dna templated GO:0045892 45 0.014
Mouse Fly
central nervous system neuron differentiation GO:0021953 74 0.014
notch signaling pathway GO:0007219 35 0.014
intracellular estrogen receptor signaling pathway GO:0030520 3 0.014
hair cell differentiation GO:0035315 32 0.014
response to bacterium GO:0009617 58 0.014
neural tube formation GO:0001841 16 0.014
determination of bilateral symmetry GO:0009855 204 0.014
regulation of synapse assembly GO:0051963 3 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
protein heterooligomerization GO:0051291 1 0.014
positive regulation of cell fate specification GO:0042660 1 0.014
cell proliferation in forebrain GO:0021846 3 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
cellular component morphogenesis GO:0032989 336 0.013
cellular localization GO:0051641 97 0.013
calcium mediated signaling GO:0019722 2 0.013
regulation of inflammatory response GO:0050727 2 0.013
neurotransmitter transport GO:0006836 2 0.013
cell death GO:0008219 121 0.013
Fly
smooth muscle contraction GO:0006939 2 0.013
morphogenesis of a branching structure GO:0001763 21 0.013
negative regulation of collateral sprouting GO:0048671 2 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
digestive tract development GO:0048565 265 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
cerebellar granule cell differentiation GO:0021707 3 0.013
regulation of cell fate specification GO:0042659 20 0.013
embryonic hemopoiesis GO:0035162 53 0.013
blood vessel development GO:0001568 246 0.013
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.013
facial nerve development GO:0021561 3 0.013
keratinocyte differentiation GO:0030216 0 0.013
multicellular organismal signaling GO:0035637 22 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
establishment of protein localization to organelle GO:0072594 4 0.012
regulation of cell projection assembly GO:0060491 4 0.012
preganglionic parasympathetic nervous system development GO:0021783 6 0.012

hoxb4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.029
disease of cellular proliferation DOID:14566 0 0.026
auditory system disease DOID:2742 0 0.024
nonsyndromic deafness DOID:0050563 0 0.024
sensory system disease DOID:0050155 0 0.024
cancer DOID:162 0 0.020
organ system cancer DOID:0050686 0 0.020
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.018
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014